Page last updated: 2024-08-26

indobufen and aspirin

indobufen has been researched along with aspirin in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199012 (31.58)18.7374
1990's15 (39.47)18.2507
2000's3 (7.89)29.6817
2010's4 (10.53)24.3611
2020's4 (10.53)2.80

Authors

AuthorsStudies
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Vinazzer, H1
Bergamaschi, M; Ceserani, R; Pierucci, L; Pogliani, E; Spelta, A1
Avruscio, GP; Cordiano, I; Fabris, F; Girolami, A; Randi, ML; Steffan, A1
Bregani, R; Corneo, G; Fowst, C; Pogliani, EM1
Cataldo, G; Marubini, E; Mezzanotte, G; Montoro, C; Petroccione, A; Rovelli, F1
Belcaro, G; De Simone, P1
Peregrin, J; Pirk, J; Rohn, V1
Belcaro, G; Cesarone, MR; De Cenzo, A; Errichi, BM; Laurora, G; Marinucci, R1
Cantatore, G; Cerillo, A; Donati, PA; Donzelli, R; Maio, N; Muras, I; Perla, N; Villano, M; Vizioli, L1
Grasselli, S; Gresele, P; Guerciolini, R; Iadevaia, V; Nenci, GG; Parise, P1
Irwin, JT; Jennings, SA; Lane, IF; McCollum, CN; Meek, AC; Poskitt, KR1
Carriero, MR; Cerletti, C; de Gaetano, G; Mussoni, L1
Corvi, G; Fuccella, LM; Mandelli, V; Pogliani, E1
Carrieri, P; Fioretti, A; Indaco, A; Iorillo, L; Orefice, G1
Bergamaschi, M; Branzoli, U; Pierucci, L1
Akman, N1
Brantmark, B; Hanson, A; Melander, A; Nilsson, C; Wåhlin-Boll, E1
Coccheri, S; Morocutti, C1
Beton, D; Campbell, C; Critchley, A; Lawson, RA; Nair, U; Rajah, SM; Rees, M; Saunders, N; Walker, D; Williams, G1
Braga, M; Cataldo, G; Lavezzari, M; Marubini, E; Pirotta, N; Rovelli, F1
Mach, T; Pirk, J; Rohn, V1
Bernini, W; Biagi, G; Coccheri, S; De Caterina, R; Giannessi, D; Lavezzari, M; Lazzerini, G; Stragliotto, E1
Cipollone, F; Cuccurullo, F; Greco, A; Liuzzo, G; Maseri, A; Padovano, R; Panara, MR; Patrignani, P; Patrono, C; Quaranta, G; Rebuzzi, AG1
Alessandrini, P; Bon, GB; Bucciarelli, T; Ciabattoni, G; Cipollone, F; Costantini, F; Davi, G; Mezzetti, A; Minotti, G; Patrono, C1
Cataldo, G; Heiman, F; Lavezzari, M; Marubini, E1
Cohen, H; Ebrahim, S; Taylor, FC1
Prisco, D1
Pengo, V1
Collet, JP1
Bartkova, A; Herzig, R; Hlustik, P; Kanovsky, P; Kovacik, M; Kral, M; Sanak, D; Skoloudik, D; Vlachova, I1
Acconcia, MC; Barillà, F; Dominici, T; Gaudio, C; Mangieri, E; Paravati, V; Pellicano, M; Pulcinelli, FM; Tanzilli, G; Torromeo, C1
Choi, HI; Lee, JY; Sung, KC1
Fang, W; Gou, X; Hou, K; Li, F; Li, Y; Lv, N; Xu, D1
Abdus, S; Bai, J; Eikelboom, JW; Gong, X; Gu, Q; Li, C; Lu, Y; Mei, L; Shi, L; Tan, C; Ullah, I; Wang, G; Yang, M; Ye, Z1
Bath, PM; Chen, W; Dong, Q; Jiang, Y; Jing, J; Johnston, SC; Li, H; Lin, J; Meng, X; Pan, Y; Wang, Y; Xu, AD1
Chen, M; Cheng, K; Ge, J; Huang, J; Lan, J; Li, G; Qian, J; Wang, X; Wang, Y; Wei, G; Wu, H; Xu, L; Zhang, C; Zhang, H; Zhao, X1

