Compounds > indoleacetic acid

indoleacetic acid and indican

indoleacetic acid has been researched along with indican in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199011 (22.00)18.7374
1990's0 (0.00)18.2507
2000's4 (8.00)29.6817
2010's26 (52.00)24.3611
2020's9 (18.00)2.80

Authors

AuthorsStudies
Mabuchi, H; Nakahashi, H3
Barnett, AL; Veening, H1
Goto, S; Ikeda, K; Kimura, T; Nakayama, T; Yoshitomi, H1
Hosokawa, A; Motojima, M; Muraki, T; Yamato, H; Yoshioka, T1
DOLCINI, HA; DONALDSON, RM; GRAY, SJ1
REDDY, V; SRIKANTIA, SG; VENKATACHALAM, PS1
BENSON, GD; HAEFFNER, LJ; KOWLESSAR, OD1
BESSMAN, SP1
FORDTRAN, JS; POLTER, DE; SCROGGIE, WB1
ANDERSON, JA; DOEDEN, D; DRUMMOND, KN; GOOD, RA; MICHAEL, AF1
Deguchi, T; Kouno, Y; Otagiri, M; Takadate, A; Terasaki, T1
Hanada, K; Ichihara, S; Kikkawa, A; Ogata, H; Ogawa, R; Sasaki, Y; Son, K1
Davilas, A; Koupparis, M; Macheras, P; Valsami, G1
Argilés, A; Bergé-Lefranc, D; Brunet, P; Calaf, R; Cerini, C; Charpiot, P; Dignat-George, F; Dou, L; Génovésio, C; Gondouin, B; Jourde-Chiche, N; Morange, S; Rathelot, P; Verhaeghe, P1
Balcells, M; Bosch, I; Chitalia, VC; Edelman, ER; Kolandaivelu, K; Martorell, J; Shivanna, S1
Boelaert, J; Eloot, S; Glorieux, G; Lynen, F; Sandra, P; Van Landschoot, M; Vanholder, R; Waterloos, MA1
Arnaud, L; Brunet, P; Burtey, S; Calaf, R; Cerini, C; Dignat-George, F; Dou, L; Duval-Sabatier, A; Gondouin, B; Jourde-Chiche, N; Lacroix, R; Pletinck, A; Poitevin, S; Sallée, M; Vanholder, R1
Furukubo, T; Hiraoka, S; Hosoda, S; Izumi, S; Minegaki, T; Miyoshi, A; Nagano, Y; Nishiguchi, K; Shiraishi, A; Tsujimoto, M; Yamakawa, T1
Fujioka, T; Itoh, H; Kawasaki, K; Kishino, S; Mimata, H; Ohno, K; Sato, F; Sato, Y; Suzuki, Y1
Dhondt, A; Eloot, S; Glorieux, G; Neirynck, N; Van Biesen, W; Vanholder, R1
Bi, K; Chen, X; Gu, L; Jiang, Y; Lu, H; Wang, X; Zhang, Y1
Furukubo, T; Izumi, S; Minegaki, T; Nishiguchi, K; Oda, T; Ogino, H; Shinmoto, T; Tachiki, H; Tsujimoto, M; Uchiyama, H; Yamakawa, T; Yoshida, T1
Ichimura, Y; Ideuchi, H; Oda, M; Saitoh, H; Takamatsu, H; Takeda, K2
Deltombe, O; Dhondt, A; Eloot, S; Glorieux, G; Massy, Z; Van Biesen, W1
Cui, D; Dong, W; Gao, C; Ji, S; Qi, Y; Shi, J; Song, W1
Hoffmann, M; Liu, H; Narayanan, R; Surapaneni, S1
Liabeuf, S; Massy, ZA; Villain, C1
Davies, N; Hilder, EF; Jose, MD; Karu, N; McKercher, C; Nichols, DS; Shellie, RA1
Behr, C; Fabian, E; Kamp, H; Krennrich, G; Mellert, W; Peter, E; Rietjens, IMCM; Strauss, V; van Ravenzwaay, B; Walk, T1
Borges, NA; Brito, JS; Esgalhado, M; Mafra, D; Magliano, DC; Soulage, CO1
de Loor, H; Deltombe, O; Dhondt, A; Eloot, S; Glorieux, G; Meijers, B; Van Biesen, W1
Ei, I; Gejyo, F; Goto, S; Iguchi, A; Kaneko, Y; Kazama, JJ; Narita, I; Omori, K; Sato, M; Sato, Y; Suzuki, Y; Takahashi, Y; Wakamatsu, T; Yamamoto, S1
Bataille, S; Berland, Y; Brunet, P; Burtey, S; Duval, A; Gentile, S; McKay, N; Mouelhi, Y; Pelletier, M; Sallée, M1
Anjos, JS; Black, AP; Cardozo, L; Carmo, FL; Carraro Eduardo, JC; de Carvalho Ferreira, D; Dolenga, CJ; Mafra, D; Nakao, LS; Rosado, A1
Chinnappa, S; Glorieux, G; Mooney, A; Tu, YK; Vanholder, R; Yeh, YC1
da Silva, BP; de Castro Moreira, ME; Hermsdorff, HH; Lopes, RCSO; Mantovani, HC; Martino, HSD; Queiroz, VAV; Theodoro, JMV1
Bennis, Y; Bodeau, S; Choukroun, G; Cluet, Y; Combe, C; Dussol, B; El Esper, N; Fouque, D; Liabeuf, S; Titeca-Beauport, D; Ureña, P1
Deltombe, O; Eloot, S; Glorieux, G; Marzouki, S; Masereeuw, R; Schneditz, D1
Glorieux, G; Meireles, T; Nakao, LS; Pecoits-Filho, R; Rodrigues, SD; Romero, N; Santos, SS; Zhang, DD1
Hillmer, H; Krause, S; Marcelli, D; Meibaum, J; Strohhöfer, C1
Adoberg, A; Arduan Ortiz, A; Arund, J; Dhondt, A; Fernström, A; Fridolin, I; Glorieux, G; Gonzalez-Parra, E; Leis, L; Luman, M; Paats, J; Perez-Gomez, VM; Pilt, K; Sanchez-Ospina, D; Segelmark, M; Uhlin, F1
Glorieux, G; Gryp, T; Huys, GRB; Joossens, M; Van Biesen, W; Vaneechoutte, M1
Burtey, S; Corbeau, P; Cristol, JP; Dunyach-Remy, C; Lavigne, JP; Moranne, O; Olivier, V; Sutra, T1
Alvarenga, L; Cardozo, LFMF; de S G Moreira, L; Fouque, D; Lima, JD; Mafra, D; Nakao, LS; Rodrigues, SD; Salarolli, RT; Teixeira, KTR1
Domon, M; Goto, S; Goto, Y; Ito, T; Narita, I; Sasahara, K; Yamaguchi, K; Yamamoto, S1
Maruyama, T; Nishi, K; Otagiri, M; Sakurama, K; Watanabe, H; Yamasaki, K1
Burtey, S; Cerini, C; McKay, N; Poitevin, S; Vial, R1

