inositol and cysteine

inositol has been researched along with cysteine in 175 studies

Research

Studies (175)

TimeframeStudies, this research(%)All Research%
pre-19907 (4.00)18.7374
1990's14 (8.00)18.2507
2000's71 (40.57)29.6817
2010's74 (42.29)24.3611
2020's9 (5.14)2.80

Authors

AuthorsStudies
Koller, E; Koller, F1
Agathos, SN; Demain, AL2
Litjens, JB; van der Horst, CJ1
Brygier, J1
Bothwell, TH1
Bowen, ST; Chow, VH; Grigliatti, TA; Lebherz, HG; Poon, MC1
Hamilton, GA; Reddy, CC1
Aharonowitz, Y; Bewley, CA; Cohen, G; Davies, J; Dwyer, TJ; Fahey, RC; Faulkner, DJ; Horn, R; Newton, GL1
Spies, HS; Steenkamp, DJ1
Hatamori, N; Hayashi, Y; Hirohata, T; Kasuga, M; Mimoto, H; Mizoguchi, Y; Morita, S; Nakaoka, T; Yoshida, H; Yun, S1
Aharonowitz, Y; Arnold, K; Cohen, G; Davies, J; Davis, C; Delcardayre, SB; Fahey, RC; Newton, GL; Price, MS; Sherrill, C1
Duine, JA; Misset-Smits, M; Sakuda, S; van Ophem, PW1
Bornemann, C; Jardine, MA; Spies, HS; Steenkamp, DJ1
Duine, JA; Jörnvall, H; Norin, A; Persson, B; Piersma, SR; Van Ophem, PW1
Davis, C; Fahey, RC; Newton, GL; Unson, MD1
Anderberg, SJ; Fahey, RC; Newton, GL1
Aguilera, JA; Anderberg, SJ; Av-Gay, Y; delCardayre, SB; Fahey, RC; Newton, GL; Oh, NN; Unson, MD1
Arnold, KF; Davis, CE; Fahey, RC; Newton, GL; Unson, MD1
Mann, KJ; Medof, ME; Pickett, S; Rosenberry, TL; Sambamurti, K; Sevlever, D1
Duine, JA1
Av-Gay, Y; Fahey, RC; Newton, GL2
Fahey, RC2
Aharonowitz, Y; Buttner, MJ; Cohen, G; Molle, V; Paget, MS1
Gammon, DW; Jardine, MA; Nkambule, CM; Spies, HS; Steenkamp, DJ1
Bewley, CA; Kovác, P; Nicholas, GM1
Fahey, RC; Newton, GL; Sareen, D; Steffek, M1
Bliss, RL; Hecht, SS; Kenney, PM; McIntee, EJ; Upadhyaya, P; Wang, M1
Vorholt, JA1
Fahey, RC; Koledin, T; Newton, GL1
Av-Gay, Y; Fahey, RC; Ko, M; Martinez, GJ; Newton, GL; Rawat, M1
Fahey, RC; Newton, GL2
Bewley, CA; Eckman, LL; Gonzalez, S; Knapp, S; Myers, DS1
Bertozzi, CR; Leary, JA; Leavell, MD; Leigh, CD; Mougous, JD; Riley, LW; Senaratne, RH; Williams, SJ1
Buchmeier, NA; Fahey, RC; Koledin, T; Newton, GL1
Bewley, CA; Mahadevan, J; Nicholas, GM1
Av-Gay, Y; Billman-Jacobe, H; Kovacevic, S; Rawat, M1
Av-Gay, Y; Fahey, RC; Gorovitz, B; Koledin, T; Newton, GL; Rawat, M1
Bewley, CA; Eckman, LL; Kovác, P; Nicholas, GM; Otero-Quintero, S1
Gammon, DW; Hunter, R; Mudzunga, TT; Steenkamp, DJ1
Blanchard, JS; Steenkamp, DJ; Vogt, RN; Zheng, R1
Blanchard, JS; Roderick, SL; Vetting, MW; Yu, M1
Av-Gay, Y; Fahey, RC; Newton, GL; Steffek, M1
Buchmeier, NA; Fahey, RC; Newton, GL; Sareen, D1
Baker, EN; Knijff, R; McCarthy, AA; Peterson, NA1
Steenkamp, DJ; Vogt, RN1
Lee, S; Rosazza, JP1
Av-Gay, Y; Bancroft, GJ; Daffe, M; Dinadayala, P; Kendall, SL; McAlister, MS; McDonald, NQ; Movahedzadeh, F; Murray-Rust, J; Norman, RA; Rison, SC; Russell, DG; Smith, DA; Stoker, NG1
Hayward, D; van Helden, P; Wiid, I1
Av-Gay, Y; Fahey, RC; Newton, G; Rawat, M; Steffek, M; Uppal, M1
Coldham, NG; Gordon, SV; Hewinson, RG; Keating, L; Parish, T; Wheeler, PR; Wooff, EE1
Fahey, RC; Newton, GL; Ta, P1
Blanchard, JS; Rendle, PM; Vetting, MW; Yu, M1
Che, Y; Feng, J; Kalinowski, J; Liu, L; Liu, SJ; Milse, J; Qi, SW; Rückert, C; Shen, XH; Yin, YJ1
Cha, CJ; Park, JH; Roe, JH1
Auzanneau, FI; Hand, CE; Honek, JF1
Av-Gay, Y; Fahey, RC; Ko, M; Newton, GL; Ta, P1
Av-Gay, Y; Ung, KS1
Fahey, RC; Newton, GL; Sareen, D; Ta, P1
Nguyen, L; Thompson, CJ1
Bewley, CA; Fahey, RC; Gutierrez-Lugo, MT; Newton, GL1
Bzymek, KP; Fahey, RC; Newton, GL; Ta, P2
Buchmeier, N; Fahey, RC1
Bewley, CA; Metaferia, BB; Ray, S; Smith, JA1
Chen, Z; Huang, Q; Li, X; Li, Y; Xu, S; Zhang, H; Zhang, Y1
Av-Gay, Y; Rawat, M1
Bergeron, H; Lau, PC; Lee, S; Rosazza, JP1
Chang, WR; Feng, J; Li, M; Liu, SJ; Wang, F; Wang, R; Yin, YJ; Zhang, HM; Zhang, JP1
Gammon, DW; Oscarson, S; Slättegård, R1
Av-Gay, Y; Johnson, T; Miller, CC; Rawat, M1
Av-Gay, Y; Cadiz, V; Johnson, C; Rawat, M1
Blanchard, JS; Fan, F; Luxenburger, A; Painter, GF1
Bhave, DP; Carroll, KS; Muse, WB1
Bewley, CA; Fetterolf, BJ; Gutierrez-Lugo, MT; Metaferia, BB; Moravec, M; Ray, S; Shazad-Ul-Hussan, S; Smith, JA1
Hamilton, CJ; Jothivasan, VK; Rowan, AS; Stewart, MJ; Wagg, J1
Park, JH; Roe, JH1
Fahey, RC; Fenical, W; Jensen, PR; Macmillan, JB; Newton, GL1
Alland, D; Attarian, R; Av-Gay, Y; Chen, B; Colangeli, R; Hazbón, MH; Jacobs, WR; Liu, W; Liu, Z; Sacchettini, JC; Vilchèze, C1
Fahey, RC; Johnson, T; Newton, GL; Rawat, M1
Buchmeier, N; Fahey, RC; Newton, GL1
Hamilton, CJ; Jothivasan, VK1
Blanchard, JS; Fan, F; Tremblay, LW; Vetting, MW1
Hecht, SS; Kassie, F; Lahti, D; Matise, I; Negia, M; Pan, Y; Scherber, R; Upadhyaya, P1
Bonner, A; Finlay, RM; Hamilton, CJ; Stewart, MJ1
De Galan, S; Gil, JA; Letek, M; Mateos, LM; Messens, J; Ordóñez, E; Roos, G; Van Belle, K; Wyns, L1
Blanchard, JS; Fan, F1
Baker, H; Bewley, CA; Boshoff, H; Gutierrez-Lugo, MT; Shiloach, J1
Hatsukami, DK; Hecht, SS; Kassie, F1
Blanchard, JS; Fan, F; Frantom, PA; Vetting, MW1
Gammon, DW; Hunter, R; Marakalala, MJ; Mavumengwana, V; Mudzunga, TT; Munyololo, M; Steenkamp, DJ1
Ajayi, K; Knapp, S; Lapo, RC; Thakur, VV1
Endalew, A; Hecht, SS; Kassie, F; Luo, X; Melkamu, T; Upadhyaya, P1
Claiborne, A; Dos Santos, PC; Hamilton, CJ; Holder, RC; Newton, GL; Paige, C; Parsonage, D; Redinbo, MR; Reid, SD; Wallace, BD1
Jiang, CY; Jin, JH; Liu, SJ; Luo, YM; Wang, BJ; Yin, YJ1
Buchmeier, N; Fahey, RC; Newton, GL; Rawat, M; Ta, P1
Av-Gay, Y; Gómez-Velasco, A; Jacobs, WR; Vilchèze, C; Xu, X1
Hernick, M; Huang, X; Kocabas, E1
Buchmeier, N; Fahey, RC; La Clair, JJ; Newton, GL1
Av-Gay, Y; Barnes, SW; Glynne, RJ; Jacobs, WR; Larsen, MH; Vilchèze, C; Walker, JR1
Ayling, LJ; Cooper, DM; Delint-Ramirez, I; Hammond, GR; Hammond, GV; Willoughby, D1
Chung, CC; Hung, SC; Padiyar, LT; Zulueta, MM1
Fahey, RC; Leung, SS; Newton, GL; Rawat, M; Wakabayashi, JI1
Chi, HW; Chin, DH; Huang, CC1
Fahey, RC; Gushiken, M; Holden, D; Lo, K; Newton, GL; Rawat, M; Upton, H1
Eastwood, H; Jardine, A; Lamprecht, DA; Muneri, NO; Naidoo, KJ; Strauss, E1
Buts, L; Foloppe, N; Mateos, LM; Messens, J; Nilsson, L; Rawat, M; Roos, G; Van Belle, K; Van Laer, K; van Nuland, NA; Vertommen, D; Wahni, K1
McConnell, MS; Nguyen, HM; Yu, F1
Antelmann, H; Hamilton, CJ1
Collet, JF; Dziewulska, AM; Fislage, M; Hbeddou, A; Mateos, LM; Messens, J; Tamu Dufe, V; Van Laer, K; Versées, W; Wahni, K1
Hernick, M1
Gammon, DW; Naidoo, KJ; Rogers, IL1
Liu, YB; Long, MX; Lu, ZQ; Shen, XH; Si, MR; Wang, Y; Yin, YJ; Zhang, L1
Baker, B; Hiten, NF; Pietersen, RD; Sao Emani, C; van Helden, PD; Viljoen, AJ; Wiid, IJ; Williams, MJ1
Hartman, T; Jacobs, WR; Vilchèze, C; Weinrick, B1
Antelmann, H; Bäsell, K; Becher, D; Busche, T; Chi, BK; Clermont, L; Kalinowski, J; Messens, J; Persicke, M; Seibold, GM; Van Laer, K1
Hernick, M; Huang, X1
Kathiravan, MK; Nilewar, SS1
Hugo, M; Messens, J; Radi, R; Reyes, AM; Trujillo, M; Van Laer, K; Vertommen, D1
Bhaskar, A; Bhave, D; Carroll, KS; Chandra, P; Chawla, M; Kumar, D; Mehta, M; Parikh, P; Singh, A1
Argon, Y; Dersh, D; Eletto, D; Gidalevitz, T1
Chaudhry, MT; Chen, C; Liu, YB; Shen, XH; Si, MR; Wang, Y; Zhang, L1
Liu, W; Wang, M; Xu, D; Zhang, Q; Zhao, Q1
Melançon, CE1
Dairi, T; Matsui, T; Nakajima, S; Satoh, Y; Yanashima, K1
Bochud, A; Conzelmann, A1
Gazak, R; Janata, J; Kadlcik, S; Kamenik, Z; Koberska, M; Kopecky, J; Najmanova, L; Novak, P; Novotna, J; Plhackova, K; Radojevic, B; Ulanova, D1
Erdogan, H; Messens, J; Pedre, B; Tossounian, MA; Van Molle, I; Vertommen, D; Wahni, K1
Erdogan, H; Mateos, LM; Messens, J; Pedre, B; Turell, L; Van Molle, I; Vertommen, D; Villadangos, AF; Wahni, K1
Corkran, HM; Dasyam, N; Field, JJ; Harvey, JE; Riordan, SW; Stocker, BL; Teesdale-Spittle, PH; Timmer, MS1
Ikeda, H; Nagamitsu, T; Shin-Ya, K; Tomoda, H1
Liu, W; Wang, M; Zhao, Q1
Mehta, M; Rajmani, RS; Singh, A1
Adamson, JH; Av-Gay, Y; Bach, H; Chinta, KC; Cumming, BM; Eoh, H; Glasgow, JN; Gomez-Velasco, A; Guidry, L; Lamprecht, DA; Mazorodze, JH; Reddy, VP; Rhee, K; Richard-Greenblatt, M; Saini, V; Steyn, AJC1
Lawrence, R; Patel, ND; Peteroy-Kelly, MA1
Gao, F; Kang, Y; Li, M; Shen, X; Si, M; Su, T; Wang, T; Zhao, C1
Chen, C; Lin, J; Liu, Y; Pan, J; Shen, X; Si, M; Yang, X; Yin, Y1
Gulati, M; Hageman, S; Nobile, CJ; Rawat, M; Vargas, D1
Hamilton, CJ; Messens, J; Sharma, SV; Van Laer, K1
Chen, K; Shen, X; Si, M; Wei, D; Xiao, H; Yang, X; Zhang, B; Zhao, C1
Balakrishna, AM; Grüber, G; Kumar, A; Manimekalai, MSS; Nartey, W1
Lin, HC; Ma, L; Neu, J; Zhou, P1
Blanco Capurro, JI; González Lebrero, MC; Hopkins, CW; Marti, MA; Pierdominici Sottile, G; Roitberg, AE1
Alvarez, HM; Dávila Costa, JS; Leichert, L; Silva, RA1
De Armas, MI; Messens, J; Pedre, B; Radi, R; Reyes, AM; Tossounian, MA; Trujillo, M1
Gu, G; Guo, J; Guo, Y; Guo, Z; Wang, L1
Antelmann, H; Becher, D; Bernhardt, J; Busche, T; Hell, R; Hillion, M; Kalinowski, J; Maaß, S; Rawat, M; Rossius, M; Rückert, C; Wirtz, M1
Adrian, L; Antelmann, H; Astolfi Rosado, L; Becher, D; Bernhardt, J; Hell, R; Hillion, M; Imber, M; Loi, VV; Maaß, S; Messens, J; Pedre, B; Saleh, M; Weise, C; Wirtz, M1
Aboushleib, HM; Bahey-El-Din, M; Kassem, MA; Zeitoun, H1
Baker, B; Sao Emani, C; Taylor, MJC; Van Helden, PD; Wiid, IJ; Williams, MJ1
Andreana, PR; Patel, K; Song, F1
Comini, MA; Salinas, G1
Grüber, G; Kumar, A; Subramanian Manimekalai, MS1
Antelmann, H; Linzner, N; Loi, VV; Tung, QN1
Barman, D; Beuming, T; Burns-Huang, K; Gold, B; Ioerger, T; Javidnia, P; Jiang, X; Li, H; Ling, Y; Liu, G; Mu, R; Nathan, CF; Negri, A; Oren, DA; Rhee, KY; Roberts, J; Sacchettini, JC; Somersan-Karakaya, S; Vendome, J; Wang, H; Warren, JD; Warrier, T; Wu, J; Zhang, X1
Gazak, R; Janata, J; Kadlcik, S; Kamenik, Z; Najmanova, L1
Baker, B; Sao Emani, C; Wiid, IJ; Williams, MJ1
Baker, B; Carolis, C; Sao Emani, C; Taylor, MJC; Van Helden, PD; Wiid, IJ; Williams, MJ1
Chen, C; Chen, K; Li, G; Pan, J; Si, M; Su, T; Zhang, B1
Antelmann, H; Imber, M; Pietrzyk-Brzezinska, AJ1
Baker, B; Gallant, JL; Sao Emani, C; Wiid, IJ1
Liu, HH; Liu, YJ; Ren, YH; Sun, WJ; Wang, FQ; Wang, L; Wei, DZ1
Che, C; Chen, C; Gong, Z; Li, G; Li, X; Liu, J; Si, M; Yang, G1
Buts, L; Khanh Truong, AC; Leermakers, M; Mateos, LM; Messens, J; Mourenza, Á; Tossounian, MA; Vertommen, D; Volkov, AN; Wahni, K1
Heine, T; Lienkamp, AC; Tischler, D1
Che, C; Gong, Z; Li, X; Liu, Y; Si, M; Yang, G; Zhong, J1
Aung, HL; Cook, GM; Dickerhof, N; Forrester, L; Hampton, MB; Kettle, AJ; Messens, J; Parker, HA; Ryburn, H; Smyth, L1
Al-Nayal, A; Carapito, C; Dahl, C; Heintz, D; Hirschler, A; Ismail, W; Mahmoud, H; Maurer, L; Sangal, V; Van Dorsselaer, A; Villette, C; Zumsteg, J1
Chen, K; Li, X; Liu, Y; Si, M; Su, T; Yu, X; Zhang, X1
Castillo Arteaga, RD; Garrido, LM; Gross, H; Gust, B; Helmle, I; Padilla, G; Pedre, B1
Fan, LX; Gao, AH; Jiang, HN; Jiang, KL; Li, J; Lin, LL; Liu, CM; Nie, LT; Tan, MJ; Wang, XY; Xu, L; Zhang, KZ; Zhang, QQ; Zhou, YB1
Cappoen, D; Lenders, S; Osipov, EM; Pang, L; Piller, T; Rozenski, J; Strelkov, SV; Van Aerschot, A; Weeks, SD1