Reviews

4 review(s) available for indobufen and aspirin

ArticleYear
Systematic review of long term anticoagulation or antiplatelet treatment in patients with non-rheumatic atrial fibrillation.
    BMJ (Clinical research ed.), 2001, Feb-10, Volume: 322, Issue:7282

    Topics: Anticoagulants; Aspirin; Atrial Fibrillation; Hemorrhage; Humans; Isoindoles; Phenylbutyrates; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Assessment; Treatment Outcome; Warfarin

2001
[Thromboembolism in non-rheumatic atrial fibrillation].
    Haematologica, 2001, Volume: 86, Issue:9 Suppl

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Clinical Trials as Topic; Consensus Development Conferences as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Electric Countershock; Female; Hemorrhage; Humans; Incidence; International Normalized Ratio; Isoenzymes; Isoindoles; Male; Membrane Proteins; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Prospective Studies; Prostaglandin-Endoperoxide Synthases; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Thromboembolism; Treatment Outcome; Warfarin

2001
[Management of aspirin discontinuation in stable coronary heart disease prior to elective surgery].
    Annales de cardiologie et d'angeiologie, 1999, Volume: 48, Issue:9-10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Coronary Disease; Cyclooxygenase Inhibitors; Drug Administration Schedule; Drug Monitoring; Elective Surgical Procedures; Flurbiprofen; Humans; Isoindoles; Metabolic Clearance Rate; Phenylbutyrates; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Preoperative Care; Risk Factors; Time Factors

1999
Oral antiplatelet therapy in stroke prevention. Minireview.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2010, Volume: 154, Issue:3

    Topics: Administration, Oral; Aspirin; Clopidogrel; Dipyridamole; Drug Combinations; Humans; Ischemic Attack, Transient; Isoindoles; Phenylbutyrates; Platelet Aggregation Inhibitors; Stroke; Ticlopidine

2010

Trials

16 trial(s) available for indobufen and aspirin

ArticleYear
Indobufen versus dipyridamole plus aspirin in the treatment of patients with peripheral atherosclerotic disease.
    Journal of medicine, 1992, Volume: 23, Issue:2

    Topics: Aged; Arteriosclerosis; Aspirin; Dipyridamole; Drug Therapy, Combination; Female; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Random Allocation

1992
Bleeding time and antiplatelet agents in normal volunteers.
    International journal of clinical & laboratory research, 1992, Volume: 22, Issue:1

    Topics: Adolescent; Adult; Aspirin; Bleeding Time; Female; Humans; Isoindoles; Male; Phenylbutyrates; Platelet Aggregation Inhibitors; Reference Values; Ticlopidine

1992
A linear model suitable for assessing graft patency in controlled clinical trials. SINBA Group.
    Controlled clinical trials, 1990, Volume: 11, Issue:6

    Topics: Anastomosis, Surgical; Angiography; Aspirin; Clinical Trials as Topic; Coronary Artery Bypass; Dipyridamole; Drug Therapy, Combination; Graft Occlusion, Vascular; Humans; Isoindoles; Models, Statistical; Phenylbutyrates; Platelet Aggregation Inhibitors; Probability; Regression Analysis; Vascular Patency

1990
Long-term evaluation of indobufen in peripheral vascular disease.
    Angiology, 1991, Volume: 42, Issue:1

    Topics: Aspirin; Diabetes Complications; Female; Humans; Intermittent Claudication; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Walking

1991
The effect of ibustrin on early aortocoronary bypass patency.
    Cor et vasa, 1990, Volume: 32, Issue:3

    Topics: Angiography, Digital Subtraction; Aspirin; Coronary Angiography; Coronary Artery Bypass; Coronary Disease; Dipyridamole; Graft Occlusion, Vascular; Humans; Isoindoles; Phenylbutyrates; Platelet Aggregation Inhibitors; Prospective Studies

