Page last updated: 2024-08-26

indobufen and thromboxane b2

indobufen has been researched along with thromboxane b2 in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19904 (26.67)18.7374
1990's7 (46.67)18.2507
2000's1 (6.67)29.6817
2010's2 (13.33)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Bonomi, E; Canevari, A; Grignani, G; Milanesi, G; Pacchiarini, L; Tacconi, F; Zucchella, M1
Di Somma, M; Ferrario, R; Patrignani, P; Patrono, C; Romanzini, L; Volpi, D1
Cerletti, C; Colombo, M; Manarini, S; Tavani, A1
Bianchi, C; Ciabattoni, G; Coppola, E; Mariello, F; Natale, A; Rebuzzi, AG1
Fabris, F; Gerunda, GE; Girolami, A; Luzzatto, G; Zangrandi, F1
Colli, S; Lavezzari, M; Maderna, P; Mannucci, L; Sirtori, CR; Tremoli, E1
Bevilacqua, C; Cattaneo, M; Lecchi, A; Mannucci, PM1
Carriero, MR; Cerletti, C; de Gaetano, G; Mussoni, L1
Celi, V; Chello, M; Colonna, A; Marchese, AR; Mastroroberto, P; Romano, F1
Cipollone, F; Cuccurullo, F; Greco, A; Liuzzo, G; Maseri, A; Padovano, R; Panara, MR; Patrignani, P; Patrono, C; Quaranta, G; Rebuzzi, AG1
Alessandrini, P; Bon, GB; Bucciarelli, T; Ciabattoni, G; Cipollone, F; Costantini, F; Davi, G; Mezzetti, A; Minotti, G; Patrono, C1
Banfi, C; Barbieri, SS; Brambilla, M; Colli, S; Eligini, S; Saliola, M; Tremoli, E; Violi, F1
Acconcia, MC; BarillĂ , F; Dominici, T; Gaudio, C; Mangieri, E; Paravati, V; Pellicano, M; Pulcinelli, FM; Tanzilli, G; Torromeo, C1
Choi, HI; Lee, JY; Sung, KC1
Abdus, S; Bai, J; Eikelboom, JW; Gong, X; Gu, Q; Li, C; Lu, Y; Mei, L; Shi, L; Tan, C; Ullah, I; Wang, G; Yang, M; Ye, Z1

Trials

5 trial(s) available for indobufen and thromboxane b2

ArticleYear
Effects of indobufen on platelet thromboxane B2 production in patients with myocardial infarction.
    European journal of clinical pharmacology, 1990, Volume: 39, Issue:1

    Topics: Adult; Aged; Blood Platelets; Female; Humans; Isoindoles; Male; Middle Aged; Myocardial Infarction; Phenylbutyrates; Platelet Aggregation Inhibitors; Thromboxane B2

1990
Reduction by indobufen of neutrophil activation in peripheral arterial occlusive disease.
    Journal of cardiovascular pharmacology, 1996, Volume: 27, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Arterial Occlusive Diseases; Cyclooxygenase Inhibitors; Humans; Intermittent Claudication; Isoindoles; Lactic Acid; Middle Aged; Neutrophil Activation; Phenylbutyrates; Platelet Aggregation Inhibitors; Thromboxane B2

1996
Differential suppression of thromboxane biosynthesis by indobufen and aspirin in patients with unstable angina.
    Circulation, 1997, Aug-19, Volume: 96, Issue:4

    Topics: Aged; Angina, Unstable; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Isoenzymes; Isoindoles; Male; Membrane Proteins; Middle Aged; Phenylbutyrates; Prostaglandin-Endoperoxide Synthases; Reference Values; Thromboxane A2; Thromboxane B2

1997
Clopidogrel plus indobufen in acute coronary syndrome patients with hypersensitivity to aspirin undergoing percutaneous coronary intervention.
    Platelets, 2013, Volume: 24, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Isoindoles; Male; Middle Aged; Percutaneous Coronary Intervention; Phenylbutyrates; Platelet Aggregation Inhibitors; Risk Factors; Thromboxane B2; Ticlopidine; Treatment Outcome