Reviews

20 review(s) available for inositol and cysteine

ArticleYear
The control of iron absorption.
    British journal of haematology, 1968, Volume: 14, Issue:5

    Topics: Absorption; Anemia, Hypochromic; Ascorbic Acid; Cysteine; Erythropoiesis; Ferritins; Gastric Juice; Hemochromatosis; Humans; Inositol; Intestinal Mucosa; Iron; Pancreatic Juice; Succinates; Transferrin

1968
Thiols in formaldehyde dissimilation and detoxification.
    BioFactors (Oxford, England), 1999, Volume: 10, Issue:2-3

    Topics: Aldehyde Oxidoreductases; Cysteine; Disaccharides; Formaldehyde; Glutathione; Glycopeptides; Gram-Positive Bacteria; Inactivation, Metabolic; Inositol; Mycobacterium; Pyrazoles; Sulfhydryl Compounds

1999
Novel thiols of prokaryotes.
    Annual review of microbiology, 2001, Volume: 55

    Topics: Cysteine; Disaccharides; Ergothioneine; Glutathione; Glycopeptides; Inositol; Mesna; Models, Chemical; Phosphothreonine; Prokaryotic Cells; Pyrazoles; Sulfhydryl Compounds

2001
Cofactor-dependent pathways of formaldehyde oxidation in methylotrophic bacteria.
    Archives of microbiology, 2002, Volume: 178, Issue:4

    Topics: Cysteine; Disaccharides; Formaldehyde; Glutathione; Glycopeptides; Inositol; Methanol; Oxidation-Reduction; Proteobacteria; Pyrazoles; Sulfhydryl Compounds; Tetrahydrofolates

2002
Mycothiol biochemistry.
    Archives of microbiology, 2002, Volume: 178, Issue:6

    Topics: Aldehyde Oxidoreductases; Amidohydrolases; Cysteine; Disaccharides; Glycopeptides; Inactivation, Metabolic; Inositol; Mycobacterium tuberculosis; Oxidation-Reduction; Pyrazoles; Sulfhydryl Compounds

2002
Mycothiol-dependent proteins in actinomycetes.
    FEMS microbiology reviews, 2007, Volume: 31, Issue:3

    Topics: Actinobacteria; Amidohydrolases; Biosynthetic Pathways; Coenzymes; Cysteine; Glycopeptides; Inactivation, Metabolic; Inositol; Molecular Sequence Data; Mycobacterium tuberculosis; NADH, NADPH Oxidoreductases; Oxidation-Reduction

2007
Drug targets in mycobacterial sulfur metabolism.
    Infectious disorders drug targets, 2007, Volume: 7, Issue:2

    Topics: Antitubercular Agents; Biological Transport; Cysteine; Glutathione; Glycopeptides; Inositol; Methionine; Mycobacterium tuberculosis; NADPH Oxidases; Sulfates; Sulfotransferases; Sulfur

2007
Biosynthesis and functions of mycothiol, the unique protective thiol of Actinobacteria.
    Microbiology and molecular biology reviews : MMBR, 2008, Volume: 72, Issue:3

    Topics: Actinobacteria; Bacterial Proteins; Cysteine; Gene Expression Regulation, Bacterial; Glycopeptides; Inositol; Mutation

2008
Mycothiol: synthesis, biosynthesis and biological functions of the major low molecular weight thiol in actinomycetes.
    Natural product reports, 2008, Volume: 25, Issue:6

    Topics: Actinobacteria; Cysteine; Glycopeptides; Inositol; Molecular Structure; Molecular Weight; Sulfhydryl Compounds

2008
Chemoprevention of lung carcinogenesis in addicted smokers and ex-smokers.
    Nature reviews. Cancer, 2009, Volume: 9, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Budesonide; Clinical Trials as Topic; Cysteine; Humans; Inositol; Lung Neoplasms; Smoking; Thiocarbamates

2009
Structures and mechanisms of the mycothiol biosynthetic enzymes.
    Current opinion in chemical biology, 2009, Volume: 13, Issue:4

    Topics: Acetylesterase; Amidohydrolases; Bacterial Proteins; Cysteine; Glycopeptides; Glycosyltransferases; Inositol; Ligases; Models, Molecular; Mycobacterium tuberculosis

2009
Glutathione analogs in prokaryotes.
    Biochimica et biophysica acta, 2013, Volume: 1830, Issue:5

    Topics: Bacteria; Cysteine; Glutathione; Glycopeptides; Humans; Inositol; Molecular Weight; Oxygen; Prokaryotic Cells

2013
Mycothiol: a target for potentiation of rifampin and other antibiotics against Mycobacterium tuberculosis.
    Expert review of anti-infective therapy, 2013, Volume: 11, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Antitubercular Agents; Cysteine; Drug Delivery Systems; Drug Synergism; Enzyme Inhibitors; Glycopeptides; Humans; Inositol; Mycobacterium tuberculosis; Rifampin

2013
Mycothiol: a promising antitubercular target.
    Bioorganic chemistry, 2014, Volume: 52

    Topics: Antitubercular Agents; Cysteine; Glycopeptides; Inositol; Molecular Targeted Therapy; Mycobacterium tuberculosis

2014
Potential Nutrients for Preventing or Treating Bronchopulmonary Dysplasia.
    Paediatric respiratory reviews, 2017, Volume: 22

    Topics: Acetylcysteine; Antioxidants; Arginine; Bronchopulmonary Dysplasia; Citrulline; Cysteine; Fatty Acids, Unsaturated; Glutamine; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn; Infant, Premature; Inositol; Selenium; Vitamin A; Vitamin B Complex

2017
Chemistry and Redox Biology of Mycothiol.
    Antioxidants & redox signaling, 2018, 02-20, Volume: 28, Issue:6

    Topics: Cysteine; Glycopeptides; Inositol; Mycobacterium tuberculosis; Oxidants; Oxidation-Reduction; Oxidative Stress; Peroxidases; Sulfhydryl Compounds

2018
Application of genetically encoded redox biosensors to measure dynamic changes in the glutathione, bacillithiol and mycothiol redox potentials in pathogenic bacteria.
    Free radical biology & medicine, 2018, 11-20, Volume: 128

    Topics: Biosensing Techniques; Cysteine; Glucosamine; Glutathione; Glycopeptides; Green Fluorescent Proteins; Humans; Inositol; Mycobacterium tuberculosis; Oxidation-Reduction; Recombinant Fusion Proteins; Staphylococcus aureus

2018
Biosynthesis and incorporation of an alkylproline-derivative (APD) precursor into complex natural products.
    Natural product reports, 2018, 03-01, Volume: 35, Issue:3

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Benzodiazepines; Biological Products; Cysteine; Depsipeptides; Ergothioneine; Evolution, Molecular; Glycopeptides; Humans; Inositol; Lincomycin; Lincosamides; Molecular Structure

2018
Redox regulation by reversible protein S-thiolation in Gram-positive bacteria.
    Redox biology, 2019, Volume: 20

    Topics: Animals; Cysteine; Glucosamine; Glycopeptides; Gram-Positive Bacteria; Humans; Inositol; Models, Biological; Oxidation-Reduction; Protein Processing, Post-Translational; Structure-Activity Relationship; Sulfhydryl Compounds

