inositol and validamycin a

inositol has been researched along with validamycin a in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-19904 (5.63)18.7374
1990's4 (5.63)18.2507
2000's19 (26.76)29.6817
2010's35 (49.30)24.3611
2020's9 (12.68)2.80

Authors

AuthorsStudies
Kuhn, PJ; Robson, GD; Trinci, AP1
Jin, WZ; Rinehart, KL; Toyokuni, T1
Asano, N; Kameda, Y; Matsui, K; Ninomiya, K; Takeuchi, M1
Asano, N; Kameda, Y; Matsui, K; Teranishi, M1
Damm, B; de Graaf, PT; Goddijn, OJ; Krutwagen, RW; Pen, J; Poels, J; Ponstein, AS; van Dun, K; Verwoerd, TC; Voogd, E1
Cotter, DA; Temesvari, LA1
Amachi, T; Kayser, H; Knuesel, I; Murao, S; Shin, T1
Hsiao, YM; Lo, CC1
Dong, H; Floss, HG; Lee, S; Mahmud, T; Tornus, I1
Choi, YU; Mahmud, T; Xu, J1
El-Hawary, WF1
Floss, HG; Lee, S; Mahmud, T1
Cao, LL; Chen, SW; He, J; Ruan, LF; Yao, J; Yu, ZN1
Boboye, B1
García, NA; Herrera-Cervera, JA; Iribarne, C; Lluch, C; López, M1
Chen, X; Shen, Y; Zheng, Y1
Bai, L; Cao, E; Chen, S; Deng, Z; Floss, HG; Jian, X; Li, J; Li, L; Mahmud, T; Minagawa, K; Yu, Y; Zhou, X1
Shen, YC; Xue, YP; Zheng, YG1
Bai, L; Deng, Z; Floss, HG; Li, L; Mahmud, T; Minagawa, K; Xu, H; Yu, Y; Zhang, Y; Zhou, X1
Deng, Z; Jian, X; Pang, X; Yu, Y; Zhou, X1
Shen, YC; Wang, YS; Zheng, YG1
Bai, L; Deng, Z; Ito, T; Mahmud, T; Minagawa, K; Zhang, Y1
Chiara, JL; Davies, GJ; García, A; Gibson, RP; Gloster, TM; Roberts, S; Storch de Gracia, I; Warren, RA1
Kwon, HJ; Rajkarnikar, A; Singh, D; Suh, JW1
Bai, L; Deng, Z; Mahmud, T; Minagawa, K; Xu, H1
Lluch, C; López, M; Tejera, NA1
Bai, L; Deng, Z; Liao, Y; Wei, ZH; Zhong, JJ1
Gu, M; Wei, XD; Yao, RY; Zhao, B; Zhao, WJ1
Bai, L; Deng, Z; Wei, ZH; Zhong, JJ2
Best, M; Ferrieri, RA; Koenig, K; McDonald, K; Rogers, A; Schueller, M1
Bai, L; Deng, Z; Li, Z; Wu, H; Zhou, X1
Chang, YK; Hong, SK; Kim, CJ; Kim, SB; Li, H; Seo, YG; Su, H1
Bai, L; Huang, L; Ji, X; Li, L; Zhang, H; Zheng, L; Zhou, X1
Bai, L; Deng, Z; Wei, ZH; Wu, H; Zhong, JJ1
Ma, B; Tang, YJ; Zheng, X; Zhong, JJ; Zhou, WW1
Ji, S; Lee, J; Qian, GY; Si, YX; Wang, ZJ; Yang, JM; Yin, SJ1
Chen, X; Fan, Y; Jia, X; Shen, Y; Yu, Y1
Chen, C; Li, S; Peng, D; Wang, J; Zhou, M1
Boudreau, BA; Brown, DW; Busman, M; Kendra, DF; Larson, TM; McQuade, KL; Roberts, ES1
Asamizu, S; Codding, SJ; Karplus, PA; Kean, KM; Mahmud, T1
Kim, BG; Zhong, JJ; Zhou, TC1
Cheng, J; Fang, JC; Ge, LQ; Li, X; Lu, XL; Wu, JC; Zhu, ZF1
Han, C; Shen, Y; Tian, Z; Wang, C; Xu, D; Zhang, Z1
Zhong, JJ; Zhou, TC1
Bai, L; Kang, Q; Qu, S; Wang, L; Wu, H1
Amemiya, M; Honda, S; Ishida, SN; Kawakita, M; Oyama, F; Sakaguchi, M; Shimodaira, S; Sugahara, Y1
Ge, L; Jiang, Y; Li, L; Liu, Z; Song, Q; Stanley, D; Wu, J; Wu, Y; Xu, B; You, L1
Ge, LQ; Jiang, YP; Li, X; Lu, XL; Song, QS; Stanley, D; Wu, JC; Zhang, YX1
Ge, LQ; Jiang, YP; Li, L; Liu, ZY; Song, QS; Wu, JC; Wu, Y; Xu, B; You, LL1
Ding, J; Ge, LQ; Wu, JC; Wu, Y; Xu, B; You, LL1
Feng, J; Jiang, J; Li, W; Liu, Y; Zheng, X; Zhou, WW1
Azat, R; Feng, J; Jiang, J; Li, W; Liu, Y; Zheng, X; Zhou, WW1
Ding, J; Ge, LQ; Song, QS; Stanley, D; Wu, JC; Wu, Y; Xu, B; Yang, GQ; You, LL1
Chen, J; Dou, K; Li, Y; Wu, Q; Xia, H; Yu, C; Zhang, L1
Bai, L; Lu, C; Su, X; Wu, H1
Ding, J; Ge, LQ; Wu, JC; Wu, Y; Xu, B; Yang, GQ; You, LL1
Ge, LQ; Gu, HT; Huang, B; Jiang, YP; Liu, F; Wu, JC; Xia, T; Yang, GQ1
He, CN; Jiang, J; Shao, YL; Sun, YF; Tang, X; Tang, YJ; Zhou, WW1
Chen, Z; Fang, L; Li, H; Nie, Y; Wang, C; Zhang, H1
Ding, J; Ge, L; Liu, F; Song, Q; Stanley, D; Wu, J; Wu, Y; Xu, B; Yang, G; You, L1
Bai, L; Lu, C; Peng, Y1
Conway, MJ; Kalera, K; Marten, AD; Stothard, AI; Swarts, BM1
Ge, L; Huang, B; Song, QS; Stanley, D; Sun, K; Zhou, Z1
Chen, CX; Du, YM; Huang, YL; Lu, ZJ; Su, HN; Yi, L; Yu, HZ; Zhang, Q; Zhong, BL1
Bian, C; Duan, Y; Hou, Y; Song, X; Wang, J; Xiu, Q; Zhou, M1
Bian, H; Chen, Z; Dai, X; Guo, Z; Han, L; Li, H; Li, P; Li, W; Pu, E; Wang, C; Yong, Y; Zhang, X; Zhang, Y1
Argüelles, JC; García, MD1
Bian, C; Duan, Y; Tao, X; Wang, J; Xiu, Q; Zhou, M1
Dong, W; Li, T; Song, CY; Wu, WJ; Zhang, JZ1
Ahmad, S; Dong, Q; Duan, Z; Ge, L; Shi, J; Tan, Y; Tang, X; Wu, T; Xi, C; Zhu, H1

