inositol has been researched along with inositol 1,4,5-trisphosphate in 162 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (33.33) | 18.7374 |
| 1990's | 94 (58.02) | 18.2507 |
| 2000's | 6 (3.70) | 29.6817 |
| 2010's | 6 (3.70) | 24.3611 |
| 2020's | 2 (1.23) | 2.80 |
| Authors | Studies |
|---|---|
| Irvine, RF; Letcher, AJ; Musgrave, A; Stephens, LR | 1 |
| Greenberg, L; Shayman, JA; Urbanes, AQ | 1 |
| Hildebrandt, JP; Shuttleworth, TJ | 1 |
| Cubitt, AB; Firtel, RA | 1 |
| Chung, HC; Fleming, N | 1 |
| Anderson, K; Woodcock, EA | 1 |
| Challiss, RA; Jenkinson, S; Nahorski, SR | 1 |
| Belyavskyi, M; Sauer, HW | 1 |
| Berridge, MJ; Bootman, MD; Taylor, CW | 1 |
| Alouf, JE; Berthou, L; Corvaia, N; Geoffroy, C; Launay, JM; Mutel, V | 1 |
| Dixon, JF; Hokin, LE; Lee, CH; Los, GV | 1 |
| Buller, RM; Hughes, PJ; Oliver, KG; Palumbo, GJ; Putney, JW | 1 |
| Currier, RD; Desaiah, D; Subramony, SH; Vig, PJ | 1 |
| Fullerton, M; Kuraja, IJ; Tanner, JK; Woodcock, EA | 1 |
| Docampo, R; Moreno, SN; Vercesi, AE | 1 |
| Catt, KJ; Iida, T; Ji, H; Sandberg, K | 1 |
| Baten, A; Lalwani, ND; Shamsuddin, AM | 1 |
| Kowatch, MA; Roth, GS | 1 |
| Bominaar, AA; van der Kaay, J; van Haastert, PJ | 1 |
| Rehn, M; Tayag, A; Tio, D; Warburton, D | 1 |
| MacNulty, EE; Palmer, S; Plevin, R; Wakelam, MJ | 1 |
| Braquet, P; Her, E; Reiss, N; Zor, U | 1 |
| Lapetina, EG; Lazarowski, ER; Nolan, RD; Oberdisse, E; Winegar, DA | 1 |
| Hertelendy, F; Molnár, M | 1 |
| Chen, JK; Orlando, JA; Pontbriant, CM | 1 |
| Bird, GJ; Horstman, DA; Obie, J; Oliver, KG; Putney, JW | 1 |
| Azim, S; Baron, CB; Pompeo, JN | 1 |
| Abe, A; Deshmukh, GD; Mahdiyoun, S; Radin, NS; Shayman, JA | 1 |
| Fruen, BR; Lester, BR | 1 |
| Hughes, AR; Ignar-Trowbridge, DM; Korach, KS; McLachlan, JA; Putney, JW | 1 |
| Challiss, RA; Lambert, DG; Nahorski, SR | 1 |
| Roewer, N; Rum, U; Schmitz, W; Scholz, H; Scholz, J; Schulte am Esch, J | 1 |
| Hu, TS; Li, WY; Qin, M; Tang, L; Zhou, Q | 1 |
| Benjamin, TL; Gorga, FR; Riney, CE | 1 |
| Battle-Tracy, KM; Owen, NE; Zaragoza, R | 1 |
| McIntosh, JE; McIntosh, RP | 1 |
| Crea, AE; Grandordy, BM; Krilis, S; Lacroix, H; Lee, TH; Mavoungou, E; Spur, BW | 1 |
| Chien, WW; Clusin, WT; Mohabir, R | 1 |
| Shayman, JA; Wu, D | 1 |
| Abdel-Latif, AA; Tachado, SD; Yousufzai, SY | 1 |
| Coronado, R; Potter, BV; Valdivia, C; Valdivia, HH | 1 |
| De Jonge, HR; Ploemacher, MC; Vaandrager, AB | 1 |
| Hansen, CA; Siemens, IR; Williamson, JR | 1 |
| Sanborn, BB; Schneider, AS | 1 |
| Heal, DJ; Kendall, DA; Whitworth, P | 1 |
| Ammon, HP; Klosa, M; Verspohl, EJ | 1 |
| Cooke, AM; Nahorski, SR; Potter, BV; Wojcikiewicz, RJ | 1 |
| Bazer, FW; Davis, M; Mirando, MA; Ott, TL; Vallet, JL | 1 |
| Shuttleworth, TJ | 1 |
| Menniti, FS; Nogimori, K; Obie, JF; Oliver, KG; Putney, JW; Shears, SB | 1 |
| Berrie, CP; Irvine, RF; Stephens, LR | 1 |
| Dartt, DA; Dicker, DM; Hodges, RR; Kjeldsen, IM; Murphy, SA; Ronco, LV | 1 |
| Zhang, L | 1 |
| Houlihan, MJ; Powers, RE; Saluja, AK; Steer, ML | 1 |
| Smith, JB | 1 |
| Holub, BJ | 1 |
| Isseroff, R; Martinez, D; Tang, W; Ziboh, VA | 1 |
| Aaronson, SA; Fleming, TP; Lopez-Barahona, M; Molloy, CJ; Moscat, J | 1 |
| Festa, F; Pfeilschifter, J; Thüring, B | 1 |
| McCarren, M; Miller, RJ; Potter, BV | 1 |
| Cooke, AM; Nahorski, SR; Potter, BV | 1 |
| Erikson, RL; Martins, TJ; Sugimoto, Y | 1 |
| De Vries, MJ; Erneux, C; Penning, LC; Roovers, E; Van der Kaay, J; Van Haastert, PJ; Van Lookeren Campagne, MM | 1 |
| Downes, CP | 1 |
| Blackmore, PF; Exton, JH | 1 |
| Abdel-Latif, AA; Honkanen, RE | 1 |
| Printz, MP; Rasmussen, K | 1 |
| Downes, CP; Hawkins, PT; Stephens, LR | 1 |
| Hughes, AR; Putney, JW; Takemura, H; Thastrup, O | 1 |
| Burhol, PG; Florholmen, J; Malm, D; Vonen, B | 1 |
| Knauf, PA; Kozody, DJ; Restrepo, D | 1 |
| Logan, SD; Stephens, LR | 1 |
| Berridge, MJ; Cooke, AM; Potter, BV; Taylor, CW | 1 |
| Rink, TJ | 1 |
| Fujiwara, Y; Fukunaga, M; Kamada, T; Ochi, S; Orita, Y; Shin, SH; Tagawa, K; Takama, T; Wada, A | 1 |
| Nånberg, E; Nedergaard, J | 1 |
| McLeod, JK; Smith, AI; White, LB; Woodcock, EA | 1 |
| Hu, TS; Li, WY; Qin, M; Zhou, Q | 1 |
| Adamo, S; Conti, M; Monaco, L | 1 |
| Litosch, I; Pijuan, V | 1 |
| Cooke, AM; Nahorski, SR; Potter, BV; Willcocks, AL | 1 |
| Fullerton, M; Lang, R; Smith, AI; von Harsdorf, R; Woodcock, EA | 1 |
| Biden, TJ; Peter-Riesch, B; Schlegel, W; Wollheim, CB | 1 |
| Brown, JH; Masters, SB; Quinn, MT | 1 |
| Abdel-Latif, AA; Akhtar, RA | 1 |
| Davis, JS; Farese, RV; West, LA | 1 |
| Drummond, AH | 1 |
| Bonvini, E; Farrar, WL; Hoffman, T; Ponzoni, M; Ruscetti, FW | 1 |
| Calderwood, SK; Hahn, GM; Stevenson, MA | 1 |
| Bjøro, T; Haug, E; Ostberg, BC; Torjesen, PA | 1 |
| Minke, B; Selinger, Z | 1 |
| Dean, NM; Moyer, JD | 1 |
| Kinlough-Rathbone, RL; Mustard, JF; Packham, MA; Rand, ML; Vickers, JD | 1 |
| Best, L; Tomlinson, S; Tuersley, MD | 1 |
| Cooke, AM; Gigg, R; Nahorski, SR; Potter, BV; Strupish, J | 1 |
| Alonso, T; Marvizon, JC; Morgan, RO; Santos, E; Zarbl, H | 1 |
| Berridge, MJ; Brown, KD; Cooke, AM; Potter, BV; Taylor, CW | 1 |
| Bradford, PG; Rubin, RP | 1 |
| McKinney, JS; Putney, JW; Tennes, KA | 1 |
| Davis, JS; Farese, RV; Weakland, LL; West, LA | 1 |
| Dillon, SB; Murray, JJ; Snyderman, R; Verghese, MW | 1 |
| Andersson, LC; Eloranta, T; Mustelin, T; Pösö, H; Ståhls, A | 1 |
| McDaniel, ML; Turk, J; Wolf, BA | 1 |
| Catt, KJ; Chang, JP; Morgan, RO | 1 |
| Berridge, MJ; Brown, KD; Heslop, JP; Irvine, RF | 1 |
| Berridge, MJ | 1 |
| Downes, CP; Irvine, RF; Lander, DJ; Letcher, AJ | 1 |
| Martinez, RP; Raffa, RB | 1 |
| Melvin, JE; Zhang, GH | 1 |
| Barańska, J; Czarny, M; Rojek, A; Wiktorek, M | 1 |
| Van der Kaay, J; Van Haastert, PJ | 1 |
| Brave, SR; Gibson, A; McFadzean, I; Mirzazadeh, S; Tucker, JF; Wayman, C | 1 |
| Ahmed, A; Plevin, R; Sage, SO; Sharkey, AM; Shoaibi, MA; Smith, SK | 1 |
| Desai, T; Gigg, J; Gigg, R; Martín-Zamora, E | 1 |
| Denborough, MA; Foster, PS; Hansbro, PM; Hogan, SP; O'Brien, R; Ozaki, S; Potter, BV | 1 |
| Atack, JR; Fletcher, SR; McKernan, R; Prior, AM; Quirk, K; Ragan, CI | 1 |
| Baines, D; Downer, RG | 1 |