2019
The role of low molecular weight thiols in Mycobacterium tuberculosis.
    Tuberculosis (Edinburgh, Scotland), 2019, Volume: 116

    Topics: Animals; Antitubercular Agents; Cysteine; Dipeptides; Enzyme Inhibitors; Enzymes; Ergothioneine; Glycopeptides; Humans; Inositol; Molecular Targeted Therapy; Molecular Weight; Mycobacterium tuberculosis; Sulfhydryl Compounds; Tuberculosis

2019

Other Studies

155 other study(ies) available for inositol and cysteine

ArticleYear
myo-inositol oxygenase from rat kidneys. Substrate-dependent oligomerization.
    European journal of biochemistry, 1990, Oct-24, Volume: 193, Issue:2

    Topics: Animals; Chromatography, Gel; Cysteine; Ferrous Compounds; Inositol; Inositol Oxygenase; Kidney; Kinetics; Oligopeptides; Oxygenases; Protein Conformation; Protein Denaturation; Rats

1990
Studies on in vivo inactivation of gramicidin S synthetase and its retardation.
    Canadian journal of microbiology, 1986, Volume: 32, Issue:3

    Topics: 2,4-Dinitrophenol; Amino Acid Isomerases; Bacillus; Bacterial Proteins; Cysteine; Dinitrophenols; Dithiothreitol; Energy Metabolism; Fructose; Glucose; Glycerol; Gramicidin; Half-Life; Inositol; Multienzyme Complexes; Oxidation-Reduction; Peptide Synthases; Sorbitol; Time Factors

1986
[Artificial insemination in turkeys and an investigation into a suitable diluent of turkey semen (author's transl)].
    Tijdschrift voor diergeneeskunde, 1972, Feb-15, Volume: 97, Issue:4

    Topics: Animals; Calcium Chloride; Cell Movement; Citrates; Cysteine; Female; Glucose; Glutamates; Hydrogen-Ion Concentration; Inositol; Insemination, Artificial; Magnesium; Male; Methods; Potassium Chloride; Pregnancy; Pregnancy, Animal; Preservation, Biological; Semen; Sodium; Spermatozoa; Staining and Labeling; Turkeys

1972
The pH dependence of oxygen equilibrium in chicken hemoglobins modified by para-mercuribenzoate.
    Biochimie, 1974, Volume: 56, Issue:5

    Topics: Amino Acid Sequence; Animals; Binding Sites; Chickens; Cysteine; Hemoglobins; Hydrogen-Ion Concentration; Inositol; Kinetics; Mercuribenzoates; Organophosphorus Compounds; Oxygen; Protein Conformation

1974
The hemoglobins of Artemia salina. I. Determination of phenotype by genotype and environment.
    Comparative biochemistry and physiology, 1969, Dec-01, Volume: 31, Issue:5

    Topics: Adaptation, Biological; Animals; Biological Evolution; Blood Protein Electrophoresis; Carbon Monoxide; Crustacea; Cysteine; Edetic Acid; Female; Genotype; Hemoglobins; Humans; Inositol; Iron; Male; Oxygen; Parthenogenesis; Phenotype; Sex Factors; Tryptophan

1969
Activation of homogeneous preparations of hog kidney myo-inositol oxygenase by quinolinic acid and ferrous ions.
    Biochemical and biophysical research communications, 1981, Jun-16, Volume: 100, Issue:3

    Topics: Animals; Cysteine; Enzyme Activation; Inositol; Inositol Oxygenase; Iron; Kidney; Kinetics; Oxygenases; Pyridines; Quinolinic Acid; Quinolinic Acids; Swine

1981
Gramicidin S synthetase stabilization in vivo.
    Annals of the New York Academy of Sciences, 1984, Volume: 434

    Topics: Amino Acid Isomerases; Amino Acids; Bacillus; Cysteine; Fructose; Glycerol; Inositol; Kinetics; Multienzyme Complexes; Oxidation-Reduction; Oxygen; Peptide Synthases; Sulfhydryl Compounds

1984
The structure of U17 isolated from Streptomyces clavuligerus and its properties as an antioxidant thiol.
    European journal of biochemistry, 1995, Jun-01, Volume: 230, Issue:2

    Topics: Antioxidants; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Cysteine; Disaccharides; Glycopeptides; Inositol; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Molecular Structure; Pyrazoles; Streptomyces; Sulfhydryl Compounds

1995
Thiols of intracellular pathogens. Identification of ovothiol A in Leishmania donovani and structural analysis of a novel thiol from Mycobacterium bovis.
    European journal of biochemistry, 1994, Aug-15, Volume: 224, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Disaccharides; Glycopeptides; Hydrolysis; Inositol; Leishmania donovani; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methylhistidines; Molecular Weight; Mycobacterium bovis; Mycobacterium tuberculosis; NADH, NADPH Oxidoreductases; Pyrazoles; Sulfhydryl Compounds

1994
[A case of prolonged liver injury caused by low dose of acetaminophen--the involvement of other multiple drugs such as Proheparum and Mazulene-S was considered in this drug-induced hepatitis].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1993, Volume: 90, Issue:11

    Topics: Acetaminophen; Adult; Azulenes; Bis-Trimethylammonium Compounds; Chemical and Drug Induced Liver Injury; Cysteine; Drug Combinations; Female; Humans; Inositol; Liver; Liver Extracts; Sesquiterpenes; Vitamin B 12

1993
Distribution of thiols in microorganisms: mycothiol is a major thiol in most actinomycetes.
    Journal of bacteriology, 1996, Volume: 178, Issue:7

    Topics: Actinomycetales; Coenzyme A; Cysteine; Disaccharides; Glycopeptides; Inositol; Molecular Structure; Pyrazoles; Sulfhydryl Compounds

1996
Mycothiol, 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D- myo-inositol, is the factor of NAD/factor-dependent formaldehyde dehydrogenase.
    FEBS letters, 1997, Jun-09, Volume: 409, Issue:2

    Topics: Aldehyde Oxidoreductases; Bacterial Proteins; Chromatography, High Pressure Liquid; Cysteine; Disaccharides; Glycopeptides; Inositol; NAD; Pyrazoles; Streptomyces; Sulfhydryl Compounds

1997
Biosynthesis of mycothiol: elucidation of the sequence of steps in Mycobacterium smegmatis.
    The Biochemical journal, 1997, Aug-01, Volume: 325 ( Pt 3)

    Topics: Acetates; Carbohydrate Conformation; Cysteine; Disaccharides; Glycopeptides; Inositol; Magnetic Resonance Spectroscopy; Mycobacterium; Pyrazoles; Substrate Specificity; Sulfhydryl Compounds

1997
Mycothiol-dependent formaldehyde dehydrogenase, a prokaryotic medium-chain dehydrogenase/reductase, phylogenetically links different eukaroytic alcohol dehydrogenases--primary structure, conformational modelling and functional correlations.
    European journal of biochemistry, 1997, Sep-01, Volume: 248, Issue:2

    Topics: Actinomycetales; Aldehyde Oxidoreductases; Amino Acid Sequence; Cysteine; Disaccharides; Fatty Acid Desaturases; Glycopeptides; Humans; Inositol; Models, Molecular; Molecular Sequence Data; Phylogeny; Protein Conformation; Pyrazoles; Sequence Homology, Amino Acid; Sulfhydryl Compounds

1997
An immunoassay for the detection and quantitative determination of mycothiol.
    Journal of immunological methods, 1998, May-01, Volume: 214, Issue:1-2

    Topics: Animals; Antibodies; Chromatography, High Pressure Liquid; Cysteine; Disaccharides; Enterococcus faecalis; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Female; Glycopeptides; Hemocyanins; Immunoglobulin G; Immunohistochemistry; Inositol; Mycobacterium; Pyrazoles; Rabbits; Sensitivity and Specificity; Serum Albumin, Bovine; Streptococcus mutans; Sulfhydryl Compounds

1998
Mycothiol biosynthesis and metabolism. Cellular levels of potential intermediates in the biosynthesis and degradation of mycothiol in mycobacterium smegmatis.
    The Journal of biological chemistry, 1998, Nov-13, Volume: 273, Issue:46

    Topics: Chromatography, High Pressure Liquid; Cysteine; Disaccharides; Glycopeptides; Inositol; Models, Chemical; Mycobacterium smegmatis; Pyrazoles; Sulfhydryl Compounds

1998
Characterization of Mycobacterium smegmatis mutants defective in 1-d-myo-inosityl-2-amino-2-deoxy-alpha-d-glucopyranoside and mycothiol biosynthesis.
    Biochemical and biophysical research communications, 1999, Feb-16, Volume: 255, Issue:2

    Topics: Culture Media; Cysteine; Disaccharides; Drug Resistance, Microbial; Genetic Complementation Test; Glucosides; Glycopeptides; Hydrogen Peroxide; Inositol; Isoniazid; Mutagenesis; Mycobacterium smegmatis; Pyrazoles; Rifampin; Sulfhydryl Compounds

1999
Improved methods for immunoassay of mycothiol.
    Journal of clinical microbiology, 1999, Volume: 37, Issue:7

    Topics: Animals; Antibodies; Antibody Specificity; Biotinylation; Cerebrospinal Fluid; Cysteine; Disaccharides; Enzyme-Linked Immunosorbent Assay; Glycopeptides; Humans; Indicators and Reagents; Inositol; Mycobacterium Infections, Nontuberculous; Mycobacterium smegmatis; Pyrazoles; Rabbits; Sensitivity and Specificity; Sulfhydryl Compounds; Urine

1999
Glycosylphosphatidylinositol-anchor intermediates associate with triton-insoluble membranes in subcellular compartments that include the endoplasmic reticulum.
    The Biochemical journal, 1999, Nov-01, Volume: 343 Pt 3

    Topics: Animals; Carbohydrate Sequence; Cell Fractionation; CHO Cells; Choline; Cricetinae; Cysteine; Endoplasmic Reticulum; Glucosamine; Glycosylphosphatidylinositols; HeLa Cells; Humans; Inositol; Intracellular Membranes; K562 Cells; Mannose; Membrane Proteins; Models, Chemical; Molecular Sequence Data; Polyethylene Glycols; Radioisotope Dilution Technique; Sulfur Radioisotopes; Tritium; Uridine Diphosphate N-Acetylglucosamine

1999
A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase.
    Biochemistry, 2000, Sep-05, Volume: 39, Issue:35

    Topics: Aldehyde Oxidoreductases; Alkylation; Amidohydrolases; Amino Acid Sequence; Bacterial Proteins; Cysteine; Disaccharides; Escherichia coli; Glycopeptides; Hydrolysis; Inactivation, Metabolic; Inositol; Molecular Sequence Data; Mycobacterium smegmatis; Mycobacterium tuberculosis; Pyrazoles; Sequence Homology, Amino Acid; Sulfhydryl Compounds

2000
N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesis.
    Journal of bacteriology, 2000, Volume: 182, Issue:24

    Topics: Acetylation; Acetylglucosamine; Amidohydrolases; Bacterial Proteins; Cysteine; Disaccharides; Glycopeptides; Inositol; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; Pyrazoles; Sulfhydryl Compounds

2000
Defining the disulphide stress response in Streptomyces coelicolor A3(2): identification of the sigmaR regulon.
    Molecular microbiology, 2001, Volume: 42, Issue:4

    Topics: Amino Acid Sequence; Bacterial Proteins; Consensus Sequence; Cysteine; Databases, Genetic; Disaccharides; Disulfides; DNA-Directed RNA Polymerases; Gene Expression Regulation, Bacterial; Genes, Bacterial; Glutaredoxins; Glycopeptides; Inositol; Molecular Sequence Data; Operon; Oxidoreductases; Promoter Regions, Genetic; Proteins; Pyrazoles; Regulon; Ribosomes; RNA, Bacterial; Sequence Alignment; Sigma Factor; Streptomyces; Sulfhydryl Compounds

2001
Synthesis of mycothiol, 1D-1-O-(2-[N-acetyl-L-cysteinyl]amino-2-deoxy-alpha-D-glucopyranosyl)-myo-inositol, principal low molecular mass thiol in the actinomycetes.
    Bioorganic & medicinal chemistry, 2002, Volume: 10, Issue:4

    Topics: Actinomycetales; Cysteine; Disaccharides; Glycopeptides; Inositol; Molecular Weight; Mycobacterium smegmatis; Nuclear Magnetic Resonance, Biomolecular; Pyrazoles; Sulfhydryl Compounds

2002
Total synthesis and proof of structure of mycothiol bimane.
    Journal of the American Chemical Society, 2002, Apr-10, Volume: 124, Issue:14

    Topics: Bridged Bicyclo Compounds, Heterocyclic; Circular Dichroism; Cysteine; Disaccharides; Glycopeptides; Inositol; Pyrazoles; Sulfhydryl Compounds

