indomethacin has been researched along with lysine in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (26.00) | 18.7374 |
| 1990's | 18 (36.00) | 18.2507 |
| 2000's | 14 (28.00) | 29.6817 |
| 2010's | 4 (8.00) | 24.3611 |
| 2020's | 1 (2.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Cioffi, A; Conte, F; Di Belgiojoso, GB; Donati, MB; Saruggia, M; Sessa, A | 1 |
| Roosdorp, N; Sjöholm, I; Wänn, B | 1 |
| Arnold, J; Catania, A; Hiltz, ME; Lipton, JM; Macaluso, A | 1 |
| Blomgren, H; Hammarström, S; Petrini, B; Rotstein, S; Wasserman, J | 1 |
| Crivellari, MT; Folco, GC; Galli, G; Ortolani, C; Sala, A; Viganò, T | 1 |
| Arrigoni Martelli, E; Colombo, P; Conte, U; La Manna, A; Marzo, A; Reiner, A | 1 |
| Bettini, V; Martino, R; Tegazzin, V; Ton, P | 1 |
| Bettini, V; Calò, L; Cantaro, S; Martino, R; Munari, L; Salvatico, E; Ton, P | 1 |
| Alburn, HE; Dougherty, JA; Fenichel, RL | 1 |
| Corzo, J; Fremont-Smith, M; Guarner, F; Prieto, J; Quiroga, J; Rodriguez, JL | 1 |
| Bettini, V; Gamba, G; Legrenzi, E; Mayellaro, F; Santoni, G | 1 |
| Castellani, S; Mannelli, M; Masotti, G; Neri Serneri, GG; Scarti, L; Trotta, F | 1 |
| Alessandrini, A; Gemini, R | 1 |
| Barabino, A; Corsini, G; Puppo, F; Zavarise, GM | 1 |
| Bettini, V; Calcagno, A; Legrenzi, E; Mayellaro, F; Pilastro, G | 1 |
| Atkins, DJ; Meyer zum Gottesberge, A; Nagyiványi, P; Pallapies, D; Peskar, BA; Rohleder, G; Salinger, A | 1 |
| Abe, Y; Aki, Y; Kimura, S; Takenaka, I; Tamaki, T; Yoshida, H | 1 |
| Dauksas, V; Gaidelis, P; Kuliesius, V; Labanauskas, L; Udrènaitè, E | 1 |
| Berni, F; Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A | 1 |
| Akkerman, JW; Gorter, G; van Willigen, G | 1 |
| Higuchi, T; Imamura, Y; Otagiri, M | 1 |
| Brouckaert, P; Fiers, W; Takahashi, N | 1 |
| Knox, A; Pavord, I; Tattersfield, A; Wang, M; Wisniewski, A | 1 |
| al-Sahlawi, KS; Tawfik, OM | 1 |
| Hangaishi, M; Hashimoto, Y; Ikari, Y; Kimura, S; Kurokawa, K; Miyata, T; Ohno, M; Taguchi, J; Togo, M; Watanabe, T | 1 |
| de los Santos, AR; Di Girolamo, G; Franchi, A; Gimeno, MA; Marti, ML | 1 |
| de los Santos, AR; Di Girolamo, G; Franchi, AM; Gimeno, MA; Martí, ML | 1 |
| Bianco, S; Pieroni, MG; Refini, RM; Robuschi, M; Sestini, P; Vaghi, A | 1 |
| Honoré, B; Qasim, MA; Trivedi, VD; Vorum, H | 1 |
| Aziz, MA; Haq, SK; Khan, MM; Muzammil, S; Tayyab, S | 1 |
| Branco, LG; Steiner, AA | 1 |
| Bayer, T; Beyreuther, K; Fassbender, K; Hartmann, T; Hennerici, M; Ishii, K; Kühl, S; Liebl, U; Muelhauser, F; Penke, B; Picard, M; Wiessler, M | 1 |
| Ates, M; Brune, K; Coste, O; Görig, M; Gühring, H; Pahl, A; Rehse, K; Zeilhofer, HU | 1 |
| de los Santos, AR; Di Girolamo, G; Farina, M; Franchi, A; Gimeno, MA; Martí, ML | 1 |
| Fedinec, AL; Johnson, RA; Leffler, CW; Nasjletti, A | 1 |
| de los Santos, AR; Di Girolamo, G; Farina, M; Franchi, AM; Gimeno, MA; Martí, ML | 1 |
