indomethacin has been researched along with clonidine in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (46.38) | 18.7374 |
| 1990's | 16 (23.19) | 18.2507 |
| 2000's | 12 (17.39) | 29.6817 |
| 2010's | 9 (13.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borrelli, AR; Gawlak, D; Gensmantel, NP; Loch, JT; Radov, LA; Toder, BH; Wu, ES | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dinnendahl, V; Gumulka, SW | 1 |
| Blake, DE; Holsapple, MP; Yim, GK | 1 |
| Knoll, J; Török, TL; Vizi, SE; Zséli, J | 1 |
| Block, HU; Förster, W; Taube, C | 1 |
| Agostoni, A; Brandi, G; Cottino, A; Gai, V; Gastaldi, L; Lisino, F; Nattero, G | 1 |
| Block, HU; Föster, W; Taube, C | 1 |
| Block, HU; Förster, W; Mest, HJ; Taube, C | 1 |
| Grimaud, N; Jugé, M; Petit, JY; Robert, B; Welin, L | 1 |
| Dinari, G; Kiro, A; Marcus, H; Zahavi, I | 1 |
| Blandford, DE; Smyth, DD | 1 |
| Reis, CC | 1 |
| Johnson, RD; Minneman, KP | 1 |
| Majewski, H; Murphy, TV | 1 |
| Allgaier, C; Hertting, G; Jäger, T | 1 |
| Fleeker, C; Rytting, JH; Wong, O | 1 |
| Hashimoto, H; Hasui, M; Igarashi, N; Kato, E; Minami, S; Okabe, T; Sato, T | 1 |
| DiJoseph, JF; Eash, JR; Mir, GN | 1 |
| Jayakody, RL; Kappagoda, CT; Senaratne, MP | 1 |
| Ben-Zvi, Z; Leibson, V | 1 |
| Magagna, A; Pedrinelli, R; Salvetti, A; Scapellato, L; Stornello, M | 1 |
| Bueno, L; Primi, MP | 1 |
| Karaki, H; Murakami, K; Urakawa, N | 1 |
| Kanaoka, R; Maeda-Hagiwara, M; Watanabe, H; Watanabe, K | 1 |
| Owman, C; Schmidt, G; Sjöberg, NO; Walles, B | 1 |
| Chinea, G; Oronsky, AL; Perper, RJ; Sanda, M | 1 |
| Beubler, E; Bukhave, K; Rask-Madsen, J | 1 |
| Cipriani, C; Divano, C; Guarrera, M; Parodi, A; Rebora, A | 1 |
| Boucher, R; Garcia, R; Genest, J; Gutkowska, J; Schiffrin, EL | 1 |
| Metz, SA; Robertson, RP | 1 |
| Holsapple, MP; Nichols, DE; Trizzino, J; Yim, GK | 1 |
| Clemmons, RM; Huston, LY; Meyers, KM | 1 |
| Kaplan, HR; Smith, RD; Tessman, DK | 1 |
| Hedler, L; Hertting, G; Reimann, W; Starke, K; Steinhauer, HB | 1 |
| Barrio, A; Gimeno, AL; Pardal, JF | 1 |
| Diamond, S; Medina, JL | 1 |
| Karppanen, H; Sirén, AL | 1 |
| Derksen, FJ; Robinson, NE; Wang, ZW; Yu, MF | 1 |
| Büyüktimkin, N; Büyüktimkin, S; Rytting, JH | 1 |
| Dinh-Xuan, AT; Higenbottam, TW; Kealey, T; Pepke-Zaba, J; Ridden, C | 1 |
| Blatteis, CM; Romanovsky, AA; Shido, O; Ungar, AL | 1 |
| Borycz, J; Bugajski, AJ; Bugajski, J; Gadek-Michalska, A; Głód, R | 1 |
| Borycz, J; Bugajski, J; Gadek-Michalska, A; Głód, R; Ołowska, A | 1 |
| D'Hondt, A; Depierreux, M; Hanson, B; Lustman, F | 1 |
| Darkwa, FK; Smyth, DD | 1 |
| Bert, L; Denoroy, L; Lambás-Señas, L; Renaud, B; Robert, F | 1 |
| Connolly, C; Docherty, JR; McCormick, PA | 1 |
| Arnold, JM; Callow, ID; Campisi, P; Feng, Q; Lambert, ML | 1 |
| Bugajski, J; Gadek-Michalska, A; Glód, R | 1 |
| Carvalho, LC; de Moura, RS; Madeira, SV; Miranda, DZ; Pinto, AC; Rangel, BM; Resende, AC; Rubenich, LM; Sicca, RF; Souza, MA; Tano, T | 1 |
| Bendhack, LM; Molin, JC | 1 |
| Man, RY; Ng, KF; Vanhoutte, PM; Wong, ES | 1 |
1 review(s) available for indomethacin and clonidine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for indomethacin and clonidine
| Article | Year |
|---|---|
[Therapeutic possibilities in idiopathic headaches. Analysis of 1000 cases (author's transl)].