2002
ATP-dependent L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, mycothiol biosynthesis enzyme MshC, is related to class I cysteinyl-tRNA synthetases.
    Biochemistry, 2002, Jun-04, Volume: 41, Issue:22

    Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Base Sequence; Cysteine; Databases, Nucleic Acid; Disaccharides; Glycopeptides; Inositol; Ligases; Molecular Sequence Data; Mycobacterium smegmatis; Mycobacterium tuberculosis; Pyrazoles; Sulfhydryl Compounds

2002
Inhibition of lung tumorigenesis in A/J mice by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine and myo-inositol, individually and in combination.
    Carcinogenesis, 2002, Volume: 23, Issue:9

    Topics: Animals; Antineoplastic Agents; Carcinogenicity Tests; Cell Transformation, Neoplastic; Cysteine; Disease Models, Animal; Female; Inositol; Isothiocyanates; Lung Neoplasms; Mice; Thiocarbamates

2002
Identification of the mycothiol synthase gene (mshD) encoding the acetyltransferase producing mycothiol in actinomycetes.
    Archives of microbiology, 2002, Volume: 178, Issue:5

    Topics: Acetyltransferases; Amidohydrolases; Amino Acid Sequence; Bacterial Proteins; Cloning, Molecular; Cosmids; Cysteine; Disaccharides; DNA Transposable Elements; Glycopeptides; Inositol; Molecular Sequence Data; Mutagenesis, Insertional; Mutation; Mycobacterium smegmatis; Pyrazoles; Sequence Homology, Amino Acid; Sulfhydryl Compounds

2002
Mycothiol-deficient Mycobacterium smegmatis mutants are hypersensitive to alkylating agents, free radicals, and antibiotics.
    Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:11

    Topics: Alkylating Agents; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Cysteine; Disaccharides; DNA Transposable Elements; DNA, Bacterial; Free Radicals; Genetic Complementation Test; Glycopeptides; Inositol; Ligases; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Mycobacterium smegmatis; Oxidative Stress; Phenotype; Pyrazoles; Sulfhydryl Compounds

2002
Shortcut to mycothiol analogues.
    Organic letters, 2002, Nov-28, Volume: 4, Issue:24

    Topics: Amidohydrolases; Antitubercular Agents; Cysteine; Disaccharides; Drug Design; Glycopeptides; Inositol; Molecular Structure; Mycobacterium tuberculosis; Pyrazoles; Sulfhydryl Compounds

2002
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach.
    Proceedings of the National Academy of Sciences of the United States of America, 2002, Dec-24, Volume: 99, Issue:26

    Topics: Cysteine; Disaccharides; Genetic Engineering; Glycopeptides; Inositol; Mass Spectrometry; Mycobacterium smegmatis; Mycobacterium tuberculosis; Pyrazoles; Sulfates; Sulfhydryl Compounds; Sulfoglycosphingolipids; Sulfur Isotopes

2002
Association of mycothiol with protection of Mycobacterium tuberculosis from toxic oxidants and antibiotics.
    Molecular microbiology, 2003, Volume: 47, Issue:6

    Topics: Amidohydrolases; Anti-Bacterial Agents; Antitubercular Agents; Bacterial Proteins; Benzene Derivatives; Catalase; Cell Division; Culture Media; Cysteine; Disaccharides; Drug Resistance, Multiple, Bacterial; Glycopeptides; Inositol; Isoniazid; Microbial Sensitivity Tests; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; Oleic Acid; Oxidants; Pyrazoles; Rifampin; Sulfhydryl Compounds

2003
Solution conformations of mycothiol bimane, 1-D-GlcNAc-alpha-(1 --> 1)-D-myo-Ins and 1-D-GlcNAc-alpha-(1 --> 1)-L-myo-Ins.
    The Journal of organic chemistry, 2003, May-02, Volume: 68, Issue:9

    Topics: Actinomyces; Amidohydrolases; Cyclization; Cysteine; Disaccharides; Glycopeptides; Inositol; Molecular Conformation; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pyrazoles; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds

2003
Inactivation of mshB, a key gene in the mycothiol biosynthesis pathway in Mycobacterium smegmatis.
    Microbiology (Reading, England), 2003, Volume: 149, Issue:Pt 5

    Topics: Amidohydrolases; Amino Acid Sequence; Bacterial Proteins; Cysteine; Disaccharides; Ethionamide; Genetic Complementation Test; Glycopeptides; Inositol; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Mycobacterium smegmatis; Oxidative Stress; Pyrazoles; Recombination, Genetic; Sequence Analysis, DNA; Sulfhydryl Compounds

2003
The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA).
    Journal of bacteriology, 2003, Volume: 185, Issue:11

    Topics: Amino Acid Sequence; Bacterial Proteins; Cysteine; Disaccharides; DNA Transposable Elements; Glycopeptides; Glycosyltransferases; Inositol; Molecular Sequence Data; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; Pyrazoles; Sequence Alignment; Sulfhydryl Compounds

2003
Synthesis of 1-D- and 1-L-myo-inosityl 2-N-acetamido-2-deoxy-alpha-D-glucopyranoside establishes substrate specificity of the Mycobacterium tuberculosis enzyme AcGI deacetylase.
    Bioorganic & medicinal chemistry, 2003, Jun-12, Volume: 11, Issue:12

    Topics: Amidohydrolases; Bacterial Proteins; Cysteine; Disaccharides; Glycopeptides; Inositol; Mycobacterium tuberculosis; Pyrazoles; Recombinant Fusion Proteins; Stereoisomerism; Substrate Specificity; Sulfhydryl Compounds

2003
Synthesis of 2-deoxy-2-C-alkylglucosides of myo-inositol as possible inhibitors of a N-deacetylase enzyme in the biosynthesis of mycothiol.
    Bioorganic & medicinal chemistry letters, 2003, Jun-16, Volume: 13, Issue:12

    Topics: Amidohydrolases; Cysteine; Disaccharides; Enzyme Inhibitors; Glucosides; Glycopeptides; Inositol; Mycobacterium smegmatis; Pyrazoles; Sulfhydryl Compounds; Tritium

2003
The metabolism of nitrosothiols in the Mycobacteria: identification and characterization of S-nitrosomycothiol reductase.
    The Biochemical journal, 2003, Sep-15, Volume: 374, Issue:Pt 3

    Topics: Aldehyde Oxidoreductases; Bacterial Proteins; Carbohydrate Sequence; Cloning, Molecular; Cysteine; Disaccharides; Enzyme Stability; Glycopeptides; Hydrogen-Ion Concentration; Inositol; Mycobacterium smegmatis; Mycobacterium tuberculosis; NADH, NADPH Oxidoreductases; Pyrazoles; Recombinant Proteins; S-Nitrosoglutathione; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds

2003
Crystal structure of mycothiol synthase (Rv0819) from Mycobacterium tuberculosis shows structural homology to the GNAT family of N-acetyltransferases.
    Protein science : a publication of the Protein Society, 2003, Volume: 12, Issue:9

    Topics: Acetyltransferases; Amino Acid Motifs; Binding Sites; Crystallography, X-Ray; Cysteine; Databases as Topic; Disaccharides; Glycopeptides; Inositol; Models, Molecular; Multigene Family; Mycobacterium tuberculosis; Plasmids; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Pyrazoles; Sulfhydryl Compounds

2003
Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase.
    Biochemistry, 2003, Oct-21, Volume: 42, Issue:41

    Topics: Amidohydrolases; Amino Acid Sequence; Cloning, Molecular; Cysteine; Disaccharides; Enzyme Inhibitors; Glycopeptides; Hydrolysis; Inositol; Kinetics; Metals, Heavy; Molecular Sequence Data; Mycobacterium tuberculosis; Pyrazoles; Recombinant Proteins; Rifamycins; Substrate Specificity; Sulfhydryl Compounds

2003
Mycothiol is essential for growth of Mycobacterium tuberculosis Erdman.
    Journal of bacteriology, 2003, Volume: 185, Issue:22

    Topics: Adenosine Triphosphate; Bacterial Proteins; Culture Media; Cysteine; Disaccharides; Genes, Bacterial; Genes, Essential; Glycopeptides; Inositol; Ligases; Mycobacteriophages; Mycobacterium tuberculosis; Pyrazoles; Sulfhydryl Compounds

2003
Crystal structure of MshB from Mycobacterium tuberculosis, a deacetylase involved in mycothiol biosynthesis.
    Journal of molecular biology, 2004, Jan-23, Volume: 335, Issue:4

    Topics: Amidohydrolases; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Catalysis; Crystallography, X-Ray; Cysteine; Disaccharides; Glycopeptides; Hydrogen Bonding; Inositol; Ligands; Metals; Models, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis; Protein Structure, Secondary; Pyrazoles; Sequence Alignment; Sulfhydryl Compounds

2004
Preparation and utilization of a reagent for the isolation and purification of low-molecular-mass thiols.
    Analytical biochemistry, 2004, Feb-01, Volume: 325, Issue:1

    Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cysteine; Disaccharides; Dithiothreitol; Glutathione; Glycopeptides; Inositol; Mycobacterium smegmatis; Naphthalenes; Pyrazoles; Sulfhydryl Compounds; Sulfhydryl Reagents

2004
First total synthesis of mycothiol and mycothiol disulfide.
    Organic letters, 2004, Feb-05, Volume: 6, Issue:3

    Topics: Cysteine; Disaccharides; Glucosamine; Glycopeptides; Inositol; Molecular Structure; Pyrazoles; Sulfhydryl Compounds

2004
The Mycobacterium tuberculosis ino1 gene is essential for growth and virulence.
    Molecular microbiology, 2004, Volume: 51, Issue:4

    Topics: Amino Acid Sequence; Animals; Binding Sites; Cysteine; Disaccharides; DNA Mutational Analysis; Gene Deletion; Genes, Bacterial; Genes, Essential; Glycopeptides; Inositol; Lipopolysaccharides; Macrophages; Mice; Mice, SCID; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Mycobacterium tuberculosis; Myo-Inositol-1-Phosphate Synthase; Phosphatidylinositols; Pyrazoles; Sulfhydryl Compounds; Tuberculosis; Virulence

2004
Differential expression of mycothiol pathway genes: are they affected by antituberculosis drugs?
    IUBMB life, 2004, Volume: 56, Issue:3

    Topics: Acetylglucosamine; Animals; Antitubercular Agents; Chromosome Mapping; Computational Biology; Cysteine; Disaccharides; Enzymes; Glycopeptides; Growth Inhibitors; Humans; Inositol; Oxidoreductases; Polymorphism, Restriction Fragment Length; Pyrazoles; RNA, Antisense; Sulfhydryl Compounds

2004
Targeted mutagenesis of the Mycobacterium smegmatis mca gene, encoding a mycothiol-dependent detoxification protein.
    Journal of bacteriology, 2004, Volume: 186, Issue:18

    Topics: Amidohydrolases; Anti-Bacterial Agents; Bridged Bicyclo Compounds; Cysteine; Dinitrochlorobenzene; Disaccharides; Enzyme Inhibitors; Ethylmaleimide; Gene Deletion; Genes, Bacterial; Genetic Complementation Test; Glycopeptides; Inositol; Iodoacetamide; Mutagenesis, Insertional; Mycobacterium smegmatis; Mycobacterium tuberculosis; Naphthoquinones; Oxidants; Pyrazoles; Rifamycins; Streptomycin; Sulfhydryl Compounds; Vitamin K 3

2004
Functional demonstration of reverse transsulfuration in the Mycobacterium tuberculosis complex reveals that methionine is the preferred sulfur source for pathogenic Mycobacteria.
    The Journal of biological chemistry, 2005, Mar-04, Volume: 280, Issue:9

    Topics: Alkynes; Amino Acids; Biological Transport; Carbon-Oxygen Lyases; Cell-Free System; Chromatography, High Pressure Liquid; Cloning, Molecular; Cystathionine gamma-Lyase; Cysteine; Disaccharides; DNA Mutational Analysis; Escherichia coli; Genetic Complementation Test; Genome; Genome, Bacterial; Glycine; Glycopeptides; Homoserine; Inositol; Ions; Kinetics; Methionine; Models, Chemical; Mutation; Mycobacterium bovis; Mycobacterium tuberculosis; Plasmids; Protein Structure, Tertiary; Pyrazoles; Sulfhydryl Compounds; Sulfur; Time Factors; Ultracentrifugation; Ultraviolet Rays

2005
A mycothiol synthase mutant of Mycobacterium smegmatis produces novel thiols and has an altered thiol redox status.
    Journal of bacteriology, 2005, Volume: 187, Issue:21