| Géraud, G; Kubiak, J; Lefèvre, B; Maro, B; Pesty, A; Tesarik, J | 1 |
| Brooker, G; Mattie, M; Spiegel, S | 1 |
| Hinson, JP; Kapas, S; Vinson, GP | 1 |
| Ling, L; Ozaki, S | 1 |
| Lilford, K; Tomera, JF | 2 |
| Atack, JR; Griffith, D; Prior, AM; Ragan, CI | 1 |
| Behar, J; Biancani, P; De Petris, G; Harnett, KM; Yu, P | 1 |
| Lakin-Thomas, PL | 1 |
| Aubry, JP; Bacon, KB; Camp, RD; Quinn, DG | 1 |
| Agranoff, BW; Heacock, AM; Seguin, EB | 1 |
| Allan, CJ; Exton, JH | 1 |
| Kukulka, SP; Lilford, K; Tomera, JF | 1 |
| Claro, E; Fain, JN; Picatoste, F | 1 |
| Irvine, RF; Wreggett, KA | 1 |
| Bercier, JG; Frazier, LW | 1 |
| Van der Kaay, J; Van Haastert, PJ; Wesseling, J | 1 |
| Suzuki, S; Takahashi, H; Yamaguchi, M | 1 |
| Eggo, MC; Hunt, P; Kirk, CJ; Michell, RH; Sheppard, MC; Singh, J | 1 |
| Gielbert, ML; Van den Broek, AT; Van der Horst, DJ; Van Marrewijk, WJ | 1 |
| Davey, J; Hirata, M; Hughes, PJ; Michell, RH; Ongusaha, PP | 1 |
| Huang, HM; Jang, TH; Lin, LB; Ou, HC; Sun, SH | 1 |
| Becchetti, A; Whitaker, M | 1 |
| Kendall, DA; Marsden, CA; Roberts, RE | 1 |
| Eriksson, LC; Nilsson, H; Torndal, UB | 1 |
| del Río, E; Downes, CP; Nicholls, DG; Shinomura, T; van der Kaay, J | 1 |
| Marino, M; Pallottini, V; Trentalance, A | 1 |
| Chakrabartty, A; Franklin, T; Fraser, PE; McLaurin, J | 1 |
| Davey, J; Hughes, PJ; Michell, RH; Ongusaha, PP | 1 |
| Cachero, MT; González, C; Rigual, R; Rocher, A | 1 |
| Müller-Esterl, W; Nahorski, SR; Willars, GB | 1 |
| Boss, WF; Heilmann, I; Perera, IY; Persson, S; Stevenson, JM | 1 |
| Gross, KW; Hajduczok, G; Ryan, MJ | 1 |
| Dozol, H; Potter, BV; Riley, AM; Spiess, B | 1 |
| Choe, CU; Ehrlich, BE; Grant, W; Harrison, KD | 1 |
| Nurrish, SJ; Saiardi, A; Tokuoka, SM | 1 |
| Chan, AW; Chung, SK; Dai, Z; Kung, AW; Lau, KS; Miao, D | 1 |
| Cockcroft, S; Skippen, A; Swigart, P | 1 |
| Gillaspy, GE | 2 |
| Compton, BJ; Larsen, DS; Lee, AM; Painter, GF | 1 |
| Bartlett, PJ; Gaspers, LD; Metzger, W; Thomas, AP | 1 |
| Agam, G; Berry, GT; Bersudsky, Y; Einat, H; Kara, NZ; Moechars, D; Rapoport, S; Sade, Y; Toker, L | 1 |
| Arige, V; Knebel, TR; Malik, S; Terry, LE; Wagner Ii, LE; Yule, DI | 1 |
| Chen, YS; Van Petegem, F | 1 |
8 review(s) available for inositol and inositol 1,4,5-trisphosphate
| Article | Year |
|---|---|
Disruption of phosphoinositide signalling by lithium.
Topics: Animals; Cerebral Cortex; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Phosphatidylinositols; Signal Transduction | 1992 |
Dynamics and function of the inositolcycle in Dictyostelium discoideum.
Topics: Cell Membrane Permeability; Cyclic AMP; Dictyostelium; Guanosine 5'-O-(3-Thiotriphosphate); Inositol; Inositol 1,4,5-Trisphosphate; Phosphorylation | 1991 |
Angiotensin-receptor signaling in cultured vascular smooth muscle cells.
Topics: Amiloride; Angiotensin II; Animals; Biological Transport; Calcium; Cells, Cultured; Chlorides; Cytosol; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Membranes; Ion Channels; Ligands; Lipids; Muscle, Smooth, Vascular; Nucleotides, Cyclic; Potassium; Receptors, Angiotensin; Receptors, Cell Surface; Sodium; Stimulation, Chemical | 1986 |
Metabolism and function of myo-inositol and inositol phospholipids.
Topics: Absorption; Animals; Arachidonic Acid; Arachidonic Acids; Biological Transport, Active; Carrier Proteins; Cell Membrane; Diabetes Mellitus; Diet; Digestion; Diglycerides; Female; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kidney Diseases; Liver; Lung; Male; Phosphatidic Acids; Phosphatidylinositols; Phospholipids; Pregnancy; Tissue Distribution; Triglycerides; Whipple Disease | 1986 |
[The role of inositol cycle in signal transduction in the cell nucleus].
Topics: Animals; Calcium; Cell Nucleus; Diglycerides; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Phosphoric Diester Hydrolases; Protein Kinase C; Signal Transduction | 1995 |
Inositol signaling and plant growth.
Topics: Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Phosphatidylinositols; Plant Development; Signal Transduction; Stereoisomerism | 2000 |
The cellular language of myo-inositol signaling.
Topics: Cell Membrane; Inositol; Inositol 1,4,5-Trisphosphate; Plant Cells; Second Messenger Systems; Signal Transduction | 2011 |
The role of phosphoinositides and inositol phosphates in plant cell signaling.
Topics: Diglycerides; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Phosphatidylinositols; Phytic Acid; Plant Cells; Signal Transduction; Type C Phospholipases | 2013 |
154 other study(ies) available for inositol and inositol 1,4,5-trisphosphate
| Article | Year |
|---|---|
Inositol polyphosphate metabolism and inositol lipids in a green alga, Chlamydomonas eugametos.
Topics: Animals; Chlamydomonas; Chromatography, High Pressure Liquid; Erythrocytes; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Phosphorylation; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Turkeys | 1992 |
Unimpaired formation of hormone-stimulated inositol trisphosphate in human mesangial cells under hyperglycemic conditions.
Topics: Bradykinin; Calcium; CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase; Cell Line; Chromatography; Glomerular Mesangium; Glucose; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Membrane Proteins; Phosphatidylinositols; Phosphotransferases; Transferases (Other Substituted Phosphate Groups); Vasopressins | 1992 |
Calcium-sensitivity of inositol 1,4,5-trisphosphate metabolism in exocrine cells from the avian salt gland.
Topics: Animals; Calcium; Ducks; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Salt Gland; Signal Transduction; Tritium | 1992 |
Characterization of phospholipase activity in Dictyostelium discoideum. Identification of a Ca(2+)-dependent polyphosphoinositide-specific phospholipase C.
Topics: Animals; Calcium; Cell Membrane; Chromatography, High Pressure Liquid; Dictyostelium; Guanosine 5'-O-(3-Thiotriphosphate); Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Membrane Lipids; Palmitic Acid; Palmitic Acids; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases | 1992 |
Arachidonic acid regulates the phosphoinositide signal transduction pathway in submandibular acinar cells.
