Page last updated: 2024-08-21

indican and 4-cresol

indican has been researched along with 4-cresol in 33 studies

Research

Studies (33)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (9.09)	18.7374
1990's	1 (3.03)	18.2507
2000's	6 (18.18)	29.6817
2010's	13 (39.39)	24.3611
2020's	10 (30.30)	2.80

Authors

Authors	Studies
Lawrie, CA; Renwick, AG	1
George, CF; Lawrie, CA; Renwick, AG; Thakrar, A	1
Tamm, AO	1
Aiba, Y; Hida, M; Koga, Y; Satoh, T; Sawamura, S; Suzuki, N	1
De Smet, R; Dhondt, A; Duym, P; Lameire, N; Lesaffer, G; Vanholder, R	1
De Smet, R; Lameire, N; Vanholder, R	1
Berland, Y; Brunet, P; Cerini, C; Dou, L	1
Berland, Y; Bertrand, E; Brunet, P; Cerini, C; Dou, L; Faure, V; Sampol, J; Vanholder, R	1
Berland, Y; Brunet, P; Cerini, C; Dignat-George, F; Dou, L; Faure, V; Sabatier, F; Sampol, J	1
Dinh, DC; Hostetter, TH; Meyer, TW; Miller, JD; Peattie, JW; Recht, NS; Walther, JL	1
Chen, HH; Chen, YC; Lin, CJ; Pan, CF; Sun, FJ; Wu, CJ	1
Furukubo, T; Higuchi, K; Hirata, S; Izumi, S; Nishiguchi, K; Otagiri, M; Shima, D; Takara, K; Tsujimoto, M; Yamakawa, T; Yokota, H	1
Chen, CH; Cheng, CH; Chuang, YW; Huang, ST; Shu, KH; Wu, MJ; Yu, TM	1
Eloot, S; Glorieux, G; Neirynck, N; Pletinck, A; Schepers, E; Vanholder, R	1
Funk, BA; Hostetter, TH; Meyer, TW; Plummer, NS; Sirich, TL	1
Burdzińska, A; Gala, K; Idziak, M; Pączek, L; Pędzisz, P	1
Andersen, GL; DeSantis, TZ; Pahl, M; Piceno, YM; Vaziri, ND; Wong, J	1
Barnes, KJ; Miners, JO; Polasek, TM; Rowland, A	1
Chen, YH; Hsieh, YT; Lee, CC; Lee, JH; Sun, CY; Wu, MS; Wu, VC; Young, GH	1
Banerjee, T; Hostetter, TH; Melamed, M; Meyer, TW; Powe, NR; Shafi, T; Zhu, Y	1
Beelen, RHJ; Hordijk, PL; van Bezu, J; Vervloet, MG; Vila Cuenca, M	1
Adkins, NS; Bartlett, DE; Bown, PC; Cottrill, CL; D Pratt, R; Khanal, T; Klug, RL; Lakhani, HV; Miller, RB; Nease, DB; Shapiro, JI; Sodhi, K; Thiesfeldt, S	1
Chen, P; Fang, JT; Hsiao, YS; Huang, CH; Juang, RS; Liu, ZW; Sahoo, S; Yen, SC	1
Cho, SB; Kim, CH; Kim, SJ; Moon, SJ; Park, HC; Zhang, X	1
Anansilp, K; Kamprom, W; Mas-Oodi, S; Rattanasompattikul, M; Supokawej, A; Tawonsawatruk, T	1
Aljama, P; Carmona, A; Guerrero, F; Jimenez, MJ; Martín-Malo, A; Moreno, JA; Obrero, T; Pulido, V; Soriano, S	1
Bohorquez, L; Calle, Y; Calleros, L; Campillo, S; de Frutos, S; García-Ayuso, D; Griera, M; Gutiérrez-Calabrés, E; Miguel, V; Rodríguez-Puyol, D; Rodríguez-Puyol, M	1
Asgharian, M; Ghojazadeh, M; Gholizadeh, P; Jouyban, A; Samadi Kafil, H; Samadi, A; Soleymani, J; Tayebi Khosroshahi, H	1
Barreiros, L; Campagnolo, S; Fernandes, SR; Marques, SS; Sampaio-Maia, B; Segundo, MA; Silva, LAP	1
Aliasgharzadeh, A; Jouyban, A; Moradi, M; Oladi-Ghadikolaei, R; Shayanfar, A; Soleymani, J; Tayebi Khosroshahi, H	1
Abate, M; Capasso, A; Capasso, G; Caraglia, M; De, A; Di Paola, R; Izhar, R; La Russa, A; Perna, AF; Simeoni, M; Zappavigna, S	1
Arvizu-Hernández, M; Caballero-Islas, AE; Camacho-Colin, D; Correa-Rotter, R; Del Toro-Cisneros, N; Gómez-Correa, LL; Hernandez-Ordoñez, SÓ; Martínez-Rueda, A; Vega-Vega, O	1
Carmona, A; Guerrero, F; Jimenez, MJ; Martin-Malo, A; Muñoz-Castañeda, JR; Rodriguez, M; Soriano, S	1