    Topics: Acetyl Coenzyme A; Acetyltransferases; Acyl Coenzyme A; Benzene Derivatives; Cysteine; Disaccharides; DNA Transposable Elements; Glycopeptides; Hydrogen Peroxide; Inositol; Mutagenesis, Insertional; Mycobacterium smegmatis; Oxidants; Oxidation-Reduction; Pyrazoles; Sulfhydryl Compounds; tert-Butylhydroperoxide

2005
The substrate-induced conformational change of Mycobacterium tuberculosis mycothiol synthase.
    The Journal of biological chemistry, 2006, Feb-03, Volume: 281, Issue:5

    Topics: Acetyltransferases; Binding Sites; Coenzyme A; Crystallography, X-Ray; Cysteine; Disaccharides; Glycopeptides; Inositol; Mycobacterium tuberculosis; Protein Binding; Protein Conformation; Pyrazoles; Substrate Specificity; Sulfhydryl Compounds

2006
The gene ncgl2918 encodes a novel maleylpyruvate isomerase that needs mycothiol as cofactor and links mycothiol biosynthesis and gentisate assimilation in Corynebacterium glutamicum.
    The Journal of biological chemistry, 2006, Apr-21, Volume: 281, Issue:16

    Topics: Amino Acid Sequence; Bacterial Proteins; Carbon; Chromatography, High Pressure Liquid; cis-trans-Isomerases; Corynebacterium glutamicum; Cysteine; Disaccharides; DNA Primers; Escherichia coli; Gene Deletion; Gene Expression Regulation, Bacterial; Genes, Bacterial; Gentisates; Glycopeptides; Hydroxybenzoates; Inositol; Ions; Kinetics; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Molecular Weight; Mutation; Phenotype; Pimelic Acids; Plasmids; Pyrazoles; Spectrometry, Mass, Electrospray Ionization; Sulfhydryl Compounds; Time Factors

2006
Identification of genes for mycothiol biosynthesis in Streptomyces coelicolor A3(2).
    Journal of microbiology (Seoul, Korea), 2006, Volume: 44, Issue:1

    Topics: Acetylesterase; Acetyltransferases; Bacterial Proteins; Culture Media; Cysteine; Disaccharides; Gene Expression Regulation, Bacterial; Glycopeptides; Informatics; Inositol; Mutation; Pyrazoles; Streptomyces coelicolor; Sulfhydryl Compounds

2006
Conformational analyses of mycothiol, a critical intracellular glycothiol in Mycobacteria.
    Carbohydrate research, 2006, Jul-03, Volume: 341, Issue:9

    Topics: Carbohydrate Conformation; Cysteine; Disaccharides; Glycopeptides; Inositol; Intracellular Fluid; Mycobacterium; Pyrazoles; Sulfhydryl Compounds

2006
Purification and characterization of Mycobacterium tuberculosis 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, MshB, a mycothiol biosynthetic enzyme.
    Protein expression and purification, 2006, Volume: 47, Issue:2

    Topics: Amidohydrolases; Bacterial Proteins; Cysteine; Disaccharides; Glycopeptides; Inositol; Metalloproteins; Mycobacterium tuberculosis; Pyrazoles; Recombinant Proteins; Sulfhydryl Compounds

2006
Mycothiol-dependent mycobacterial response to oxidative stress.
    FEBS letters, 2006, May-15, Volume: 580, Issue:11

    Topics: Cysteine; Disaccharides; Glycopeptides; Inositol; Mycobacterium bovis; Mycobacterium smegmatis; Oxidation-Reduction; Oxidative Stress; Pyrazoles; Reactive Oxygen Species; Sulfhydryl Compounds; Water

2006
A coupled spectrophotometric assay for l-cysteine:1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase and its application for inhibitor screening.
    Analytical biochemistry, 2006, Jun-15, Volume: 353, Issue:2

    Topics: Antitubercular Agents; Colorimetry; Cysteine; Disaccharides; Enzyme Inhibitors; Glycopeptides; Inositol; Ligases; Molybdenum; Mycobacterium smegmatis; Mycobacterium tuberculosis; Phosphates; Phosphoric Acids; Pyrazoles; Pyrophosphatases; Rosaniline Dyes; Spectrophotometry; Sulfhydryl Compounds

2006
Foundations of antibiotic resistance in bacterial physiology: the mycobacterial paradigm.
    Trends in microbiology, 2006, Volume: 14, Issue:7

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Cell Wall; Cysteine; Disaccharides; Drug Resistance, Multiple, Bacterial; Glycopeptides; Inositol; Membrane Transport Proteins; Models, Biological; Mycobacterium; Mycobacterium tuberculosis; Permeability; Porins; Pyrazoles; Sulfhydryl Compounds; Transcription Factors

2006
Cloning, expression and rapid purification of active recombinant mycothiol ligase as B1 immunoglobulin binding domain of streptococcal protein G, glutathione-S-transferase and maltose binding protein fusion proteins in Mycobacterium smegmatis.
    Protein expression and purification, 2006, Volume: 50, Issue:1

    Topics: Bacterial Proteins; Carbohydrate Conformation; Carrier Proteins; Cloning, Molecular; Cysteine; Glutathione Transferase; Glycopeptides; Immunoglobulins; Inositol; Ligases; Maltose-Binding Proteins; Mycobacterium smegmatis; Protein Binding; Recombinant Proteins; Time Factors

2006
Biochemistry of the initial steps of mycothiol biosynthesis.
    The Journal of biological chemistry, 2006, Nov-10, Volume: 281, Issue:45

    Topics: Acetylation; Acetylglucosamine; Biochemical Phenomena; Biochemistry; Chromatography, High Pressure Liquid; Cysteine; Disaccharides; Glycopeptides; Glycosyltransferases; Inositol; Inositol Phosphates; Mass Spectrometry; Mycobacterium smegmatis; Uridine Diphosphate

2006
The mshA gene encoding the glycosyltransferase of mycothiol biosynthesis is essential in Mycobacterium tuberculosis Erdman.
    FEMS microbiology letters, 2006, Volume: 264, Issue:1

    Topics: Bacterial Proteins; Cysteine; Gene Dosage; Glycopeptides; Glycosyltransferases; Inositol; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Transduction, Genetic

2006
Design and synthesis of substrate-mimic inhibitors of mycothiol-S-conjugate amidase from Mycobacterium tuberculosis.
    Bioorganic & medicinal chemistry letters, 2007, Jan-15, Volume: 17, Issue:2

    Topics: Amidohydrolases; Chromatography, High Pressure Liquid; Cysteine; Drug Design; Enzyme Inhibitors; Glycopeptides; Glycosylation; Inositol; Mycobacterium tuberculosis; Spectrometry, Fluorescence; Structure-Activity Relationship

2007
Inositol-1-phosphate synthetase mRNA as a new target for antisense inhibition of Mycobacterium tuberculosis.
    Journal of biotechnology, 2007, Mar-10, Volume: 128, Issue:4

    Topics: Anti-Bacterial Agents; Colony Count, Microbial; Cysteine; Glycopeptides; Hydrogen Peroxide; Inositol; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Myo-Inositol-1-Phosphate Synthase; Oligonucleotides, Antisense; Oxidants; RNA, Messenger; Thionucleotides

2007
Thiols in nitric oxide synthase-containing Nocardia sp. strain NRRL 5646.
    Applied and environmental microbiology, 2007, Volume: 73, Issue:9

    Topics: Aldehyde Oxidoreductases; Base Sequence; Chromatography, High Pressure Liquid; Cysteine; Glycopeptides; Inositol; Molecular Sequence Data; Molecular Structure; Nitric Oxide; Nocardia; RNA, Ribosomal, 16S; Sequence Analysis, DNA

2007
Crystal structures and site-directed mutagenesis of a mycothiol-dependent enzyme reveal a novel folding and molecular basis for mycothiol-mediated maleylpyruvate isomerization.
    The Journal of biological chemistry, 2007, Jun-01, Volume: 282, Issue:22

    Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Catalytic Domain; cis-trans-Isomerases; Coenzymes; Corynebacterium glutamicum; Crystallography, X-Ray; Cysteine; Glycopeptides; Inositol; Isomerases; Mutation, Missense; Mycobacterium tuberculosis; Pimelic Acids; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship

2007
Synthesis of fused bicyclic thioglycosides of N-acylated glucosamine as analogues of mycothiol.
    Carbohydrate research, 2007, Sep-03, Volume: 342, Issue:12-13

    Topics: Acetylglucosamine; Bridged Bicyclo Compounds; Carbohydrate Conformation; Cysteine; Glucosamine; Glycopeptides; Inositol; Models, Molecular; Molecular Conformation; Thioglycosides

2007
Innate protection of Mycobacterium smegmatis against the antimicrobial activity of nitric oxide is provided by mycothiol.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Anti-Bacterial Agents; Cysteine; Drug Resistance, Bacterial; Genes, Bacterial; Glycopeptides; Inositol; Mutation; Mycobacterium smegmatis; Nitric Oxide

2007
Mycothiol import by Mycobacterium smegmatis and function as a resource for metabolic precursors and energy production.
    Journal of bacteriology, 2007, Volume: 189, Issue:19

    Topics: Acetylcysteine; Carbon Radioisotopes; Cysteine; Glycopeptides; Inositol; Inositol Phosphates; Models, Biological; Molecular Structure; Mutation; Mycobacterium smegmatis; Pyruvic Acid

2007
Comparative analysis of mutants in the mycothiol biosynthesis pathway in Mycobacterium smegmatis.
    Biochemical and biophysical research communications, 2007, Nov-09, Volume: 363, Issue:1

    Topics: Acetyltransferases; Cysteine; Glycopeptides; Inositol; Mutation; Mycobacterium smegmatis; NADH, NADPH Oxidoreductases; Signal Transduction

2007
Steady-state and pre-steady-state kinetic analysis of Mycobacterium smegmatis cysteine ligase (MshC).
    Biochemistry, 2007, Oct-09, Volume: 46, Issue:40

    Topics: Adenosine Triphosphate; Catalysis; Cysteine; Diphosphates; Glucosamine; Glycopeptides; Hydrogen-Ion Concentration; Inositol; Kinetics; Ligases; Models, Chemical; Molecular Structure; Mycobacterium smegmatis

2007
Synthesis of natural product-inspired inhibitors of Mycobacterium tuberculosis mycothiol-associated enzymes: the first inhibitors of GlcNAc-Ins deacetylase.
    Journal of medicinal chemistry, 2007, Dec-13, Volume: 50, Issue:25

    Topics: Amidohydrolases; Bacterial Proteins; Binding Sites; Cysteine; Furans; Glycopeptides; Inositol; Isoxazoles; Models, Molecular; Mycobacterium tuberculosis; Oxazines; Oxazoles; Protein Binding; Pyrans; Stereoisomerism; Sulfonamides; Thioglycosides

2007
Mycothiol disulfide reductase: solid phase synthesis and evaluation of alternative substrate analogues.
    Organic & biomolecular chemistry, 2008, Jan-21, Volume: 6, Issue:2

    Topics: Binding Sites; Combinatorial Chemistry Techniques; Cysteine; Disulfides; Enzyme Activation; Enzyme Inhibitors; Glycopeptides; Glycosides; Inositol; Kinetics; Molecular Conformation; NADH, NADPH Oxidoreductases; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2008
Regulation of mycothiol metabolism by sigma(R) and the thiol redox sensor anti-sigma factor RsrA.
    Molecular microbiology, 2008, Volume: 68, Issue:4

    Topics: Actinobacteria; Bacterial Proteins; Cysteine; Gene Expression Regulation, Bacterial; Glycopeptides; Inositol; Sigma Factor; Streptomyces coelicolor; Sulfhydryl Compounds; Transcription Factors

2008
Mycothiol regulates and is regulated by a thiol-specific antisigma factor RsrA and sigma(R) in Streptomyces coelicolor.
    Molecular microbiology, 2008, Volume: 68, Issue:4

    Topics: Alkylating Agents; Amidohydrolases; Anti-Bacterial Agents; Bacterial Proteins; Cysteine; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Glycopeptides; Inositol; Mutation; Regulon; Sigma Factor; Streptomyces coelicolor; Transcription Factors

2008
An N-acyl homolog of mycothiol is produced in marine actinomycetes.
    Archives of microbiology, 2008, Volume: 190, Issue:5

    Topics: Actinobacteria; Amidohydrolases; Biosynthetic Pathways; Cysteine; Glycopeptides; Inositol; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Water Microbiology

2008
Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis.
    Molecular microbiology, 2008, Volume: 69, Issue:5

