indomethacin and heme

indomethacin has been researched along with heme in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's5 (33.33)18.2507
2000's4 (26.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hayaishi, O; Miyamoto, T; Ogino, N; Yamamoto, S1
Hong, S; Levine, L; Polsky-Cynkin, R1
Walker, SM1
Saeed, SA; Warren, BT1
Gerrard, JM; Mills, EL; Peterson, DA; Rao, GH; White, JG1
DeWitt, DL; Otto, JC; Smith, WL1
Marnett, LJ; Wells, I1
Baek, HK; Kulmacz, RJ; Tsai, Al; Van Wart, HE; Wei, C1
Kihara, T; Nagamatsu, A; Ono, N; Shimeno, H; Toda, A1
Basu-Modak, S; Kvam, E; Noel, A; Tyrrell, RM1
Branco, LG; Steiner, AA1
Fedinec, AL; Johnson, RA; Leffler, CW; Nasjletti, A1
Kulmacz, RJ; Osawa, Y; Tsai, AL; Vuletich, JL; Wu, G1
Kozak, W; Szefer, M; Terlecki, P; Walentynowicz, K; Wojtal, B; Wrotek, S1
Dong, L; Jurban, BJ; Sharma, NP; Smith, WL1

Other Studies

15 other study(ies) available for indomethacin and heme

ArticleYear
Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes.
    The Journal of biological chemistry, 1976, May-10, Volume: 251, Issue:9

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Cattle; Heme; Indomethacin; Kinetics; Male; Microsomes; Mixed Function Oxygenases; Prostaglandin-Endoperoxide Synthases; Seminal Vesicles; Structure-Activity Relationship

1976
The effects of hydroquinone, hematin and heme-containing proteins on prostaglandin biosynthesis by methylcholanthrene-transformed mouse BALB/3T3 fibroblasts.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 197, Issue:3

    Topics: Animals; Arachidonic Acids; Cell Transformation, Neoplastic; Cells, Cultured; Fibroblasts; Glutathione; Heme; Hemeproteins; Hemin; Hemoglobins; Hydroquinones; Indomethacin; Methylcholanthrene; Mice; Mice, Inbred BALB C; Porphyrins; Prostaglandins; Stimulation, Chemical

1976
Abrogation of macrophage-mediated suppression of T-lymphocyte proliferation with hemoglobin and hemin is a function of iron content.
    Cellular immunology, 1985, Volume: 90, Issue:1

    Topics: Animals; Heme; Hemin; Hemoglobins; Hypersensitivity, Delayed; Immune Tolerance; Indomethacin; Iron; Lymphocyte Activation; Macrophages; Male; Mice; Mice, Inbred Strains; Peritoneal Cavity; Spleen

1985
On the mode of action and biochemical properties of anti-inflammatory drugs. I.
    Biochemical pharmacology, 1973, Aug-15, Volume: 22, Issue:16

    Topics: Acetamides; Anti-Inflammatory Agents; Heme; Indomethacin; Kinetics; Mefenamic Acid; Oxidation-Reduction; Oxyphenbutazone; Peroxidases; Phenylbutazone; Plants; Protein Denaturation; Spectrophotometry

1973
Interaction of arachidonic acid and heme iron in the synthesis of prostaglandins.
    Advances in prostaglandin and thromboxane research, 1980, Volume: 6

    Topics: Animals; Arachidonic Acids; Binding Sites; Blood Platelets; Heme; Indomethacin; Iron; Molecular Conformation; Prostaglandin-Endoperoxide Synthases; Prostaglandins

1980
N-glycosylation of prostaglandin endoperoxide synthases-1 and -2 and their orientations in the endoplasmic reticulum.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Western; Cell Line; Conserved Sequence; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Glycosylation; Heme; Indomethacin; Intracellular Membranes; Isoenzymes; Mice; Microsomes; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Mapping; Peroxidases; Prostaglandin-Endoperoxide Synthases; Protein Conformation; Restriction Mapping; Sheep; Transfection; Trypsin

1993
Inactivation of prostaglandin endoperoxide synthase by acylating derivatives of indomethacin.
    Biochemistry, 1993, Mar-16, Volume: 32, Issue:10

    Topics: Acylation; Animals; Cyclooxygenase Inhibitors; Enzyme Activation; Heme; Hydroxylamine; Hydroxylamines; Imidazoles; Indicators and Reagents; Indomethacin; Kinetics; Magnetic Resonance Spectroscopy; Male; Seminal Vesicles; Sheep; Succinimides