Reviews

4 review(s) available for indican and 4-cresol

Article	Year
Protein-bound uremic solutes: the forgotten toxins. Kidney international. Supplement, 2001, Volume: 78 Topics: Animals; Cresols; Furans; Hippurates; Homocysteine; Humans; Indican; Intestinal Mucosa; Kinetics; Propionates; Protein Binding; Proteins; Renal Dialysis; Toxins, Biological; Uremia	2001
Protein-bound uremic retention solutes. Advances in renal replacement therapy, 2003, Volume: 10, Issue:4 Topics: Animals; Blood Proteins; Cresols; Furans; Hippurates; Homocysteine; Humans; Indican; Propionates; Renal Dialysis; Uremia	2003
An update on uremic toxins. International urology and nephrology, 2013, Volume: 45, Issue:1 Topics: beta 2-Microglobulin; Biomarkers; Cardiovascular Diseases; Cresols; Dialysis Solutions; Fibroblast Growth Factor-23; Glucuronides; Guanidines; Humans; Indican; Peptides; Protein Binding; Renal Dialysis; Sulfuric Acid Esters; Urea; Uremia	2013
Possible Effects of Uremic Toxins p-Cresol, Indoxyl Sulfate, p-Cresyl Sulfate on the Development and Progression of Colon Cancer in Patients with Chronic Renal Failure. Genes, 2023, 06-13, Volume: 14, Issue:6 Topics: Colonic Neoplasms; Humans; Indican; Inflammation; Kidney Failure, Chronic; Renal Insufficiency, Chronic; Sulfates; Uremic Toxins	2023

Trials

3 trial(s) available for indican and 4-cresol

Article	Year
Elevation of circulating endothelial microparticles in patients with chronic renal failure. Journal of thrombosis and haemostasis : JTH, 2006, Volume: 4, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Annexin A5; Antigens, CD; Cadherins; CD146 Antigen; Cells, Cultured; Cresols; Endothelial Cells; Female; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Particle Size; Renal Dialysis; Toxins, Biological; Uremia	2006
Free and total p-cresol sulfate levels and infectious hospitalizations in hemodialysis patients in CHOICE and HEMO. Medicine, 2017, Volume: 96, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Cresols; Female; Gastrointestinal Diseases; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Patient Admission; Sepsis; Young Adult	2017
Improved β2-Microglobulin and Phosphorous Removal with Expanded Hemodialysis and Online Hemodiafiltration versus High-Flux Hemodialysis: A Cross-Over Randomized Clinical Trial. Blood purification, 2023, Volume: 52, Issue:7-8 Topics: beta 2-Microglobulin; Cross-Over Studies; Hemodiafiltration; Humans; Indican; Interleukin-10; Interleukin-6; Kidney Failure, Chronic; Phosphates; Phosphorus; Prospective Studies; Renal Dialysis; Serum Albumin	2023

