indirubin has been researched along with staurosporine in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoda, N; Maqbool, M; Mobashir, M | 1 |
| Cheng, X; Christ, J; Eisenbrand, G; Merz, KH; Muehlbeyer, S; Thommet, A; Vatter, S; Wölfl, S; Zeller, J | 1 |
| Damiens, E; Meijer, L | 1 |
| Bibb, JA; Biernat, J; Eisenbrand, G; Garnier, M; Greengard, P; Hoessel, R; Leclerc, S; Mandelkow, EM; Marko, D; Meijer, L; Snyder, GL; Wu, YZ | 1 |
| Bertrand, JA; Cristiani, C; Flocco, M; Kalisz, HM; Knapp, S; Thieffine, S; Valsasina, B; Vulpetti, A | 1 |
| Archontis, G; Bischler, N; Hayes, JM; Lamprakis, C; Oikonomakos, NG; Sarrou, J; Skaltsounis, AL; Skamnaki, VT; Zographos, SE | 1 |
2 review(s) available for indirubin and staurosporine
| Article | Year |
|---|---|
Pivotal role of glycogen synthase kinase-3: A therapeutic target for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Diabetes Mellitus; Glycogen Synthase Kinase 3; Hippocampus; Humans; Hypoglycemic Agents; Inflammation; Molecular Targeted Therapy; Neoplasms; Protein Kinase Inhibitors | 2016 |
[Chemical inhibitors of cyclic-dependent kinases: preclinical and clinical study].
Topics: Animals; Antineoplastic Agents; Benzazepines; Cyclin-Dependent Kinases; Enzyme Inhibitors; Flavonoids; Humans; Indoles; Piperidines; Purines; Staurosporine | 2000 |
4 other study(ies) available for indirubin and staurosporine
| Article | Year |
|---|---|
Identification of a Water-Soluble Indirubin Derivative as Potent Inhibitor of Insulin-like Growth Factor 1 Receptor through Structural Modification of the Parent Natural Molecule.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Chemistry Techniques, Synthetic; Drug Screening Assays, Antitumor; Humans; Indoles; Oximes; Protein Kinase Inhibitors; Receptor, IGF Type 1; Signal Transduction; Solubility; Structure-Activity Relationship | 2017 |
Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?
Topics: Adenosine Triphosphate; Alkaloids; Alzheimer Disease; Animals; Antibiotics, Antineoplastic; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Cyclin B; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Dopamine and cAMP-Regulated Phosphoprotein 32; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Indoles; Inhibitory Concentration 50; Mice; Molecular Structure; Neostriatum; Nerve Tissue Proteins; Phosphoproteins; Phosphorylation; Phosphothreonine; Piperidines; Staurosporine; tau Proteins | 2001 |
Structural characterization of the GSK-3beta active site using selective and non-selective ATP-mimetic inhibitors.
Topics: Adenosine Triphosphate; Antibiotics, Antineoplastic; Benzazepines; Binding Sites; Binding, Competitive; CDC2 Protein Kinase; Crystallography, X-Ray; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Growth Inhibitors; Humans; Indoles; Maleimides; Molecular Mimicry; Phosphorylation; Protein Conformation; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Staurosporine; Structure-Activity Relationship | 2003 |
Kinetics, in silico docking, molecular dynamics, and MM-GBSA binding studies on prototype indirubins, KT5720, and staurosporine as phosphorylase kinase ATP-binding site inhibitors: the role of water molecules examined.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Base Sequence; Carbazoles; DNA Primers; Indoles; Kinetics; Molecular Dynamics Simulation; Molecular Sequence Data; Phosphorylase Kinase; Pyrroles; Sequence Homology, Amino Acid; Staurosporine; Water | 2011 |