| Berens, ME; Djawaheri, J; Giese, A; Hagel, C; Kim, EL; Westphal, M; Zapf, S | 1 |
| De Los Santos, AR; Di Girolamo, G; Farina, M; Fernández de Gimeno, MA; Franchi, A; Martí, ML | 1 |
| Fuseler, J; Grisham, M; Roerig, SC; Tedesco, LS; Wolf, R | 1 |
| Bryant, CD; Chesler, EJ; Giles, BE; Lariviere, WR; Mogil, JS; Olsen, MS; Wilson, SG | 1 |
| Kozak, W; Szefer, M; Terlecki, P; Walentynowicz, K; Wojtal, B; Wrotek, S | 1 |
| Butler, BD; Little, T | 1 |
| Corff, KE; Sekar, KC | 1 |
| Hausmann, M; Hu, WC; Karpitschka, M; Kasparek, MS; Kreis, ME; Müller, MH; Pesch, T; Rogler, G; Sibaev, A; Xue, B | 1 |
| ElShaer, A; Hanson, P; Mohammed, AR | 1 |
| Blaabjerg, LI; Bohr, A; Grohganz, H; Jensen, KT; Kleinebudde, P; Lenz, E; Löbmann, K; Rades, T | 1 |
| Grohganz, H; Kasten, G; Löbmann, K; Nouri, K; Rades, T | 1 |
| Gong, Y; Liu, NF; Liu, XY; Peng, KF; Xu, W; Yang, XW; Yang, YF; Zhang, P; Zhang, YB; Zhao, W | 1 |
1 review(s) available for indomethacin and lysine
| Article | Year |
|---|---|
Treatment of patent ductus arteriosus: indomethacin or ibuprofen?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Lysine | 2008 |
5 trial(s) available for indomethacin and lysine
| Article | Year |
|---|---|
[Comparative clinical study of the efficacy of and tolerance for lysine para-isobutylphenyl propionate in parallel with indomethacin and pyrasanone].
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Drug Tolerance; Female; Humans; Ibuprofen; Indomethacin; Lysine; Male; Middle Aged; Phenylbutazone; Rheumatic Diseases; Time Factors | 1980 |
Potentiation of the antireactive, antiasthmatic effect of inhaled furosemide by inhaled lysine acetylsalicylate.
Topics: Administration, Inhalation; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperreactivity; Double-Blind Method; Drug Synergism; Female; Forced Expiratory Volume; Furosemide; Humans; Indomethacin; Lysine; Male; Middle Aged | 1993 |
Comparison of three inhaled non-steroidal anti-inflammatory drugs on the airway response to sodium metabisulphite and adenosine 5'-monophosphate challenge in asthma.
Topics: Adenosine Monophosphate; Administration, Inhalation; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstrictor Agents; Double-Blind Method; Female; Humans; Hydrogen-Ion Concentration; Indomethacin; Lung; Lysine; Male; Middle Aged; Osmolar Concentration; Sodium Salicylate; Sulfites | 1996 |
Comparative study of the efficacy of lysine acetylsalicylate, indomethacin and pethidine in acute renal colic.
Topics: Adult; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Colic; Double-Blind Method; Female; Humans; Indomethacin; Kidney Diseases; Lysine; Male; Meperidine; Middle Aged; Pain Measurement; Time Factors | 1996 |
Different effects of inhaled aspirinlike drugs on allergen-induced early and late asthmatic responses.
