inositol 2,4,5-trisphosphate has been researched along with inositol 1,4,5-trisphosphate in 20 studies
| Studies (inositol 2,4,5-trisphosphate) | Trials (inositol 2,4,5-trisphosphate) | Recent Studies (post-2010) (inositol 2,4,5-trisphosphate) | Studies (inositol 1,4,5-trisphosphate) | Trials (inositol 1,4,5-trisphosphate) | Recent Studies (post-2010) (inositol 1,4,5-trisphosphate) |
|---|---|---|---|---|---|
| 40 | 0 | 3 | 6,600 | 1 | 589 |
| Protein | Taxonomy | inositol 2,4,5-trisphosphate (IC50) | inositol 1,4,5-trisphosphate (IC50) |
|---|---|---|---|
| Inositol-trisphosphate 3-kinase A | Rattus norvegicus (Norway rat) | 4.45 | |
| Inositol 1,4,5-trisphosphate receptor type 2 | Homo sapiens (human) | 0.03 | |
| Inositol 1,4,5-trisphosphate receptor type 3 | Homo sapiens (human) | 0.03 | |
| Inositol 1,4,5-trisphosphate receptor type 1 | Homo sapiens (human) | 0.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (75.00) | 18.2507 |
| 2000's | 4 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bird, GJ; Obie, JF; Putney, JW | 1 |
| Armstrong, DL; Bird, GS; Hughes, AR; Putney, JW; Rossier, MF; Shears, SB | 1 |
| Ferguson, JE; Han, JK; Kao, JP; Nuccitelli, R | 1 |
| Boynton, AL; Hill, TD | 1 |
| Bootman, MD; Casteels, R; De Smedt, H; Lemaire, FX; Missiaen, L; Parys, JB; Sienaert, I | 1 |
| Berridge, MJ; Petersen, CC | 1 |
| Biswas, BB; Biswas, S; Dalal, B; Raha, S | 1 |
| Desai, T; Gigg, J; Gigg, R; MartÃn-Zamora, E | 1 |
| Bird, GS; Burgess, GM; Putney, JW | 1 |
| Gallacher, DV; Rowles, SJ | 1 |
| Chang, YT; Chung, SK; Irvine, RF; Marchant, JS; Taylor, CW | 1 |
| Essen, LO; Katan, M; Perisic, O; Roberts, MF; Williams, RL; Wu, Y | 1 |
| Marchant, JS; Parker, I | 1 |
| Huang, Y; Putney, JW; Takahashi, M; Tanzawa, K | 1 |
| Furuichi, T; Iwasaki, H; Mikoshiba, K; Tanaka, T; Tomomori-Satoh, C; Uchiyama, T; Yoshikawa, F | 1 |
| Harmer, AR; Irvine, RF; Letcher, AJ; Smith, PM | 1 |
| Morris, SA; Swatton, JE; Taylor, CW; Wissing, F | 1 |
| Parekh, AB; Potter, BV; Riley, AM | 1 |
| Apiyo, D; Selby, TL; Tsai, MD; Zhao, L | 1 |
| Dupont, G; Potter, BVL; Rahman, T; Riley, AM; Rossi, AM; Taylor, CW | 1 |
20 other study(ies) available for inositol 2,4,5-trisphosphate and inositol 1,4,5-trisphosphate
| Article | Year |
|---|---|
Functional homogeneity of the non-mitochondrial Ca2+ pool in intact mouse lacrimal acinar cells.
Topics: Animals; Calcium; Cations, Divalent; Cells, Cultured; Fluorescence; Fura-2; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Lacrimal Apparatus; Male; Methacholine Chloride; Mice; Mitochondria; Ruthenium Red; Saponins; Terpenes; Thapsigargin | 1992 |
Activation of Ca2+ entry into acinar cells by a non-phosphorylatable inositol trisphosphate.
Topics: Animals; Calcium; Calcium Channels; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Lacrimal Apparatus; Methacholine Chloride; Mice; Phosphorylation; Potassium Channels; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Terpenes; Thapsigargin | 1991 |
The effects of inositol trisphosphates and inositol tetrakisphosphate on Ca2+ release and Cl- current pattern in the Xenopus laevis oocyte.
Topics: Animals; Calcium; Chloride Channels; Chlorides; Electric Conductivity; Fura-2; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Membrane Proteins; Microelectrodes; Oocytes; Xenopus laevis | 1991 |
Inositol tetrakisphosphate-induced sequestration of Ca2+ replenishes an intracellular pool sensitive to inositol trisphosphate.
Topics: Animals; Calcium; Epithelium; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Liver Neoplasms; Rats; Tumor Cells, Cultured | 1990 |
Slow kinetics of InsP3-induced Ca2+ release: differences between uni- and bi-directional 45Ca2+ fluxes.
Topics: Animals; Aorta; Biological Transport; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cell Membrane Permeability; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Guanosine Diphosphate; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Kinetics; Muscle, Smooth, Vascular; Rats; Receptors, Cytoplasmic and Nuclear; Thionucleotides | 1995 |
G-protein regulation of capacitative calcium entry may be mediated by protein kinases A and C in Xenopus oocytes.
Topics: Adenylyl Cyclases; Aluminum Compounds; Animals; Calcium; Chloride Channels; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dibutyryl Cyclic GMP; Enzyme Activation; Female; Fluorides; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Oocytes; Protein Kinase C; Tetradecanoylphorbol Acetate; Type C Phospholipases; Xenopus laevis | 1995 |
Myo-inositol trisphosphate-mediated calcium release from internal stores of Entamoeba histolytica.
