Page last updated: 2024-08-25

indole-2-carboxylic acid and navitoclax

indole-2-carboxylic acid has been researched along with navitoclax in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Anderson, DJ; Bruncko, M; Chen, J; Eastham-Anderson, J; Elmore, SW; Fairbrother, WJ; Gierke, S; Jin, S; Kategaya, L; Kovar, P; Leverson, JD; Ludlam, MJ; Nimmer, P; Phillips, DC; Rosenberg, SH; Sampath, D; Sheppard, GS; Smith, M; Souers, AJ; Tahir, SK; Tanaka, A; Tse, C; Wang, L; Wertz, I; Wong, C; Xiao, Y; Xue, J; Zhang, H	1
Anantram, A; Degani, M	1

Reviews

1 review(s) available for indole-2-carboxylic acid and navitoclax

Article	Year
Targeting cancer's Achilles' heel: role of BCL-2 inhibitors in cellular senescence and apoptosis. Future medicinal chemistry, 2019, Volume: 11, Issue:17 Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; Arylsulfonates; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Carboxylic Acids; Cell Line, Tumor; Cellular Senescence; Drug Screening Assays, Antitumor; Gene Expression Regulation; Humans; Hydrophobic and Hydrophilic Interactions; Hydroxyquinolines; Indoles; Molecular Structure; Molecular Targeted Therapy; Myeloid Cell Leukemia Sequence 1 Protein; Protein Binding; Protein Conformation; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Pyrogallol; Pyrroles; Salicylates; Structure-Activity Relationship; Sulfonamides	2019

Article

Year

Targeting cancer's Achilles' heel: role of BCL-2 inhibitors in cellular senescence and apoptosis.

Future medicinal chemistry, 2019, Volume: 11, Issue:17

Topics: Aniline Compounds; Antineoplastic Agents; Apoptosis; Arylsulfonates; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Carboxylic Acids; Cell Line, Tumor; Cellular Senescence; Drug Screening Assays, Antitumor; Gene Expression Regulation; Humans; Hydrophobic and Hydrophilic Interactions; Hydroxyquinolines; Indoles; Molecular Structure; Molecular Targeted Therapy; Myeloid Cell Leukemia Sequence 1 Protein; Protein Binding; Protein Conformation; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Pyrogallol; Pyrroles; Salicylates; Structure-Activity Relationship; Sulfonamides

2019

Other Studies

1 other study(ies) available for indole-2-carboxylic acid and navitoclax

Article	Year
Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax). Cell death & disease, 2015, Jan-15, Volume: 6 Topics: Aniline Compounds; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Carboxylic Acids; Cell Line, Tumor; Cell Survival; Drug Synergism; Humans; Indoles; Membrane Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms; Proto-Oncogene Proteins; Small Molecule Libraries; Sulfonamides	2015

Article

Year

Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax).

Cell death & disease, 2015, Jan-15, Volume: 6

Topics: Aniline Compounds; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Carboxylic Acids; Cell Line, Tumor; Cell Survival; Drug Synergism; Humans; Indoles; Membrane Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms; Proto-Oncogene Proteins; Small Molecule Libraries; Sulfonamides

2015