Reviews

2 review(s) available for indoleacetic acid and indican

ArticleYear
Protein-bound toxins: has the Cinderella of uraemic toxins turned into a princess?
    Clinical science (London, England : 1979), 2016, 12-01, Volume: 130, Issue:23

    Topics: Animals; Cardiovascular Diseases; Cresols; Humans; Indican; Indoleacetic Acids; Proteins; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Uremia

2016
Aryl Hydrocarbon Receptor Activation in Chronic Kidney Disease: Role of Uremic Toxins.
    Nephron, 2017, Volume: 137, Issue:1

    Topics: Animals; Cardiovascular Diseases; Glucuronates; Humans; Indican; Indoleacetic Acids; Indoles; Models, Biological; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Toxins, Biological; Tryptophan; Uremia

2017

Trials

4 trial(s) available for indoleacetic acid and indican

ArticleYear
Adsorption of Protein-Bound Uremic Toxins Through Direct Hemoperfusion With Hexadecyl-Immobilized Cellulose Beads in Patients Undergoing Hemodialysis.
    Artificial organs, 2018, Volume: 42, Issue:1

    Topics: Adsorption; Aged; Blood Proteins; Cellulose; Cresols; Feasibility Studies; Female; Hemoperfusion; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Male; Middle Aged; Porosity; Protein Binding; Renal Dialysis; Serum Albumin; Sulfuric Acid Esters; Toxins, Biological; Uremia

2018
Synbiotic meal decreases uremic toxins in hemodialysis individuals: A placebo-controlled trial.
    Food research international (Ottawa, Ont.), 2019, Volume: 116