1990
[Embolic complications in atrial fibrillation. Data of the Studio Italiano Fibrillation Atriale (SIFA)].
    Il Giornale di chirurgia, 1995, Volume: 16, Issue:3

    Topics: Adult; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Brain Ischemia; Cerebrovascular Disorders; Embolism; Female; Follow-Up Studies; Humans; Isoindoles; Italy; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Risk Factors; Time Factors; Warfarin

1995
Aspirin and prevention of stroke.
    Lancet (London, England), 1994, Jan-22, Volume: 343, Issue:8891

    Topics: Aspirin; Atrial Fibrillation; Cerebrovascular Disorders; Humans; Isoindoles; Phenylbutyrates; Platelet Aggregation Inhibitors; Warfarin

1994
Effects of antiplatelet therapy with indobufen or aspirin-dipyridamole on graft patency one year after coronary artery bypass grafting.
    The Journal of thoracic and cardiovascular surgery, 1994, Volume: 107, Issue:4

    Topics: Adolescent; Adult; Aged; Aspirin; Coronary Artery Bypass; Dipyridamole; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Occlusion, Vascular; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Postoperative Care; Prospective Studies; Time Factors

1994
Factors influencing 1-year patency of coronary artery saphenous vein grafts. Studio Indobufene nel Bypass Aortocoronarico (SINBA).
    Circulation, 1993, Volume: 88, Issue:5 Pt 2

    Topics: Aspirin; Coronary Angiography; Coronary Artery Bypass; Dipyridamole; Double-Blind Method; Female; Graft Occlusion, Vascular; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Prospective Studies; Regression Analysis; Risk Factors; Saphenous Vein

1993
[The effect of indobufen on aortocoronary bypass patency after 1 week and after 1 year].
    Cor et vasa, 1993, Volume: 35, Issue:4

    Topics: Adult; Aged; Aspirin; Coronary Artery Bypass; Dipyridamole; Female; Graft Occlusion, Vascular; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Time Factors; Vascular Patency

1993
A prostacyclin-sparing effect of indobufen vs. aspirin.
    Thrombosis and haemostasis, 1996, Volume: 75, Issue:3

    Topics: Adult; Aspirin; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Epoprostenol; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Prospective Studies; Prostaglandins; Reference Values

1996
Differential suppression of thromboxane biosynthesis by indobufen and aspirin in patients with unstable angina.
    Circulation, 1997, Aug-19, Volume: 96, Issue:4

    Topics: Aged; Angina, Unstable; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Isoenzymes; Isoindoles; Male; Membrane Proteins; Middle Aged; Phenylbutyrates; Prostaglandin-Endoperoxide Synthases; Reference Values; Thromboxane A2; Thromboxane B2

1997
Clopidogrel plus indobufen in acute coronary syndrome patients with hypersensitivity to aspirin undergoing percutaneous coronary intervention.
    Platelets, 2013, Volume: 24, Issue:3

    Topics: Acute Coronary Syndrome; Aged; Aspirin; Clopidogrel; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; Isoindoles; Male; Middle Aged; Percutaneous Coronary Intervention; Phenylbutyrates; Platelet Aggregation Inhibitors; Risk Factors; Thromboxane B2; Ticlopidine; Treatment Outcome

2013
Pharmacodynamic effects of indobufen compared with aspirin in patients with coronary atherosclerosis.
    European journal of clinical pharmacology, 2021, Volume: 77, Issue:12

    Topics: Aged; Aspirin; Coronary Artery Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation; Platelet Aggregation Inhibitors; Thromboxane B2

2021
Indobufen versus aspirin in acute ischaemic stroke (INSURE): rationale and design of a multicentre randomised trial.
    Stroke and vascular neurology, 2022, Volume: 7, Issue:5

    Topics: Aspirin; Brain Ischemia; Hemorrhage; Humans; Ischemic Stroke; Platelet Aggregation Inhibitors; Stroke; Treatment Outcome

2022
Indobufen or Aspirin on Top of Clopidogrel After Coronary Drug-Eluting Stent Implantation (OPTION): A Randomized, Open-Label, End Point-Blinded, Noninferiority Trial.
    Circulation, 2023, 01-17, Volume: 147, Issue:3

