indole and indomethacin

indole has been researched along with indomethacin in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Duffy, EM; Jorgensen, WL1
Caron, G; Ermondi, G1
Gestwicki, JE; Reinke, AA; Seh, HY1
Crews, BC; Kalgutkar, AS; Marnett, LJ; Prudhomme, D; Saleh, S1
Abdellatif, KR; Chowdhury, MA; Dong, Y; Huang, Z; Knaus, EE; Velázquez, CA; Yu, G1
Badawi, HM; Förner, W1
Aikawa, S; Ida, Y; Kadota, K; Kashima, Y; Kikuchi, J; Tanino, T; Tozuka, Y; Ueda, H1
Ikeda, A1
da Cruz-Filho, IJ; da Silva, TG; de Almeida, SMV; de Lima, MCA; de Melo, CML; de Miranda, MDS; de Oliveira, JF; Gomes, FOS; Jacob, ÍTT; Moreira, DRM; Peixoto, CA1

Reviews

1 review(s) available for indole and indomethacin

ArticleYear
[Approach for Producing New 3,3,3-Trifluoropropenylation Reagents: Introduction of a 3,3,3-Trifluoroprop-1-enyl Group for Drug Development].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:5

    Topics: Acetylene; Allyl Compounds; Cyclization; Drug Design; Drug Development; Halogenation; Indicators and Reagents; Indoles; Indomethacin; Molecular Conformation

2019

Other Studies

8 other study(ies) available for indole and indomethacin

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
A chemical screening approach reveals that indole fluorescence is quenched by pre-fibrillar but not fibrillar amyloid-beta.
    Bioorganic & medicinal chemistry letters, 2009, Sep-01, Volume: 19, Issue:17

    Topics: Amyloid beta-Peptides; Benzothiazoles; Coloring Agents; Congo Red; Fluorescent Dyes; Indoles; Spectrometry, Fluorescence; Thiazoles

2009
Indolyl esters and amides related to indomethacin are selective COX-2 inhibitors.
    Bioorganic & medicinal chemistry, 2005, Dec-15, Volume: 13, Issue:24

    Topics: Amides; Animals; Cell Line; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Esters; Humans; Indoles; Indomethacin; Inhibitory Concentration 50; Mice; Structure-Activity Relationship

2005
Synthesis and biological evaluation of indomethacin analogs possessing a N-difluoromethyl-1,2-dihydropyrid-2-one ring system: a search for novel cyclooxygenase and lipoxygenase inhibitors.
    Bioorganic & medicinal chemistry letters, 2010, Oct-01, Volume: 20, Issue:19

    Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Edema; Indoles; Indomethacin; Lipoxygenase Inhibitors; Pyridones; Rats; Structure-Activity Relationship

2010
Analysis of the molecular structure and vibrational spectra of the indole based analgesic drug indomethacin.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Apr-05, Volume: 123

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Indoles; Indomethacin; Models, Molecular; Molecular Conformation; Spectrophotometry, Infrared; Spectrum Analysis, Raman

2014
Anti-plasticizing effect of amorphous indomethacin induced by specific intermolecular interactions with PVA copolymer.
    Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:9

    Topics: Calorimetry, Differential Scanning; Crystallization; Glass; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Indoles; Indomethacin; Plasticizers; Polymers; Pyrrolidines; Transition Temperature; Vinyl Compounds

2014
Anti-inflammatory activity of novel thiosemicarbazone compounds indole-based as COX inhibitors.
    Pharmacological reports : PR, 2021, Volume: 73, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Celecoxib; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Edema; Indoles; Indomethacin; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Thiosemicarbazones

2021