    Topics: Aged; Bifidobacterium longum; Biomarkers; Brazil; Cresols; Female; Gastrointestinal Microbiome; Humans; Hydrogen-Ion Concentration; Indican; Indoleacetic Acids; Male; Meals; Middle Aged; Probiotics; Renal Dialysis; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Synbiotics; Urea; Uremia

2019
The Effect of Sevelamer on Serum Levels of Gut-Derived Uremic Toxins: Results from In Vitro Experiments and A Multicenter, Double-Blind, Placebo-Controlled, Randomized Clinical Trial.
    Toxins, 2019, 05-17, Volume: 11, Issue:5

    Topics: Adsorption; Aged; Chelating Agents; Cresols; Double-Blind Method; Female; Gastrointestinal Tract; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Renal Insufficiency, Chronic; Sevelamer; Sulfuric Acid Esters; Toxins, Biological; Uremia

2019
Can curcumin supplementation reduce plasma levels of gut-derived uremic toxins in hemodialysis patients? A pilot randomized, double-blind, controlled study.
    International urology and nephrology, 2021, Volume: 53, Issue:6

    Topics: Adult; Aged; Cresols; Curcumin; Dietary Supplements; Double-Blind Method; Female; Gastrointestinal Microbiome; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Pilot Projects; Renal Dialysis; Sulfuric Acid Esters; Toxins, Biological; Uremia

2021

Other Studies

44 other study(ies) available for indoleacetic acid and indican

ArticleYear
Profiling of endogenous ligand solutes that bind to serum proteins in sera of patients with uremia.
    Nephron, 1986, Volume: 43, Issue:2

    Topics: Blood Proteins; Chromatography, High Pressure Liquid; Hippurates; Hot Temperature; Humans; Indican; Indoleacetic Acids; Ligands; Protein Binding; Ultrafiltration; Uremia

1986
Inhibition of hepatic glutathione S-transferases by a major endogenous ligand substance present in uremic serum.
    Nephron, 1988, Volume: 49, Issue:4

    Topics: Animals; Cattle; Dinitrochlorobenzene; Furans; Glutathione Transferase; Humans; Indican; Indoleacetic Acids; Liver; Propionates; Protein Binding; Rats; Serum Albumin; Uremia

1988
Displacement by anionic drugs of endogenous ligands bound to albumin in uremic serum.
    Therapeutic drug monitoring, 1988, Volume: 10, Issue:3

    Topics: Binding Sites; Furans; Hippurates; Humans; Indican; Indoleacetic Acids; Propionates; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Uremia; Warfarin

1988
Liquid-chromatographic study of fluorescent compounds in hemodialysate solutions.
    Clinical chemistry, 1985, Volume: 31, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Indican; Indoleacetic Acids; Renal Dialysis; Solutions; Spectrometry, Fluorescence; Tryptophan; Tryptophanase; Uremia

1985
Plasma protein binding of frusemide in renal failure rabbits: investigation of endogenous protein binding inhibitors.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:10

    Topics: Acute Kidney Injury; Animals; Blood Proteins; Chromatography, Gel; Chromatography, High Pressure Liquid; Furosemide; Indican; Indoleacetic Acids; Indoles; Male; Mercuric Chloride; Molecular Weight; Protein Binding; Rabbits; Serum Albumin, Bovine

1984
Uremic toxins of organic anions up-regulate PAI-1 expression by induction of NF-kappaB and free radical in proximal tubular cells.
    Kidney international, 2003, Volume: 63, Issue:5

    Topics: Anions; Cells, Cultured; Free Radicals; Gene Expression; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Kidney Tubules, Proximal; NF-kappa B; Oxidative Stress; Plasminogen Activator Inhibitor 1; Promoter Regions, Genetic; Signal Transduction; Toxins, Biological; Up-Regulation; Uremia

2003
Urinary excretion of indolic compounds in rats with intestinal pouches.
    The American journal of physiology, 1961, Volume: 200

    Topics: Animals; Body Fluids; Indican; Indoleacetic Acids; Intestines; Rats

1961
CLINICAL AND BIOCHEMICAL FEATURES OF A CASE OF HARTNUP DISEASE.
    British medical journal, 1964, Feb-01, Volume: 1, Issue:5378