Topics: Animals; Calcium; Cyclic AMP; Diltiazem; Entamoeba histolytica; Guanosine Triphosphate; Heparin; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Membranes; Second Messenger Systems; Vanadates | 1994 |
The preparation of intermediates for the synthesis of 1D-myo-inositol 1,4,5- and 2,4,5-trisphosphates, 1,4-bisphosphate 5-phosphorothioate, and 4,5-bisphosphate 1-phosphorothioate from 1D-3,6-di-O-benzyl-1,2-O-isopropylidene-myo-inositol.
Topics: Inositol; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Molecular Structure; Organothiophosphorus Compounds | 1994 |
Sulfhydryl reagents and cAMP-dependent kinase increase the sensitivity of the inositol 1,4,5-trisphosphate receptor in hepatocytes.
Topics: Animals; Bucladesine; Calcium; Calcium Channels; Cell Membrane Permeability; Cells, Cultured; Fura-2; Guinea Pigs; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Isoproterenol; Kinetics; Liver; Oxidants; Peroxides; Protein Kinases; Rats; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Sulfhydryl Reagents; tert-Butylhydroperoxide | 1993 |
Ins(1,3,4,5)P4 is effective in mobilizing Ca2+ in mouse exocrine pancreatic acinar cells if phospholipase A2 is inhibited.
Topics: Acetophenones; Animals; Arachidonic Acid; Calcium; Cells, Cultured; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Membrane Potentials; Mice; Pancreas; Patch-Clamp Techniques; Phospholipases A; Phospholipases A2; Thapsigargin | 1996 |
Rapid kinetic measurements of 45Ca2+ mobilization reveal that Ins(2,4,5)P3 is a partial agonist at hepatic InsP3 receptors.
Topics: Animals; Calcium; Calcium Channels; Cells, Cultured; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Kinetics; Liver; Permeability; Rats; Receptors, Cytoplasmic and Nuclear | 1997 |
Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
Topics: Animals; Binding Sites; Calcium; Catalysis; Crystallography, X-Ray; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Isoenzymes; Molecular Sequence Data; Phosphatidylinositol 4,5-Diphosphate; Phospholipase C delta; Rats; Structure-Activity Relationship; Substrate Specificity; Type C Phospholipases | 1997 |
Kinetics of elementary Ca2+ puffs evoked in Xenopus oocytes by different Ins(1,4,5)P3 receptor agonists.
Topics: Adenosine; Animals; Calcium Channels; Calcium Signaling; Cerebellum; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Kinetics; Microscopy, Confocal; Oocytes; Rats; Receptors, Cytoplasmic and Nuclear; Xenopus laevis | 1998 |
Effect of adenophostin A on Ca2+ entry and calcium release-activated calcium current (Icrac) in rat basophilic leukemia cells.
Topics: Adenosine; Animals; Barium; Calcium; Calcium Channels; Egtazic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Leukemia, Basophilic, Acute; Rats; Time Factors; Tumor Cells, Cultured | 1998 |
High efficient expression of the functional ligand binding site of the inositol 1,4,5-triphosphate receptor in Escherichia coli.
Topics: Amino Acid Substitution; Animals; Binding Sites; Blotting, Western; Calcium Channels; Escherichia coli; Heparin; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Kinetics; Ligands; Mice; Peptide Fragments; Phosphatidylinositol 4,5-Diphosphate; Phytic Acid; Protein Conformation; Protein Folding; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Sequence Deletion; Solubility | 1999 |
The effect of inositol 1,3,4,5-tetrakisphosphate on inositol trisphosphate-induced Ca2+ mobilization in freshly isolated and cultured mouse lacrimal acinar cells.
Topics: Acetylcholine; Animals; Calcium; Cells, Cultured; Chloride Channels; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Lacrimal Apparatus; Male; Mice; Potassium Channels; Time Factors | 2000 |
Functional properties of Drosophila inositol trisphosphate receptors.
Topics: Adenosine; Animals; Binding, Competitive; Calcium; Calcium Channels; Calcium Signaling; Cell Line; Drosophila; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Intracellular Fluid; Kinetics; Mammals; Receptors, Cytoplasmic and Nuclear | 2001 |
Adenophostin A and ribophostin, but not inositol 1,4,5-trisphosphate or manno-adenophostin, activate the Ca2+ release-activated Ca2+ current, I(CRAC), in weak intracellular Ca2+ buffer.
Topics: Adenosine; Adenosine Triphosphate; Animals; Buffers; Calcium Channel Agonists; Calcium Channels; Calcium Signaling; Disaccharides; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Intracellular Fluid; Mitochondria; Patch-Clamp Techniques; Rats; Sugar Phosphates; Tumor Cells, Cultured | 2002 |
X-ray structure of the R69D phosphatidylinositol-specific phospholipase C enzyme: insight into the role of calcium and surrounding amino acids in active site geometry and catalysis.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Bacillus cereus; Bacillus thuringiensis; Binding Sites; Calcium; Catalysis; Crystallization; Crystallography, X-Ray; Histidine; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Molecular Sequence Data; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide Phospholipase C; Rats; Stereoisomerism | 2005 |
Quantal Ca
Topics: Animals; Calcium; Calcium Signaling; Chickens; Drug Partial Agonism; Endoplasmic Reticulum; HEK293 Cells; Humans; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Inositol Phosphates; Time Factors | 2021 |