Topics: Aspirin; Caffeine; Cinnarizine; Clinical Trials as Topic; Clonidine; Cyproheptadine; Drug Therapy, Combination; Ergotamine; Headache; Histamine; Humans; Indomethacin; Metergoline; Methysergide; Migraine Disorders; Pizotyline; Prochlorperazine; Reserpine; Retrospective Studies; Urea | 1975 |
67 other study(ies) available for indomethacin and clonidine
| Article | Year |
|---|---|
Flavones. 3. Synthesis, biological activities, and conformational analysis of isoflavone derivatives and related compounds.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Flavonoids; Male; Molecular Conformation; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Structure-Activity Relationship | 1992 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs | 2013 |
Stress-induced alterations of cyclic nucleotide levels in brain: effects of centrally acting drugs.
Topics: Aminooxyacetic Acid; Animals; Brain; Brain Chemistry; Chlorpromazine; Clonidine; Cyclic AMP; Cyclic GMP; Diazepam; Diphenhydramine; Haloperidol; Indomethacin; Male; Mice; Pentobarbital; Phentolamine; Propanolamines; Propranolol; Reserpine; Stress, Physiological | 1977 |
Reversible depression of electrically-induced contractions of guinea pig longitudinal muscle by a reversible inhibitor of prostaglandin synthetase.
Topics: Amidines; Animals; Chlorphenamidine; Clonidine; Cyclooxygenase Inhibitors; Guinea Pigs; Indomethacin; Lidocaine; Morphine; Muscle Contraction; Naloxone; Norepinephrine; Phentolamine; Prostaglandins E; Tolazoline | 1979 |
Effect of prostaglandin E1 and indomethacin on responses of longitudinal muscle of guinea-pig ileum to cholecystokinin.
Topics: Acetylcholine; Animals; Cecum; Cholecystokinin; Clonidine; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Membrane Potentials; Morphine; Muscle Contraction; Naloxone; Norepinephrine; Phentolamine; Prostaglandins E; Tetrodotoxin | 1979 |
[Abolition of the prostaglandin synthesis inhibiting effect of indomethacin by antihypertensives].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Clonidine; Dihydralazine; Indomethacin; Kidney; Methyldopa; Prostaglandins; Rabbits; Reserpine | 1979 |
[Effect of antihypertensive agents on the in vitro biosynthesis of prostaglandin E and F2 alpha in the rabbit kidney medulla].
Topics: Animals; Antihypertensive Agents; Clonidine; Dihydralazine; In Vitro Techniques; Indomethacin; Kidney; Kidney Medulla; Methyldopa; Norepinephrine; Prostaglandins E; Prostaglandins F; Rabbits; Reserpine; Stimulation, Chemical | 1975 |
[Acute prostaglandin E changes in the kidney medulla after intravenous application of blood pressure active drugs in rabbits].
Topics: Animals; Blood Pressure; Clonidine; Dihydralazine; Female; Heart Rate; Indomethacin; Kidney; Kidney Medulla; Male; Methyldopa; Norepinephrine; Prostaglandins E; Rabbits; Reserpine | 1975 |
Effect of clonidine on experimental brain edema in the rat.
Topics: Animals; Blood Pressure; Brain; Brain Edema; Clonidine; Copper; Dexamethasone; Indomethacin; Male; Phospholipases A; Phospholipases A2; Potassium; Rats; Rats, Wistar; Sodium; Yohimbine | 1992 |
L-dopa is protective against indomethacin-induced small intestinal ulceration in the rat: possible role of an alpha-2-adrenergic mechanism.