Topics: Animals; Arachidonic Acid; Carbachol; Cells, Cultured; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Leukotrienes; Male; Mucins; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Prostaglandins; Protein Kinase C; Rats; Rats, Inbred Strains; Signal Transduction; Submandibular Gland | 1992 |
Isolation of adult cardiomyocytes initiates a return of inositol trisphosphate phosphorylating activity.
Topics: Animals; Cells, Cultured; Chlorides; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Lithium Chloride; Myocardium; Norepinephrine; Phosphorylation; Propranolol; Rats; Stimulation, Chemical; Tritium | 1992 |
Intrinsic fluctuations of phosphoinositol levels are involved in the progression of the naturally synchronous cell cycle in Physarum polycephalum.
Topics: Animals; Cell Cycle; Chlorides; Inositol; Inositol 1,4,5-Trisphosphate; Lithium; Lithium Chloride; Phosphatidylinositols; Physarum polycephalum; Tritium | 1992 |
The thiol reagent, thimerosal, evokes Ca2+ spikes in HeLa cells by sensitizing the inositol 1,4,5-trisphosphate receptor.
Topics: Calcium; Calcium Channels; Fura-2; Glutathione; HeLa Cells; Histamine; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Kinetics; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Spectrometry, Fluorescence; Thimerosal; Time Factors | 1992 |
The phosphoinositide pathway of lymphoid cells: labeling after permeabilization by alveolysin, a bacterial sulfhydryl-activated cytolysin.
Topics: Burkitt Lymphoma; Hemolysin Proteins; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Organic Chemicals; Signal Transduction; Tumor Cells, Cultured | 1992 |
Lithium enhances accumulation of [3H]inositol radioactivity and mass of second messenger inositol 1,4,5-trisphosphate in monkey cerebral cortex slices.
Topics: Acetylcholine; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Female; Inositol; Inositol 1,4,5-Trisphosphate; Lithium; Macaca mulatta; Second Messenger Systems; Tritium | 1992 |
Inhibition of agonist-induced activation of phospholipase C following poxvirus infection.
Topics: Adenosine Triphosphate; Amanitins; Animals; Calcium; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Viral; Chlorocebus aethiops; Cycloheximide; Enzyme Activation; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kidney; Kinetics; RNA, Messenger; Tumor Cells, Cultured; Type C Phospholipases; Vaccinia virus | 1992 |
Inositol 1,4,5-trisphosphate metabolism in the cerebella of Lurcher mutant mice and patients with olivopontocerebellar atrophy.
Topics: Animals; Cell Membrane; Cerebellum; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; Mice, Neurologic Mutants; Microsomes; Middle Aged; Olivopontocerebellar Atrophies | 1992 |
Different pathways of inositol phosphate metabolism in intact neonatal rat hearts and isolated cardiomyocytes.
Topics: Animals; Animals, Newborn; Heart; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Myocardium; Norepinephrine; Phosphatidylinositols; Phosphorylation | 1992 |
Calcium homeostasis in procyclic and bloodstream forms of Trypanosoma brucei. Lack of inositol 1,4,5-trisphosphate-sensitive Ca2+ release.
Topics: Adenine Nucleotides; Animals; Calcium; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Cytosol; Digitonin; Fura-2; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Spectrometry, Fluorescence; Trypanosoma brucei brucei; Vanadates | 1992 |
Intercellular communication between follicular angiotensin receptors and Xenopus laevis oocytes: medication by an inositol 1,4,5-trisphosphate-dependent mechanism.
Topics: Angiotensin II; Animals; Calcium; Cell Communication; Dose-Response Relationship, Drug; Female; Heparin; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intercellular Junctions; Ionomycin; Kinetics; Oocytes; Receptors, Angiotensin; Signal Transduction; Xenopus laevis | 1992 |
Effects of inositol hexaphosphate on growth and differentiation in K-562 erythroleukemia cell line.
Topics: Cell Differentiation; Cell Division; Humans; Inosine Diphosphate; Inositol; Inositol 1,4,5-Trisphosphate; Leukemia, Erythroblastic, Acute; Phytic Acid; Time Factors; Tritium; Tumor Cells, Cultured | 1992 |
Alpha 1-adrenergic and muscarinic-cholinergic stimulated inositol trisphosphate production may proceed through different post-receptor signal transduction pathways in parotid acini.
Topics: Animals; Carbachol; Epinephrine; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Parotid Gland; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Signal Transduction | 1991 |
Role of inositol triphosphate isomer formation in type II pneumocyte signal transduction.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Calcium; Cells, Cultured; Chlorides; Chromatography, High Pressure Liquid; Egtazic Acid; Fluorescent Dyes; Indoles; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Lithium; Lithium Chloride; Lung; Male; Rats; Signal Transduction | 1991 |
Differences in the coupling of ET-1 and LPA receptors in Ins(1,4,5)P3 formation in Rat-1 fibroblasts.
Topics: Animals; Cell Line; Endothelins; Fibroblasts; Guanosine 5'-O-(3-Thiotriphosphate); Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lysophospholipids; Rats; Receptors, Cell Surface; Receptors, Endothelin | 1991 |
Characterization of glucocorticoid inhibition of antigen-induced inositolphosphate formation by rat basophilic leukemia cells: possible involvement of phosphatases.
Topics: Animals; Antigens; Cycloheximide; Dexamethasone; Dinitrophenols; Glucocorticoids; Hydrocortisone; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Leukemia, Basophilic, Acute; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Phosphoric Monoester Hydrolases; Rats; Serum Albumin, Bovine; Tumor Cells, Cultured | 1991 |
Effect of protein kinase A on inositide metabolism and rap 1 G-protein in human erythroleukemia cells.
Topics: Cell Line; Cell Membrane; Cytosol; Epoprostenol; Humans; Iloprost; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Leukemia, Erythroblastic, Acute; Membrane Proteins; Phosphorylation; Protein Kinases; Thrombin; Tumor Cells, Cultured | 1990 |
Ca2+ release and InsP3 production in avian uterine cells: effects of PGF2 alpha and AVT.
Topics: Animals; Calcium; Chickens; Dinoprost; Female; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Muscle, Smooth; Ruthenium Red; Uterus; Vanadates; Vasotocin; Verapamil | 1990 |
TGF-beta inhibits the platelet-derived growth factor-induced formation of inositol trisphosphate in MG-63 human osteosarcoma cells.
Topics: Cell Division; Cell Line; Fibroblast Growth Factor 1; Humans; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Osteosarcoma; Phosphatidylinositols; Platelet-Derived Growth Factor; Transforming Growth Factor beta | 1990 |
Relationship between the calcium-mobilizing action of inositol 1,4,5-trisphosphate in permeable AR4-2J cells and the estimated levels of inositol 1,4,5-trisphosphate in intact AR4-2J cells.
Topics: Animals; Binding Sites; Biological Transport, Active; Calcium; Cell Line; Cell Membrane; Cell Membrane Permeability; Electric Stimulation; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Substance P; Tritium | 1991 |
Inositol 1,4,5-trisphosphate compartmentalization in tracheal smooth muscle.
Topics: Animals; Atropine; Carbachol; Chromatography, High Pressure Liquid; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Models, Biological; Muscle Contraction; Muscle, Smooth; Swine; Trachea; Tritium | 1992 |
Decreased formation of inositol trisphosphate in Madin-Darby canine kidney cells under conditions of beta-glucosidase inhibition.
Topics: Animals; beta-Glucosidase; Bradykinin; Cell Line; Dogs; Galactose; Glucosylceramides; Guanosine 5'-O-(3-Thiotriphosphate); Inositol; Inositol 1,4,5-Trisphosphate; Kidney; Kinetics; Palmitic Acid; Palmitic Acids; Radioisotope Dilution Technique; Sphingolipids; Tritium | 1992 |
Inositol and inositol 1,4,5-trisphosphate content of Down syndrome fibroblasts exhibiting enhanced inositol uptake.
Topics: Biological Transport; Cells, Cultured; Down Syndrome; Fibroblasts; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Reference Values; Skin | 1991 |
Diethylstilbestrol stimulates persistent phosphatidylinositol lipid turnover by an estrogen receptor-mediated mechanism in immature mouse uterus.
Topics: Animals; Dienestrol; Diethylstilbestrol; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Female; Inositol; Inositol 1,4,5-Trisphosphate; Lipid Metabolism; Mice; Mice, Inbred Strains; Phosphatidylinositols; Polyunsaturated Alkamides; Receptors, Estrogen; Uterus | 1991 |
Accumulation and metabolism of Ins(1,4,5)P3 and Ins(1,3,4,5)P4 in muscarinic-receptor-stimulated SH-SY5Y neuroblastoma cells.
Topics: Animals; Carbachol; Cell Line; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Mice; Neuroblastoma; Receptors, Muscarinic | 1991 |
Possible involvement of inositol-lipid metabolism in malignant hyperthermia.