Other Studies

26 other study(ies) available for indican and 4-cresol

Article	Year
The effect of saccharin ingestion on the excretion of microbial amino acid metabolites in rat and man. Toxicology and applied pharmacology, 1987, Volume: 91, Issue:3 Topics: Amino Acids; Animals; Bacteria; Body Weight; Cresols; Dose-Response Relationship, Drug; Drinking; Eating; Humans; Indican; Male; Phenol; Phenols; Rats; Rats, Inbred Strains; Saccharin; Time Factors	1987
Microbial amino acid metabolites and bladder cancer: no evidence of promoting activity in man. Human toxicology, 1988, Volume: 7, Issue:3 Topics: Aged; Aged, 80 and over; Carcinogens; Carcinoma, Transitional Cell; Cocarcinogenesis; Cresols; Female; Humans; Indican; Male; Middle Aged; Phenol; Phenols; Urinary Bladder Neoplasms	1988
Biochemical activity of intestinal microflora in adult coeliac disease. Die Nahrung, 1984, Volume: 28, Issue:6-7 Topics: Adolescent; Adult; Bacteria; Celiac Disease; Cresols; Diet; Female; Humans; Indican; Intestinal Mucosa; Intestines; Male; Middle Aged; Phenols	1984
Inhibition of the accumulation of uremic toxins in the blood and their precursors in the feces after oral administration of Lebenin, a lactic acid bacteria preparation, to uremic patients undergoing hemodialysis. Nephron, 1996, Volume: 74, Issue:2 Topics: Administration, Oral; Adult; Bacteria, Aerobic; Bacteria, Anaerobic; Bifidobacterium; Capsules; Cresols; Enterococcus faecalis; Feces; Female; Humans; Indican; Lactobacillus acidophilus; Male; Middle Aged; Phenol; Phenols; Renal Dialysis; Uremia	1996
Intradialytic removal of protein-bound uraemic toxins: role of solute characteristics and of dialyser membrane. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:1 Topics: Aged; Aged, 80 and over; Creatinine; Cresols; Female; Furans; Hippurates; Humans; Indican; Kidneys, Artificial; Male; Membranes, Artificial; Middle Aged; Propionates; Protein Binding; Renal Dialysis; Toxins, Biological; Urea; Uremia	2000
The uremic solutes p-cresol and indoxyl sulfate inhibit endothelial proliferation and wound repair. Kidney international, 2004, Volume: 65, Issue:2 Topics: Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Cresols; Endothelium, Vascular; Humans; Indican; Umbilical Veins; Uremia; Wound Healing	2004
Increasing the clearance of protein-bound solutes by addition of a sorbent to the dialysate. Journal of the American Society of Nephrology : JASN, 2007, Volume: 18, Issue:3 Topics: Charcoal; Cresols; Dialysis Solutions; Humans; Indican; Models, Biological; Protein Binding; Proteins; Renal Dialysis; Sulfuric Acid Esters; Urea	2007
Serum protein-bound uraemic toxins and clinical outcomes in haemodialysis patients. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Blood Proteins; C-Reactive Protein; Cresols; Female; Humans; Indican; Logistic Models; Male; Middle Aged; Prospective Studies; Renal Dialysis; Renal Plasma Flow	2010
Inhibitory effects of uraemic toxins 3-indoxyl sulfate and p-cresol on losartan metabolism in vitro. The Journal of pharmacy and pharmacology, 2010, Volume: 62, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Aryl Hydrocarbon Hydroxylases; Cresols; Cytochrome P-450 CYP2C9; Humans; Imidazoles; In Vitro Techniques; Indican; Kidney Failure, Chronic; Losartan; Microsomes, Liver; Renal Dialysis; Tetrazoles; Uremia	2010
Serum total p-cresol and indoxyl sulfate correlated with stage of chronic kidney disease in renal transplant recipients. Transplantation proceedings, 2012, Volume: 44, Issue:3 Topics: Adult; Cresols; Disease Progression; Female; Humans; Indican; Kidney Failure, Chronic; Kidney Transplantation; Male	2012
Prominent accumulation in hemodialysis patients of solutes normally cleared by tubular secretion. Journal of the American Society of Nephrology : JASN, 2014, Volume: 25, Issue:3 Topics: Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Cresols; Female; Glutamine; Hippurates; Humans; Indican; Kidney Failure, Chronic; Kidney Tubules; Male; Middle Aged; Models, Statistical; Renal Dialysis	2014
Uremic toxins impair human bone marrow-derived mesenchymal stem cells functionality in vitro. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2014, Volume: 66, Issue:4 Topics: Apoptosis; Cell Adhesion; Cell Membrane; Cell Proliferation; Cell Survival; Cells, Cultured; Cresols; Humans; Indican; Mesenchymal Stem Cells; Uremia	2014
Expansion of urease- and uricase-containing, indole- and p-cresol-forming and contraction of short-chain fatty acid-producing intestinal microbiota in ESRD. American journal of nephrology, 2014, Volume: 39, Issue:3 Topics: Adult; Aged; Ammonia; Cresols; Diet; Fatty Acids, Volatile; Female; Humans; Indican; Indoles; Inflammation; Intestines; Kidney Failure, Chronic; Male; Microbiota; Middle Aged; Sulfuric Acid Esters; Urate Oxidase; Urea; Urease	2014
