Page last updated: 2024-09-03

interleukin-1beta (163-171) and indomethacin

interleukin-1beta (163-171) has been researched along with indomethacin in 4 studies

Compound Research Comparison

Studies (interleukin-1beta (163-171))	Trials (interleukin-1beta (163-171))	Recent Studies (post-2010) (interleukin-1beta (163-171))	Studies (indomethacin)	Trials (indomethacin)	Recent Studies (post-2010) (indomethacin)
192	3	74	29,527	1,838	3,396

Protein Interaction Comparison

Protein	Taxonomy	indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2	Macaca fascicularis (crab-eating macaque)	1000
Prostaglandin-H2 D-isomerase	Mus musculus (house mouse)	1.1
Multidrug resistance-associated protein 4	Homo sapiens (human)	5.8
Prostaglandin G/H synthase 1	Bos taurus (cattle)	0.9994
Prostaglandin G/H synthase 2	Bos taurus (cattle)	0.7764
Cytochrome c oxidase subunit 2	Homo sapiens (human)	0.34
Prostaglandin G/H synthase 1	Ovis aries (sheep)	0.5605
Neuronal acetylcholine receptor subunit alpha-4	Rattus norvegicus (Norway rat)	0.004
Interleukin-8	Homo sapiens (human)	0.05
Neuronal acetylcholine receptor subunit beta-2	Rattus norvegicus (Norway rat)	0.004
Aldo-keto reductase family 1 member B1	Homo sapiens (human)	6
Aldo-keto reductase family 1 member B1	Bos taurus (cattle)	5
Prostaglandin G/H synthase 1	Mus musculus (house mouse)	0.011
Prostaglandin G/H synthase 1	Homo sapiens (human)	0.4848
Sodium- and chloride-dependent GABA transporter 1	Rattus norvegicus (Norway rat)	0.2
Thromboxane-A synthase	Homo sapiens (human)	0.1
Indoleamine 2,3-dioxygenase 1	Mus musculus (house mouse)	0.082
Nitric oxide synthase, inducible	Mus musculus (house mouse)	4.5
Substance-P receptor	Cavia porcellus (domestic guinea pig)	5.7
Sodium- and chloride-dependent GABA transporter 2	Rattus norvegicus (Norway rat)	0.2
Sodium- and chloride-dependent GABA transporter 3	Rattus norvegicus (Norway rat)	0.2
Prostaglandin G/H synthase 2	Homo sapiens (human)	1.5128
Prostaglandin G/H synthase 2	Rattus norvegicus (Norway rat)	0.5504
Aldo-keto reductase family 1 member C3	Homo sapiens (human)	3.4486
Sodium- and chloride-dependent betaine transporter	Rattus norvegicus (Norway rat)	0.2
C-X-C chemokine receptor type 3	Homo sapiens (human)	0.05
Aldo-keto reductase family 1 member C2	Homo sapiens (human)	8.97
Prostaglandin G/H synthase 2	Ovis aries (sheep)	3.4647
Prostaglandin G/H synthase 2	Mus musculus (house mouse)	0.4233
Solute carrier family 22 member 6	Homo sapiens (human)	3
Sigma intracellular receptor 2	Rattus norvegicus (Norway rat)	0.49
Rho-associated protein kinase 2	Rattus norvegicus (Norway rat)	7.7
Prostaglandin G/H synthase 1	Rattus norvegicus (Norway rat)	0.5461
P2Y purinoceptor 12	Rattus norvegicus (Norway rat)	0.96

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (50.00)	18.7374
1990's	2 (50.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Boraschi, D; Dewhirst, FE; Lerner, UH; Ljunggren, O	1
Keenan, CM; Mugridge, KG; Parente, L; Wallace, JL	1
Endres, RO; Hasty, KA; Kang, AH; Lachman, LB; Poppleton, HM; Postlethwaite, AE; Seyer, JM; Smith, GN	1
Bartold, PM	1

Other Studies

4 other study(ies) available for interleukin-1beta (163-171) and indomethacin

Article	Year
Comparison of human interleukin-1 beta and its 163-171 peptide in bone resorption and the immune response. Cytokine, 1991, Volume: 3, Issue:2 Topics: Amino Acid Sequence; Animals; Antibody Formation; Bone and Bones; Bone Resorption; Bradykinin; Calcium; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Humans; Indomethacin; Interleukin-1; Interleukin-1beta; Kinetics; Mice; Mice, Inbred C3H; Molecular Sequence Data; Organ Culture Techniques; Peptide Fragments; Recombinant Proteins	1991
Reduction of the severity of experimental gastric and duodenal ulceration by interleukin-1 beta. European journal of pharmacology, 1990, Sep-21, Volume: 186, Issue:2-3 Topics: Animals; Cysteamine; Duodenal Ulcer; Ethanol; Indomethacin; Injections, Intraperitoneal; Interleukin-1; Interleukin-1beta; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Recombinant Proteins; Stomach Ulcer	1990
Stimulation of glycosaminoglycan synthesis in cultured human dermal fibroblasts by interleukin 1. Induction of hyaluronic acid synthesis by natural and recombinant interleukin 1s and synthetic interleukin 1 beta peptide 163-171. The Journal of clinical investigation, 1989, Volume: 83, Issue:2 Topics: Cells, Cultured; Dinoprostone; Fibroblasts; Glycosaminoglycans; Humans; Hyaluronic Acid; Indomethacin; Interleukin-1; Interleukin-1beta; Peptide Fragments; Protein Biosynthesis; Recombinant Proteins	1989
The effect of interleukin-1 beta on hyaluronic acid synthesized by adult human gingival fibroblasts in vitro. Journal of periodontal research, 1988, Volume: 23, Issue:2 Topics: Cell Division; Cycloheximide; Fibroblasts; Gingiva; Glucosamine; Humans; Hyaluronic Acid; Indomethacin; Interleukin-1; Interleukin-1beta; Peptide Fragments; Prostaglandin Antagonists; Recombinant Proteins; Tritium	1988