indazoles has been researched along with way 252623 in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 10 (76.92) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Basso, MD; Berrodin, TJ; Clerin, V; DiBlasio-Smith, E; Evans, MJ; Feingold, I; Gardell, SJ; Halpern, AR; Hartman, HB; Keith, JC; LaVallie, ER; Mounts, WM; Nambi, P; Quinet, EM; Resmini, C; Steffan, RJ; Vlasuk, GP; Wrobel, J; Yates, DW; Zhong, W | 1 |
| Ratni, H; Wright, MB | 1 |
| Alique, M; Badimon, JJ; Cimmino, G; Connolly, TM; Feuerstein, G; Fuster, V; Giannarelli, C; Ibanez, B; Ruiz, JM; Zafar, MU | 1 |
| Armando, AM; Bi, J; Cahill, GL; Cavenee, WK; Cloughesy, TF; Cravatt, BF; Furnari, FB; Gahman, TC; Gu, Y; Hon, GC; Hong, C; Hulce, JJ; Ikegami, S; Jenkins, D; Liu, F; Lum, KM; Martini, M; Masui, K; Mischel, PS; Quehenberger, O; Rong, X; Shiau, AK; Tontonoz, P; Turner, KM; Villa, GR; Yang, H; Zanca, C | 1 |
| Fang, Y; Ji, WD; Wang, JZ; Xu, H | 1 |
| Chen, H; Cheng, J; Duan, J; He, H; Hua, R; Jiang, X; Li, Q; Xu, D; Yang, L | 1 |
| Cao, E; Hu, L; Lindfors, L; Lindgren, A; Martinsson, S; Michaëlsson, E; Porter, CJH; Sigfridsson, K; Skantze, U; Trevaskis, NL | 1 |
| Cheng, Y; Hou, Y; Pu, X; Wan, W; Wang, K; Ye, X | 1 |
| Li, J; Qi, G; Wang, Q; Wu, G; Xia, Q; Xu, Y; Zhang, H | 1 |
| Fikrig, E; Hwang, J; Wang, Y | 1 |
| Bianchetti, E; Canoll, P; Ishida, CT; Karpel-Massler, G; Kleiner, G; Nguyen, TTT; Quinzii, CM; Sanchez-Quintero, MJ; Shang, E; Shu, C; Siegelin, MD; Torrini, C; Westhoff, MA; Zhang, Y | 1 |
| Gao, L; Hu, H; Wu, D; Yan, Z; Young, JAT; Zeng, J | 1 |
| Best, SM; Bloom, ME; Carmody, A; Chiramel, AI; Dorward, DW; Mlera, L; Offerdahl, DK | 1 |
1 review(s) available for indazoles and way 252623
| Article | Year |
|---|---|
Recent progress in liver X receptor-selective modulators.
Topics: Animals; Benzoates; Benzylamines; Humans; Hydrocarbons, Fluorinated; Indazoles; Ligands; Liver; Liver X Receptors; Orphan Nuclear Receptors; Protein Binding; Sulfonamides | 2010 |
12 other study(ies) available for indazoles and way 252623
| Article | Year |
|---|---|
LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse.
Topics: Animals; Atherosclerosis; Caco-2 Cells; Cholesterol, LDL; Cricetinae; Disease Models, Animal; Humans; Indazoles; Ligands; Lipid Metabolism; Liver; Liver X Receptors; Macaca fascicularis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orphan Nuclear Receptors | 2009 |
Synergistic effect of liver X receptor activation and simvastatin on plaque regression and stabilization: an magnetic resonance imaging study in a model of advanced atherosclerosis.
Topics: Animals; Anticholesteremic Agents; Aorta, Abdominal; Aortic Diseases; Atherosclerosis; Chemokine CCL2; Cyclooxygenase 2; Disease Progression; Drug Combinations; Drug Synergism; Indazoles; Liver X Receptors; Magnetic Resonance Angiography; Orphan Nuclear Receptors; Plaque, Atherosclerotic; Rabbits; Random Allocation; Simvastatin; Thromboplastin; Up-Regulation | 2012 |
An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cholesterol; Female; Glioblastoma; Humans; Indazoles; Liver X Receptors; Mice; Treatment Outcome | 2016 |
LXR agonists promote the proliferation of neural progenitor cells through MEK-ERK pathway.