    Topics: Aspirin; Clopidogrel; Drug Therapy, Combination; Drug-Eluting Stents; Hemorrhage; Humans; Ischemic Stroke; Myocardial Infarction; Percutaneous Coronary Intervention; Platelet Aggregation Inhibitors; Thrombosis; Treatment Outcome; Troponin

2023

Other Studies

18 other study(ies) available for indobufen and aspirin

ArticleYear
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
[Clinical-experimental studies on the inhibition of thrombocyte function with acetylsalicylic acid and with indobufen].
    Folia haematologica (Leipzig, Germany : 1928), 1979, Volume: 106, Issue:5-6

    Topics: Aspirin; Humans; Indoles; Isoindoles; Phenylbutyrates; Platelet Aggregation; Platelet Factor 3; Platelet Factor 4

1979
Indobufen, a new inhibitor of platelet aggregation. Studies in guinea pigs.
    Pharmacological research communications, 1979, Volume: 11, Issue:3

    Topics: Animals; Aspirin; Blood Platelets; Blood Specimen Collection; Dipyridamole; Guinea Pigs; In Vitro Techniques; Indoles; Indomethacin; Isoindoles; Phenylbutyrates; Platelet Aggregation; Prostaglandins; Prothrombin Time; Serotonin; Thrombin; Thromboxane A2; Time Factors

1979
[Chronic treatment of vascular diseases with indobufen].
    Minerva cardioangiologica, 1989, Volume: 37, Issue:5

    Topics: Adult; Aged; Aspirin; Cerebrovascular Disorders; Dipyridamole; Humans; Isoindoles; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Vascular Diseases; Veins

1989
[Prevention of thromboses in vascular microanastomoses. Experimental study on the role of anti-aggregant drugs. Preliminary remarks].
    Minerva chirurgica, 1988, Oct-15, Volume: 43, Issue:19

    Topics: Animals; Aspirin; Isoindoles; Male; Microsurgery; Phenylbutyrates; Platelet Aggregation Inhibitors; Postoperative Complications; Rats; Rats, Inbred Strains; Thrombosis; Vascular Surgical Procedures

1988
In vitro and ex vivo effects of indobufen on red blood cell deformability.
    European journal of clinical pharmacology, 1987, Volume: 32, Issue:2

    Topics: Aspirin; Drug Interactions; Erythrocyte Deformability; Humans; In Vitro Techniques; Isoindoles; Phenylbutyrates; Vascular Diseases

1987
Effect of the cyclo-oxygenase inhibitor indobufen on platelet accumulation in prosthetic vascular grafts.
    The British journal of surgery, 1986, Volume: 73, Issue:7

    Topics: Animals; Aspirin; Blood Vessel Prosthesis; Dipyridamole; Disease Models, Animal; Dogs; Drug Evaluation; Graft Occlusion, Vascular; Isoindoles; Phenylbutyrates; Platelet Aggregation

1986
Low dose aspirin does not prevent fibrinolytic response to venous occlusion.
    Biochemical pharmacology, 1986, Sep-15, Volume: 35, Issue:18

    Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Aspirin; Fibrinolysis; Hematocrit; Humans; Isoindoles; Phenylbutyrates; Thrombosis; Thromboxane B2

1986
Preliminary human pharmacology studies on the inhibition of platelet aggregation by indobufen (K 3920).
    Haematologica, 1981, Volume: 66, Issue:2

    Topics: Aspirin; Dose-Response Relationship, Drug; Humans; Indoles; Isoindoles; Oxazoles; Phenylbutyrates; Platelet Aggregation

1981
A comparative study between indobufen and acetylsalicylic acid on beta-thromboglobulin, platelet factor 4 and platelet aggregation in patients with transient ischemic attacks.
    Acta neurologica, 1984, Volume: 6, Issue:2

    Topics: Aspirin; Beta-Globulins; beta-Thromboglobulin; Humans; Ischemic Attack, Transient; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation; Platelet Factor 4

