indole and oxadiazoles

indole has been researched along with oxadiazoles in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (50.00)24.3611
2020's5 (50.00)2.80

Authors

AuthorsStudies
Bolm, C; Mottweiler, J; Reball, J; Zou, LH1
Kumar, A; Kumar, D; Noel, B; Shah, K; Tantak, MP1
Fu, Y; Gong, JX; Guo, YW; Jiang, CS; Wang, ZZ; Xiao, W; Zhang, HY; Zhang, L1
Brancale, A; Cavaliere, A; Hamdy, R; Jones, AT; Kourti, M; Prencipe, F; Westwell, AD; Ziedan, NI1
Abdul Salam, AA; Biswas, S; Joseph, MM; Kamath, PR; Pai, KSR; Sunil, D; Therakathinal, ST1
Awolade, P; Gummidi, L; Kerru, N; Raza, A; Sharma, AK; Singh, P1
Jaswal, S; Kumar, S; Monga, V; Rulhania, S1
Iškauskienė, M; Janovská, L; Kadlecová, A; Malinauskienė, V; Šačkus, A; Voller, J; Žukauskaitė, A1
Kalra, S; Kumar, B; Kumar, D; Kumar, RR; Pathania, S; Singh, PK1
Kaur, N; Kaur, P; Kumar, V; Nayak, SK; Sahu, SK; Wadhwa, P1

Reviews

2 review(s) available for indole and oxadiazoles

ArticleYear
Recent advances in the medicinal chemistry of carbonic anhydrase inhibitors.
    European journal of medicinal chemistry, 2021, Jan-01, Volume: 209

    Topics: Acetazolamide; Animals; Antineoplastic Agents; Antioxidants; Benzenesulfonamides; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Humans; Indoles; Isatin; Molecular Docking Simulation; Organoselenium Compounds; Oxadiazoles; Protein Binding; Protein Isoforms; Pyrimidines; Structure-Activity Relationship; Sulfonamides; Thiazines; Thiophenes; Urea

2021
Alpha-amylase as molecular target for treatment of diabetes mellitus: A comprehensive review.
    Chemical biology & drug design, 2021, Volume: 98, Issue:4

    Topics: 1-Deoxynojirimycin; Acarbose; alpha-Amylases; Benzofurans; Blood Glucose; Diabetes Mellitus; Drug Discovery; Flavonoids; Glycoside Hydrolase Inhibitors; Humans; Hydrazones; Hypoglycemic Agents; Indoles; Inositol; Oxadiazoles; Structure-Activity Relationship

2021

Other Studies

8 other study(ies) available for indole and oxadiazoles

ArticleYear
Transition metal-free direct C-H bond thiolation of 1,3,4-oxadiazoles and related heteroarenes.
    Chemical communications (Cambridge, England), 2012, Nov-28, Volume: 48, Issue:92

    Topics: Benzothiazoles; Caffeine; Carbon; Hydrogen; Indoles; Oxadiazoles; Sulfhydryl Compounds; Transition Elements

2012
Synthesis and biological evaluation of 2-arylamino-5- (3'-indolyl)-1,3,4-oxadiazoles as potent cytotoxic agents.
    ChemMedChem, 2013, Volume: 8, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Cell Line; Cell Proliferation; HeLa Cells; Humans; Indoles; MCF-7 Cells; Microscopy, Fluorescence; Oxadiazoles; Structure-Activity Relationship

2013
Synthesis and biological evaluation of novel marine-derived indole-based 1,2,4-oxadiazoles derivatives as multifunctional neuroprotective agents.
    Bioorganic & medicinal chemistry letters, 2015, Jan-15, Volume: 25, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Survival; Drug Evaluation, Preclinical; Humans; Indoles; Mollusca; Neuroprotective Agents; Oxadiazoles

2015
Virtual screening, SAR, and discovery of 5-(indole-3-yl)-2-[(2-nitrophenyl)amino] [1,3,4]-oxadiazole as a novel Bcl-2 inhibitor.
    Chemical biology & drug design, 2017, Volume: 90, Issue:1

    Topics: Antineoplastic Agents; Binding Sites; Binding, Competitive; Cell Line, Tumor; Cell Proliferation; Drug Design; Enzyme-Linked Immunosorbent Assay; HeLa Cells; Humans; Indoles; Molecular Docking Simulation; Oxadiazoles; Protein Structure, Tertiary; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship

2017
Bisindole-oxadiazole hybrids, T3P
    Journal of biochemical and molecular toxicology, 2017, Volume: 31, Issue:11

    Topics: Anhydrides; Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Movement; Chemistry Techniques, Synthetic; Chlorocebus aethiops; Drug Screening Assays, Antitumor; Humans; Indoles; MCF-7 Cells; Molecular Docking Simulation; Organophosphonates; Oxadiazoles; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship; Vero Cells

2017
Synthesis of indole-tethered [1,3,4]thiadiazolo and [1,3,4]oxadiazolo[3,2-a]pyrimidin-5-one hybrids as anti-pancreatic cancer agents.
    Bioorganic & medicinal chemistry letters, 2020, 11-15, Volume: 30, Issue:22

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Indoles; Molecular Structure; Oxadiazoles; Pancreatic Neoplasms; Pyrimidines; Structure-Activity Relationship; Thiadiazoles

2020
Synthesis of 5-[(1H-indol-3-yl)methyl]-1,3,4-oxadiazole-2(3H)-thiones and their protective activity against oxidative stress.
    Archiv der Pharmazie, 2021, Volume: 354, Issue:6

    Topics: Acetates; Animals; Antioxidants; Caenorhabditis elegans; Cells, Cultured; Friedreich Ataxia; Humans; Indoleacetic Acids; Indoles; Oxadiazoles; Oxidative Stress; Structure-Activity Relationship; Thiones

2021
Investigation of indole functionalized pyrazoles and oxadiazoles as anti-inflammatory agents: Synthesis, in-vivo, in-vitro and in-silico analysis.
    Bioorganic chemistry, 2021, Volume: 114

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biphenyl Compounds; Carrageenan; Cattle; Cyclooxygenase 2; Dose-Response Relationship, Drug; Edema; Female; Humans; Indoles; Male; Molecular Structure; Oxadiazoles; Picrates; Pyrazoles; Rats; Rats, Wistar; Structure-Activity Relationship

2021