Reviews

2 review(s) available for inositol and validamycin a

ArticleYear
The biosynthesis of acarbose and validamycin.
    Chemical record (New York, N.Y.), 2001, Volume: 1, Issue:4

    Topics: Acarbose; Bacterial Proteins; Enzyme Inhibitors; Inositol; Molecular Structure; Sugar Phosphates

2001
Trehalase inhibition by validamycin A may be a promising target to design new fungicides and insecticides.
    Pest management science, 2021, Volume: 77, Issue:9

    Topics: Animals; Fungicides, Industrial; Humans; Inositol; Insecticides; Quality of Life; Trehalase; Trehalose

2021

Other Studies

69 other study(ies) available for inositol and validamycin a

ArticleYear
Effects of validamycin A on the morphology, growth and sporulation of Rhizoctonia cerealis, Fusarium culmorum and other fungi.
    Journal of general microbiology, 1988, Volume: 134, Issue:12

    Topics: Antifungal Agents; Drug Resistance, Microbial; Fungi; Fusarium; Inositol; Mitosporic Fungi; Rhizoctonia; Spores, Fungal

1988
Biosynthetic studies on validamycins. I. 1H and 13C NMR assignments of validamycin A.
    The Journal of antibiotics, 1987, Volume: 40, Issue:3

    Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Inositol; Magnetic Resonance Spectroscopy

1987
Microbial degradation of validamycin A by Flavobacterium saccharophilum. Enzymatic cleavage of C-N linkage in validoxylamine A.
    The Journal of antibiotics, 1984, Volume: 37, Issue:8

    Topics: Flavobacterium; Inositol; Magnetic Resonance Spectroscopy

1984
New cyclitols, degradation of validamycin A by Flavobacterium saccharophilum.
    The Journal of antibiotics, 1980, Volume: 33, Issue:12

    Topics: Flavobacterium; Inositol

1980
Inhibition of trehalase activity enhances trehalose accumulation in transgenic plants.
    Plant physiology, 1997, Volume: 113, Issue:1