    Topics: Biochemical Phenomena; Biochemistry; Child; Genetics, Medical; Hartnup Disease; Humans; Indican; Indoleacetic Acids; Kidney; Kidney Diseases; Pellagra; Renal Aminoacidurias; Tryptophan; Urine

1964
ABNORMAL TRYPTOPHAN METABOLISM IN PATIENTS WITH ADULT CELIAC DISEASE, WITH EVIDENCE FOR DEFICIENCY OF VITAMIN B6.
    The Journal of clinical investigation, 1964, Volume: 43

    Topics: Adult; Biochemical Phenomena; Biochemistry; Celiac Disease; Dietary Proteins; Glutens; Humans; Hydroxyindoleacetic Acid; Indican; Indoleacetic Acids; Kynurenic Acid; Kynurenine; Proteins; Tetracycline; Tryptophan; Urine; Vitamin B 6; Vitamin B 6 Deficiency; Xanthurenates

1964
SOME BIOCHEMICAL LESSONS TO BE LEARNED FROM PHENYLKETONURIA.
    The Journal of pediatrics, 1964, Volume: 64

    Topics: Glutamates; Humans; Indican; Indoleacetic Acids; Indoles; Learning; Metabolism; Phenylacetates; Phenylalanine; Phenylketonurias; Pterins; Serotonin; Tryptophan; Tyrosine

1964
COLONIC ABSORPTION OF TRYPTOPHAN METABOLITES IN MAN.
    The Journal of laboratory and clinical medicine, 1964, Volume: 64

    Topics: Amino Acids; Caseins; Celiac Disease; Colon; Humans; Indican; Indoleacetic Acids; Intestinal Absorption; Intestine, Small; Intestines; Male; Physiology; Serotonin; Sprue, Tropical; Tryptophan; Urine

1964
TRYPTOPHAN METABOLISM IN MAN.
    The Journal of clinical investigation, 1964, Volume: 43

    Topics: Amino Acid Metabolism, Inborn Errors; Calcium; Child; Glucuronates; Humans; Indican; Indoleacetic Acids; Intestinal Absorption; Kynurenine; Male; Metabolism; ortho-Aminobenzoates; p-Aminohippuric Acid; Pyridines; Tryptophan; Urine; Xanthurenates

1964
Differential contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in vivo renal uptake of uremic toxins in rats.
    Pharmaceutical research, 2005, Volume: 22, Issue:4

    Topics: Animals; Biological Transport; Carbon Radioisotopes; Estrone; Furans; Hippurates; Indican; Indoleacetic Acids; Kidney; Male; Metabolic Clearance Rate; Organic Anion Transport Protein 1; Organic Cation Transport Proteins; p-Aminohippuric Acid; Penicillin G; Propionates; Rats; Rats, Wistar; Serum; Tritium

2005
Effects of indoxylsulfate on the in vitro hepatic metabolism of various compounds using human liver microsomes and hepatocytes.
    Nephron. Physiology, 2006, Volume: 103, Issue:4

    Topics: Biomarkers; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Hepatocytes; Humans; Indican; Indoleacetic Acids; Microsomes, Liver; Nicardipine

2006
In-vitro study on the competitive binding of diflunisal and uraemic toxins to serum albumin and human plasma using a potentiometric ion-probe technique.
    The Journal of pharmacy and pharmacology, 2006, Volume: 58, Issue:11

    Topics: Algorithms; Animals; Binding, Competitive; Blood Proteins; Calibration; Diflunisal; Hippurates; Humans; Indican; Indoleacetic Acids; Ion-Selective Electrodes; Potentiometry; Serum Albumin; Serum Albumin, Bovine; Technology, Pharmaceutical; Toxins, Biological; Uremia

2006
Determination of uremic solutes in biological fluids of chronic kidney disease patients by HPLC assay.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Aug-01, Volume: 879, Issue:23

    Topics: Aged; Chromatography, High Pressure Liquid; Cresols; Female; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Male; Middle Aged; Phenol; Phenols; Sulfuric Acid Esters; Uremia

2011
Uremic serum and solutes increase post-vascular interventional thrombotic risk through altered stability of smooth muscle cell tissue factor.
    Circulation, 2013, Jan-22, Volume: 127, Issue:3

    Topics: Adult; Aged; Cell Line; Coronary Vessels; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Male; Middle Aged; Myocytes, Smooth Muscle; Renal Dialysis; Risk Factors; Serum; Stents; Thromboplastin; Thrombosis; Ubiquitination; Uremia