Topics: Animals; Electric Stimulation; Heart; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoproterenol; Lipid Metabolism; Malignant Hyperthermia; Myocardium; Phenylephrine; Swine | 1991 |
Intramural pericyte degeneration in early diabetic retinopathy study in vitro.
Topics: Animals; Arterioles; Capillaries; Cattle; Cells, Cultured; Diabetic Retinopathy; DNA; Glucose; Inositol; Inositol 1,4,5-Trisphosphate; Phosphatidylinositols; Retinal Artery | 1990 |
Inositol trisphosphate levels in cells expressing wild-type and mutant polyomavirus middle T antigens: evidence for activation of phospholipase C via activation of pp60c-src.
Topics: Animals; Antigens, Polyomavirus Transforming; Cell Line; Cell Transformation, Viral; Cells, Cultured; Enzyme Activation; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Mutation; Oncogene Protein pp60(v-src); Polyomavirus; Rats; Type C Phospholipases | 1990 |
Heparin inhibits Na(+)-H+ exchange in vascular smooth muscle cells.
Topics: Amiloride; Angiotensin II; Animals; Aorta, Thoracic; Carrier Proteins; Cattle; Cells, Cultured; Endothelium, Vascular; Epidermal Growth Factor; Glycosaminoglycans; Heparin; Hydrogen-Ion Concentration; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Male; Mice; Mice, Inbred Strains; Muscle, Smooth, Vascular; Ouabain; Platelet-Derived Growth Factor; Rats; Rats, Inbred WF; Sodium; Sodium-Hydrogen Exchangers | 1990 |
Formation of inositol pentakisphosphate by ovarian follicles of Xenopus laevis from metabolism of inositol (1,4,5)trisphosphate and inositol (1,3,4,5)tetrakisphosphate and from receptor activation.
Topics: Acetylcholine; Animals; Chromatography, High Pressure Liquid; Female; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Ovarian Follicle; Receptors, Cell Surface; Thionucleotides; Xenopus laevis | 1990 |
Lipoxin A4 inhibits phosphoinositide hydrolysis in human neutrophils.
Topics: Dose-Response Relationship, Drug; Humans; Hydrolysis; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Leukotriene B4; Lipoxins; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositols | 1990 |
Effect of thrombin on calcium homeostasis in chick embryonic heart cells. Receptor-operated calcium entry with inositol trisphosphate and a pertussis toxin-sensitive G protein as second messengers.
Topics: Animals; Calcium; Calcium Channels; Chick Embryo; Fluorescent Dyes; GTP-Binding Proteins; Heart Ventricles; Homeostasis; Indoles; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Myocardium; Pertussis Toxin; Second Messenger Systems; Thrombin; Ventricular Function; Verapamil; Virulence Factors, Bordetella | 1990 |
Myo-inositol does not modulate PI turnover in MDCK cells under hyperosmolar conditions.
Topics: Animals; Binding, Competitive; Bradykinin; CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase; Cell Line; Inositol; Inositol 1,4,5-Trisphosphate; Kidney; Osmolar Concentration; Phosphatidylinositols; Phosphotransferases; Time Factors; Transferases (Other Substituted Phosphate Groups) | 1990 |
Species differences in the effects of leukotriene D4 on inositol trisphosphate accumulation, cyclic AMP formation and contraction in iris sphincter of the mammalian eye.
Topics: Animals; Cats; Cattle; Cyclic AMP; Dinoprost; Humans; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Iris; Muscle Contraction; Rabbits; Radioimmunoassay; Species Specificity; SRS-A; Swine | 1990 |
Ca2+ release by inositol-trisphosphorothioate in isolated triads of rabbit skeletal muscle.
Topics: Animals; Calcium; Calcium Channels; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Lipid Bilayers; Models, Biological; Muscles; Organothiophosphorus Compounds; Phosphatidylethanolamines; Phosphatidylserines; Rabbits; Second Messenger Systems | 1990 |
Phosphoinositide metabolism in intestinal brush borders: stimulation of IP3 formation by guanine nucleotides and Ca2+.
Topics: Adenosine Triphosphate; Animals; Calcium; Egtazic Acid; Epithelium; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Jejunum; Kinetics; Male; Membrane Lipids; Microvilli; Muscle, Smooth; Phosphatidylinositols; Rats; Rats, Inbred Strains; Thionucleotides | 1990 |
Calcium entry in rat hepatocytes: stimulation by inositol 1,4,5-trisphosphorothioate.
Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Guanosine 5'-O-(3-Thiotriphosphate); Inositol; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Liver; Organothiophosphorus Compounds; Phenylephrine; Rats; Second Messenger Systems | 1990 |
Muscarinic receptor-mediated inositol tetrakisphosphate response in bovine adrenal chromaffin cells.
Topics: 2,3-Diphosphoglycerate; Adrenal Medulla; Animals; Atropine; Cattle; Cells, Cultured; Chlorides; Diphosphoglyceric Acids; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Muscarine; Receptors, Muscarinic; Second Messenger Systems | 1990 |
The effects of acute and chronic lithium treatment on pilocarpine-stimulated phosphoinositide hydrolysis in mouse brain in vivo.
Topics: Animals; Atropine; Brain; Diet; Hydrolysis; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Lithium; Male; Mice; Mice, Inbred C57BL; Phosphatidylinositols; Pilocarpine | 1990 |
Anti-insulin antiserum increases inositol phosphate accumulation in rat pancreatic islets.
Topics: Animals; Female; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Insulin Antibodies; Islets of Langerhans; Kinetics; Male; Rats; Rats, Inbred Strains | 1990 |
Inhibition of inositol 1,4,5-trisphosphate metabolism in permeabilised SH-SY5Y human neuroblastoma cells by a phosphorothioate-containing analogue of inositol 1,4,5-trisphosphate.
Topics: Animals; Carbachol; Cell Line; Cell Membrane; Cell Membrane Permeability; Electric Stimulation; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Neuroblastoma; Organothiophosphorus Compounds | 1990 |
Oxytocin-stimulated inositol phosphate turnover in endometrium of ewes is influenced by stage of the estrous cycle, pregnancy, and intrauterine infusion of ovine conceptus secretory proteins.
Topics: Animals; Endometrium; Estrus; Female; Inositol; Inositol 1,4,5-Trisphosphate; Interferon Type I; Oxytocin; Pregnancy; Pregnancy Proteins; Pregnancy, Animal; Progesterone; Sheep | 1990 |
Receptor-activated calcium entry in exocrine cells does not occur via agonist-sensitive intracellular pools.
Topics: Animals; Calcium; Carbachol; Ducks; Inositol; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Models, Biological; Nasal Cavity; Organothiophosphorus Compounds; Receptors, Muscarinic; Salt Gland | 1990 |
Origins of myo-inositol tetrakisphosphates in agonist-stimulated rat pancreatoma cells. Stimulation by bombesin of myo-inositol 1,3,4,5,6-pentakisphosphate breakdown to myo-inositol 3,4,5,6-tetrakisphosphate.
Topics: Animals; Bombesin; Chromatography, High Pressure Liquid; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Pancreatic Neoplasms; Rats; Tumor Cells, Cultured | 1990 |
Agonist-stimulated inositol phosphate metabolism in avian erythrocytes.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Chickens; Erythrocytes; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Phosphates; Phosphorylation; Thionucleotides | 1990 |
Lacrimal gland inositol trisphosphate isomer and inositol tetrakisphosphate production.
Topics: Animals; Calcium; Carbachol; Chromatography, High Pressure Liquid; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isomerism; Kinetics; Lacrimal Apparatus; Male; Rats; Rats, Inbred Strains; Signal Transduction | 1990 |
Effects of inositol, 1,4,5-trisphosphate injections into cat spinal motoneurons.
Topics: Anesthesia; Animals; Calcium; Cats; Chelating Agents; Decerebrate State; Electric Stimulation; Injections; Inositol; Inositol 1,4,5-Trisphosphate; Iontophoresis; Lithium; Motor Neurons; Potassium Channels; Spinal Cord | 1990 |
Inositol trisphosphate production and amylase secretion in mouse pancreatic acini.
Topics: Amylases; Animals; Carbachol; Ceruletide; Dose-Response Relationship, Drug; Female; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Mice; Pancreas; Sugar Phosphates | 1985 |
Turnover of inositol phospholipids in cultured murine keratinocytes: possible involvement of inositol triphosphate in cellular differentiation.
Topics: Animals; Calcium; Cell Differentiation; Cell Division; Cells, Cultured; Epidermal Cells; Epidermis; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Keratins; Mice; Mice, Inbred BALB C; Phosphatidylinositols | 1988 |
The calcium signal for Balb/MK keratinocyte terminal differentiation induces sustained alterations in phosphoinositide metabolism without detectable protein kinase C activation.