    Topics: Cloning, Molecular; Escherichia coli; Glucosyltransferases; Inositol; Nicotiana; Phosphoric Monoester Hydrolases; Plants, Genetically Modified; Plants, Toxic; Solanum tuberosum; Trehalase; Trehalose

1997
Trehalase of Dictyostelium discoideum: inhibition by amino-containing analogs of trehalose and affinity purification.
    Biochimie, 1997, Volume: 79, Issue:4

    Topics: Animals; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Indolizines; Inositol; Sepharose; Sugar Alcohols; Trehalase

1997
Comparative studies of suidatrestin, a specific inhibitor of trehalases.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 1998, Volume: 120, Issue:4

    Topics: Animals; Carbohydrate Sequence; Diptera; Enzyme Inhibitors; Glycoside Hydrolase Inhibitors; In Vitro Techniques; Inositol; Insect Control; Insecticides; Kidney; Kinetics; Molecular Sequence Data; Saccharomyces cerevisiae; Spodoptera; Streptomyces; Swine; Trehalase

1998
Determination of the antibiotic fungicide validamycin A in formulated products by micellar electrokinetic chromatography.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:9

    Topics: Anti-Bacterial Agents; Carbohydrate Conformation; Carbohydrate Sequence; Chemistry, Pharmaceutical; Chromatography; Electrochemistry; Inositol; Micelles; Molecular Sequence Data

1999
Biosynthesis of the validamycins: identification of intermediates in the biosynthesis of validamycin A by Streptomyces hygroscopicus var. limoneus.
    Journal of the American Chemical Society, 2001, Mar-28, Volume: 123, Issue:12

    Topics: Anti-Bacterial Agents; Inositol; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Conformation; Molecular Structure; Streptomyces

2001
Synthesis of 5-epi-[6-(2)H(2)]valiolone and stereospecifically monodeuterated 5-epi-valiolones: exploring the steric course of 5-epi-valiolone dehydratase in validamycin A biosynthesis.
    The Journal of organic chemistry, 2001, Jul-27, Volume: 66, Issue:15

    Topics: Antifungal Agents; Carbohydrate Sequence; Hydro-Lyases; Indicators and Reagents; Inositol; Molecular Sequence Data; Nickel; Solvents; Streptomyces; Zinc

2001
Determination of lignocaine and amprolium in pharmaceutical formulations using AAS.
    Journal of pharmaceutical and biomedical analysis, 2002, Jan-01, Volume: 27, Issue:1-2

    Topics: Amprolium; Anesthetics, Local; Chemistry, Pharmaceutical; Coccidiostats; Hydrogen-Ion Concentration; Inositol; Lidocaine; Solubility; Spectrophotometry, Atomic

2002
Determination of the fungicide validamycin A by capillary zone electrophoresis with indirect UV detection.
    Journal of agricultural and food chemistry, 2003, Dec-17, Volume: 51, Issue:26

    Topics: Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Fungicides, Industrial; Hydrogen-Ion Concentration; Inositol; Quality Control

2003
Degradation of trehalose by rhizobia and characteristics of a trehalose-degrading enzyme isolated from Rhizobium species NGR234.
    Journal of applied microbiology, 2004, Volume: 97, Issue:2

    Topics: Culture Media; Disaccharides; Hot Temperature; Hydrogen-Ion Concentration; Inositol; Isoelectric Focusing; Molecular Weight; Rhizobium; Rhizobium etli; Rhizobium phaseoli; Rhizobium tropici; Trehalose

2004
Physiological implications of trehalase from Phaseolus vulgaris root nodules: partial purification and characterization.
    Plant physiology and biochemistry : PPB, 2005, Volume: 43, Issue:4

    Topics: Cations; Enzyme Activation; Enzyme Inhibitors; Enzyme Stability; Hydrogen-Ion Concentration; Inositol; Kinetics; Molecular Weight; Nitrogen Fixation; Phaseolus; Plant Roots; Substrate Specificity; Temperature; Trehalase

2005
Quantitative analysis of valienamine in the microbial degradation of validamycin A after derivatization with p-nitrofluorobenzene by reversed-phase high-performance liquid chromatography.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Sep-25, Volume: 824, Issue:1-2

    Topics: Bacteria; Biotransformation; Calibration; Chromatography, High Pressure Liquid; Culture Media, Conditioned; Cyclohexenes; Fluorobenzenes; Hexosamines; Inositol; Nitrobenzenes; Reproducibility of Results; Soil Microbiology; Temperature; Time Factors

2005
Gene cluster responsible for validamycin biosynthesis in Streptomyces hygroscopicus subsp. jinggangensis 5008.
    Applied and environmental microbiology, 2005, Volume: 71, Issue:9