2013
A novel UPLC-MS-MS method for simultaneous determination of seven uremic retention toxins with cardiovascular relevance in chronic kidney disease patients.
    Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:6

    Topics: Cardiovascular Diseases; Case-Control Studies; Chromatography, High Pressure Liquid; Cresols; Female; Furans; Glucuronides; Hippurates; Humans; Indican; Indoleacetic Acids; Male; Propionates; Renal Insufficiency, Chronic; Severity of Illness Index; Sulfuric Acid Esters; Tandem Mass Spectrometry; Uremia; Uric Acid

2013
Indolic uremic solutes increase tissue factor production in endothelial cells by the aryl hydrocarbon receptor pathway.
    Kidney international, 2013, Volume: 84, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Benzoquinones; Case-Control Studies; Cells, Cultured; Dioxins; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Indican; Indoleacetic Acids; Lactams, Macrocyclic; Leukocytes, Mononuclear; Male; Middle Aged; Polymerase Chain Reaction; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; RNA, Small Interfering; Signal Transduction; Thromboplastin; Tissue Array Analysis; Umbilical Veins; Up-Regulation

2013
Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease.
    Toxins, 2013, Aug-19, Volume: 5, Issue:8

    Topics: Cell Line, Tumor; Cytochrome P-450 CYP3A; Erythromycin; Furans; Hippurates; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Liver; Microsomes, Liver; Pregnane X Receptor; Propionates; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger; Steroid Hydroxylases; Toxins, Biological; Vitamin D; Vitamin D3 24-Hydroxylase

2013
Association of plasma concentration of 4β-hydroxycholesterol with CYP3A5 polymorphism and plasma concentration of indoxyl sulfate in stable kidney transplant recipients.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Aged; Alleles; Asian People; Biomarkers; Cytochrome P-450 CYP3A; Female; Genotype; Humans; Hydroxycholesterols; Indican; Indoleacetic Acids; Kidney; Kidney Transplantation; Male; Middle Aged; Polymorphism, Genetic; Young Adult

2014
Does the adequacy parameter Kt/V(urea) reflect uremic toxin concentrations in hemodialysis patients?
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Aged; Aged, 80 and over; beta 2-Microglobulin; Biomarkers; Creatinine; Cresols; Diabetes Mellitus; Female; Furans; Glucuronides; Hippurates; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Multivariate Analysis; Propionates; Renal Dialysis; Sulfuric Acid Esters; Treatment Outcome; Urea; Uremia; Uric Acid

2013
Determination of 12 potential nephrotoxicity biomarkers in rat serum and urine by liquid chromatography with mass spectrometry and its application to renal failure induced by Semen Strychni.
    Journal of separation science, 2014, Volume: 37, Issue:9-10

    Topics: Animals; Biomarkers; Chromatography, Liquid; Citric Acid; Creatinine; Drugs, Chinese Herbal; Glycine; Guanidines; Hippurates; Indican; Indoleacetic Acids; Kynurenic Acid; Male; Mass Spectrometry; Medicine, Chinese Traditional; Molecular Structure; Plant Extracts; Rats; Rats, Sprague-Dawley; Renal Insufficiency; Succinates; Taurine; Uric Acid; Xanthurenates

2014
Uremic toxins enhance statin-induced cytotoxicity in differentiated human rhabdomyosarcoma cells.
    Toxins, 2014, Sep-03, Volume: 6, Issue:9

    Topics: Apoptosis; Cell Differentiation; Cell Line, Tumor; Cell Survival; Drug Synergism; Furans; Hippurates; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indican; Indoleacetic Acids; Pravastatin; Propionates; Rhabdomyosarcoma; Simvastatin; Toxins, Biological; Uremia

2014
[Plasma concentrations of anionic uremic toxins in hemodialysis patients and their effects on protein binding of pravastatin].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2015, Volume: 135, Issue:6

    Topics: Aged; Aged, 80 and over; Female; Furans; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Pravastatin; Propionates; Protein Binding; Renal Dialysis; Serum Albumin

2015
Exploring Protein Binding of Uremic Toxins in Patients with Different Stages of Chronic Kidney Disease and during Hemodialysis.
    Toxins, 2015, Sep-28, Volume: 7, Issue:10