Topics: Animals; Clonidine; Haloperidol; Indomethacin; Intestinal Diseases; Intestinal Mucosa; Levodopa; Male; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Ulcer; Yohimbine | 1992 |
Potentiation of the natriuretic effect of clonidine following indomethacin in the rat.
Topics: Animals; Clonidine; Dinoprostone; Drug Synergism; Indomethacin; Male; Natriuresis; Potassium; Rats; Rats, Inbred Strains; Sodium | 1991 |
Study of the contraction induced by norepinephrine and clonidine in the isolated guinea-pig ileum.
Topics: Animals; Atropine; Clonidine; Guinea Pigs; Ileum; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Practolol; Prazosin; Yohimbine | 1991 |
Differentiation of alpha 1-adrenergic receptors linked to phosphatidylinositol turnover and cyclic AMP accumulation in rat brain.
Topics: 1-Methyl-3-isobutylxanthine; Alkylating Agents; Animals; Aspirin; Brain; Brain Mapping; Calcium; Clonidine; Cyclic AMP; In Vitro Techniques; Indomethacin; Phenethylamines; Phosphatidylinositols; Rats; Receptors, Adrenergic, alpha; Tetradecanoylphorbol Acetate; Tetralones | 1987 |
Modulation of noradrenaline release in slices of rat kidney cortex through alpha 1- and alpha 2-adrenoceptors.
Topics: Animals; Clonidine; Dioxanes; Idazoxan; In Vitro Techniques; Indomethacin; Kidney Cortex; Male; Methoxamine; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Renal Circulation; Theophylline | 1989 |
Endogenous noradrenaline impairs the prostaglandin-induced inhibition of noradrenaline release.
Topics: Animals; Cerebral Cortex; Clonidine; Dinoprostone; Electric Stimulation; Female; In Vitro Techniques; Indomethacin; Male; Norepinephrine; Prostaglandin Antagonists; Rats; Rats, Inbred Strains; Yohimbine | 1989 |
Facilitated transport of basic and acidic drugs in solutions through snakeskin by a new enhancer--dodecyl N,N-dimethylamino acetate.
Topics: Animals; Chromatography, High Pressure Liquid; Clonidine; Excipients; Glycine; Hydrogen-Ion Concentration; In Vitro Techniques; Indicators and Reagents; Indomethacin; Skin Absorption; Snakes | 1989 |
Recurrent attacks of vomiting, hypertension and psychotic depression: a syndrome of periodic catecholamine and prostaglandin discharge.
Topics: Adolescent; Adrenocorticotropic Hormone; Arginine Vasopressin; Child, Preschool; Clonidine; Dinoprostone; Dopamine; Epinephrine; Female; Humans; Hypertension; Indomethacin; Levodopa; Metoclopramide; Norepinephrine; Periodicity; Prostaglandins E; Psychotic Disorders; Recurrence; Syndrome; Vomiting | 1988 |
Gastric antisecretory and antiulcer effects of WHR1582A, a compound exerting alpha-2 adrenoceptor agonist activity.
Topics: Adrenergic alpha-Agonists; Animals; Anti-Ulcer Agents; Aspirin; Carbachol; Clonidine; Cysteamine; Dimaprit; Gastric Acid; Gastric Mucosa; Indomethacin; Ligation; Male; Muscle Contraction; Norepinephrine; Phenylurea Compounds; Rats; Rats, Inbred Strains; Reserpine; Stomach Ulcer; Stress, Physiological; Thiourea; Yohimbine | 1987 |
Potentiation of the responses to transmural nerve stimulation by alpha-agonists: a possible role in vivo.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Dogs; Electric Stimulation; Epinephrine; Indomethacin; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Propranolol; Saphenous Vein | 1987 |
Antiulcer activity of clonidine: lack of effect on gastric prostaglandins.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Clonidine; Dinoprostone; Female; Gastric Mucosa; Indomethacin; Prostaglandins E; Rats; Stomach Ulcer; Yohimbine | 1987 |
Calcium antagonists: interactions in hypertension.