    Topics: Amino Acid Sequence; Bacterial Proteins; Escherichia coli; Fungi; Gene Expression Regulation, Bacterial; Inositol; Microbial Sensitivity Tests; Molecular Sequence Data; Multigene Family; Oryza; Plant Diseases; Sequence Analysis, DNA; Streptomyces

2005
Preparation of trehalase inhibitor validoxylamine A by biocatalyzed hydrolysis of validamycin A with honeybee (Apis cerana Fabr.) beta-glucosidase.
    Applied biochemistry and biotechnology, 2005, Volume: 127, Issue:3

    Topics: Animals; Bees; beta-Glucosidase; Catalysis; Enzyme Inhibitors; Hydrolysis; Inositol; Insect Proteins; Trehalase

2005
Functional analysis of the validamycin biosynthetic gene cluster and engineered production of validoxylamine A.
    Chemistry & biology, 2006, Volume: 13, Issue:4

    Topics: Base Sequence; DNA, Bacterial; Gene Targeting; Genes, Bacterial; Genes, Regulator; Genetic Complementation Test; Genetic Engineering; Glycosylation; Glycosyltransferases; Inositol; Molecular Sequence Data; Molecular Structure; Multigene Family; Recombinant Proteins; Streptomyces; Streptomyces lividans

2006
Identification of genes necessary for jinggangmycin biosynthesis from Streptomyces hygroscopicus 10-22.
    Antonie van Leeuwenhoek, 2006, Volume: 90, Issue:1

    Topics: Base Sequence; Cloning, Molecular; Cosmids; Deoxyribonucleases, Type II Site-Specific; DNA Mutational Analysis; Genes, Bacterial; Inositol; Molecular Sequence Data; Molecular Structure; Physical Chromosome Mapping; Sequence Alignment; Sequence Deletion; Streptomyces

2006
Isolation and identification of a novel valienamine-producing bacterium.
    Journal of applied microbiology, 2007, Volume: 102, Issue:3

    Topics: China; Cyclohexenes; DNA, Bacterial; DNA, Ribosomal; Fermentation; Hexosamines; Inositol; Phenotype; Phylogeny; Soil Microbiology; Stenotrophomonas maltophilia; Triticum

2007
ValC, a new type of C7-Cyclitol kinase involved in the biosynthesis of the antifungal agent validamycin A.
    Chembiochem : a European journal of chemical biology, 2007, Apr-16, Volume: 8, Issue:6

    Topics: Amino Acid Sequence; Antifungal Agents; Carbohydrate Sequence; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cloning, Molecular; Cyclins; Cyclohexenes; Hexosamines; Inositol; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Phosphotransferases; Plasmids; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet; Streptomyces

2007
Molecular basis for trehalase inhibition revealed by the structure of trehalase in complex with potent inhibitors.
    Angewandte Chemie (International ed. in English), 2007, Volume: 46, Issue:22

    Topics: Catalysis; Colorimetry; Disaccharides; Enzyme Inhibitors; Hydrogen Bonding; Inositol; Protein Conformation; Trehalase

2007
Glucoamylase gene, vldI, is linked to validamycin biosynthesis in Streptomyces hygroscopicus var. limoneus, and vldADEFG confers validamycin production in Streptomyces lividans, revealing the role of VldE in glucose attachment.
    Gene, 2007, Jun-15, Volume: 395, Issue:1-2

    Topics: Base Sequence; Chromosome Mapping; DNA Primers; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Glucan 1,4-alpha-Glucosidase; Glucose; Inositol; Kinetics; Models, Biological; Multigene Family; Plasmids; Recombinant Proteins; Streptomyces; Streptomyces lividans

2007
Catalytic analysis of the validamycin glycosyltransferase (ValG) and enzymatic production of 4''-epi-validamycin A.
    Journal of natural products, 2008, Volume: 71, Issue:7

    Topics: Amino Acid Sequence; Antifungal Agents; Catalysis; Escherichia coli; Glycosyltransferases; Inositol; Microbial Sensitivity Tests; Molecular Structure; Rhizoctonia; Streptomyces; Substrate Specificity

2008
Validamycin A improves the response of Medicago truncatula plants to salt stress by inducing trehalose accumulation in the root nodules.
    Journal of plant physiology, 2009, Jul-15, Volume: 166, Issue:11

    Topics: Enzyme Activation; Gene Expression Regulation, Plant; Inositol; Medicago truncatula; Nitrogen Fixation; Root Nodules, Plant; Sodium Chloride; Stress, Physiological; Trehalase; Trehalose