    Topics: Amino Acid Sequence; Animals; Antitubercular Agents; Bacterial Proteins; Catalase; Corynebacterium glutamicum; Cysteine; Drug Resistance, Bacterial; Ethionamide; Glycopeptides; Glycosyltransferases; Humans; Inositol; Isoniazid; Mice; Mice, Inbred C57BL; Mice, SCID; Microbial Sensitivity Tests; Mixed Function Oxygenases; Molecular Sequence Data; Mycobacterium Infections; Mycobacterium tuberculosis; Sequence Alignment; Sequence Deletion; Tuberculosis, Multidrug-Resistant

2008
Unusual production of glutathione in Actinobacteria.
    Archives of microbiology, 2009, Volume: 191, Issue:1

    Topics: Actinobacteria; Amino Acid Sequence; Bacterial Proteins; Cysteine; Glutathione; Glycopeptides; Inositol; Molecular Sequence Data; Sequence Alignment

2009
The 1.6 A crystal structure of Mycobacterium smegmatis MshC: the penultimate enzyme in the mycothiol biosynthetic pathway.
    Biochemistry, 2008, Dec-16, Volume: 47, Issue:50

    Topics: Bacterial Proteins; Binding Sites; Carbon-Nitrogen Ligases; Conserved Sequence; Crystallization; Crystallography, X-Ray; Cysteine; Glycopeptides; Hydrolysis; Inositol; Mycobacterium smegmatis; Protein Binding; Protein Structure, Secondary; Substrate Specificity; Trypsin

2008
Combinations of N-Acetyl-S-(N-2-Phenethylthiocarbamoyl)-L-Cysteine and myo-inositol inhibit tobacco carcinogen-induced lung adenocarcinoma in mice.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; bcl-Associated Death Protein; Carcinogens; Cell Proliferation; Cysteine; Drug Evaluation, Preclinical; Female; Inositol; Lung Neoplasms; Mice; Models, Biological; Oncogene Protein v-akt; Phosphorylation; Poly(ADP-ribose) Polymerases; Random Allocation; Smoking; Thiocarbamates

2008
Mycothiol disulfide reductase: a continuous assay for slow time-dependent inhibitors.
    Analytical biochemistry, 2009, May-01, Volume: 388, Issue:1

    Topics: Cysteine; Enzyme Assays; Enzyme Inhibitors; Glycopeptides; Inositol; Kinetics; NADH, NADPH Oxidoreductases; NADP; Recombinant Proteins; Substrate Specificity; Sulfhydryl Compounds; Time Factors

2009
Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange.
    The Journal of biological chemistry, 2009, May-29, Volume: 284, Issue:22

    Topics: Arsenate Reductases; Arsenates; Arsenites; Biocatalysis; Corynebacterium glutamicum; Cysteine; Disulfides; Electron Transport; Electrons; Genes, Bacterial; Glycopeptides; Inositol; Kinetics; Oxidation-Reduction; Substrate Specificity; Sulfhydryl Compounds

2009
Toward the catalytic mechanism of a cysteine ligase (MshC) from Mycobacterium smegmatis: an enzyme involved in the biosynthetic pathway of mycothiol.
    Biochemistry, 2009, Aug-04, Volume: 48, Issue:30

    Topics: Adenosine; Adenosine Triphosphate; Biosynthetic Pathways; Carbon-Nitrogen Ligases; Catalytic Domain; Cysteine; Glycopeptides; Hydrogen-Ion Concentration; Imidazoles; Inositol; Ligases; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Mycobacterium smegmatis; Protein Structure, Tertiary

2009
Dequalinium, a new inhibitor of Mycobacterium tuberculosis mycothiol ligase identified by high-throughput screening.
    Journal of biomolecular screening, 2009, Volume: 14, Issue:6

    Topics: Anti-Infective Agents; Bacterial Proteins; Carrier Proteins; Cysteine; Dequalinium; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glycopeptides; Inositol; Kinetics; Ligases; Luminescent Measurements; Maltose-Binding Proteins; Mycobacterium tuberculosis

2009
Conjugates of plumbagin and phenyl-2-amino-1-thioglucoside inhibit MshB, a deacetylase involved in the biosynthesis of mycothiol.
    Bioorganic & medicinal chemistry, 2010, Apr-01, Volume: 18, Issue:7

    Topics: Acetylcysteine; Amidohydrolases; Bacterial Proteins; Cell Survival; Cysteine; Enzyme Inhibitors; Glycopeptides; Indicators and Reagents; Inositol; Mycobacterium tuberculosis; NADH, NADPH Oxidoreductases; Naphthoquinones; Oxidation-Reduction; Structure-Activity Relationship; Substrate Specificity; Thioglucosides

2010
Intramolecular alpha-glucosaminidation: synthesis of mycothiol.
    Organic letters, 2010, Jun-04, Volume: 12, Issue:11

    Topics: Catalysis; Cysteine; Glucosamine; Glycopeptides; Glycosylation; Inositol; Molecular Structure; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism; Thioglycosides

2010
Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination.
    Carcinogenesis, 2010, Volume: 31, Issue:9

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzo(a)pyrene; Bronchi; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Cysteine; Epithelial Cells; Female; Humans; Indoles; Inositol; Lung Neoplasms; Mice; Mice, Inbred A; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Proto-Oncogene Proteins c-akt; Signal Transduction; Smoke; Thiocarbamates; Vitamin B Complex

2010
Characterization of the N-acetyl-α-D-glucosaminyl l-malate synthase and deacetylase functions for bacillithiol biosynthesis in Bacillus anthracis .
    Biochemistry, 2010, Sep-28, Volume: 49, Issue:38

    Topics: Bacillus anthracis; Binding Sites; Borohydrides; Cysteine; Glucosamine; Glycopeptides; Glycosyltransferases; Inositol; Intramolecular Lyases; Molecular Weight; Oxidation-Reduction; Sulfhydryl Compounds; Uridine Diphosphate

2010
Identification and quantification of mycothiol in Actinobacteria by a novel enzymatic method.
    Applied microbiology and biotechnology, 2010, Volume: 88, Issue:6

    Topics: Actinobacteria; Chemistry Techniques, Analytical; cis-trans-Isomerases; Corynebacterium glutamicum; Cysteine; Glycopeptides; Inositol

2010
Organic hydroperoxide resistance protein and ergothioneine compensate for loss of mycothiol in Mycobacterium smegmatis mutants.
    Journal of bacteriology, 2011, Volume: 193, Issue:8

    Topics: Antitubercular Agents; Bacterial Proteins; Biosynthetic Pathways; Cysteine; DNA Transposable Elements; Drug Resistance, Bacterial; Ergothioneine; Glycopeptides; Hydrogen Peroxide; Inositol; Isoniazid; Microbial Viability; Mutagenesis, Insertional; Mycobacterium smegmatis

2011
Precise null deletion mutations of the mycothiol synthesis genes reveal their role in isoniazid and ethionamide resistance in Mycobacterium smegmatis.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7

    Topics: Antitubercular Agents; Bacterial Proteins; Cysteine; Drug Resistance, Multiple, Bacterial; Ethionamide; Glycopeptides; Inositol; Isoniazid; Mycobacterium smegmatis; Sequence Deletion

2011
The activity and cofactor preferences of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) change depending on environmental conditions.
    The Journal of biological chemistry, 2011, Jun-10, Volume: 286, Issue:23

    Topics: Amidohydrolases; Bacterial Proteins; Coenzymes; Cysteine; Glycopeptides; Inositol; Metals, Heavy; Mycobacterium smegmatis; Mycobacterium tuberculosis

2011
Evaluation of NTF1836 as an inhibitor of the mycothiol biosynthetic enzyme MshC in growing and non-replicating Mycobacterium tuberculosis.
    Bioorganic & medicinal chemistry, 2011, Jul-01, Volume: 19, Issue:13

    Topics: Animals; Bacterial Proteins; Chlorocebus aethiops; Cysteine; Dibenzothiazepines; Drug Evaluation, Preclinical; Enzyme Inhibitors; Glycopeptides; Inositol; Mycobacterium tuberculosis; Structure-Activity Relationship; Vero Cells

2011
Coresistance to isoniazid and ethionamide maps to mycothiol biosynthetic genes in Mycobacterium bovis.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:9

    Topics: Antitubercular Agents; Bacterial Proteins; Carbon-Sulfur Lyases; Cysteine; Drug Resistance, Bacterial; Ethionamide; Glycopeptides; Glycosyltransferases; Inositol; Isoniazid; Mycobacterium bovis

2011
Palmitoylation targets AKAP79 protein to lipid rafts and promotes its regulation of calcium-sensitive adenylyl cyclase type 8.
    The Journal of biological chemistry, 2011, Sep-23, Volume: 286, Issue:38

    Topics: A Kinase Anchor Proteins; Adenylyl Cyclases; Animals; Calcium; Cell Line; Centrifugation, Density Gradient; Cyclic AMP-Dependent Protein Kinases; Cysteine; Diffusion; Fluorescence Recovery After Photobleaching; Humans; Inositol; Lipoylation; Membrane Microdomains; Octoxynol; Palmitates; Phosphorylation; Protein Binding; Rats; Receptors, Adrenergic, beta; Solubility; Subcellular Fractions; Substrate Specificity

2011
Desymmetrization of 2,4,5,6-tetra-O-benzyl-D-myo-inositol for the synthesis of mycothiol.
    Organic letters, 2011, Oct-21, Volume: 13, Issue:20

    Topics: Animals; Benzyl Compounds; Cysteine; Glycopeptides; Inositol; Inositol Phosphates; Molecular Structure; Stereoisomerism

2011
The DinB superfamily includes novel mycothiol, bacillithiol, and glutathione S-transferases.
    Biochemistry, 2011, Dec-13, Volume: 50, Issue:49

    Topics: Amidohydrolases; Bacterial Proteins; Cloning, Molecular; Cysteine; Enterococcus faecalis; Glucosamine; Glutathione Transferase; Glycopeptides; Inositol; Multigene Family; Mycobacterium smegmatis; Mycobacterium tuberculosis; Phylogeny; Pyrazoles; Sequence Homology, Amino Acid

2011
Thiols screened by the neocarzinostatin protein for preserving or detoxifying its bound enediyne antibiotic.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2012, May-14, Volume: 18, Issue:20

    Topics: Anti-Bacterial Agents; Cysteine; Enediynes; Glutathione; Glycopeptides; Inositol; Molecular Structure; Streptomyces; Sulfhydryl Compounds; Zinostatin

2012
Characterization of BshA, bacillithiol glycosyltransferase from Staphylococcus aureus and Bacillus subtilis.
    FEBS letters, 2012, Apr-05, Volume: 586, Issue:7

    Topics: Antioxidants; Bacillaceae Infections; Bacillus subtilis; Bacterial Proteins; Cysteine; Enzyme Inhibitors; Glucosamine; Glycopeptides; Inositol; Kinetics; Malates; Models, Molecular; Molecular Targeted Therapy; Molecular Weight; N-Acetylglucosaminyltransferases; Protein Conformation; Recombinant Proteins; Staphylococcal Infections; Staphylococcus aureus; Substrate Specificity; Uridine Diphosphate N-Acetylglucosamine

2012
An enzyme-initiated Smiles rearrangement enables the development of an assay of MshB, the GlcNAc-Ins deacetylase of mycothiol biosynthesis.
    Organic & biomolecular chemistry, 2012, Jul-21, Volume: 10, Issue:27

    Topics: Amidohydrolases; Bacterial Proteins; Biocatalysis; Catalytic Domain; Cysteine; Glycopeptides; Inositol; Models, Molecular; Mycobacterium tuberculosis; Substrate Specificity

2012
Mycoredoxin-1 is one of the missing links in the oxidative stress defence mechanism of Mycobacteria.
    Molecular microbiology, 2012, Volume: 86, Issue:4

    Topics: Cysteine; Disulfides; Gene Deletion; Glycopeptides; Inositol; Magnetic Resonance Spectroscopy; Models, Molecular; Mycobacterium smegmatis; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Protein Conformation

2012
Nickel-catalyzed α-glycosylation of C(1)-hydroxyl D-myo-inositol: a formal synthesis of mycothiol.
    Chemical communications (Cambridge, England), 2013, May-14, Volume: 49, Issue:39

    Topics: Catalysis; Cysteine; Glycopeptides; Glycosylation; Inositol; Nickel; Streptomyces

2013
Bacterial mechanisms of reversible protein S-thiolation: structural and mechanistic insights into mycoredoxins.
    Molecular microbiology, 2012, Volume: 86, Issue:4

    Topics: Cysteine; Glycopeptides; Inositol; Mycobacterium smegmatis; Oxidative Stress; Oxidoreductases