Topics: Administration, Inhalation; Adolescent; Adult; Allergens; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Indomethacin; Lysine; Male; Sodium Salicylate | 1999 |
44 other study(ies) available for indomethacin and lysine
| Article | Year |
|---|---|
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Indomethacin and lysine acetylsalicylate in rats with autologous nephrotoxic serum nephritis. Biochemical and morphological studies.
Topics: Animals; Aspirin; Basement Membrane; Disease Models, Animal; Female; Glomerulonephritis; Immune Sera; Indomethacin; Kidney Glomerulus; Lysine; Proteinuria; Rabbits; Rats | 1978 |
Correlation between arginyl residue modification and benzodiazepine binding to human serum albumin.
Topics: Arginine; Bilirubin; Binding Sites; Cyclohexanones; Diazepam; Humans; Imidazoles; Indomethacin; Lysine; Phenylbutazone; Protein Binding; Protein Conformation; Serum Albumin; Tyrosine | 1977 |
Inhibition of acute inflammation in the periphery by central action of salicylates.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dexamethasone; Female; Indomethacin; Inflammation; Injections, Intraperitoneal; Injections, Intraventricular; Lysine; Mice; Mice, Inbred BALB C; Sodium Salicylate | 1991 |
In vitro capacity of various cyclooxygenase inhibitors to revert immune suppression caused by radiation therapy for breast cancer.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Breast Neoplasms; Cyclooxygenase Inhibitors; Diclofenac; Female; Humans; Immune Tolerance; In Vitro Techniques; Indomethacin; Ketoprofen; Lymphocyte Activation; Lysine; Meclofenamic Acid; Middle Aged; Phytohemagglutinins | 1990 |
On the mechanism of aspirin asthma.
Topics: Aspirin; Asthma; Humans; In Vitro Techniques; Indomethacin; Leukotrienes; Lung; Lysine | 1989 |
Bioavailability of indomethacin from a modified release system containing indomethacin as the lysine salt.
Topics: Biological Availability; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Female; Humans; Indomethacin; Kinetics; Lysine; Male | 1987 |
[Contractile response of segments of the coronary arteries to histamine and angiotensin II in the presence of anthocyanosides of myrtillus].
Topics: Angiotensin II; Animals; Anthocyanins; Aspirin; Cattle; Coronary Vessels; Histamine Antagonists; Indomethacin; Lysine; Plants; Vasoconstriction | 1987 |
Liberation of prostaglandin-like substances from the isolated coronary artery in presence of angiotensin and of 4-methylesculetin.
Topics: Angiotensin II; Animals; Ascorbic Acid; Aspirin; Cattle; Coronary Vessels; Drug Interactions; In Vitro Techniques; Indomethacin; Lysine; Muscle, Smooth, Vascular; Prostaglandins; Scopoletin; Umbelliferones | 1985 |
Inhibition of platelet aggregation by 2-(p-chlorophenyl)-4-thiazoleacrylic acid (Wy-23,049)--comparison with acetylsalicylic acid.
Topics: Acrylates; Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Chlorobenzenes; Collagen; Cyclic AMP; Humans; In Vitro Techniques; Indomethacin; Lysine; Platelet Adhesiveness; Platelet Aggregation; Polymers; Prostaglandins; Rats; Rats, Inbred Strains; Thiazoles; Time Factors | 1974 |
In vivo and in vitro effects of arachidonic acid products on liver cell integrity following carbon tetrachloride poisoning.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Alanine Transaminase; Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Aspirin; Carbon Tetrachloride Poisoning; Epoprostenol; Female; Indomethacin; Liver; Lysine; Peroxides; Prostaglandins; Pyrazoles; Rats; Rats, Inbred Strains | 1983 |
[Responses of isolated hepatic artery segments to barium in the presence of a flavonoid (4-methylesculetin), indomethacin and acetylsalicylate].