2009
Effect of fermentation temperature on validamycin A production by Streptomyces hygroscopicus 5008.
    Journal of biotechnology, 2009, Jul-15, Volume: 142, Issue:3-4

    Topics: Cell Culture Techniques; Fermentation; Gene Dosage; Glucosephosphate Dehydrogenase; Glycosyltransferases; Inositol; Streptomyces; Temperature

2009
Simultaneous determination of substrate and product in the process of preparation of valienamine by capillary zone electrophoresis.
    Journal of separation science, 2010, Volume: 33, Issue:13

    Topics: Acarbose; Cyclohexenes; Electrophoresis, Capillary; Hexosamines; Inositol; Reproducibility of Results

2010
Enhanced production of validamycin A by H2O2-induced reactive oxygen species in fermentation of Streptomyces hygroscopicus 5008.
    Bioresource technology, 2011, Volume: 102, Issue:2

    Topics: Fermentation; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glucosephosphate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycosyltransferases; Hydrogen Peroxide; Inositol; Intracellular Space; Onium Compounds; Streptomyces; Time Factors; Transcription, Genetic

2011
Inhibition of trehalose breakdown increases new carbon partitioning into cellulosic biomass in Nicotiana tabacum.
    Carbohydrate research, 2011, Apr-01, Volume: 346, Issue:5

    Topics: Biomass; Carbon; Carbon Dioxide; Carbon Radioisotopes; Cellulose; Enzyme Activation; Inositol; Lignin; Nicotiana; Phenylalanine; Phenylalanine Ammonia-Lyase; Polysaccharides; Trehalase; Trehalose

2011
Over-expression of UDP-glucose pyrophosphorylase increases validamycin A but decreases validoxylamine A production in Streptomyces hygroscopicus var. jinggangensis 5008.
    Metabolic engineering, 2011, Volume: 13, Issue:6

    Topics: Fermentation; Glucosyltransferases; Glycosylation; Inositol; Streptomyces; Transcription, Genetic; Up-Regulation; Uridine Diphosphate Glucose; UTP-Glucose-1-Phosphate Uridylyltransferase

2011
Enhanced production of trehalose in Escherichia coli by homologous expression of otsBA in the presence of the trehalase inhibitor, validamycin A, at high osmolarity.
    Journal of bioscience and bioengineering, 2012, Volume: 113, Issue:2

    Topics: Enzyme Inhibitors; Escherichia coli; Glucosyltransferases; Inositol; Operon; Osmolar Concentration; Phosphoric Monoester Hydrolases; Trehalase; Trehalose

2012
Impact of nitrogen concentration on validamycin A production and related gene transcription in fermentation of Streptomyces hygroscopicus 5008.
    Bioprocess and biosystems engineering, 2012, Volume: 35, Issue:7

    Topics: Base Sequence; Culture Media; DNA Primers; Fermentation; Glucosephosphate Dehydrogenase; Inositol; Nitrogen; Real-Time Polymerase Chain Reaction; Streptomyces; Transcription, Genetic

2012
Structural and functional analysis of validoxylamine A 7'-phosphate synthase ValL involved in validamycin A biosynthesis.
    PloS one, 2012, Volume: 7, Issue:2

    Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Antifungal Agents; Catalysis; Catalytic Domain; Escherichia coli; Genetic Complementation Test; Glucosyltransferases; Inositol; Models, Chemical; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Multigene Family; Mutation; Open Reading Frames; Sequence Homology, Amino Acid; Streptomyces; Trehalose

2012
Temperature shift-induced reactive oxygen species enhanced validamycin A production in fermentation of Streptomyces hygroscopicus 5008.
    Bioprocess and biosystems engineering, 2012, Volume: 35, Issue:8

    Topics: Hot Temperature; Inositol; Reactive Oxygen Species; Streptomyces; Transcription, Genetic

2012
Enhancement of validamycin A production by addition of ethanol in fermentation of Streptomyces hygroscopicus 5008.
    Bioresource technology, 2012, Volume: 114

    Topics: Dose-Response Relationship, Drug; Ethanol; Inositol; Reactive Oxygen Species; Streptomyces

2012
The effect of validamycin A on tyrosinase: inhibition kinetics and computational simulation.
    International journal of biological macromolecules, 2013, Volume: 55

    Topics: Binding Sites; Enzyme Activation; Enzyme Inhibitors; Inositol; Kinetics; Molecular Docking Simulation; Molecular Dynamics Simulation; Monophenol Monooxygenase; Protein Binding; Protein Conformation

2013
Cloning, expression and medium optimization of validamycin glycosyltransferase from Streptomyces hygroscopicus var. jinggangensis for the biotransformation of validoxylamine A to produce validamycin A using free resting cells.
    Bioresource technology, 2013, Volume: 131