    Topics: Aged; Aged, 80 and over; Cresols; Cross-Sectional Studies; Female; Glucuronides; Hippurates; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Protein Binding; Renal Dialysis; Renal Insufficiency, Chronic; Serum Albumin; Severity of Illness Index; Sulfuric Acid Esters; Uremia

2015
Indolic uremic solutes enhance procoagulant activity of red blood cells through phosphatidylserine exposure and microparticle release.
    Toxins, 2015, Oct-28, Volume: 7, Issue:11

    Topics: Anticoagulants; Blood Coagulation; Calcium; Cell-Derived Microparticles; Cytosol; Erythrocytes; Factor Xa; Female; Flow Cytometry; Humans; Indican; Indoleacetic Acids; Indoles; Male; Phosphatidylserines; Thromboplastin; Thrombosis; Uremia; Young Adult

2015
The Uremic Toxin Indoxyl-3-Sulfate Induces CYP1A2 In Primary Human Hepatocytes.
    Drug metabolism letters, 2016, Volume: 10, Issue:3

    Topics: Adult; Aged; Cells, Cultured; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Female; Hepatocytes; Humans; Indican; Indoleacetic Acids; Male; Omeprazole; Renal Insufficiency, Chronic; RNA, Messenger; Uremia

2016
Correlations between Plasma Levels of Anionic Uremic Toxins and Clinical Parameters in Hemodialysis Patients.
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2016, Volume: 136, Issue:8

    Topics: Aged; Aged, 80 and over; Biomarkers; Blood Urea Nitrogen; Creatinine; Female; Furans; Glomerular Filtration Rate; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Predictive Value of Tests; Propionates; Renal Dialysis; Renal Insufficiency, Chronic

2016
Tryptophan metabolism, its relation to inflammation and stress markers and association with psychological and cognitive functioning: Tasmanian Chronic Kidney Disease pilot study.
    BMC nephrology, 2016, 11-10, Volume: 17, Issue:1

    Topics: Aged; Aged, 80 and over; Anxiety; Biomarkers; Cognition; Cross-Sectional Studies; Depression; Female; Glomerular Filtration Rate; Humans; Hydrocortisone; Indican; Indoleacetic Acids; Inflammation; Kynurenic Acid; Male; Middle Aged; Neopterin; Oxidative Stress; Pilot Projects; Prospective Studies; Renal Insufficiency, Chronic; Surveys and Questionnaires; Tasmania; Tryptophan

2016
Gut microbiome-related metabolic changes in plasma of antibiotic-treated rats.
    Archives of toxicology, 2017, Volume: 91, Issue:10

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Blood; Body Weight; Eating; Fluoroquinolones; Gastrointestinal Microbiome; Glycerol; Hippurates; Indican; Indoleacetic Acids; Metabolome; Metabolomics; Rats, Wistar; Tetracyclines

2017
Exploring binding characteristics and the related competition of different protein-bound uremic toxins.
    Biochimie, 2017, Volume: 139

    Topics: Binding, Competitive; Case-Control Studies; Chromatography, High Pressure Liquid; Cresols; Hippurates; Humans; Indican; Indoleacetic Acids; Protein Binding; Protein Processing, Post-Translational; Renal Dialysis; Renal Insufficiency, Chronic; Serum Albumin; Sulfuric Acid Esters; Tandem Mass Spectrometry; Toxins, Biological; Uremia

2017
Indole 3-acetic acid, indoxyl sulfate and paracresyl-sulfate do not influence anemia parameters in hemodialysis patients.
    BMC nephrology, 2017, Jul-26, Volume: 18, Issue:1

    Topics: Aged; Aged, 80 and over; Anemia; Biomarkers; Cross-Sectional Studies; Female; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Renal Dialysis; Renal Insufficiency, Chronic; Sulfates

2017
Does Low-Protein Diet Influence the Uremic Toxin Serum Levels From the Gut Microbiota in Nondialysis Chronic Kidney Disease Patients?
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2018, Volume: 28, Issue:3

    Topics: Adult; Aged; Cresols; Diet, Protein-Restricted; Feces; Female; Gastrointestinal Microbiome; Humans; Indican; Indoleacetic Acids; Longitudinal Studies; Male; Middle Aged; Patient Compliance; Renal Insufficiency, Chronic; Sulfuric Acid Esters