Topics: Animals; Aspirin; Barium; Hepatic Artery; Indomethacin; Lysine; Muscle Contraction; Scopoletin; Sheep; Umbelliferones | 1983 |
Role of PGE2 in the modulation of the adrenergic response in man.
Topics: Adult; Aspirin; Cold Temperature; Dinoprost; Dinoprostone; Epinephrine; Female; Humans; Indomethacin; Lysine; Male; Norepinephrine; Prostaglandins E; Prostaglandins F; Sympathetic Nervous System; Vascular Resistance | 1983 |
[Evaluation of the effect of ibuprofen lysinate on lymphocytic transformation in vitro. Comparison with meglumine indomethacinate, phenylbutazone, and lysine acetylsalicylate].
Topics: Anti-Inflammatory Agents; Aspirin; Humans; Ibuprofen; Indomethacin; Lymphocyte Activation; Lysine; Meglumine; Phenylbutazone | 1980 |
[Effect of prostaglandin-synthetase inhibitors on responses of segments of coronary arteries to 4-methylesculetol and/or to angiotensin II].
Topics: Angiotensin II; Animals; Ascorbic Acid; Aspirin; Cattle; Coronary Vessels; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Indomethacin; Lysine; Muscle, Smooth, Vascular; Scopoletin; Umbelliferones | 1981 |
Effects of lysine clonixinate and ketorolac tromethamine on prostanoid release from various rat organs incubated ex vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Clonixin; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Drug Combinations; Gastric Mucosa; Indomethacin; Isoenzymes; Ketorolac Tromethamine; Kidney; Lung; Lysine; Male; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Wistar; Thromboxane B2; Tolmetin; Tromethamine | 1995 |
Effects of angiotensin II on isolated rabbit afferent arterioles.
Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arterioles; Aspirin; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Lysine; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Antagonists; Prostaglandins; Rabbits; Renal Circulation; Tetrazoles; Vascular Resistance | 1994 |
Synthesis and anti-inflammatory properties of 1,2-dialkoxy-4-(3-dimethylaminopropionyl)benzenes and their 5-halogeno derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Edema; Foot Injuries; Indomethacin; Lethal Dose 50; Lysine; Male; Mice; Mice, Inbred BALB C; Peritonitis; Propiophenones; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship | 1994 |
LDLs increase the exposure of fibrinogen binding sites on platelets and secretion of dense granules.
Topics: Adenosine Diphosphate; Binding Sites; Blood Platelets; Cytoplasmic Granules; Fibrinogen; Humans; Indomethacin; Lipoproteins, HDL; Lipoproteins, LDL; Lysine; Platelet Aggregation; Platelet Membrane Glycoproteins; Serotonin; Thrombin | 1994 |
Chemical modification of arginine and lysine residues in coenzyme-binding domain of carbonyl reductase from rabbit kidney: indomethacin affords a significant protection against inactivation of the enzyme by phenylglyoxal.
Topics: Alcohol Oxidoreductases; Animals; Arginine; Enzyme Activation; Indomethacin; Kidney; Lysine; NADP; Phenylglyoxal; Rabbits; Trinitrobenzenesulfonic Acid | 1994 |
Cyclooxygenase inhibitors prevent the induction of tolerance to the toxic effects of tumor necrosis factor.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Protocols; Combined Modality Therapy; Cyclooxygenase Inhibitors; Drug Interactions; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Immunotherapy; Indomethacin; Lysine; Mice; Mice, Inbred C57BL; Neoplasms; Piroxicam; Recombinant Proteins; Tumor Necrosis Factor-alpha | 1993 |
Increased aggregation of human platelets produced by advanced glycation end products in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Arginine; Arteriosclerosis; Cyclic AMP; Cyclic GMP; Female; Glycation End Products, Advanced; Humans; Indomethacin; Lysine; Male; Oxidative Stress; Platelet Aggregation; Polylysine; Prostaglandins; Reactive Oxygen Species; Serum Albumin, Bovine; Superoxide Dismutase; Superoxides | 1998 |
[Effect of lysine clonixinate and indomethacin on lipoxygenase and cyclooxygenase activity in colon isolated from cancer patients].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Colon; Colonic Neoplasms; Cyclooxygenase Inhibitors; Gastric Mucosa; Humans; Indomethacin; Lipoxygenase Inhibitors; Lysine; Prostaglandin-Endoperoxide Synthases | 1998 |
Effects of lysine clonixinate on cyclooxygenase I and II in rat lung and stomach preparations.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Clonixin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Isoenzymes; Lung; Lysine; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Stomach; Thromboxane B2 | 1998 |
Molecular basis of indomethacin-human serum albumin interaction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Humans; Hydrogen-Ion Concentration; Indomethacin; Lysine; Serum Albumin; Spectrometry, Fluorescence | 1999 |
Effect of lysine modification on the conformation and indomethacin binding properties of human serum albumin.
