indomethacin has been researched along with metyrapone in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 8 (38.10) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 6 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Parnham, MJ; Sneddon, JM | 1 |
| Campbell, WB; Pfister, SL | 1 |
| Gebel, T; Maser, E; Netter, KJ | 1 |
| Coceani, F; De Marte, J; Perreault, T | 1 |
| Campbell, WB; Falck, JR; Pfister, SL | 1 |
| Aguila, MC; McCann, SM; Milenkovic, L; Snyder, GD | 1 |
| Fuchimoto, S; Orita, K; Shiiki, S | 1 |
| Hertting, G; Okajima, T | 1 |
| Berlin, T; Larsson, R; Moldéus, P; Olsson, LI; Ross, D | 1 |
| Mécs, I; Selye, H | 1 |
| Karis, MA; Menzel, DB; Williams, SJ | 1 |
| Coceani, F; Hamilton, NC; Labuc, J; Olley, PM | 1 |
| Huang, H; Jurima-Romet, M; Paul, CJ; Solomonraj, G; Thomas, BH | 1 |
| Forsling, ML; Goode, JA; Lloyd, DM; Parrott, RF; Vellucci, SV | 1 |
| Cadirci, E; Gocer, F; Hacimuftuoglu, A; Halici, Z; Keles, S; Suleyman, H | 1 |
| Bagaeva, TR; Bobryshev, PIu; Filaretova, LP | 1 |
| Bagaeva, TR; Filaretova, LP; Miazina, MA | 1 |
1 review(s) available for indomethacin and metyrapone
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
20 other study(ies) available for indomethacin and metyrapone
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The influence of metyrapone on the synthesis and release of prostaglandins from the pregnant rat uterus in vitro.
Topics: Animals; Female; Indomethacin; Metyrapone; Pregnancy; Pregnancy, Animal; Prostaglandin-Endoperoxide Synthases; Prostaglandins E; Prostaglandins F; Rats; Uterine Contraction; Uterus | 1975 |
Arachidonic acid- and acetylcholine-induced relaxations of rabbit aorta.
Topics: Acetylcholine; Animals; Aorta; Arachidonic Acid; Arginine; Bridged Bicyclo Compounds, Heterocyclic; Cyclic GMP; Fatty Acids, Unsaturated; Hydrazines; Indomethacin; Male; Masoprocol; Metyrapone; Nitroarginine; Rabbits; Receptors, Thromboxane; Vasodilation | 1992 |
Carbonyl reduction of metyrapone in human liver.
Topics: Alcohol Oxidoreductases; Dicumarol; Dihydrotestosterone; Female; Humans; Immune Sera; Immunoblotting; Indomethacin; Liver; Male; Metyrapone; Oxidation-Reduction; Quercetin; Subcellular Fractions | 1991 |
Evidence against the involvement of a cytochrome P-450 mechanism in pulmonary hemodynamics in the newborn pig.
Topics: Animals; Animals, Newborn; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Indomethacin; Isoenzymes; Ketoconazole; Lipoxygenase Inhibitors; Metyrapone; Perfusion; Pulmonary Circulation; Swine | 1991 |
Enhanced synthesis of epoxyeicosatrienoic acids by cholesterol-fed rabbit aorta.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 6-Ketoprostaglandin F1 alpha; 8,11,14-Eicosatrienoic Acid; Animals; Aorta, Thoracic; Arachidonic Acids; Carbon Radioisotopes; Cholesterol, Dietary; Clotrimazole; Diet, Atherogenic; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Indomethacin; Kinetics; Masoprocol; Metyrapone; Muscle, Smooth, Vascular; Rabbits; Reference Values; Stereoisomerism | 1991 |
Role of arachidonic acid or its metabolites in growth-hormone-releasing factor-induced release of somatostatin from the median eminence.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Growth Hormone-Releasing Hormone; Indomethacin; Kinetics; Lipoxygenase Inhibitors; Male; Masoprocol; Median Eminence; Metyrapone; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Rats, Inbred Strains; Somatostatin | 1990 |
A comparison of the antitumor effects of natural human tumor necrosis factors alpha and beta: the roles of arachidonic acid metabolism and intracellular cAMP.