Topics: Animals; Benzoates; Benzylamines; Cell Proliferation; Cells, Cultured; Flavonoids; Gene Expression; Indazoles; Liver X Receptors; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice, Inbred C57BL; Mice, Knockout; Neural Stem Cells; Protein Kinase Inhibitors | 2017 |
SIRT2 plays a novel role on progesterone, estradiol and testosterone synthesis via PPARs/LXRα pathways in bovine ovarian granular cells.
Topics: Acetamides; Animals; Cattle; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Estradiol; Female; Granulosa Cells; Indazoles; Liver X Receptors; Oocytes; Peroxisome Proliferator-Activated Receptors; Progesterone; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirtuin 2; Steroid 17-alpha-Hydroxylase; Testosterone; Theca Cells; Thiazoles | 2019 |
Promoting intestinal lymphatic transport targets a liver-X receptor (LXR) agonist (WAY-252,623) to lymphocytes and enhances immunomodulation.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter 1; Female; Forkhead Transcription Factors; Gene Expression; Immunomodulation; Indazoles; Intestines; Liver X Receptors; Lymphatic Vessels; Lymphocytes; Male; Nanoparticles; Rats, Inbred Lew; Rats, Sprague-Dawley; T-Lymphocytes, Regulatory | 2019 |
The LXR-623-induced long non-coding RNA LINC01125 suppresses the proliferation of breast cancer cells via PTEN/AKT/p53 signaling pathway.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Humans; Indazoles; Mice; Mice, Inbred BALB C; Mice, Nude; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; PTEN Phosphohydrolase; RNA, Long Noncoding; Signal Transduction; Transplantation, Heterologous; Tumor Suppressor Protein p53; Up-Regulation | 2019 |
Targeting the transcription factor receptor LXR to treat clear cell renal cell carcinoma: agonist or inverse agonist?
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter 1; Carcinoma, Renal Cell; Cell Proliferation; Cell Survival; Cholesterol; Drug Inverse Agonism; Fatty Acids; Humans; Indazoles; Kidney Neoplasms; Lipid Metabolism; Liver X Receptors; Mice; Mice, Nude; Receptors, LDL; Sulfonamides; Transplantation, Heterologous | 2019 |
Inhibition of Chikungunya Virus Replication in Primary Human Fibroblasts by Liver X Receptor Agonist.
Topics: Antiviral Agents; Apolipoproteins E; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; Chikungunya virus; Cholesterol; Fibroblasts; Gene Expression Regulation; Host-Pathogen Interactions; Humans; Indazoles; Interferons; Liver X Receptors; Primary Cell Culture; RNA, Small Interfering; Signal Transduction; Virus Replication | 2019 |
Activation of LXRβ inhibits tumor respiration and is synthetically lethal with Bcl-xL inhibition.
Topics: Animals; Apoptosis; bcl-X Protein; Benzoates; Benzylamines; Carcinoma; Cell Proliferation; Cell Respiration; Disease Models, Animal; Gene Expression Profiling; Glioblastoma; Humans; Indazoles; Liver X Receptors; Melanoma; Metabolomics; Models, Theoretical; Treatment Outcome | 2019 |
Activation of the Liver X Receptor Pathway Inhibits HBV Replication in Primary Human Hepatocytes.
Topics: Antigens, Viral; Antiviral Agents; Benzoates; Benzylamines; Cells, Cultured; Cholesterol 7-alpha-Hydroxylase; DNA, Viral; Drug Evaluation, Preclinical; Gene Knockdown Techniques; Hepatitis B; Hepatitis B virus; Hepatocytes; Heterocyclic Compounds, 4 or More Rings; Humans; Hydrocarbons, Fluorinated; Indazoles; Liver; Liver X Receptors; Primary Cell Culture; RNA, Viral; Signal Transduction; Sulfonamides; Virus Replication | 2020 |
The liver X receptor agonist LXR 623 restricts flavivirus replication.
Topics: Antiviral Agents; Cell Line, Tumor; Cell Proliferation; Cytokines; Cytopathogenic Effect, Viral; Cytoplasmic Vesicles; Encephalitis Viruses, Tick-Borne; Endoplasmic Reticulum; Humans; Indazoles; Liver X Receptors; Virus Replication; Zika Virus | 2021 |