    Topics: Biotransformation; Cloning, Molecular; Culture Media; Escherichia coli; Glycosyltransferases; Inositol; Recombinant Proteins; Species Specificity; Streptomyces

2013
Integrated biological and chemical control of rice sheath blight by Bacillus subtilis NJ-18 and jinggangmycin.
    Pest management science, 2014, Volume: 70, Issue:2

    Topics: Bacillus subtilis; Biological Control Agents; Environment, Controlled; Fungicides, Industrial; Inositol; Oryza; Plant Diseases; Rhizoctonia

2014
Impact of temperature stress and validamycin A on compatible solutes and fumonisin production in F. verticillioides: role of trehalose-6-phosphate synthase.
    Fungal genetics and biology : FG & B, 2013, Volume: 57

    Topics: Animals; Fumonisins; Fusarium; Glucosyltransferases; Humans; Inositol; Polymers; Stress, Physiological; Temperature; Trehalose; Zea mays

2013
Structure of a sedoheptulose 7-phosphate cyclase: ValA from Streptomyces hygroscopicus.
    Biochemistry, 2014, Jul-08, Volume: 53, Issue:26

    Topics: Bacterial Proteins; Crystallography, X-Ray; Inositol; Intramolecular Lyases; Protein Structure, Secondary; Protein Structure, Tertiary; Streptomyces; Sugar Phosphates

2014
Enhanced production of validamycin A in Streptomyces hygroscopicus 5008 by engineering validamycin biosynthetic gene cluster.
    Applied microbiology and biotechnology, 2014, Volume: 98, Issue:18

    Topics: Inositol; Multigene Family; Streptomyces

2014
Comparisons of topical and spray applications of two pesticides, triazophos and jinggangmycin, on the protein content in the ovaries and fat bodies of the brown planthopper Nilaparvata lugens Stål (Hemiptera:Delphacidae).
    Pesticide biochemistry and physiology, 2014, Volume: 114

    Topics: Animals; Fat Body; Female; Fungicides, Industrial; Hemiptera; Inositol; Insect Proteins; Insecticides; Organothiophosphates; Ovary; Triazoles

2014
Determination of validamycin A in agricultural food samples by solid-phase extraction combined with liquid chromatography-atmospheric pressure chemical ionisation-tandem mass spectrometry.
    Food chemistry, 2015, Feb-15, Volume: 169

    Topics: Atmospheric Pressure; Chromatography, High Pressure Liquid; Crops, Agricultural; Inositol; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry

2015
Production of validamycin A from hemicellulose hydrolysate by Streptomyces hygroscopicus 5008.
    Bioresource technology, 2015, Volume: 175

    Topics: Arabinose; Carbon; Fermentation; Glucose; Hydrolysis; Industrial Microbiology; Inositol; Polysaccharides; Streptomyces; Xylose; Zea mays

2015
Positive and negative regulation of GlnR in validamycin A biosynthesis by binding to different loci in promoter region.
    Applied microbiology and biotechnology, 2015, Volume: 99, Issue:11

    Topics: Binding Sites; DNA Footprinting; DNA Mutational Analysis; DNA, Bacterial; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Inositol; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Streptomyces; Trans-Activators

2015
Identification of GH15 Family Thermophilic Archaeal Trehalases That Function within a Narrow Acidic-pH Range.
    Applied and environmental microbiology, 2015, Volume: 81, Issue:15

    Topics: Amino Acid Sequence; Amino Acid Substitution; Catalytic Domain; Cluster Analysis; DNA, Archaeal; Enzyme Inhibitors; Enzyme Stability; Escherichia coli; Gene Expression; Hydrogen-Ion Concentration; Inositol; Kinetics; Molecular Sequence Data; Molecular Weight; Mutant Proteins; Phylogeny; Recombinant Proteins; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology; Temperature; Thermoplasma; Trehalase; Trehalose

2015
Jinggangmycin increases fecundity of the brown planthopper, Nilaparvata lugens (Stål) via fatty acid synthase gene expression.
    Journal of proteomics, 2016, Jan-01, Volume: 130

    Topics: Animals; Antifungal Agents; Body Weight; Fat Body; Fatty Acid Synthases; Female; Fertility; Gene Expression Profiling; Gene Expression Regulation; Gene Silencing; Hemiptera; Inositol; Insect Proteins; Lipids; Oryza; Ovary; RNA Interference; RNA, Double-Stranded

2016
RNAi knockdown of acetyl-CoA carboxylase gene eliminates jinggangmycin-enhanced reproduction and population growth in the brown planthopper, Nilaparvata lugens.
    Scientific reports, 2015, Oct-20, Volume: 5