2013
Pharmacodynamic effects of indobufen compared with aspirin in patients with coronary atherosclerosis.
    European journal of clinical pharmacology, 2021, Volume: 77, Issue:12

    Topics: Aged; Aspirin; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2

2021

Other Studies

10 other study(ies) available for indobufen and thromboxane b2

ArticleYear
Thromboxane production by platelets during tumor cell-induced platelet activation.
    Invasion & metastasis, 1991, Volume: 11, Issue:2

    Topics: Adult; Apyrase; Blood Platelets; Dose-Response Relationship, Drug; Hirudins; Humans; Iodoacetates; Iodoacetic Acid; Isoindoles; Neoplasms; Phenylbutyrates; Phenylmercury Compounds; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Radioimmunoassay; Thromboxane B2

1991
Effects of racemic, S- and R-indobufen on cyclooxygenase and lipoxygenase activities in human whole blood.
    European journal of pharmacology, 1990, Nov-20, Volume: 191, Issue:1

    Topics: Adult; Arachidonate 5-Lipoxygenase; Calcimycin; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; In Vitro Techniques; Isoindoles; Leukotriene B4; Lipoxygenase Inhibitors; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Stereoisomerism; Thromboxane B2

1990
The (+)-enantiomer is responsible for the antiplatelet and anti-inflammatory activity of (+/-)-indobufen.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:12

    Topics: Animals; Gastric Mucosa; Humans; Isoindoles; Phenylbutyrates; Platelet Aggregation; Platelet Aggregation Inhibitors; Pleurisy; Rats; Rats, Inbred Strains; Stereoisomerism; Thromboxane B2

1990
Failure of two anti-platelet drugs (indobufen and dipyridamole) to improve thrombocytopenia in liver cirrhosis.
    Acta haematologica, 1987, Volume: 77, Issue:2

    Topics: Aged; beta-Thromboglobulin; Blood Platelets; Dipyridamole; Female; Humans; Isoindoles; Liver Cirrhosis; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation; Platelet Count; Platelet Factor 4; Thrombocytopenia; Thromboxane B2

1987
Indobufen is a potent inhibitor of whole blood aggregation in patients with a high atherosclerotic risk.
    Thrombosis research, 1987, Nov-15, Volume: 48, Issue:4

    Topics: Adult; Aged; Arteriosclerosis; Blood Coagulation; Dose-Response Relationship, Drug; Female; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Risk Factors; Thromboxane B2

1987
In vitro and ex vivo effects of indobufen on human platelet aggregation, the release reaction and thromboxane B2 production.
    Haemostasis, 1987, Volume: 17, Issue:5

    Topics: Adenosine Triphosphate; Adult; Blood Platelets; Female; Humans; Isoindoles; Male; Phenylbutyrates; Platelet Aggregation; Thromboxane B2

1987
Low dose aspirin does not prevent fibrinolytic response to venous occlusion.
    Biochemical pharmacology, 1986, Sep-15, Volume: 35, Issue:18

    Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Aspirin; Fibrinolysis; Hematocrit; Humans; Isoindoles; Phenylbutyrates; Thrombosis; Thromboxane B2

1986
In vivo formation of 8-Epi-prostaglandin F2 alpha is increased in hypercholesterolemia.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:11

    Topics: Antioxidants; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Cyclooxygenase Inhibitors; Dinoprost; Female; Humans; Hypercholesterolemia; Isoindoles; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Phenylbutyrates; Platelet Activation; Platelet Aggregation Inhibitors; Reactive Oxygen Species; Thromboxane B2; Vitamin E

1997
Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism.
    Cardiovascular research, 2006, Volume: 69, Issue:1

    Topics: Cells, Cultured; Cyclooxygenase Inhibitors; Depression, Chemical; Dinoprostone; Flow Cytometry; Humans; Isoindoles; Lipopolysaccharides; Monocytes; Phenylbutyrates; Thromboplastin; Thromboxane A2; Thromboxane B2; Thromboxanes

2006
Comparison of aspirin and indobufen in healthy volunteers.
    Platelets, 2016, Volume: 27, Issue:2

    Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Cross-Over Studies; Drug Administration Schedule; Female; Healthy Volunteers; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandin-Endoperoxide Synthases; Thromboxane B2

2016