Topics: Animals; Calcium; Cell Differentiation; Cell Line; Cyclooxygenase Inhibitors; Diglycerides; Enzyme Activation; Epidermal Cells; Epidermal Growth Factor; ErbB Receptors; Extracellular Matrix; Glycerol; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Keratins; Lipoxygenase Inhibitors; Mice; Phosphatidylinositols; Phosphorylation; Protease Inhibitors; Protein Kinase C; Type C Phospholipases | 1989 |
Extracellular ATP stimulates poly(inositol phospholipid) hydrolysis and eicosanoid synthesis in mouse peritoneal macrophages in culture.
Topics: Adenosine Triphosphate; Animals; Calcimycin; Cells, Cultured; Dinoprostone; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Macrophages; Mice; Mice, Inbred Strains; Peritoneal Cavity; SRS-A; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1989 |
A metabolically stable analog of 1,4,5-inositol trisphosphate activates a novel K+ conductance in pyramidal cells of the rat hippocampal slice.
Topics: Action Potentials; Animals; Barium; Calcium; Egtazic Acid; Electric Conductivity; Electrophysiology; Hippocampus; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Male; Organothiophosphorus Compounds; Potassium; Rats; Reaction Time | 1989 |
myo-inositol 1,4,5-trisphosphorothioate is a potent competitive inhibitor of human erythrocyte 5-phosphatase.
Topics: Erythrocytes; Humans; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Polyphosphate 5-Phosphatases; Kinetics; Organothiophosphorus Compounds; Phosphoric Monoester Hydrolases | 1989 |
Dissociation of inositol trisphosphate from diacylglycerol production in Rous sarcoma virus-transformed fibroblasts.
Topics: Animals; Avian Sarcoma Viruses; Blood; Cell Line, Transformed; Cell Transformation, Viral; Chick Embryo; Diglycerides; Fibroblasts; Glycerides; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Oncogene Protein pp60(v-src); Phosphatidic Acids; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Retroviridae Proteins; Sugar Phosphates | 1989 |
Chemoattractant and guanosine 5'-[gamma-thio]triphosphate induce the accumulation of inositol 1,4,5-trisphosphate in Dictyostelium cells that are labelled with [3H]inositol by electroporation.
Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cyclic AMP; Dictyostelium; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Phospholipids; Rats; Stimulation, Chemical; Sugar Phosphates; Thionucleotides | 1989 |
Twenty-fifth Colworth medal lecture. The cellular functions of myo-inositol.
Topics: Adenylyl Cyclases; Animals; Cells, Cultured; Erythrocytes; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Phosphatidylinositols; Phosphoric Diester Hydrolases; Substrate Specificity; Turkeys | 1989 |
Ca2+ fluxes and phosphoinositides in hepatocytes.
Topics: Animals; Calcium; Calcium Radioisotopes; Cells, Cultured; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cytosol; Hormones; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Liver; Phosphatidylinositols; Radioisotope Dilution Technique; Rats; Tritium | 1989 |
Muscarinic-agonist and guanine nucleotide stimulation of myo-inositol trisphosphate formation in membranes isolated from bovine iris sphincter smooth muscle: effects of short-term cholinergic desensitization.
Topics: Animals; Calcium; Cattle; Cell Membrane; Guanine Nucleotides; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Iris; Membranes; Muscle, Smooth; Parasympathetic Nervous System; Parasympathomimetics; Pertussis Toxin; Phosphatidylinositols; Stimulation, Chemical; Type C Phospholipases; Virulence Factors, Bordetella | 1989 |
Depolarization potentiates endothelin-induced effects on cytosolic calcium in bovine adrenal chromaffin cells.
Topics: Adrenal Medulla; Angiotensin II; Animals; Benzofurans; Calcium; Cattle; Cells, Cultured; Cytosol; Endothelins; Endothelium, Vascular; Fura-2; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Membrane Potentials; Nicotine; Norepinephrine; Peptides; Phosphatidylinositols; Potassium Chloride | 1989 |
An analysis of myo-[3H]inositol trisphosphates found in myo-[3H]inositol prelabelled avian erythrocytes.
Topics: Animals; Chickens; Erythrocytes; Inositol; Inositol 1,4,5-Trisphosphate; L-Iditol 2-Dehydrogenase; Male; Rats; Stereoisomerism; Sugar Alcohols; Tritium | 1989 |
Activation of calcium entry by the tumor promoter thapsigargin in parotid acinar cells. Evidence that an intracellular calcium pool and not an inositol phosphate regulates calcium fluxes at the plasma membrane.
Topics: Animals; Biological Transport; Calcium; Carcinogens; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Ethers; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Kinetics; Methacholine Chloride; Methacholine Compounds; Models, Biological; Parotid Gland; Plant Extracts; Rats; Signal Transduction; Sugar Phosphates; Thapsigargin | 1989 |
Effect of cholecystokinin on the accumulation of inositol phosphates in isolated pancreatic islets.
Topics: Animals; Glucose; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Radioisotope Dilution Technique; Rats; Sincalide; Tritium | 1989 |
Synthetic diacylglycerols trigger an increase of intracellular free calcium in promyelocytic HL60 cells.
Topics: Benzofurans; Calcium; Cell Line; Cell Membrane Permeability; Diglycerides; Fura-2; Glycerides; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Leukemia, Promyelocytic, Acute; Potassium; Sodium; Spectrometry, Fluorescence; Tetradecanoylphorbol Acetate | 1989 |
Formation of [3H]inositol metabolites in rat hippocampal formation slices prelabelled with [3H]inositol and stimulated with carbachol.
Topics: Animals; Carbachol; Chromatography, High Pressure Liquid; Hippocampus; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Rats; Tritium | 1989 |
Inositol 1,4,5-trisphosphorothioate, a stable analogue of inositol trisphosphate which mobilizes intracellular calcium.
Topics: Animals; Calcium; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Organothiophosphorus Compounds; Phosphorylation; Rats | 1989 |
Calcium oscillations.
Topics: Action Potentials; Animals; Calcium; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; Organothiophosphorus Compounds | 1989 |
Analysis of inositol tris- and tetrakisphosphate in mesangial cells by HPLC.
Topics: Angiotensin II; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Glomerular Mesangium; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Rats; Sugar Phosphates; Tritium | 1989 |
Alpha 1-adrenergic inositol trisphosphate production in brown adipocytes is Na+ dependent.
Topics: Adipose Tissue, Brown; Animals; Cells, Cultured; Cricetinae; Egtazic Acid; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lithium; Mesocricetus; Norepinephrine; Oxygen Consumption; Receptors, Adrenergic, alpha; Sodium; Sugar Phosphates | 1987 |
Stimulation of phosphatidylinositol metabolism in the isolated, perfused rat heart.
Topics: Animals; Atropine; Bucladesine; Calcium; Carbachol; Chlorides; Heart Atria; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Lithium Chloride; Male; Mast Cells; Myocardium; Norepinephrine; Perfusion; Phosphatidylinositols; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1987 |
Reduction of inositol triphosphate in retinal microvessels by glucose and restimulation by myo-inositol.
Topics: Animals; Capillaries; Glucose; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Oxidation-Reduction; Phosphatidylinositol Phosphates; Phosphatidylinositols; Retinal Vessels; Sugar Phosphates; Swine | 1987 |
Follicle-stimulating hormone modulation of phosphoinositide turnover in the immature rat Sertoli cell in culture.
Topics: Animals; Cells, Cultured; Chorionic Gonadotropin; Follicle Stimulating Hormone; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Luteinizing Hormone; Male; Phosphatidylinositols; Rats; Rats, Inbred Strains; Reference Values; Sertoli Cells; Thyrotropin | 1988 |
Norepinephrine stimulates the production of inositol trisphosphate and inositol tetrakisphosphate in rat aorta.
Topics: Animals; Aorta, Thoracic; Chlorides; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Male; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Inbred Strains; Reference Values; Sugar Phosphates | 1988 |
Myo-inositol(1,4,5)trisphosphorothioate binds to specific [3H]inositol(1,4,5)trisphosphate sites in rat cerebellum and is resistant to 5-phosphatase.
Topics: Animals; Binding Sites; Cerebellum; Erythrocyte Membrane; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Organothiophosphorus Compounds; Phosphoric Monoester Hydrolases; Rats; Stereoisomerism | 1988 |
Right atrial dilatation increases inositol-(1,4,5)trisphosphate accumulation. Implications for the control of atrial natriuretic peptide release.
Topics: Animals; Atrial Function; Atrial Natriuretic Factor; Chromatography, High Pressure Liquid; Dilatation; Heart; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Myocardium; Phosphatidylinositols; Rats; Sugar Phosphates | 1988 |
Ca2+-mediated generation of inositol 1,4,5-triphosphate and inositol 1,3,4,5-tetrakisphosphate in pancreatic islets. Studies with K+, glucose, and carbamylcholine.
Topics: Animals; Calcium; Carbachol; Glucose; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Islets of Langerhans; Kinetics; Male; Potassium; Rats; Rats, Inbred Strains; Sugar Phosphates; Tritium | 1987 |
Agonist-induced desensitization of muscarinic receptor-mediated calcium efflux without concomitant desensitization of phosphoinositide hydrolysis.