Topics: Arachidonic Acid; Arachidonic Acids; Breast Neoplasms; Colforsin; Colonic Neoplasms; Cyclic AMP; Dexamethasone; Female; Humans; Indomethacin; Lymphotoxin-alpha; Metyrapone; Phospholipases A; Phospholipases A2; Quinacrine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1990 |
The possible involvement of cytochrome P-450 monooxygenase in AVP-induced ACTH secretion.
Topics: Adrenocorticotropic Hormone; Animals; Arachidonic Acid; Arachidonic Acids; Arginine Vasopressin; Benzoflavones; Cytochrome P-450 Enzyme System; Dinoprostone; Indomethacin; Male; Metyrapone; Oxygenases; Piperonyl Butoxide; Pituitary Gland, Anterior; Prostaglandins E; Rats; Rats, Inbred Strains | 1986 |
Prostaglandin synthase catalyzed metabolic activation of p-phenetidine and acetaminophen by microsomes isolated from rabbit and human kidney.
Topics: Acetaminophen; Aminophenols; Animals; Arachidonic Acid; Arachidonic Acids; Glutathione; Glutathione Disulfide; Humans; Indomethacin; Kidney; Kinetics; Linolenic Acids; Lipid Peroxides; Male; Metyrapone; Microsomes; Models, Chemical; NADP; Phenetidine; Proadifen; Prostaglandin-Endoperoxide Synthases; Protein Binding; Rabbits | 1985 |
Blockade of catatoxic steroid actions by metyrapone.
Topics: Adrenocorticotropic Hormone; Animals; Digitoxin; Female; Indomethacin; Metyrapone; Peptic Ulcer; Rats; Spironolactone | 1970 |
Interactions of heavy metals with the pulmonary metabolism of [3H]benzo[a]pyrene.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Biotransformation; Cadmium; Cadmium Chloride; Chromatography, High Pressure Liquid; Cobalt; Drug Interactions; Indomethacin; Lung; Male; Metyrapone; Nickel; Rats; Rats, Inbred Strains; Tritium | 1984 |
Cytochrome P 450-linked monooxygenase: involvement in the lamb ductus arteriosus.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ductus Arteriosus; Female; Guinea Pigs; Indomethacin; Metyrapone; Muscle Contraction; Oxygen; Oxygenases; Photic Stimulation; Pregnancy; Sheep | 1984 |
Metabolism of phenazopyridine by isolated rat hepatocytes.
Topics: Animals; Benzoflavones; Detergents; Enzyme Induction; In Vitro Techniques; Indomethacin; Liver; Male; Metyrapone; Octoxynol; Phenazopyridine; Polyethylene Glycols; Proadifen; Rats; Rats, Wistar | 1993 |
Interrelated adrenocortical and neurohypophysial responses associated with fever in endotoxin-treated pigs.
Topics: Analgesics, Non-Narcotic; Animals; Body Temperature Regulation; Dexamethasone; Endotoxins; Escherichia coli; Fever; Genes, fos; Hydrocortisone; Indomethacin; Lipopolysaccharides; Lypressin; Male; Metyrapone; Oxytocin; Pituitary-Adrenal System; Proto-Oncogene Proteins c-fos; Swine; Time Factors | 1997 |
Indirect role of alpha2-adrenoreceptors in anti-ulcer effect mechanism of nimesulide in rats.
Topics: Adrenalectomy; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; alpha-Methyltyrosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Corticosterone; Desoxycorticosterone; Dose-Response Relationship, Drug; Doxazosin; Epinephrine; Indomethacin; Male; Metyrapone; Prednisolone; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-2; Stomach Ulcer; Sulfonamides; Yohimbine | 2007 |
[Contribution of glucocorticoid hormones to gastroprotective effect of ischemic preconditioning in rats with normal and deficient prostaglandin production].
Topics: Adrenalectomy; Animals; Corticosterone; Gastric Mucosa; Glucocorticoids; Indomethacin; Ischemic Preconditioning; Male; Metyrapone; Prostaglandin Antagonists; Prostaglandins; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Stomach | 2010 |
[Metyrapone effect on gastroprotective action of corticotropin-releasing factor administered centrally against indomethacin-induced gastric injury].
Topics: Animals; Corticosterone; Corticotropin-Releasing Hormone; Gastric Mucosa; Glucocorticoids; Indomethacin; Male; Metyrapone; Rats; Stomach Ulcer | 2014 |