Page last updated: 2024-08-26

indolactam v and teleocidin b-4

indolactam v has been researched along with teleocidin b-4 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's4 (33.33)18.2507
2000's1 (8.33)29.6817
2010's1 (8.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Endo, Y; Ichinose, T; Itai, A; Kawai, T; Shudo, K1
Driedger, PE; Endo, Y; Itai, A; Mizutani, MY; Ohno, M; Shudo, K; Stabel, S; Takehana, S; Tomioka, N1
Hagiwara, N; Hayashi, H; Irie, K; Ito, Y; Koshimizu, K; Murao, S; Tokuda, H1
Endo, Y; Fujiki, H; Itai, A; Shudo, K1
Hagiwara, N; Irie, K; Koshimizu, K; Tokuda, H1
Endo, Y; Fujiki, H; Hasegawa, M; Hirota, M; Horiuchi, T; Nakayasu, M; Shudo, K; Suganuma, M; Yoshizawa, S1
Hiragun, A; Sato, M; Shudo, K1
Acs, P; Ahmad, S; Blumberg, PM; Bogi, K; Glazer, RI; Kozikowski, AP; Lewin, NE; Ma, D; Modarres, S; Wang, S; Yao, J1
Bhattacharrya, D; Blumberg, PM; Kozikowski, AP; Lewin, NE; Liu, M; Lorenzo, PS; Qiao, L; Wang, S1
Endo, Y; Fukasawa, H; Hashimoto, Y; Shudo, K; Yamaguchi, M1
Neudörfl, JM; Schmalz, HG; Sperlich, J; Stahn, S; Stein, J; Teusch, N1
Abe, I; Mori, T; Morita, I1

Reviews

1 review(s) available for indolactam v and teleocidin b-4

ArticleYear
Enzymatic Formation of Indolactam Scaffold by C-N Bond-Forming Cytochrome P450 Oxidases in Teleocidin Biosynthesis.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2021, Feb-10, Volume: 27, Issue:9

    Topics: Animals; Cyclization; Cytochrome P-450 Enzyme System; Humans; Indoles; Lactams; Lyngbya Toxins

2021

Other Studies

11 other study(ies) available for indolactam v and teleocidin b-4

ArticleYear
Active conformation of a tumor promoter, teleocidin. A molecular dynamics study.
    Journal of medicinal chemistry, 1992, Jun-12, Volume: 35, Issue:12

    Topics: Carcinogens; Crystallization; Lyngbya Toxins; Magnetic Resonance Spectroscopy; Molecular Conformation; Thermodynamics

1992
Clarification of the binding mode of teleocidin and benzolactams to the Cys2 domain of protein kinase Cdelta by synthesis of hydrophobically modified, teleocidin-mimicking benzolactams and computational docking simulation.
    Journal of medicinal chemistry, 1998, Apr-23, Volume: 41, Issue:9

    Topics: Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Carcinogens; Cell Division; Cysteine; Enzyme Activation; HL-60 Cells; Humans; Hydrogen Bonding; Lyngbya Toxins; Models, Molecular; Molecular Mimicry; Monocytes; Protein Binding; Protein Kinase C; Structure-Activity Relationship; Tetrahydronaphthalenes

1998
Structure-activity relationship in the induction of Epstein-Barr virus by teleocidin derivatives.
    International journal of cancer, 1985, Oct-15, Volume: 36, Issue:4

    Topics: Antigens, Viral; Cell Line; Dose-Response Relationship, Drug; Herpesvirus 4, Human; Humans; Indoles; Lactams; Lyngbya Toxins; Structure-Activity Relationship; Virus Replication

1985
[The active structure of tumor promoters].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:12

    Topics: Carcinogens; Indoles; Lactams; Lyngbya Toxins; Protein Kinase C; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1986
The metabolism of indole alkaloid tumor promoter, (-)-indolactam V, which has the fundamental structure of teleocidins, by rat liver microsomes.
    Carcinogenesis, 1987, Volume: 8, Issue:7

    Topics: Animals; Antigens, Viral; Carcinogens; In Vitro Techniques; Indoles; Lactams; Lyngbya Toxins; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Tritium

1987
Synthetic analogues (indolactams) of (-)-indolactam-V are new congeners of the teleocidin class of tumor promoters.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:6

    Topics: Animals; Cell Adhesion; Cell Line; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Indoles; Lactams; Leukemia, Myeloid, Acute; Lyngbya Toxins; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Protein Kinase C; Skin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1987
Effects of synthetic analogues of teleocidin, indolactam-V, on the differentiation of murine pre-adipose cells.
    Cancer letters, 1985, Volume: 25, Issue:3

    Topics: Adipose Tissue; Animals; Cell Differentiation; Cells, Cultured; Depression, Chemical; Dose-Response Relationship, Drug; Indoles; Lactams; Lyngbya Toxins; Mice; Stereoisomerism; Structure-Activity Relationship

1985
Modeling, chemistry, and biology of the benzolactam analogues of indolactam V (ILV). 2. Identification of the binding site of the benzolactams in the CRD2 activator-binding domain of PKCdelta and discovery of an ILV analogue of improved isozyme selectivit
    Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

    Topics: Antineoplastic Agents; Binding Sites; Binding, Competitive; Breast Neoplasms; Cell Division; Crystallography, X-Ray; Enzyme Inhibitors; Female; Humans; Hydrogen Bonding; Indoles; Isoenzymes; Lactams; Lyngbya Toxins; Models, Molecular; Molecular Conformation; Molecular Structure; Mutagenesis, Site-Directed; Protein Kinase C; Tumor Cells, Cultured

1997
Probing the binding of indolactam-V to protein kinase C through site-directed mutagenesis and computational docking simulations.
    Journal of medicinal chemistry, 1999, Sep-09, Volume: 42, Issue:18

    Topics: Animals; Binding Sites; Computer Simulation; Drug Design; Hydrogen Bonding; Indoles; Lactams; Lyngbya Toxins; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Phorbol Esters; Protein Binding; Protein Kinase C; Structure-Activity Relationship

1999
Enhancing effect of tumor promoters, phorbol esters and teleocidins on nuclear receptor-mediated transcription.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:12

    Topics: Animals; Carcinogens; Chlorocebus aethiops; COS Cells; Gene Expression Regulation; Genes, Reporter; Humans; Indoles; Lactams; Luciferases; Lyngbya Toxins; Nuclear Receptor Subfamily 1, Group F, Member 1; Okadaic Acid; Plasmids; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Retinoic Acid Receptor alpha; Tetradecanoylphorbol Acetate; Thapsigargin; Thymidine Kinase; Trans-Activators; Transcription, Genetic; Transfection

2000
Synthetic Indolactam V Analogues as Inhibitors of PAR2-Induced Calcium Mobilization in Triple-Negative Breast Cancer Cells.
    ChemMedChem, 2018, 01-22, Volume: 13, Issue:2

    Topics: Antineoplastic Agents; Calcium; Cell Line, Tumor; Cell Movement; Cell Survival; Humans; Indoles; Lactams; Lyngbya Toxins; Molecular Structure; Protein Kinase C; Receptor, PAR-2; Structure-Activity Relationship; Triple Negative Breast Neoplasms

2018