    Topics: Acetyl-CoA Carboxylase; Animals; Cluster Analysis; Gene Expression Profiling; Gene Knockdown Techniques; Gene Silencing; Hemiptera; Inositol; Reproducibility of Results; Reproduction; RNA Interference; Transcriptome

2015
Adipose triglyceride lipase (Atgl) mediates the antibiotic jinggangmycin-stimulated reproduction in the brown planthopper, Nilaparvata lugens Stål.
    Scientific reports, 2016, Jan-07, Volume: 6

    Topics: Animals; Anti-Bacterial Agents; Body Weight; Fat Body; Female; Glycerol; Hemiptera; Inositol; Insect Proteins; Lipase; Male; Ovary; Reproduction; Transcriptome; Up-Regulation

2016
Transmission Electron Microscopy (TEM) Observations of Female Oocytes From Nilaparvata lugens (Hemiptera: Delphacidae): Antibiotic Jinggangmycin (JGM)-Induced Stimulation of Reproduction and Associated Changes in Hormone Levels.
    Journal of economic entomology, 2016, Volume: 109, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Female; Hemiptera; Inositol; Insect Hormones; Microscopy, Electron, Transmission; Oocytes; Reproduction

2016
Novel spectrophotometric approach for determination of validamycin A in fermentation of Streptomyces hygroscopicus.
    Journal of bioscience and bioengineering, 2016, Volume: 122, Issue:6

    Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Fermentation; Inositol; Limit of Detection; Reproducibility of Results; Spectrophotometry; Streptomyces

2016
Significance of oxygen carriers and role of liquid paraffin in improving validamycin A production.
    Journal of industrial microbiology & biotechnology, 2016, Volume: 43, Issue:10

    Topics: Anti-Bacterial Agents; Fermentation; Glucosephosphate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Inositol; Mineral Oil; Oxidative Stress; Oxygen; Streptomyces

2016
Driving Pest Insect Populations: Agricultural Chemicals Lead to an Adaptive Syndrome in Nilaparvata Lugens Stål (Hemiptera: Delphacidae).
    Scientific reports, 2016, 11-23, Volume: 6

    Topics: Acetyl-CoA Carboxylase; Agrochemicals; Animals; China; Climate Change; Female; Fertility; Fungicides, Industrial; Global Warming; Hemiptera; HSP70 Heat-Shock Proteins; Humans; Inositol; Insect Proteins; Insecticides; Oryza; Ovary; Reproduction; Rhizoctonia; RNA Interference

2016
Omics for understanding synergistic action of validamycin A and Trichoderma asperellum GDFS1009 against maize sheath blight pathogen.
    Scientific reports, 2017, 01-06, Volume: 7

    Topics: Anti-Bacterial Agents; Inositol; Plant Diseases; Rhizoctonia; Trichoderma; Zea mays

2017
Elimination of indigenous linear plasmids in Streptomyces hygroscopicus var. jinggangensis and Streptomyces sp. FR008 to increase validamycin A and candicidin productivities.
    Applied microbiology and biotechnology, 2017, Volume: 101, Issue:10

    Topics: Bacterial Proteins; Candicidin; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Inositol; Multigene Family; Mutation; Plasmids; Promoter Regions, Genetic; Secondary Metabolism; Streptomyces

2017
Jinggangmycin-suppressed reproduction in the small brown planthopper (SBPH), Laodelphax striatellus (Fallen), is mediated by glucose dehydrogenase (GDH).
    Pesticide biochemistry and physiology, 2017, Volume: 139

    Topics: Animals; Female; Fungicides, Industrial; Glucose 1-Dehydrogenase; Hemiptera; Inositol; Oviposition; Reproduction

2017
Carboxylesterase Precursor (EST-1) Mediated the Fungicide Jinggangmycin-Suppressed Reproduction of Sogatella furcifera (Hemiptera: Delphacidae).
    Journal of economic entomology, 2017, 10-01, Volume: 110, Issue:5

    Topics: Amino Acid Sequence; Animals; Base Sequence; Body Weight; Carbohydrate Metabolism; Carboxylesterase; Female; Hemiptera; Inositol; Insect Proteins; Ovary; Reproduction; RNA Interference; Sequence Analysis, DNA

2017
Alkaline pH shock enhanced production of validamycin A in fermentation of Streptomyces hygroscopicus.
    Bioresource technology, 2018, Volume: 249

    Topics: Carbon; Fermentation; Inositol; Streptomyces

2018
Simultaneous determination of kasugamycin and validamycin-A residues in cereals by consecutive solid-phase extraction combined with liquid chromatography-tandem mass spectrometry.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2018, Volume: 35, Issue:3