Topics: Astrocytoma; Calcium; Carbachol; Cell Line; Chromatography, Ion Exchange; Humans; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; N-Methylscopolamine; Phosphatidylinositols; Receptors, Muscarinic; Scopolamine Derivatives; Time Factors | 1985 |
Surgical sympathetic denervation increases alpha 1-adrenoceptor-mediated accumulation of myo-inositol trisphosphate and muscle contraction in rabbit iris dilator smooth muscle.
Topics: Adenosine Triphosphatases; Animals; Arachidonic Acid; Arachidonic Acids; Female; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Iris; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Phosphatidylinositols; Phospholipids; Protein Kinase C; Rabbits; Rats; Receptors, Adrenergic, alpha; Sugar Phosphates; Sympathectomy | 1986 |
Gonadotropin-releasing hormone (GnRH) rapidly stimulates the formation of inositol phosphates and diacyglycerol in rat granulosa cells: further evidence for the involvement of Ca2+ and protein kinase C in the action of GnRH.
Topics: Animals; Calcium; Chlorides; Diglycerides; Female; Glycerides; Gonadotropin-Releasing Hormone; Granulosa Cells; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lithium; Lithium Chloride; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Inbred Strains; Sugar Phosphates | 1986 |
Inositol lipid metabolism and signal transduction in clonal pituitary cells.
Topics: Animals; Calcium; Cell Line; Diglycerides; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Phosphatidylinositol Phosphates; Phosphatidylinositols; Pituitary Gland; Pituitary Neoplasms; Prolactin; Protein Kinase C; Rats; Receptors, Cell Surface; Thyrotropin-Releasing Hormone | 1986 |
Interleukin 2 rapidly stimulates synthesis and breakdown of polyphosphoinositides in interleukin 2-dependent, murine T-cell lines.
Topics: Animals; Cell Line; Diglycerides; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Interleukin-2; Kinetics; Mice; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; T-Lymphocytes, Cytotoxic | 1987 |
Heat stress stimulates inositol trisphosphate release and phosphorylation of phosphoinositides in CHO and Balb C 3T3 cells.
Topics: Animals; Cell Line; Cell Membrane; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Female; Hot Temperature; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Membrane Lipids; Mice; Mice, Inbred BALB C; Ovary; Phosphatidylinositols; Phosphorylation; Sugar Phosphates | 1987 |
Thyrotropin-releasing hormone-stimulated inositol trisphosphate formation is liable to thyrotropin-releasing hormone-induced desensitization by a calcium-dependent mechanism.
Topics: Animals; Calcium; Cells, Cultured; Enzyme Activation; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Protein Kinase C; Sugar Phosphates; Thyrotropin-Releasing Hormone | 1988 |
Inositol lipid cascade of vision studied in mutant flies.
Topics: Animals; Drosophila; GTP-Binding Proteins; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Rhodopsin; Second Messenger Systems; Signal Transduction; Sugar Phosphates; Type C Phospholipases; Vision, Ocular | 1988 |
Metabolism of inositol bis-, tris-, tetrakis- and pentakis-phosphates in GH3 cells.
Topics: Animals; Cell Line; Chromatography, High Pressure Liquid; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Pituitary Neoplasms; Rats; Sugar Phosphates; Tumor Cells, Cultured | 1988 |
Thrombin-induced inositol trisphosphate production by rabbit platelets is inhibited by ethanol.
Topics: Adenosine Diphosphate; Animals; Blood Platelets; Cytoplasmic Granules; Ethanol; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Light; Platelet Aggregation; Rabbits; Sugar Phosphates; Thrombin | 1988 |
Inositol uptake and metabolism in molluscan neuronal tissue.
Topics: Animals; Biological Transport; Carbachol; Cell Membrane; Electric Stimulation; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lymnaea; Membrane Lipids; Neurons; Sodium; Type C Phospholipases | 1988 |
Stereospecific mobilization of intracellular Ca2+ by inositol 1,4,5-triphosphate. Comparison with inositol 1,4,5-trisphosphorothioate and inositol 1,3,4-trisphosphate.
Topics: Calcium; Cell Line; Dose-Response Relationship, Drug; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Fluid; Organothiophosphorus Compounds; Stereoisomerism; Sugar Phosphates; Tumor Cells, Cultured | 1988 |
Malignant transformation by ras and other oncogenes produces common alterations in inositol phospholipid signaling pathways.
Topics: Animals; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cells, Cultured; Genes, ras; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; Oncogenes; Rats; Sugar Phosphates; Tritium | 1988 |
DL-myo-inositol 1,4,5-trisphosphorothioate mobilizes intracellular calcium in Swiss 3T3 cells and Xenopus oocytes.
Topics: Animals; Calcium; Cell Membrane Permeability; Cells, Cultured; Female; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Mice; Oocytes; Organothiophosphorus Compounds; Xenopus laevis | 1988 |
Quantitative changes in inositol 1,4,5-trisphosphate in chemoattractant-stimulated neutrophils.
Topics: Animals; Calcium Radioisotopes; Chromatography, High Pressure Liquid; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Sugar Phosphates; Tritium | 1986 |
Metabolism of inositol 1,4,5-trisphosphate in guinea-pig hepatocytes.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Angiotensin II; Animals; Cell Separation; Chromatography, High Pressure Liquid; Diphosphoglyceric Acids; Guinea Pigs; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver; Male; Sugar Phosphates | 1987 |
Luteinizing hormone increases inositol trisphosphate and cytosolic free Ca2+ in isolated bovine luteal cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cattle; Colforsin; Corpus Luteum; Cytosol; Female; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Luteinizing Hormone; Phosphates; Sugar Phosphates | 1987 |
Regulation of inositol phosphate metabolism in chemoattractant-stimulated human polymorphonuclear leukocytes. Definition of distinct dephosphorylation pathways for IP3 isomers.
Topics: Adenosine Triphosphate; Benzofurans; Chemotaxis, Leukocyte; Chromatography, High Pressure Liquid; Ethers; Fura-2; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Isomerism; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Sugar Phosphates | 1987 |
Transduction of mitogenic signals in T lymphocytes. Role of inositol phospholipids for the rapid activation of ornithine decarboxylase.
Topics: Enzyme Activation; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Lymphocyte Activation; Ornithine Decarboxylase; Phosphatidylinositols; Putrescine; T-Lymphocytes | 1987 |
Glucose-induced accumulation of inositol trisphosphates in isolated pancreatic islets. Predominance of the 1,3,4-isomer.
Topics: Animals; Chromatography, High Pressure Liquid; Glucose; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Islets of Langerhans; Isomerism; Male; Rats; Rats, Inbred Strains; Sugar Phosphates | 1986 |
Novel aspects of gonadotropin-releasing hormone action on inositol polyphosphate metabolism in cultured pituitary gonadotrophs.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Female; Gonadotropin-Releasing Hormone; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lithium; Phosphates; Pituitary Gland, Anterior; Rats; Sugar Phosphates; Type C Phospholipases | 1987 |
Inositol trisphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor.
Topics: Animals; Calcium; Cells, Cultured; DNA; Fibroblasts; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; Mice, Inbred Strains; Phosphatidylinositols; Platelet-Derived Growth Factor; Sugar Phosphates | 1984 |
Rapid accumulation of inositol trisphosphate reveals that agonists hydrolyse polyphosphoinositides instead of phosphatidylinositol.
Topics: Animals; Diptera; Female; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Models, Biological; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipids; Salivary Glands; Serotonin; Sugar Phosphates | 1983 |
Inositol trisphosphates in carbachol-stimulated rat parotid glands.
Topics: Animals; Carbachol; Chromatography, Ion Exchange; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Parotid Gland; Phosphates; Rats; Stimulation, Chemical; Sugar Alcohols; Sugar Phosphates | 1984 |
Antinociceptive defect of beige-J mice reversed by i.c.v. IP3 or myo-inositol.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Injections, Intraventricular; Inositol; Inositol 1,4,5-Trisphosphate; Male; Mice; Mice, Inbred C57BL; Morphine; Pain; Pain Measurement; Reaction Time; Second Messenger Systems | 1995 |
Membrane potential regulates Ca2+ uptake and inositol phosphate generation in rat sublingual mucous acini.
Topics: Animals; Biological Transport; Calcium; Carbachol; Feedback; Inositol; Inositol 1,4,5-Trisphosphate; Intracellular Fluid; Ion Channel Gating; Ion Channels; Male; Manganese; Membrane Potentials; Nifedipine; Rats; Receptors, Muscarinic; Sublingual Gland; Terpenes; Thapsigargin | 1993 |
Desalting inositolpolyphosphates by dialysis.