Inhibition of human drug-metabolising cytochrome P450 and UDP-glucuronosyltransferase enzyme activities in vitro by uremic toxins. European journal of clinical pharmacology, 2014, Volume: 70, Issue:9 Topics: Benzyl Alcohol; Cresols; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Glucuronosyltransferase; Hippurates; Humans; Indican; Microsomes, Liver; Toxins, Biological; Uremia	2014
Protein-bound uremic toxins induce tissue remodeling by targeting the EGF receptor. Journal of the American Society of Nephrology : JASN, 2015, Volume: 26, Issue:2 Topics: Animals; Cells, Cultured; Cresols; ErbB Receptors; Humans; In Vitro Techniques; Indican; Injections, Intraperitoneal; Kidney; Kidney Tubules, Proximal; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred Strains; Models, Animal; Nephrectomy; Signal Transduction; Toxins, Biological	2015
Stabilization of cell-cell junctions by active vitamin D ameliorates uraemia-induced loss of human endothelial barrier function. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2019, 02-01, Volume: 34, Issue:2 Topics: Actins; Adult; Aged; Antigens, CD; Cadherins; Cell Adhesion; Cell Movement; Cells, Cultured; Cresols; Endothelial Cells; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Indican; Intercellular Junctions; Male; Middle Aged; Thrombin; Uremia; Vitamin D; Young Adult	2019
Uremic Toxins Activates Na/K-ATPase Oxidant Amplification Loop Causing Phenotypic Changes in Adipocytes in In Vitro Models. International journal of molecular sciences, 2018, Sep-10, Volume: 19, Issue:9 Topics: 3T3-L1 Cells; Adipocytes; Animals; Biomarkers; Cell Proliferation; Cell Survival; Cells, Cultured; Cresols; Humans; Indican; Mesenchymal Stem Cells; Mice; Oxidants; Oxidative Stress; Peptide Fragments; Renal Insufficiency, Chronic; Sodium-Potassium-Exchanging ATPase	2018
Carbon Nanotube/Conducting Polymer Hybrid Nanofibers as Novel Organic Bioelectronic Interfaces for Efficient Removal of Protein-Bound Uremic Toxins. ACS applied materials & interfaces, 2019, Nov-27, Volume: 11, Issue:47 Topics: Adsorption; Cresols; Electronics; Hippurates; Humans; Indican; Nanotubes, Carbon; Polymers; Proteins; Renal Dialysis; Toxins, Biological; Uremia	2019
Uremic solutes of indoxyl sulfate and Human & experimental toxicology, 2021, Volume: 40, Issue:1 Topics: Animals; Cells, Cultured; Cresols; Humans; Indican; Keratinocytes; Male; Mice; Receptor, PAR-2; Up-Regulation	2021
P International journal of medical sciences, 2021, Volume: 18, Issue:3 Topics: Cells, Cultured; Cellular Senescence; Chronic Kidney Disease-Mineral and Bone Disorder; Cresols; Healthy Volunteers; Humans; Indican; Mesenchymal Stem Cells; Osteogenesis; Primary Cell Culture; Renal Insufficiency, Chronic; Toxins, Biological; Uremia	2021
Passage Number-Induced Replicative Senescence Modulates the Endothelial Cell Response to Protein-Bound Uremic Toxins. Toxins, 2021, 10-19, Volume: 13, Issue:10 Topics: Aging; Cell Movement; Cellular Senescence; Cresols; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; Indican; Renal Insufficiency, Chronic	2021
Indoxyl sulfate- and P-cresol-induced monocyte adhesion and migration is mediated by integrin-linked kinase-dependent podosome formation. Experimental & molecular medicine, 2022, Volume: 54, Issue:3 Topics: Animals; Cell Adhesion; Cresols; Cytoskeletal Proteins; Humans; Indican; Mice; Monocytes; Podosomes; Protein Serine-Threonine Kinases; THP-1 Cells	2022
Correlation of inflammatory biomarkers with the diversity of Bacteroidaceae, Bifidobacteriaceae, Prevotellaceae and Lactobacillaceae families in the intestinal microbiota of patients with end stage renal disease. Advances in medical sciences, 2022, Volume: 67, Issue:2 Topics: Antioxidants; Bacteroidaceae; Biomarkers; Gastrointestinal Microbiome; Humans; Indican; Interleukin-1; Interleukin-6; Kidney Failure, Chronic; Lactobacillaceae; RNA, Ribosomal, 16S; Tumor Necrosis Factor-alpha	2022
Rapid and sustainable HPLC method for the determination of uremic toxins in human plasma samples. Analytical and bioanalytical chemistry, 2023, Volume: 415, Issue:4 Topics: Chromatography, High Pressure Liquid; Cresols; Humans; Indican; Phenol; Renal Insufficiency, Chronic; Toxins, Biological; Uremic Toxins	2023
Serum Levels of Indoxyl Sulfate and P-cresol in Type II Diabetic Patients With and Without Nephropathy. Iranian journal of kidney diseases, 2023, Volume: 17, Issue:3 Topics: Creatinine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Indican; Proteinuria; Uric Acid	2023
Uremic Toxins Induce THP-1 Monocyte Endothelial Adhesion and Migration through Specific miRNA Expression. International journal of molecular sciences, 2023, Aug-18, Volume: 24, Issue:16 Topics: Atherosclerosis; Endothelial Cells; Humans; Indican; MicroRNAs; Monocytes; NF-kappa B; Tissue Adhesions; Uremic Toxins	2023