2012
NrdH-redoxin of Mycobacterium tuberculosis and Corynebacterium glutamicum dimerizes at high protein concentration and exclusively receives electrons from thioredoxin reductase.
    The Journal of biological chemistry, 2013, Mar-15, Volume: 288, Issue:11

    Topics: Amino Acid Sequence; Antitubercular Agents; Catalytic Domain; Cloning, Molecular; Corynebacterium glutamicum; Crystallography, X-Ray; Cysteine; Dimerization; Electrons; Escherichia coli Proteins; Glycopeptides; Hydrogen-Ion Concentration; Inositol; Kinetics; Molecular Conformation; Molecular Sequence Data; Mycobacterium tuberculosis; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Ribonucleotides; Scattering, Radiation; Sequence Homology, Amino Acid; Surface Properties; Thioredoxin-Disulfide Reductase; Thioredoxins; X-Rays

2013
Conformational preferences of plumbagin with phenyl-1-thioglucoside conjugates in solution and bound to MshB determined by aromatic association.
    Carbohydrate research, 2013, Apr-19, Volume: 371

    Topics: Amidohydrolases; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cysteine; Enzyme Inhibitors; Glycopeptides; Inositol; Kinetics; Ligands; Molecular Conformation; Molecular Docking Simulation; Mycobacterium tuberculosis; Naphthoquinones; Protein Structure, Secondary; Superoxides; Thermodynamics; Thioglucosides

2013
Physiological roles of mycothiol in detoxification and tolerance to multiple poisonous chemicals in Corynebacterium glutamicum.
    Archives of microbiology, 2013, Volume: 195, Issue:6

    Topics: Corynebacterium glutamicum; Cysteine; Ethanol; Glycopeptides; Inactivation, Metabolic; Industrial Microbiology; Inositol; Metals, Heavy; Naphthalenes; Oxidation-Reduction; Resorcinols

2013
Ergothioneine is a secreted antioxidant in Mycobacterium smegmatis.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7

    Topics: Antioxidants; Bacterial Proteins; Culture Media; Cysteine; Drug Resistance, Bacterial; Ergothioneine; Glycopeptides; Inositol; Microbial Sensitivity Tests; Mutation; Mycobacterium smegmatis; Oxidative Stress

2013
Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction.
    Nature communications, 2013, Volume: 4

    Topics: Antitubercular Agents; Ascorbic Acid; Cysteine; DNA Damage; Drug Resistance, Bacterial; Glycopeptides; Hydrogen Peroxide; Inositol; Iron; Lipids; Microbial Sensitivity Tests; Microbial Viability; Models, Biological; Mycobacterium tuberculosis; Oxidants; Reactive Oxygen Species; Sterilization; Transcription, Genetic

2013
Protein S-mycothiolation functions as redox-switch and thiol protection mechanism in Corynebacterium glutamicum under hypochlorite stress.
    Antioxidants & redox signaling, 2014, Feb-01, Volume: 20, Issue:4

    Topics: Bacterial Proteins; Corynebacterium glutamicum; Cysteine; Disulfides; Glucose; Glycogen; Glycopeptides; Inositol; Oxidants; Oxidation-Reduction; Peroxidases; Protein Processing, Post-Translational; Proteome; Sodium Hypochlorite; Stress, Physiological; Transcriptome

2014
Automated docking studies provide insights into molecular determinants of ligand recognition by N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside deacetylase (MshB).
    Biopolymers, 2014, Volume: 101, Issue:4

    Topics: Amidohydrolases; Bacterial Proteins; Crystallography, X-Ray; Cysteine; Glycopeptides; Hydrogen Bonding; Inositol; Ligands; Molecular Docking Simulation; Mycobacterium tuberculosis; Protein Structure, Secondary; Substrate Specificity; Thermodynamics

2014
Mycothiol/mycoredoxin 1-dependent reduction of the peroxiredoxin AhpE from Mycobacterium tuberculosis.
    The Journal of biological chemistry, 2014, Feb-21, Volume: 289, Issue:8

    Topics: Bacterial Proteins; Biocatalysis; Cysteine; Disulfides; Glycopeptides; Hydrogen Peroxide; Hydrogen-Ion Concentration; Inositol; Kinetics; Models, Biological; Mycobacterium tuberculosis; NADP; Oxidation-Reduction; Peroxiredoxins

2014
Reengineering redox sensitive GFP to measure mycothiol redox potential of Mycobacterium tuberculosis during infection.
    PLoS pathogens, 2014, Volume: 10, Issue:1

    Topics: Cell Line, Tumor; Cysteine; Glycopeptides; Green Fluorescent Proteins; Humans; Inositol; Macrophages; Mycobacterium tuberculosis; Oxidation-Reduction; Protein Engineering; Tuberculosis

2014
Protein disulfide isomerase A6 controls the decay of IRE1α signaling via disulfide-dependent association.
    Molecular cell, 2014, Feb-20, Volume: 53, Issue:4

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Proliferation; Cysteine; Disulfides; Endoplasmic Reticulum; Gene Expression Regulation, Enzymologic; HEK293 Cells; Humans; Inositol; Mice; Molecular Sequence Data; Oxygen; Phosphorylation; Protein Denaturation; Protein Disulfide-Isomerases; Protein Folding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; RNA, Messenger; Sequence Homology, Amino Acid; Signal Transduction

2014
Enhancing Corynebacterium glutamicum robustness by over-expressing a gene, mshA, for mycothiol glycosyltransferase.
    Biotechnology letters, 2014, Volume: 36, Issue:7

    Topics: Corynebacterium glutamicum; Cysteine; Gene Expression; Glycopeptides; Glycosyltransferases; Inositol; Microbial Viability; Stress, Physiological

2014
Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A.
    Nature, 2015, Feb-05, Volume: 518, Issue:7537

    Topics: Anti-Bacterial Agents; Biological Products; Biosynthetic Pathways; Biotransformation; Cysteine; Ergothioneine; Glycopeptides; Glycosylation; Inositol; Lincomycin; Lincosamides; Molecular Sequence Data; Streptomyces

2015
Biochemistry: Elusive source of sulfur unravelled.
    Nature, 2015, Feb-05, Volume: 518, Issue:7537

    Topics: Anti-Bacterial Agents; Cysteine; Ergothioneine; Glycopeptides; Inositol; Lincomycin; Streptomyces

2015
Ergothioneine protects Streptomyces coelicolor A3(2) from oxidative stresses.
    Journal of bioscience and bioengineering, 2015, Volume: 120, Issue:3

    Topics: Cysteine; Ergothioneine; Glutamate-Cysteine Ligase; Glycopeptides; Hydrogen Peroxide; Inositol; Oxidative Stress; Streptomyces coelicolor

2015
The active site of yeast phosphatidylinositol synthase Pis1 is facing the cytosol.
    Biochimica et biophysica acta, 2015, Volume: 1851, Issue:5

    Topics: Algorithms; Catalytic Domain; CDP-Diacylglycerol-Inositol 3-Phosphatidyltransferase; Computational Biology; Cysteine; Cytidine Diphosphate Diglycerides; Cytosol; Detergents; Enzyme Activation; Enzyme Stability; Inositol; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Denaturation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Structure-Activity Relationship; Substrate Specificity; Time Factors; Transferases (Other Substituted Phosphate Groups)

2015
Lincosamide synthetase--a unique condensation system combining elements of nonribosomal peptide synthetase and mycothiol metabolism.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Cysteine; Glycopeptides; Inositol; Lincomycin; Lincosamides; Peptide Synthases

2015
Corynebacterium diphtheriae methionine sulfoxide reductase a exploits a unique mycothiol redox relay mechanism.
    The Journal of biological chemistry, 2015, May-01, Volume: 290, Issue:18

    Topics: Amino Acid Sequence; Catalytic Domain; Corynebacterium diphtheriae; Cysteine; Disulfides; Glycopeptides; Inositol; Methionine; Methionine Sulfoxide Reductases; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Oxidoreductases; Thioredoxin-Disulfide Reductase; Thioredoxins

2015
The Corynebacterium glutamicum mycothiol peroxidase is a reactive oxygen species-scavenging enzyme that shows promiscuity in thiol redox control.
    Molecular microbiology, 2015, Volume: 96, Issue:6

    Topics: Bacterial Proteins; Corynebacterium glutamicum; Cysteine; Disulfides; Glycopeptides; Hydrogen Peroxide; Inositol; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Peroxidases; Reactive Oxygen Species; Sequence Analysis, Protein; Sulfhydryl Compounds; Thioredoxins

2015
Synthesis of mycothiol conjugate analogues and evaluation of their antimycobacterial activity.
    Bioorganic & medicinal chemistry letters, 2015, Volume: 25, Issue:10

    Topics: Antitubercular Agents; Cysteine; Glycopeptides; Inositol; Microbial Sensitivity Tests; Mycobacterium tuberculosis

2015
Biosynthesis of mercapturic acid derivative of the labdane-type diterpene, cyslabdan that potentiates imipenem activity against methicillin-resistant Staphylococcus aureus: cyslabdan is generated by mycothiol-mediated xenobiotic detoxification.
    Journal of industrial microbiology & biotechnology, 2016, Volume: 43, Issue:2-3

    Topics: Acetylcysteine; Amidohydrolases; Biosynthetic Pathways; Cysteine; Diterpenes; Glycopeptides; Imipenem; Inactivation, Metabolic; Inositol; Methicillin-Resistant Staphylococcus aureus; Multigene Family; Mycelium; Organophosphates; Streptomyces; Xenobiotics

2016
The versatile low-molecular-weight thiols: Beyond cell protection.
    BioEssays : news and reviews in molecular, cellular and developmental biology, 2015, Volume: 37, Issue:12

    Topics: Biological Products; Carbohydrates; Cysteine; Ergothioneine; Glycopeptides; Glycosylation; Inositol; Molecular Weight; Oxidation-Reduction; Sulfhydryl Compounds

2015
Mycobacterium tuberculosis WhiB3 Responds to Vacuolar pH-induced Changes in Mycothiol Redox Potential to Modulate Phagosomal Maturation and Virulence.
    The Journal of biological chemistry, 2016, Feb-05, Volume: 291, Issue:6

    Topics: Animals; Bacterial Proteins; Cell Line, Tumor; Cysteine; Glycopeptides; Humans; Hydrogen-Ion Concentration; Immunity, Innate; Inositol; Mice; Mycobacterium tuberculosis; Oxidation-Reduction; Phagosomes; Vacuoles

2016
Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis.
    Cell reports, 2016, Jan-26, Volume: 14, Issue:3

    Topics: Animals; Antioxidants; Antitubercular Agents; Bacterial Proteins; Carbon; Cell Line; Chromatography, High Pressure Liquid; Cysteine; Disease Susceptibility; Energy Metabolism; Ergothioneine; Glycopeptides; Inositol; Lung; Macrophages; Mice; Mycobacterium tuberculosis; Oxidation-Reduction; Principal Component Analysis; Tandem Mass Spectrometry; Transcription Factors; Virulence

2016
Persistent Mycobacterium bovis-BCG is resistant to glutathione induced reductive stress killing.
    Microbial pathogenesis, 2016, Volume: 95

    Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Cysteine; Cytosol; Glutathione; Glycopeptides; Inositol; Microbial Viability; Mycobacterium bovis; NAD; Oxidation-Reduction

2016
Mycothiol peroxidase MPx protects Corynebacterium glutamicum against acid stress by scavenging ROS.
    Biotechnology letters, 2016, Volume: 38, Issue:7

    Topics: Acids; Corynebacterium glutamicum; Cysteine; Glycopeptides; Inositol; Peroxidases; Protein Carbonylation; Reactive Oxygen Species; Sigma Factor

2016
Mycothiol protects Corynebacterium glutamicum against acid stress via maintaining intracellular pH homeostasis, scavenging ROS, and S-mycothiolating MetE.
    The Journal of general and applied microbiology, 2016, Jul-14, Volume: 62, Issue:3

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bacterial Proteins; Corynebacterium glutamicum; Cysteine; Glycopeptides; Homeostasis; Hydrogen-Ion Concentration; Inositol; Methionine; Oxidoreductases; Reactive Oxygen Species; Recombinant Proteins; Stress, Physiological

2016
S-nitrosomycothiol reductase and mycothiol are required for survival under aldehyde stress and biofilm formation in Mycobacterium smegmatis.
    IUBMB life, 2016, Volume: 68, Issue:8

    Topics: Aldehyde Oxidoreductases; Aldehydes; Biofilms; Cysteine; Cysteine Synthase; Glycopeptides; Inositol; Mycobacterium Infections, Nontuberculous; Mycobacterium smegmatis; S-Nitrosothiols