Topics: Adult; Blood Pressure; Clonidine; Drug Interactions; Female; Humans; Hypertension; Indomethacin; Male; Middle Aged; Nifedipine; Renin | 1986 |
Effects of centrally administered naloxone on gastrointestinal myoelectrical activity in morphine-dependent rats.
Topics: Animals; Atropine; Clonidine; Digestive System; Electrophysiology; Enkephalin, Leucine; Gastrointestinal Motility; Indomethacin; Injections, Intraventricular; Injections, Subcutaneous; Male; Methysergide; Morphine; Naloxone; Phentolamine; Rats; Substance-Related Disorders; Tolazoline | 1987 |
Role of endothelium in the contractions induced by norepinephrine and clonidine in rat aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Clonidine; Endothelium; In Vitro Techniques; Indomethacin; Male; Methylene Blue; Muscle Contraction; Muscle, Smooth, Vascular; Nitric Oxide; Norepinephrine; Potassium; Prazosin; Quinacrine; Rats; Rats, Inbred Strains; Tetraethylammonium Compounds; Vasodilator Agents; Yohimbine | 1985 |
Influence of clonidine and a new related imidazoline derivative (tizanidine) on rat gastric mucosa.
Topics: Animals; Clonidine; Gastric Acid; Gastric Mucosa; Glycoproteins; Indomethacin; Male; Muscle Relaxants, Central; Rats; Rats, Inbred Strains | 1986 |
Influence of adrenoreceptor agonists and antagonists on ovulation in the rabbit ovary perfused in vitro.
Topics: Animals; Chorionic Gonadotropin; Clonidine; Female; In Vitro Techniques; Indomethacin; Norepinephrine; Ovarian Follicle; Ovary; Ovulation; Perfusion; Phenoxybenzamine; Phentolamine; Rabbits; Sympatholytics; Sympathomimetics; Terbutaline | 1985 |
Leukocyte chemotaxis in vivo. II. Analysis of the selective inhibition of neutrophil or mononuclear cell accumulation.
Topics: Animals; Bucladesine; Carrageenan; Chemotaxis; Chloroquine; Chlorpromazine; Chromium Radioisotopes; Clonidine; Colchicine; Cyclophosphamide; Female; Flufenamic Acid; Indomethacin; Inflammation; Leukocyte Transfusion; Leukocytes; Methylprednisolone; Monocytes; Neutrophils; Phenylbutazone; Rats; Transplantation, Homologous; Venoms; Vinblastine | 1974 |
Colonic secretion mediated by prostaglandin E2 and 5-hydroxytryptamine may contribute to diarrhea due to morphine withdrawal in the rat.
Topics: Animals; Atropine; Clonidine; Colon; Cyclic AMP; Diarrhea; Dinoprostone; Female; Humans; Indomethacin; Ketanserin; Morphine Dependence; Naloxone; Piperidines; Prostaglandins E; Rats; Rats, Inbred Strains; Serotonin; Substance Withdrawal Syndrome | 1984 |
Flushing in rosacea: a possible mechanism.
Topics: Adult; Aspirin; Body Temperature; Bradykinin; Clonidine; Epinephrine; Face; Female; Humans; Indomethacin; Male; Methysergide; Middle Aged; Rosacea; Skin Temperature | 1982 |
Role of prostaglandins, beta-adrenoceptors, and the central nervous system in the control of renin release in conscious sodium-depleted rats.
Topics: Animals; Central Nervous System; Clonidine; Drug Therapy, Combination; Hyponatremia; Indomethacin; Kidney; Male; Propranolol; Prostaglandins; Rats; Receptors, Adrenergic; Receptors, Adrenergic, beta; Renin | 1980 |
Prostaglandin synthesis inhibitors reverse alpha-adrenergic inhibition of acute insulin response to glucose.
Topics: Adult; Blood Glucose; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Humans; Indomethacin; Insulin; Male; Middle Aged; Prostaglandins E; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Sodium Salicylate | 1980 |
Therapeutic and adjunctive applications of an imidazoline anti-inflammatory agent.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Aspirin; Carrageenan; Clonidine; Drug Therapy, Combination; Edema; Indomethacin; Male; Rats; Rats, Inbred Strains; Stomach Ulcer | 1983 |
Regulation of canine platelet function II. Catecholamines.