Topics: Acetic Anhydrides; Binding Sites; Cardiovascular Agents; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Fluorescence; Humans; Hydrogen-Ion Concentration; Indomethacin; Lysine; Methylurea Compounds; Osmolar Concentration; Protein Conformation; Serum Albumin; Succinic Anhydrides | 1999 |
Central CO-heme oxygenase pathway raises body temperature by a prostaglandin-independent way.
Topics: Animals; Body Temperature; Carbon Monoxide; Central Nervous System; Cyclooxygenase Inhibitors; Deuteroporphyrins; Dinoprostone; Enzyme Inhibitors; Fever; Heme; Heme Oxygenase (Decyclizing); Indomethacin; Injections, Intraperitoneal; Injections, Intraventricular; Lipopolysaccharides; Lysine; Male; Prostaglandins; Rats; Rats, Wistar; Time Factors | 2000 |
Subacute NO generation induced by Alzheimer's beta-amyloid in the living brain: reversal by inhibition of the inducible NO synthase.
Topics: Amyloid beta-Peptides; Animals; Brain; Cells, Cultured; Indomethacin; Interferon-gamma; Kinetics; Lysine; Mice; Mice, Inbred BALB C; Microglia; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Peptide Fragments; Plaque, Amyloid | 2000 |
Suppressed injury-induced rise in spinal prostaglandin E2 production and reduced early thermal hyperalgesia in iNOS-deficient mice.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hot Temperature; Hyperalgesia; Indomethacin; Isoenzymes; Lysine; Membrane Proteins; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pain; Prostaglandin-Endoperoxide Synthases; Spinal Cord; Sydnones; Transcription, Genetic; Zymosan | 2000 |
[Differential action of non-steroidal antiinflammatory drugs on human gallbladder cyclooxygenase and lipoxygenase].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Clonixin; Gallbladder; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Lysine; Prostaglandins | 2000 |
Contributions of prostacyclin and nitric oxide to carbon monoxide-induced cerebrovascular dilation in piglets.
Topics: Animals; Animals, Newborn; Arterioles; Carbon Monoxide; Heme; Indomethacin; Kinetics; Lysine; Microcirculation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Peptides; Pia Mater; Potassium Channels; Scorpion Venoms; Swine; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2001 |
In vivo and in vitro effects of lysine clonixinate on nitric oxide synthase in LPS-treated and untreated rat lung preparations.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Clonixin; Indomethacin; Lipopolysaccharides; Lung; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar | 2001 |
Thromboxane synthase regulates the migratory phenotype of human glioma cells.