2016
Thiol Redox and pKa Properties of Mycothiol, the Predominant Low-Molecular-Weight Thiol Cofactor in the Actinomycetes.
    Chembiochem : a European journal of chemical biology, 2016, 09-15, Volume: 17, Issue:18

    Topics: Actinobacteria; Coenzymes; Cysteine; Glycopeptides; Hydrogen-Ion Concentration; Inositol; Molecular Conformation; Molecular Weight; Oxidation-Reduction; Sulfhydryl Compounds

2016
Overexpression of Mycothiol Disulfide Reductase Enhances Corynebacterium glutamicum Robustness by Modulating Cellular Redox Homeostasis and Antioxidant Proteins under Oxidative Stress.
    Scientific reports, 2016, 07-07, Volume: 6

    Topics: Bacterial Proteins; Corynebacterium glutamicum; Cysteine; Glycopeptides; Homeostasis; Inositol; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxidative Stress

2016
Redox chemistry of Mycobacterium tuberculosis alkylhydroperoxide reductase E (AhpE): Structural and mechanistic insight into a mycoredoxin-1 independent reductive pathway of AhpE via mycothiol.
    Free radical biology & medicine, 2016, Volume: 97

    Topics: Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Cysteine; Glycopeptides; Hydrogen Bonding; Inositol; Metabolic Networks and Pathways; Molecular Docking Simulation; Mycobacterium tuberculosis; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peroxiredoxins; Protein Binding; Protein Conformation, alpha-Helical; Protein Structure, Quaternary; Scattering, Small Angle; Solutions; Thioredoxins

2016
Theoretical Insights into the Reaction and Inhibition Mechanism of Metal-Independent Retaining Glycosyltransferase Responsible for Mycothiol Biosynthesis.
    The journal of physical chemistry. B, 2017, 01-26, Volume: 121, Issue:3

    Topics: Amidohydrolases; Bacterial Proteins; Biocatalysis; Cysteine; Glycopeptides; Glycosyltransferases; Inositol; Metals; Mycobacterium tuberculosis; Quantum Theory

2017
Proteome analysis reveals differential expression of proteins involved in triacylglycerol accumulation by Rhodococcus jostii RHA1 after addition of methyl viologen.
    Microbiology (Reading, England), 2017, Volume: 163, Issue:3

    Topics: Acyl Coenzyme A; Adaptation, Physiological; Catalase; Cysteine; Fatty Acids; Glycopeptides; Inositol; NADP; Nitrogen; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Paraquat; Peroxiredoxins; Proteome; Rhodococcus; Superoxide Dismutase; Triglycerides

2017
Biochemical studies of inositol N-acetylglucosaminyltransferase involved in mycothiol biosynthesis in Corynebacterium diphtheria.
    Organic & biomolecular chemistry, 2017, May-03, Volume: 15, Issue:17

    Topics: Catalytic Domain; Corynebacterium diphtheriae; Cysteine; Glycopeptides; Inositol; Kinetics; Models, Molecular; Mutagenesis; N-Acetylglucosaminyltransferases; Structure-Activity Relationship; Substrate Specificity

2017
Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress.
    Scientific reports, 2017, 04-26, Volume: 7, Issue:1

    Topics: Bacterial Proteins; Cysteine; Gene Expression Profiling; Glycopeptides; Hypochlorous Acid; Inositol; Metabolic Networks and Pathways; Metabolome; Mycobacterium smegmatis; Oxidants; Oxidation-Reduction; Protein Processing, Post-Translational; Proteome; Stress, Physiological

2017
The glyceraldehyde-3-phosphate dehydrogenase GapDH of Corynebacterium diphtheriae is redox-controlled by protein S-mycothiolation under oxidative stress.
    Scientific reports, 2017, 07-10, Volume: 7, Issue:1

    Topics: Bacterial Proteins; Catalytic Domain; Corynebacterium diphtheriae; Cysteine; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycopeptides; Hydrogen Peroxide; Inositol; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Proteomics; Sodium Hypochlorite

2017
Mycothiol acetyltransferase (Rv0819) of Mycobacterium tuberculosis is a potential biomarker for direct diagnosis of tuberculosis using patient serum specimens.
    Letters in applied microbiology, 2017, Volume: 65, Issue:6

    Topics: Acetyltransferases; Adult; Aged; Antigens, Bacterial; Biomarkers; Cloning, Molecular; Cysteine; Early Diagnosis; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Female; Glycopeptides; Humans; Inositol; Male; Middle Aged; Mycobacterium tuberculosis; Sensitivity and Specificity; Tuberculosis, Pulmonary; Young Adult

2017
Gamma-glutamylcysteine protects ergothioneine-deficient Mycobacterium tuberculosis mutants against oxidative and nitrosative stress.
    Biochemical and biophysical research communications, 2018, 01-01, Volume: 495, Issue:1

    Topics: Biosynthetic Pathways; Cysteine; Dipeptides; Ergothioneine; Gene Deletion; Glycopeptides; Humans; Inositol; Mycobacterium tuberculosis; Nitrosative Stress; Oxidative Stress; Tuberculosis

2018
Synthesis of substrate analogues as potential inhibitors for Mycobacterium tuberculosis enzyme MshC.
    Carbohydrate research, 2017, Dec-01, Volume: 453-454

    Topics: Bacterial Proteins; Cysteine; Enzyme Inhibitors; Glycopeptides; Glycosylation; Inositol; Mycobacterium tuberculosis; Stereoisomerism

2017
Alternative Thiol-Based Redox Systems.
    Antioxidants & redox signaling, 2018, 02-20, Volume: 28, Issue:6

    Topics: Bacteria; Cysteine; Ergothioneine; Glucosamine; Glutathione; Glycopeptides; Homeostasis; Inositol; Oxidation-Reduction; Oxidative Stress; Sulfhydryl Compounds; Thioredoxins

2018
Substrate-induced structural alterations of Mycobacterial mycothione reductase and critical residues involved.
    FEBS letters, 2018, Volume: 592, Issue:4

    Topics: Cysteine; Glycopeptides; Inositol; Models, Molecular; Mutation; Mycobacterium tuberculosis; NADP; Oxidation-Reduction; Oxidoreductases; Protein Binding; Protein Multimerization; Protein Structure, Quaternary

2018
Identification of a Mycothiol-Dependent Nitroreductase from Mycobacterium tuberculosis.
    ACS infectious diseases, 2018, 05-11, Volume: 4, Issue:5

    Topics: Animals; Bacterial Proteins; Binding Sites; Cysteine; Disease Models, Animal; Enzyme Activation; Female; Glycopeptides; Inositol; Mice; Models, Molecular; Mutation; Mycobacterium tuberculosis; Nitroreductases; Oxidation-Reduction; Oxidative Stress; Phylogeny; Protein Binding; Protein Conformation; Structure-Activity Relationship; Tuberculosis

2018
The functional interplay of low molecular weight thiols in Mycobacterium tuberculosis.
    Journal of biomedical science, 2018, Jul-12, Volume: 25, Issue:1

    Topics: Animals; Cysteine; Dipeptides; Ergothioneine; Glycopeptides; Humans; Inositol; Mice; Molecular Weight; Mycobacterium tuberculosis; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species; Sulfhydryl Compounds; Tuberculosis

2018
Generation and characterization of thiol-deficient Mycobacterium tuberculosis mutants.
    Scientific data, 2018, 09-25, Volume: 5

    Topics: Bacterial Proteins; Cysteine; Dipeptides; Ergothioneine; Glycopeptides; Inositol; Mutation; Mycobacterium tuberculosis; Oxidative Stress; Sulfhydryl Compounds

2018
Myo-inositol-1-phosphate synthase (Ino-1) functions as a protection mechanism in Corynebacterium glutamicum under oxidative stress.
    MicrobiologyOpen, 2019, Volume: 8, Issue:5

    Topics: Aerobiosis; Corynebacterium glutamicum; Cysteine; Gene Deletion; Glycopeptides; Inositol; Microbial Viability; Myo-Inositol-1-Phosphate Synthase; Oxidative Stress; Protein Carbonylation; Reactive Oxygen Species

2019
Characterization and engineering control of the effects of reactive oxygen species on the conversion of sterols to steroid synthons in Mycobacterium neoaurum.
    Metabolic engineering, 2019, Volume: 56

    Topics: Cysteine; Ergothioneine; Glycopeptides; Inositol; Metabolic Engineering; Mycobacteriaceae; Reactive Oxygen Species; Sterols

2019
Characterization of Xi-class mycothiol S-transferase from Corynebacterium glutamicum and its protective effects in oxidative stress.
    Microbial cell factories, 2019, Oct-26, Volume: 18, Issue:1

    Topics: Bacterial Proteins; Corynebacterium glutamicum; Cysteine; Glutathione Transferase; Glycopeptides; Inositol; Oxidation-Reduction; Oxidative Stress

2019
Methionine sulfoxide reductase B from
    The Journal of biological chemistry, 2020, 03-13, Volume: 295, Issue:11

    Topics: Biocatalysis; Catalytic Domain; Conserved Sequence; Corynebacterium diphtheriae; Cysteine; Disulfides; Glycopeptides; Inositol; Magnetic Resonance Spectroscopy; Methionine Sulfoxide Reductases; Models, Molecular; Oxidation-Reduction; Safrole; Substrate Specificity; Sulfenic Acids; Thioredoxin-Disulfide Reductase; Thioredoxins; Zinc

2020
Glutathione: A powerful but rare cofactor among Actinobacteria.
    Advances in applied microbiology, 2020, Volume: 110

    Topics: Actinobacteria; Bacterial Proteins; Butadienes; Cysteine; Epoxy Compounds; Glutathione; Glutathione Reductase; Glutathione Transferase; Glycopeptides; Hemiterpenes; Inositol; Metabolic Networks and Pathways; Oxidation-Reduction

2020
Molecular mechanisms of Mycoredoxin-1 in resistance to oxidative stress in Corynebacterium glutamicum.
    The Journal of general and applied microbiology, 2021, Apr-16, Volume: 67, Issue:1

    Topics: Amino Acid Sequence; Bacterial Proteins; Corynebacterium glutamicum; Cysteine; Disulfides; Fungal Proteins; Genes, Fungal; Glycopeptides; Inositol; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxidative Stress; Oxidoreductases; Sigma Factor; Thioredoxins

2021
    Journal of immunology (Baltimore, Md. : 1950), 2021, 04-15, Volume: 206, Issue:8

    Topics: Anti-Bacterial Agents; Cells, Cultured; Cysteine; Glycopeptides; Humans; Hypochlorous Acid; Immune Evasion; Immunity, Innate; Inositol; Mycobacterium Infections, Nontuberculous; Mycobacterium smegmatis; Neutrophils; Phagocytosis; Phagosomes

2021
Biodesulfurization Induces Reprogramming of Sulfur Metabolism in Rhodococcus qingshengii IGTS8: Proteomics and Untargeted Metabolomics.
    Microbiology spectrum, 2021, 10-31, Volume: 9, Issue:2

    Topics: Biochemical Phenomena; Cysteine; Glycopeptides; Inositol; Metabolomics; Multigene Family; Proteomics; Rhodococcus; Sulfur; Thiophenes

2021
Involvement of a mycothiol-dependent reductase NCgl0018 in oxidative stress response of Corynebacterium glutamicum.
    The Journal of general and applied microbiology, 2021, Dec-31, Volume: 67, Issue:6

    Topics: Bacterial Proteins; Corynebacterium glutamicum; Cysteine; Disulfides; Glycopeptides; Humans; Inositol; Oxidation-Reduction; Oxidative Stress; Oxidoreductases

2021
Mycothiol Peroxidase Activity as a Part of the Self-Resistance Mechanisms against the Antitumor Antibiotic Cosmomycin D.
    Microbiology spectrum, 2022, 06-29, Volume: 10, Issue:3

    Topics: Anthracyclines; Anti-Bacterial Agents; Antioxidants; ATP-Binding Cassette Transporters; Cysteine; Glycopeptides; Inositol; Oxidoreductases; Peroxidase; Peroxidases; Streptomyces

2022
Discovery of toxoflavin, a potent IRE1α inhibitor acting through structure-dependent oxidative inhibition.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:1

    Topics: Cysteine; Endoplasmic Reticulum Stress; Endoribonucleases; Enzyme Inhibitors; Inositol; Kinetics; Molecular Docking Simulation; Oxidative Stress; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Ribonucleases

2023
Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides.
    International journal of molecular sciences, 2022, Dec-01, Volume: 23, Issue:23

    Topics: Bacterial Proteins; Cysteine; Glycopeptides; Inositol; Ligases; Mycobacterium smegmatis; Mycobacterium tuberculosis; Sulfonamides

2022