Topics: Adenosine Diphosphate; Animals; Arachidonic Acids; Blood Platelets; Clonidine; Dobutamine; Dogs; Drug Synergism; Epinephrine; Female; Indomethacin; Isoproterenol; Kinetics; Male; Phenylephrine; Platelet Aggregation | 1983 |
Acute tolerance to prazosin in conscious hypertensive rats: involvement of the renin-angiotensin system.
Topics: Angiotensin II; Animals; Captopril; Cardiovascular Agents; Clonidine; Dose-Response Relationship, Drug; Drug Tolerance; Hydrochlorothiazide; Hypertension; Indomethacin; Male; Methyltyrosines; Prazosin; Propranolol; Quinazolines; Rats; Renin | 1981 |
Effect of prostaglandins D2, E2 and F2alpha on catecholamine release from slices of rat and rabbit brain.
Topics: Animals; Brain; Catecholamines; Clonidine; Female; In Vitro Techniques; Indomethacin; Male; Phentolamine; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Rabbits; Rats; Species Specificity; Tritium | 1981 |
Inhibitors of prostaglandins synthesis and the release of noradrenaline evoked by black widow spider venom gland extract in peripheral catecholamine neurons.
Topics: Animals; Arthropod Venoms; Aspirin; Black Widow Spider; Catecholamines; Clonidine; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Neurons; Norepinephrine; Potassium; Prostaglandins; Rats; Spider Venoms; Sympathetic Nervous System | 1980 |
Newer drug therapies for headache.
Topics: Antidepressive Agents; Aspirin; Bromocriptine; Clonidine; Cluster Headache; Dipyridamole; Headache; Humans; Indomethacin; Lithium; Migraine Disorders; Pizotyline; Prednisone; Propranolol | 1980 |
Influence of analgesic antipyretics on the central cardiovascular effects of clonidine in rats.
Topics: Acetaminophen; Animals; Blood Pressure; Clonidine; Dose-Response Relationship, Drug; Female; Heart Rate; Indomethacin; Injections, Intraventricular; Meclofenamic Acid; Prostaglandins F; Rats | 1980 |
Acetylcholine release from airway cholinergic nerves in horses with heaves, an airway obstructive disease.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Cholinergic Fibers; Chromatography, High Pressure Liquid; Clonidine; Dinoprostone; Electric Stimulation; Female; Horse Diseases; Horses; Indomethacin; Lung Diseases, Obstructive; Male; Muscle, Smooth; Parasympathetic Nervous System; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Stimulation, Chemical; Trachea | 1995 |
Synthesis and enhancing effect of dodecyl 2-(N,N-dimethylamino)propionate on the transepidermal delivery of indomethacin, clonidine, and hydrocortisone.
Topics: Administration, Cutaneous; Alanine; Animals; Biodegradation, Environmental; Clonidine; Colubridae; Hydrocortisone; In Vitro Techniques; Indomethacin; Skin Absorption | 1993 |
Alpha-adrenoceptor stimulation of porcine pulmonary arteries.
Topics: Acetylcholine; Animals; Clonidine; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Methoxamine; Phenylephrine; Pulmonary Artery; Radioimmunoassay; Receptors, Adrenergic, alpha; Swine; Vasoconstriction | 1993 |
Genesis of biphasic thermal response to intrapreoptically microinjected clonidine.
Topics: Animals; Body Temperature; Clonidine; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Male; Microinjections; Preoptic Area; Prostaglandin-Endoperoxide Synthases; Stereotaxic Techniques; Yohimbine | 1993 |
Effect of indomethacin on the pituitary-adrenocortical response to adrenergic stimulation.
Topics: Adrenal Cortex; Adrenergic Agents; Animals; Clonidine; Corticosterone; Cyclooxygenase Inhibitors; Epinephrine; Indomethacin; Isoproterenol; Male; Norepinephrine; Phenylephrine; Pituitary Gland; Rats; Rats, Wistar | 1996 |
The role of prostaglandins and the hypothalamic and hippocampal histamine in the clonidine-induced pituitary-adrenocortical response.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Corticosterone; Hippocampus; Histamine; Hypothalamus; Indomethacin; Male; Pituitary-Adrenal System; Prostaglandins; Rats; Rats, Wistar | 1996 |
Nephrotic syndrome after norfloxacin.