Topics: Arachidonic Acids; Aspirin; Astrocytes; Benzofurans; Brain Neoplasms; Cell Adhesion; Cell Movement; Enzyme Induction; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; GTP-Binding Proteins; Humans; Imidazoles; Indomethacin; Lysine; Models, Biological; Neoplasm Proteins; Neoplastic Stem Cells; Oligodendroglia; Pentanoic Acids; Phenotype; Pyridines; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Thromboxane B2; Thromboxane-A Synthase; Tumor Cells, Cultured | 1999 |
[Effect of nonsteroidal antiinflammatory drugs on colonic lipoxygenase and cyclooxygenase activities from patients with colonic neoplasia].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Clonixin; Colon; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Isoenzymes; Lipoxygenase Inhibitors; Lysine; Membrane Proteins; Prostaglandin-Endoperoxide Synthases | 2001 |
Therapeutic administration of nitric oxide synthase inhibitors reverses hyperalgesia but not inflammation in a rat model of polyarthritis.
Topics: Animals; Arthritis; Body Weight; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Female; Hot Temperature; Hyperalgesia; Indomethacin; Lysine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Physical Stimulation; Rats; Rats, Inbred Lew | 2002 |
The heritability of antinociception II: pharmacogenetic mediation of three over-the-counter analgesics in mice.
Topics: Acetaminophen; Acetic Acid; Analgesics, Non-Narcotic; Animals; Aspirin; Dose-Response Relationship, Drug; Female; Hot Temperature; Indomethacin; Lysine; Male; Mice; Mice, Inbred Strains; Nociceptors; Pain Measurement; Pharmacogenetics; Reaction Time; Species Specificity | 2003 |
Role of prostaglandins in heme-induced fever.
Topics: Animals; Body Temperature; Brain; Dinoprostone; Dose-Response Relationship, Drug; Fever; Heme; Immunoglobulin G; Immunoglobulins; Indomethacin; Injections, Intraventricular; Lysine; Male; Rats; Rats, Sprague-Dawley | 2006 |
Pharmacological intervention to the inflammatory response from decompression sickness in rats.
Topics: Animals; Cyclooxygenase Inhibitors; Decompression Sickness; Hydroxyurea; Indoles; Indomethacin; Inflammation; Isoproterenol; Lipoxygenase Inhibitors; Lysine; Male; Phenylcarbamates; Pulmonary Edema; Rats; Rats, Sprague-Dawley; Sulfonamides; Tosyl Compounds | 2008 |
Afferent nerve sensitivity is decreased by an iNOS-dependent mechanism during indomethacin-induced inflammation in the murine jejunum in vitro.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bradykinin; Electrophysiology; Humans; Indomethacin; Inflammation; Jejunum; Lysine; Male; Mice; Mice, Inbred C57BL; Neurons, Afferent; Nitric Oxide Synthase Type II; Serotonin | 2009 |
A novel concentration dependent amino acid ion pair strategy to mediate drug permeation using indomethacin as a model insoluble drug.
Topics: 1-Octanol; Arginine; Caco-2 Cells; Humans; Indomethacin; Lysine; Permeability; Solubility; Water | 2014 |
Preparation and characterization of spray-dried co-amorphous drug-amino acid salts.
Topics: Aerosols; Amino Acids; Arginine; Calorimetry, Differential Scanning; Crystallization; Crystallography, X-Ray; Desiccation; Drug Compounding; Drug Stability; Freeze Drying; Histidine; Indomethacin; Kinetics; Lysine; Powder Diffraction; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Thermogravimetry; Transition Temperature | 2016 |
Performance comparison between crystalline and co-amorphous salts of indomethacin-lysine.
Topics: Calorimetry, Differential Scanning; Crystallization; Drug Compounding; Drug Stability; Indomethacin; Lysine; Powder Diffraction; Salts; Spectroscopy, Fourier Transform Infrared; Temperature; X-Ray Diffraction | 2017 |
Anti-Inflammatory Activity of Some Characteristic Constituents from the Vine Stems of
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Fabaceae; Gene Expression; Glycosides; Humans; Indomethacin; Inhibitory Concentration 50; Lipopolysaccharides; Lysine; Medicine, Chinese Traditional; Mice; Nitric Oxide; Nitric Oxide Synthase Type II; Plant Extracts; Plant Stems; RAW 264.7 Cells; Tumor Necrosis Factor-alpha | 2019 |