1984
Inhibitory activity of indobufen (*) on platelet aggregation in vivo.
    Pharmacological research communications, 1984, Volume: 16, Issue:10

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Depression, Chemical; Isoindoles; Lethal Dose 50; Male; Mice; Phenylbutyrates; Platelet Aggregation

1984
The effect of acetylsalicylic acid. Dipyridamole and K 3920 on the secretion of platelet factor 4.
    Haematologica, 1980, Volume: 65, Issue:4

    Topics: Adenosine Diphosphate; Aspirin; Blood Coagulation Factors; Blood Platelets; Collagen; Dipyridamole; Epinephrine; Humans; Indoles; Isoindoles; Phenylbutyrates; Platelet Factor 4

1980
High-pressure liquid chromatographic determination of acetylsalicylic acid, salicylic acid, diflunisal, indomethacin, indoprofen and indobufen.
    European journal of clinical pharmacology, 1981, Volume: 20, Issue:5

    Topics: Anti-Inflammatory Agents; Aspirin; Chromatography, High Pressure Liquid; Diflunisal; Humans; Indoles; Indomethacin; Indoprofen; Isoindoles; Phenylbutyrates; Salicylates

1981
In vivo formation of 8-Epi-prostaglandin F2 alpha is increased in hypercholesterolemia.
    Arteriosclerosis, thrombosis, and vascular biology, 1997, Volume: 17, Issue:11

    Topics: Antioxidants; Aspirin; Cardiovascular Diseases; Cross-Sectional Studies; Cyclooxygenase Inhibitors; Dinoprost; Female; Humans; Hypercholesterolemia; Isoindoles; Lipid Peroxidation; Lipoproteins, LDL; Male; Middle Aged; Phenylbutyrates; Platelet Activation; Platelet Aggregation Inhibitors; Reactive Oxygen Species; Thromboxane B2; Vitamin E

1997
Indobufen compared with aspirin and dipyridamole on graft patency after coronary artery bypass surgery: results of a combined analysis.
    Coronary artery disease, 1998, Volume: 9, Issue:4

    Topics: Aspirin; Coronary Artery Bypass; Cyclooxygenase Inhibitors; Dipyridamole; Drug Therapy, Combination; Female; Graft Occlusion, Vascular; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Radiography; Randomized Controlled Trials as Topic

1998
[Guidelines for antithrombotic therapy in atrial fibrillation: what the Italian Hemostasis and Thrombosis Society thinks].
    Haematologica, 2001, Volume: 86, Issue:9 Suppl

    Topics: Adult; Aged; Aged, 80 and over; Anticoagulants; Aspirin; Atrial Fibrillation; Comorbidity; Diabetes Complications; Double-Blind Method; Fibrinolytic Agents; Heart Valve Diseases; Hemorrhage; Humans; Hypertension; Ischemic Attack, Transient; Isoindoles; Middle Aged; Phenylbutyrates; Platelet Aggregation Inhibitors; Randomized Controlled Trials as Topic; Risk Factors; Stroke; Thromboembolism; Warfarin

2001
Comparison of aspirin and indobufen in healthy volunteers.
    Platelets, 2016, Volume: 27, Issue:2

    Topics: Adenosine Diphosphate; Adolescent; Adult; Aged; Arachidonic Acid; Aspirin; Blood Platelets; Cross-Over Studies; Drug Administration Schedule; Female; Healthy Volunteers; Humans; Isoindoles; Male; Middle Aged; Phenylbutyrates; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Prostaglandin-Endoperoxide Synthases; Thromboxane B2

2016
Pretreatment of Indobufen and Aspirin and their Combinations with Clopidogrel or Ticagrelor Alleviates Inflammasome Mediated Pyroptosis Via Inhibiting NF-κB/NLRP3 Pathway in Ischemic Stroke.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2021, Volume: 16, Issue:4

    Topics: Animals; Aspirin; Brain Ischemia; Clopidogrel; Inflammasomes; Ischemic Stroke; Isoindoles; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Phenylbutyrates; Pyroptosis; Rats; Reperfusion Injury; Stroke; Ticagrelor

2021