2018
Association between Protein-Bound Uremic Toxins and Asymptomatic Cardiac Dysfunction in Patients with Chronic Kidney Disease.
    Toxins, 2018, 12-05, Volume: 10, Issue:12

    Topics: Adult; Arterial Pressure; Cardiac Output; Cresols; Exercise; Glucuronides; Heart Diseases; Heart Rate; Hippurates; Humans; Indican; Indoleacetic Acids; Male; Middle Aged; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Toxins, Biological; Uremia

2018
Selective Transport of Protein-Bound Uremic Toxins in Erythrocytes.
    Toxins, 2019, 07-01, Volume: 11, Issue:7

    Topics: Biological Transport; Cresols; Erythrocytes; Hippurates; Humans; Indican; Indoleacetic Acids; Protein Binding; Renal Dialysis; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Uremia

2019
Uremic toxins promote accumulation of oxidized protein and increased sensitivity to hydrogen peroxide in endothelial cells by impairing the autophagic flux.
    Biochemical and biophysical research communications, 2020, 02-26, Volume: 523, Issue:1

    Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Cresols; Endothelial Cells; Humans; Hydrogen Peroxide; Indican; Indoleacetic Acids; Lysosomes; Mice; NIH 3T3 Cells; Oxidative Stress; RNA-Binding Proteins; Sulfuric Acid Esters; Toxins, Biological

2020
Identification and characterisation of fluorescent substances in spent dialysis fluid.
    The International journal of artificial organs, 2020, Volume: 43, Issue:9

    Topics: Chromatography, High Pressure Liquid; Dialysis Solutions; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Renal Dialysis; Spectrometry, Fluorescence; Tryptophan; Tyrosine

2020
Serum Levels and Removal by Haemodialysis and Haemodiafiltration of Tryptophan-Derived Uremic Toxins in ESKD Patients.
    International journal of molecular sciences, 2020, Feb-23, Volume: 21, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Female; Hemodiafiltration; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis; Renal Insufficiency, Chronic; Tryptophan

2020
Isolation and Quantification of Uremic Toxin Precursor-Generating Gut Bacteria in Chronic Kidney Disease Patients.
    International journal of molecular sciences, 2020, Mar-14, Volume: 21, Issue:6

    Topics: Amino Acids, Aromatic; Bacteria; Cresols; Feces; Gastrointestinal Microbiome; Humans; Indican; Indoleacetic Acids; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Toxins, Biological

2020
Factors of microinflammation in non-diabetic chronic kidney disease: a pilot study.
    BMC nephrology, 2020, 04-21, Volume: 21, Issue:1

    Topics: Bacterial Translocation; Biomarkers; C-Reactive Protein; Female; Gastrointestinal Microbiome; Humans; Indican; Indoleacetic Acids; Inflammation; Kidney Function Tests; Male; Oxidative Stress; Patient Acuity; Pilot Projects; Renal Dialysis; Renal Insufficiency, Chronic; Sulfuric Acid Esters; Uremia

2020
pH-Dependent Protein Binding Properties of Uremic Toxins In Vitro.
    Toxins, 2021, 02-04, Volume: 13, Issue:2

    Topics: Calorimetry; Circular Dichroism; Cresols; Humans; Hydrogen-Ion Concentration; Indican; Indoleacetic Acids; Protein Binding; Protein Conformation; Renal Dialysis; Renal Insufficiency, Chronic; Serum Albumin, Human; Sulfuric Acid Esters; Toxins, Biological; Uremia

2021
Effects of Uremic Toxins on the Binding of Aripiprazole to Human Serum Albumin.
    Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:3

    Topics: Antipsychotic Agents; Aripiprazole; Binding Sites; Cresols; Humans; Indican; Indoleacetic Acids; Oleic Acid; Protein Binding; Serum Albumin, Human; Sulfuric Acid Esters; Uremia

2021
Tryptophan Metabolites Regulate Neuropentraxin 1 Expression in Endothelial Cells.
    International journal of molecular sciences, 2022, Feb-21, Volume: 23, Issue:4

    Topics: Animals; C-Reactive Protein; Carbazoles; Cells, Cultured; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Indican; Indoleacetic Acids; Male; Mice; Mice, Inbred C57BL; Nerve Tissue Proteins; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Renal Insufficiency, Chronic; Toxins, Biological; Tryptophan; Uremia

2022