Topics: Aged; Amlodipine; Anti-Infective Agents; Antihypertensive Agents; Clonidine; Creatinine; Diuretics; Female; Furosemide; Humans; Indomethacin; Isosorbide Dinitrate; Lisinopril; Nephrotic Syndrome; Norfloxacin; Proteinuria; Urinary Tract Infections | 1996 |
Inhibition of the natriuretic action of the imidazoline receptor agonist moxonidine by indometacin in the rat.
Topics: Adrenergic alpha-Agonists; Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Creatinine; Cyclooxygenase Inhibitors; Dinoprostone; Drug Interactions; Imidazoles; Imidazoline Receptors; Indomethacin; Kidney; Male; Natriuresis; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Drug | 1995 |
In vivo monitoring of extracellular noradrenaline and glutamate from rat brain cortex with 2-min microdialysis sampling using capillary electrophoresis with laser-induced fluorescence detection.
Topics: Animals; Aspartic Acid; Clonidine; Electrophoresis, Capillary; Evaluation Studies as Topic; Extracellular Space; Fluorescent Dyes; Glutamic Acid; Indomethacin; Lasers; Male; Microdialysis; Microelectrodes; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sympatholytics | 1996 |
Effects of the selective cyclooxygenase-2 inhibitor nimesulide on vascular contractions in endothelium-denuded rat aorta.
Topics: Animals; Aorta; Bridged Bicyclo Compounds, Heterocyclic; Clonidine; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Endothelin-1; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Indomethacin; Isoenzymes; Male; Muscle Contraction; Nifedipine; Phenylephrine; Potassium Chloride; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Sulfonamides | 1998 |
Enhanced in vivo alpha1- and alpha2-adrenoceptor-mediated venoconstriction with indomethacin in humans.
Topics: Adrenergic alpha-Agonists; Adult; Clonidine; Dinoprost; Dose-Response Relationship, Drug; Female; Humans; Indomethacin; Male; Phenylephrine; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Vasoconstriction | 1998 |
The influence of indomethacin on the acth secretion induced by central stimulation of adrenergic receptors.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenocorticotropic Hormone; Animals; Brain; Clenbuterol; Clonidine; Cyclooxygenase Inhibitors; Indomethacin; Injections, Intraperitoneal; Injections, Intraventricular; Isoproterenol; Male; Phenylephrine; Rats; Rats, Wistar | 2000 |
Mechanism of the endothelium-dependent vasodilation and the antihypertensive effect of Brazilian red wine.
Topics: Acetylcholine; Administration, Oral; Alcohol Drinking; Animals; Apamin; Atropine; Blood Pressure; Bradykinin; Brazil; Charybdotoxin; Clonidine; Deoxycholic Acid; Drug Therapy, Combination; Endothelium, Vascular; Flavonoids; Glyburide; Guanylate Cyclase; Hypertension; Indomethacin; Male; Mesenteric Arteries; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitroglycerin; Norepinephrine; Oxadiazoles; Perfusion; Phenols; Polyphenols; Potassium Chloride; Pressure; Pyrilamine; Quinazolines; Quinoxalines; Rats; Rats, Wistar; Vasoconstriction; Vasodilation; Wine; Yohimbine | 2004 |
Clonidine induces rat aorta relaxation by nitric oxide-dependent and -independent mechanisms.
Topics: Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Clonidine; Dinoprost; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Indomethacin; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ouabain; Phenylephrine; Potassium Chloride; Prazosin; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Vasodilation | 2004 |
Dexmedetomidine induces both relaxations and contractions, via different {alpha}2-adrenoceptor subtypes, in the isolated mesenteric artery and aorta of the rat.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Animals; Aorta; Brimonidine Tartrate; Clonidine; Dexmedetomidine; Endothelium, Vascular; In Vitro Techniques; Indomethacin; Male; Mesenteric Arteries; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Naphthalenes; NG-Nitroarginine Methyl Ester; Pertussis Toxin; Prazosin; Propionates; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Thromboxane | 2010 |