Topics: Adenosine Triphosphate; Animals; Dialysis; Dictyostelium; Glucose-6-Phosphate; Glucosephosphates; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Osmolar Concentration; Phosphorus Radioisotopes; Phytic Acid; Radioisotope Dilution Technique; Salts; Tritium | 1995 |
Nitrergic stimulation does not inhibit carbachol-induced inositol phosphate generation in the rat anococcygeus.
Topics: Anal Canal; Animals; Atropine; Carbachol; Cyclic GMP; Electric Stimulation; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Male; Muscle, Smooth; Nitroprusside; Rats; Rats, Wistar | 1994 |
Functional platelet-activating factor receptors linked to inositol lipid hydrolysis, calcium mobilization and tyrosine kinase activity in the human endometrial HEC-1B cell line.
Topics: Azepines; Calcium; Cell Line; Endometrium; Female; Fura-2; Humans; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Lipid Metabolism; Platelet Activating Factor; Platelet Membrane Glycoproteins; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Triazoles | 1994 |
The preparation of intermediates for the synthesis of 1D-myo-inositol 1,4,5- and 2,4,5-trisphosphates, 1,4-bisphosphate 5-phosphorothioate, and 4,5-bisphosphate 1-phosphorothioate from 1D-3,6-di-O-benzyl-1,2-O-isopropylidene-myo-inositol.
Topics: Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Molecular Structure; Organothiophosphorus Compounds | 1994 |
The metabolism of D-myo-inositol 1,4,5-trisphosphate and D-myo-inositol 1,3,4,5-tetrakisphosphate by porcine skeletal muscle.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Fractionation; Chromatography, High Pressure Liquid; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Magnesium; Muscles; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Solubility; Subcellular Fractions; Swine | 1994 |
Effects of L-690,488, a prodrug of the bisphosphonate inositol monophosphatase inhibitor L-690,330, on phosphatidylinositol cycle markers.
Topics: Animals; Carbachol; Cell Membrane Permeability; Cerebral Cortex; CHO Cells; Cricetinae; Cytidine; Cytidine Monophosphate; Diphosphonates; Glycerophospholipids; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Male; Phosphatidic Acids; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Prodrugs; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Tritium | 1994 |
Octopamine enhances phagocytosis in cockroach hemocytes: involvement of inositol trisphosphate.
Topics: Analysis of Variance; Animals; Hemocytes; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Octopamine; Periplaneta; Phagocytosis; Serotonin; Staphylococcus aureus | 1994 |
Mouse oocyte maturation is affected by lithium via the polyphosphoinositide metabolism and the microtubule network.
Topics: Actin Cytoskeleton; Animals; Chromosomes; Female; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Lithium; Mice; Microtubules; Oocytes; Oogenesis; Phosphatidylinositol Phosphates | 1994 |
Sphingosine-1-phosphate, a putative second messenger, mobilizes calcium from internal stores via an inositol trisphosphate-independent pathway.
Topics: 3T3 Cells; Animals; Arachidonic Acid; Bradykinin; Calcium; Calcium-Transporting ATPases; Cytosol; DNA; Egtazic Acid; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Kinetics; Lysophospholipids; Mice; Phorbol Esters; Second Messenger Systems; Sphingosine; Terpenes; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors | 1994 |
Second messenger interactions in the rat adrenal cortex.
Topics: Adrenocorticotropic Hormone; Aldosterone; alpha-MSH; Angiotensin II; Animals; Bucladesine; Cells, Cultured; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Rats; Second Messenger Systems; Zona Glomerulosa | 1993 |
A chemoenzymatic synthesis of D-myo-inositol 1,4,5-trisphosphate.
Topics: Indicators and Reagents; Inositol; Inositol 1,4,5-Trisphosphate; Lipase; Magnetic Resonance Spectroscopy; Molecular Structure; Optical Rotation; Pseudomonas; Spectrophotometry, Infrared; Stereoisomerism | 1994 |
Multivariate and vectorial analysis of pharmacological signalling: diaphragm inositol 1,4,5-triphosphate under the duress of burn trauma.
Topics: Animals; Burns; Diaphragm; Glycerophosphates; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mice; Multivariate Analysis; Signal Transduction; Specific Pathogen-Free Organisms | 1994 |
Characterization of the effects of lithium on phosphatidylinositol (PI) cycle activity in human muscarinic m1 receptor-transfected CHO cells.
Topics: Animals; Carbachol; CHO Cells; Cricetinae; Cytidine Monophosphate; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Lithium; Phosphatidylinositols; Radioligand Assay; Receptors, Muscarinic; Second Messenger Systems; Transfection | 1993 |
Interaction between signal transduction pathways contributing to gallbladder tonic contraction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium; Calmodulin; Cats; Diglycerides; Female; Gallbladder; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Isoquinolines; Male; Models, Biological; Muscle Contraction; Muscle Tonus; Muscle, Smooth; Myosin-Light-Chain Kinase; Myosins; Phosphorylation; Piperazines; Protein Kinase C; Signal Transduction; Strontium; Sulfonamides; Tetrodotoxin | 1993 |
Multivariate influence of polyinositols on IP3 in diaphragm: individually applied matrix and vectorial analysis of trauma from small and large body surface area burn groups.
Topics: Analysis of Variance; Animals; Body Surface Area; Burns; Diaphragm; Disease Models, Animal; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Male; Mice; Multivariate Analysis; Ointments; Polymers; Regression Analysis; Signal Transduction; Silver Sulfadiazine | 1993 |
Evidence against a direct role for inositol phosphate metabolism in the circadian oscillator and the blue-light signal transduction pathway in Neurospora crassa.
Topics: Circadian Rhythm; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Light; Lithium; Neurospora crassa; Signal Transduction | 1993 |
Interleukin-8-stimulated polyphosphoinositide hydrolysis in human peripheral blood lymphocytes.
Topics: Calcium; Cells, Cultured; Chromatography, High Pressure Liquid; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Interleukin-8; Kinetics; Lymphocyte Activation; Lymphocytes; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phytohemagglutinins; Recombinant Proteins; Time Factors; Tumor Cells, Cultured | 1993 |
Measurement of receptor-activated phosphoinositide turnover in rat brain: nonequivalence of inositol phosphate and CDP-diacylglycerol formation.
Topics: Animals; Brain; Cytidine Diphosphate Diglycerides; Inositol; Inositol 1,4,5-Trisphosphate; Lithium; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface | 1993 |
Quantification of inositol phospholipid breakdown in isolated rat hepatocytes.
Topics: Animals; Diglycerides; Ethanol; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lithium; Liver; Male; Phosphatidic Acids; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Vasopressins | 1993 |
Cross-talk of second messengers during the systemic trauma response following burn injury: how, when, and where.
Topics: Animals; Burns; Calcium; Chromatography, Ion Exchange; Cyclic AMP; Glycerophosphates; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Male; Mice; Muscle Contraction; Second Messenger Systems | 1993 |
Noradrenaline stimulation unbalances the phosphoinositide cycle in rat cerebral cortical slices.
Topics: Animals; Calcium; Carbachol; Cell Membrane; Cerebral Cortex; Cytidine Diphosphate Diglycerides; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Norepinephrine; Nucleotidyltransferases; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositols; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley; Tritium | 1993 |
Evidence for receptor-specific regulation of the metabolism of the second messenger, inositol trisphosphate, in human endothelial cells.
Topics: Cells, Cultured; Chlorides; Chromatography, Ion Exchange; Endothelium, Vascular; Histamine; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isomerism; Kinetics; Lithium; Lithium Chloride; Models, Biological; Second Messenger Systems; Thrombin; Time Factors; Umbilical Veins | 1993 |
The effect of aldosterone on phospholipid and phosphoinositide metabolism in rat submandibular gland.
Topics: Aldosterone; Animals; Inositol; Inositol 1,4,5-Trisphosphate; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Submandibular Gland | 1993 |
Nucleus-associated phosphorylation of Ins(1,4,5)P3 to InsP6 in Dictyostelium.
Topics: Adenosine Triphosphate; Animals; Cell Nucleus; Chromatography, High Pressure Liquid; Cytosol; Dictyostelium; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Phosphates; Phosphorus Radioisotopes; Phosphorylation; Phytic Acid; Tritium | 1995 |
Stimulatory effect of hormonal signaling factors on (Ca(2+)-Mg2+)-ATPase activity in rat liver plasma membranes: cross talk with regucalcin.
Topics: Animals; Bucladesine; Ca(2+) Mg(2+)-ATPase; Calcium-Binding Proteins; Carboxylic Ester Hydrolases; Cell Membrane; Enzyme Activation; Guanosine Triphosphate; Inositol; Inositol 1,4,5-Trisphosphate; Intracellular Signaling Peptides and Proteins; Liver; Male; Polysaccharides; Rats; Rats, Wistar; Sulfotransferases | 1995 |
Thyroid-stimulating hormone rapidly stimulates inositol polyphosphate formation in FRTL-5 thyrocytes without activating phosphoinositidase C.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line; Cyclic AMP; Enzyme Activation; GTP-Binding Proteins; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Phosphoric Diester Hydrolases; Rats; Thyroid Gland; Thyrotropin | 1996 |
Insect adipokinetic hormone stimulates inositol phosphate metabolism: roles for both Ins(1,4,5)P3 and Ins(1,3,4,5)P4 in signal transduction?
