interleukin-8 and alvocidib

interleukin-8 has been researched along with alvocidib* in 1 studies

Other Studies

1 other study(ies) available for interleukin-8 and alvocidib

Article	Year
Neutrophil Extracellular Trap Formation Is Independent of De Novo Gene Expression. PloS one, 2016, Volume: 11, Issue:6 Neutrophils are essential innate immune cells whose responses are crucial in the clearance of invading pathogens. Neutrophils can respond to infection by releasing neutrophil extracellular traps (NETs). NETs are formed of chromatin and specific granular proteins and are released after execution of a poorly characterized cell death pathway. Here, we show that NET formation induced by PMA or Candida albicans is independent of RNA polymerase II and III-mediated transcription as well as of protein synthesis. Thus, neutrophils contain all the factors required for NET formation when they emerge from the bone marrow as differentiated cells. Topics: Animals; Candida albicans; Chemokine CCL3; Cycloheximide; Dactinomycin; Extracellular Traps; Flavonoids; Gene Expression Regulation; Humans; Interleukin-8; Lipopolysaccharides; Male; Mice; Neutrophils; Piperidines; Primary Cell Culture; RNA Polymerase II; RNA Polymerase III; Salmonella typhimurium; Tetradecanoylphorbol Acetate	2016

Article

Year

Neutrophil Extracellular Trap Formation Is Independent of De Novo Gene Expression.

PloS one, 2016, Volume: 11, Issue:6

Neutrophils are essential innate immune cells whose responses are crucial in the clearance of invading pathogens. Neutrophils can respond to infection by releasing neutrophil extracellular traps (NETs). NETs are formed of chromatin and specific granular proteins and are released after execution of a poorly characterized cell death pathway. Here, we show that NET formation induced by PMA or Candida albicans is independent of RNA polymerase II and III-mediated transcription as well as of protein synthesis. Thus, neutrophils contain all the factors required for NET formation when they emerge from the bone marrow as differentiated cells.

Topics: Animals; Candida albicans; Chemokine CCL3; Cycloheximide; Dactinomycin; Extracellular Traps; Flavonoids; Gene Expression Regulation; Humans; Interleukin-8; Lipopolysaccharides; Male; Mice; Neutrophils; Piperidines; Primary Cell Culture; RNA Polymerase II; RNA Polymerase III; Salmonella typhimurium; Tetradecanoylphorbol Acetate

2016