1993
Comparison of peroxidase reaction mechanisms of prostaglandin H synthase-1 containing heme and mangano protoporphyrin IX.
    The Journal of biological chemistry, 1997, Apr-04, Volume: 272, Issue:14

    Topics: Animals; Aspirin; Cyclooxygenase Inhibitors; Heme; Hydrogen Peroxide; Indomethacin; Leukotrienes; Lipid Peroxides; Lipoxygenase Inhibitors; Male; Peroxidase; Photosensitizing Agents; Prostaglandin H2; Prostaglandin-Endoperoxide Synthases; Prostaglandins G; Prostaglandins H; Protoporphyrins; Sheep; Spectrophotometry, Atomic

1997
Liver haem metabolism in adjuvant-induced arthritic rats.
    Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:4

    Topics: 5-Aminolevulinate Synthetase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Bilirubin; Cytochrome P-450 Enzyme System; Cytochromes b5; Cytosol; Heme; Heme Oxygenase (Decyclizing); Indomethacin; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Porphyrins; Protein Biosynthesis; Rats; Rats, Wistar; Tryptophan Oxygenase

1996
Cyclooxygenase dependent release of heme from microsomal hemeproteins correlates with induction of heme oxygenase 1 transcription in human fibroblasts.
    Free radical biology & medicine, 1999, Volume: 26, Issue:5-6

    Topics: Butylated Hydroxytoluene; Cell Line; Cyclooxygenase Inhibitors; Fibroblasts; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hemeproteins; Humans; Hydrogen Peroxide; Indomethacin; Kinetics; Membrane Proteins; Microsomes; Oxidative Stress; Prostaglandin-Endoperoxide Synthases; Skin; Transcription, Genetic; Ultraviolet Rays

1999
Central CO-heme oxygenase pathway raises body temperature by a prostaglandin-independent way.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 88, Issue:5

    Topics: Animals; Body Temperature; Carbon Monoxide; Central Nervous System; Cyclooxygenase Inhibitors; Deuteroporphyrins; Dinoprostone; Enzyme Inhibitors; Fever; Heme; Heme Oxygenase (Decyclizing); Indomethacin; Injections, Intraperitoneal; Injections, Intraventricular; Lipopolysaccharides; Lysine; Male; Prostaglandins; Rats; Rats, Wistar; Time Factors

2000
Contributions of prostacyclin and nitric oxide to carbon monoxide-induced cerebrovascular dilation in piglets.
    American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:4

    Topics: Animals; Animals, Newborn; Arterioles; Carbon Monoxide; Heme; Indomethacin; Kinetics; Lysine; Microcirculation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Peptides; Pia Mater; Potassium Channels; Scorpion Venoms; Swine; Tetraethylammonium; Vasodilation; Vasodilator Agents

2001
Peroxidase self-inactivation in prostaglandin H synthase-1 pretreated with cyclooxygenase inhibitors or substituted with mangano protoporphyrin IX.
    The Journal of biological chemistry, 2001, Jun-08, Volume: 276, Issue:23

    Topics: Chromatography, High Pressure Liquid; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Flurbiprofen; Heme; Indomethacin; Isoenzymes; Kinetics; Peroxidases; Prostaglandin-Endoperoxide Synthases; Protein Conformation; Protoporphyrins; Spectrometry, Mass, Electrospray Ionization

2001
Role of prostaglandins in heme-induced fever.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 8

    Topics: Animals; Body Temperature; Brain; Dinoprostone; Dose-Response Relationship, Drug; Fever; Heme; Immunoglobulin G; Immunoglobulins; Indomethacin; Injections, Intraventricular; Lysine; Male; Rats; Rats, Sprague-Dawley

2006
Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer.
    The Journal of biological chemistry, 2013, Oct-04, Volume: 288, Issue:40

    Topics: Acetylation; Amino Acid Sequence; Amino Acid Substitution; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Flurbiprofen; Guanidine; Heme; Humans; Indomethacin; Kinetics; Models, Biological; Mutant Proteins; Mutation; Naproxen; Oxygen; Palmitic Acid; Peroxidase; Protein Multimerization; Pyrazoles; Substrate Specificity; Sulfonamides

2013
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