Topics: Animals; Cell-Free System; Fat Body; Grasshoppers; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Insect Hormones; Kinetics; Male; Oligopeptides; Pyrrolidonecarboxylic Acid; Signal Transduction; Tritium | 1996 |
The inositol 1,4,5-trisphosphate 6-kinase of Schizosaccharomyces pombe.
Topics: Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Cytosol; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Molecular Weight; Phosphotransferases (Alcohol Group Acceptor); Schizosaccharomyces | 1997 |
Altered phospholipid metabolism in sodium butyrate-induced differentiation of C6 glioma cells.
Topics: Acylation; Animals; Arachidonic Acid; Butyrates; Butyric Acid; Calcium; Chloroform; Glioma; Glutamate-Ammonia Ligase; Glycerol; Histamine; Hydrolysis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phospholipids; Proteins; Rats; Thymidine; Tritium; Tumor Cells, Cultured | 1997 |
Lithium blocks cell cycle transitions in the first cell cycles of sea urchin embryos, an effect rescued by myo-inositol.
Topics: Animals; Cell Cycle; Embryo, Nonmammalian; Female; Fertilization; G2 Phase; Inositol; Inositol 1,4,5-Trisphosphate; Lithium Chloride; Male; Metaphase; Microinjections; Mitosis; Nuclear Envelope; Phosphatidylinositols; Sea Urchins; Second Messenger Systems; Stereoisomerism; Teratogens | 1997 |
Studies of inositol phosphate export from neuronal tissue in vitro.
Topics: Animals; Carbachol; Cerebral Cortex; Hippocampus; Humans; In Vitro Techniques; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Neuroblastoma; Neurons; Rats; Rats, Wistar; Sodium; Tumor Cells, Cultured | 1997 |
Inositol 1,4,5-trisphosphate turnover enzymes--activities and subcellular distribution in hepatocarcinogenesis.
Topics: Animals; Cell Compartmentation; Endosomes; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Polyphosphate 5-Phosphatases; Liver Neoplasms; Phosphoric Monoester Hydrolases; Phosphotransferases (Alcohol Group Acceptor); Precancerous Conditions; Rats; Subcellular Fractions | 1997 |
Disruption by lithium of phosphoinositide signalling in cerebellar granule cells in primary culture.
Topics: Animals; Carbachol; Cells, Cultured; Cerebellum; Diglycerides; Extracellular Space; Inositol; Inositol 1,4,5-Trisphosphate; Lithium; Muscarinic Agonists; Neurons; Phosphatidylinositols; Potassium Chloride; Rats; Signal Transduction | 1998 |
Estrogens cause rapid activation of IP3-PKC-alpha signal transduction pathway in HEPG2 cells.
Topics: Carcinoma, Hepatocellular; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Fulvestrant; Genistein; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Isoenzymes; Progesterone; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Tumor Cells, Cultured | 1998 |
Phosphatidylinositol and inositol involvement in Alzheimer amyloid-beta fibril growth and arrest.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cattle; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Peptide Fragments; Phosphatidylinositols; Plaque, Amyloid; Protein Conformation; Time Factors | 1998 |
Inositol hexakisphosphate in Schizosaccharomyces pombe: synthesis from Ins(1,4,5)P3 and osmotic regulation.
Topics: Homeostasis; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isomerism; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Osmolar Concentration; Phosphotransferases; Phytic Acid; Schizosaccharomyces; Tritium | 1998 |
Hypoxia inhibits the synthesis of phosphoinositides in the rabbit carotid body.
Topics: Animals; Carotid Body; Hypoxia; Inositol; Inositol 1,4,5-Trisphosphate; Lithium Chloride; Phosphatidylinositols; Rabbits; Rats; Rats, Wistar; Second Messenger Systems; Tritium; Type C Phospholipases | 1999 |
Receptor phosphorylation does not mediate cross talk between muscarinic M(3) and bradykinin B(2) receptors.
Topics: Animals; Atropine; Bradykinin; Calcium; CHO Cells; Cricetinae; Gene Expression; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Methacholine Chloride; Muscarinic Agonists; Muscarinic Antagonists; Phosphorylation; Receptor Cross-Talk; Receptor, Bradykinin B2; Receptor, Muscarinic M3; Receptors, Bradykinin; Receptors, Muscarinic; Recombinant Proteins; Signal Transduction; Transfection; Tritium; Type C Phospholipases | 1999 |
Calcium-dependent activation of phospholipase C by mechanical distension in renin-expressing As4.1 cells.
Topics: Animals; Calcium; Cell Line; Cytosol; Enzyme Activation; Estrenes; Extracellular Space; Fluorescent Dyes; Fura-2; Gadolinium; Inositol; Inositol 1,4,5-Trisphosphate; Ion Channels; Kidney; Mice; Mice, Transgenic; Phosphodiesterase Inhibitors; Pyrrolidinones; Renin; Ryanodine; Second Messenger Systems; Signal Transduction; Stress, Mechanical; Type C Phospholipases | 2000 |
2-O-(2-Aminoethyl)-myo-inositol 1,4,5-trisphosphate as a novel ligand for conjugation: physicochemical properties and synthesis of a new Ins(1,4,5)P(3) affinity matrix.
Topics: Amines; Biosensing Techniques; Calcium; Chromatography, Affinity; Hepatocytes; Humans; Hydrogen-Ion Concentration; Inositol; Inositol 1,4,5-Trisphosphate; Kinetics; Ligands; Models, Molecular; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phosphorus Isotopes; Potentiometry; Protein Binding; Protons | 2004 |
Functional coupling of chromogranin with the inositol 1,4,5-trisphosphate receptor shapes calcium signaling.
Topics: Animals; Calcium; Calcium Channels; Calcium Signaling; Chromogranins; Endoplasmic Reticulum; Inositol; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; PC12 Cells; Rats; Receptors, Cytoplasmic and Nuclear | 2004 |
The mood stabilizer valproate inhibits both inositol- and diacylglycerol-signaling pathways in Caenorhabditis elegans.
Topics: Acetylcholine; Animals; Antimanic Agents; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Defecation; Diglycerides; Inositol; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Muscle Contraction; Mutation; Ovulation; Phosphatidylinositol 4,5-Diphosphate; Signal Transduction; Valproic Acid | 2008 |
Sodium/myo-inositol cotransporter 1 and myo-inositol are essential for osteogenesis and bone formation.
Topics: Aging; Animals; Bone and Bones; Cell Count; Cell Differentiation; Cell Line; Embryo, Mammalian; Gene Deletion; Inositol; Inositol 1,4,5-Trisphosphate; Intracellular Space; Mesenchymal Stem Cells; Mice; Organ Size; Osteoblasts; Osteogenesis; Osteoporosis; Symporters; Transcription, Genetic | 2011 |
Measurement of phospholipase C by monitoring inositol phosphates using [³H]inositol-labeling protocols in permeabilized cells.
Topics: Calcium; Cell Membrane Permeability; HL-60 Cells; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Tritium; Type C Phospholipases | 2005 |
Resolution of orthogonally protected myo-inositols with novozym 435 providing an enantioconvergent pathway to Ac2PIM1.
Topics: Enzymes, Immobilized; Fungal Proteins; Inositol; Inositol 1,4,5-Trisphosphate; Lipase; Molecular Structure; Stereoisomerism | 2014 |
Differential Regulation of Multiple Steps in Inositol 1,4,5-Trisphosphate Signaling by Protein Kinase C Shapes Hormone-stimulated Ca2+ Oscillations.
Topics: Animals; Calcium; Calcium Signaling; Cell Membrane; Endoplasmic Reticulum; Hepatocytes; Hormones; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Protein Kinase C; Rats; Signal Transduction | 2015 |
IP3 accumulation and/or inositol depletion: two downstream lithium's effects that may mediate its behavioral and cellular changes.
Topics: Animals; Antimanic Agents; Autophagy; Behavior, Animal; Brain; Glycogen Synthase Kinase 3; Inositol; Inositol 1,4,5-Trisphosphate; Lithium Chloride; Mice; Mice, Inbred Strains; Mice, Knockout; Phosphatidylinositols; Phosphoric Monoester Hydrolases; RNA, Messenger; Symporters | 2016 |
CREB regulates the expression of type 1 inositol 1,4,5-trisphosphate receptors.
Topics: Calcium; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Humans; Inositol; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors | 2021 |
Structural and functional conservation of the activating Ca
Topics: Binding Sites; Calcium; Calcium Signaling; Inositol; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum | 2022 |