    Topics: Agriculture; Aminoglycosides; Anti-Bacterial Agents; Carbohydrate Conformation; Chromatography, High Pressure Liquid; Edible Grain; Food Contamination; Hydrophobic and Hydrophilic Interactions; Inositol; Solid Phase Extraction; Tandem Mass Spectrometry

2018
Two Fungicides Alter Reproduction of the Small Brown Planthopper Laodelphax striatellus by Influencing Gene and Protein Expression.
    Journal of proteome research, 2018, 03-02, Volume: 17, Issue:3

    Topics: Animals; Benzimidazoles; Carbamates; Female; Fertility; Fungicides, Industrial; Gene Expression Regulation; Gene Ontology; Hemiptera; Hydroxysteroid Dehydrogenases; Inositol; Insect Proteins; Lipid Metabolism; Long-Chain-3-Hydroxyacyl-CoA Dehydrogenase; Molecular Sequence Annotation; Oryza; Ovary; Oviposition; Proteome; Reproduction; RNA, Small Interfering; Zygote

2018
[Effects of pigment gene deletions on validamycin A production in Streptomyces hygroscopicus var. jinggangensis].
    Wei sheng wu xue bao = Acta microbiologica Sinica, 2016, Nov-04, Volume: 56, Issue:11

    Topics: Bacterial Proteins; Biosynthetic Pathways; Fermentation; Gene Deletion; Gene Expression Regulation, Bacterial; Inositol; Melanins; Streptomyces

2016
Validamycin A Delays Development and Prevents Flight in Aedes aegypti (Diptera: Culicidae).
    Journal of medical entomology, 2020, 07-04, Volume: 57, Issue:4

    Topics: Aedes; Animals; Female; Flight, Animal; Inositol; Male; Mosquito Vectors; Sex Ratio; Trehalase; Trehalose

2020
The antibiotic jinggangmycin increases brown planthopper (BPH) fecundity by enhancing rice plant sugar concentrations and BPH insulin-like signaling.
    Chemosphere, 2020, Volume: 249

    Topics: Animals; Anti-Bacterial Agents; Fertility; Hemiptera; Inositol; Insulin; Oryza; RNA, Double-Stranded; Sugars

2020
Inhibition of trehalase affects the trehalose and chitin metabolism pathways in Diaphorina citri (Hemiptera: Psyllidae).
    Insect science, 2021, Volume: 28, Issue:3

    Topics: Animals; Chitin; Gene Expression Regulation; Genes, Insect; Hemiptera; Inositol; Pest Control; RNA Interference; Trehalase; Trehalose

2021
Validamycin A Induces Broad-Spectrum Resistance Involving Salicylic Acid and Jasmonic Acid/Ethylene Signaling Pathways.
    Molecular plant-microbe interactions : MPMI, 2020, Volume: 33, Issue:12

    Topics: Arabidopsis; Arabidopsis Proteins; Botrytis; Cyclopentanes; Disease Resistance; Ethylenes; Fusarium; Inositol; Oxylipins; Plant Diseases; Salicylic Acid; Signal Transduction

2020
HLB-MCX-Based Solid-Phase Extraction Combined with Liquid Chromatography-Tandem Mass Spectrometry for the Simultaneous Determination of Four Agricultural Antibiotics (Kasugamycin, Validamycin A, Ningnanmycin, and Polyoxin B) Residues in Plant-Origin Foods
    Journal of agricultural and food chemistry, 2020, Nov-25, Volume: 68, Issue:47

    Topics: Aminoglycosides; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cytidine; Inositol; Pyrimidine Nucleosides; Solid Phase Extraction; Tandem Mass Spectrometry

2020
Mechanism of validamycin A inhibiting DON biosynthesis and synergizing with DMI fungicides against Fusarium graminearum.
    Molecular plant pathology, 2021, Volume: 22, Issue:7

    Topics: Cytochrome P450 Family 51; Drug Synergism; Fungal Proteins; Fungicides, Industrial; Fusarium; Inositol; Plant Diseases; Pyruvate Kinase; Trehalase; Trichothecenes; Triticum; Virulence

2021
Jinggangmycin stimulates reproduction and increases CHCs-dependent desiccation tolerance in Drosophila melanogaster.
    Pesticide biochemistry and physiology, 2023, Volume: 194

    Topics: Animals; Desiccation; Drosophila melanogaster; Female; Inositol; Reproduction

2023
The Jinggangmycin-induced Mthl2 gene regulates the development and stress resistance in Nilaparvata lugens Stål (Hemiptera: Delphacidae).
    Pesticide biochemistry and physiology, 2023, Volume: 196

    Topics: Animals; Female; Hemiptera; Inositol; Male; Oryza; Ovary; Transcriptome

2023