Page last updated: 2024-08-21

indazoles and transferrin

indazoles has been researched along with transferrin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's9 (75.00)29.6817
2010's1 (8.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Hartmann, M; Keppler, B; Kratz, F; Messori, L1
Hartinger, CG; Keppler, BK; Rudnev, AV; Semenova, O; Timerbaev, AR1
Groessl, M; Hann, S; Hartinger, CG; Keppler, BK; Koellensperger, G; Rudnev, AV; Stingeder, G; Sulyok, M; Timerbaev, AR1
Arion, VB; Eichinger, A; Graf von Keyserlingk, N; Jakupec, MA; Kapitza, S; Keppler, BK; Marian, B; Pongratz, M; Reisner, E1
Abramski, JK; Hartinger, CG; Jarosz, M; Keppler, BK; Polec-Pawlak, K; Semenova, O; Timerbaev, AR1
Hartinger, CG; Jakupec, MA; Keppler, BK; Kynast, B; Zorbas, H; Zorbas-Seifried, S1
Abramski, JK; Foteeva, LS; Hartinger, CG; Jarosz, M; Keppler, BK; Połeć-Pawlak, K; Rudnev, AV; Timerbaev, AR1
Abramski, JK; Ferenc, J; Foteeva, LS; Jarosz, M; Keppler, BK; Połeć-Pawlak, K; Timerbaev, AR1
Groessl, M; Hartinger, CG; Jarosz, M; Keppler, BK; Polec-Pawlak, K1
Alex, D; Drescher, A; Grubert, M; Henke, MM; Hilger, RA; Jaehde, U; Richly, H; Scheulen, ME; Thyssen, D1
Jarosz, M; Matczuk, M; Pawlak, K; Timerbaev, AR1
Chetcuti, ARM; Lay, PA; Levina, A1

Reviews

1 review(s) available for indazoles and transferrin

ArticleYear
From bench to bedside--preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A).
    Journal of inorganic biochemistry, 2006, Volume: 100, Issue:5-6

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; DNA; Humans; Indazoles; Models, Molecular; Organometallic Compounds; Ruthenium Compounds; Transferrin

2006

Trials

1 trial(s) available for indazoles and transferrin

ArticleYear
Capillary electrophoresis hyphenated to inductively coupled plasma-mass spectrometry: a novel approach for the analysis of anticancer metallodrugs in human serum and plasma.
    Electrophoresis, 2008, Volume: 29, Issue:10

    Topics: Antineoplastic Agents; Blood Chemical Analysis; Blood Proteins; Electrophoresis, Capillary; Humans; In Vitro Techniques; Indazoles; Mass Spectrometry; Neoplasms; Organometallic Compounds; Protein Binding; Ruthenium Compounds; Serum Albumin; Transferrin

2008

Other Studies

10 other study(ies) available for indazoles and transferrin

ArticleYear
The binding properties of two antitumor ruthenium(III) complexes to apotransferrin.
    The Journal of biological chemistry, 1994, Jan-28, Volume: 269, Issue:4

    Topics: Antineoplastic Agents; Apoproteins; Chromatography, High Pressure Liquid; Humans; Imidazoles; Indazoles; Magnetic Resonance Spectroscopy; Molecular Structure; Organometallic Compounds; Protein Binding; Ruthenium; Spectrophotometry; Transferrin

1994
Comparative binding of antitumor indazolium [trans-tetrachlorobis(1H-indazole)ruthenate(III)] to serum transport proteins assayed by capillary zone electrophoresis.
    Analytical biochemistry, 2005, Jun-15, Volume: 341, Issue:2

    Topics: Antineoplastic Agents; Blood Protein Electrophoresis; Electrophoresis, Capillary; Humans; Hydrolysis; Indazoles; Organometallic Compounds; Protein Binding; Ruthenium Compounds; Serum Albumin; Transferrin

2005
Interactions of a novel ruthenium-based anticancer drug (KP1019 or FFC14a) with serum proteins--significance for the patient.
    International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:12

    Topics: Albumins; Antineoplastic Agents; Chromatography, High Pressure Liquid; Electrophoresis, Capillary; Humans; Indazoles; Neoplasms; Organometallic Compounds; Protein Binding; Ruthenium; Ruthenium Compounds; Spectrometry, Mass, Electrospray Ionization; Transferrin

2005
KP1019 (FFC14A) from bench to bedside: preclinical and early clinical development--an overview.
    International journal of clinical pharmacology and therapeutics, 2005, Volume: 43, Issue:12

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Clinical Trials, Phase I as Topic; Drug Evaluation, Preclinical; Humans; Indazoles; Organometallic Compounds; Oxidation-Reduction; Ruthenium Compounds; Transferrin

2005
Platinum group metallodrug-protein binding studies by capillary electrophoresis - inductively coupled plasma-mass spectrometry: a further insight into the reactivity of a novel antitumor ruthenium(III) complex toward human serum proteins.
    Electrophoresis, 2006, Volume: 27, Issue:5-6

    Topics: Antineoplastic Agents; Binding, Competitive; Blood Proteins; Electrophoresis, Capillary; Humans; In Vitro Techniques; Indazoles; Kinetics; Mass Spectrometry; Organometallic Compounds; Platinum; Protein Binding; Ruthenium Compounds; Serum Albumin; Transferrin

2006
Probing the stability of serum protein-ruthenium(III) drug adducts in the presence of extracellular reductants using CE.
    Electrophoresis, 2007, Volume: 28, Issue:13

    Topics: Ascorbic Acid; Blood Proteins; Buffers; Drug Stability; Electrolytes; Electrophoresis, Capillary; Glutathione; Indazoles; Mass Spectrometry; Organometallic Compounds; Oxidation-Reduction; Ruthenium Compounds; Serum Albumin; Spectrophotometry, Ultraviolet; Transferrin

2007
Application of capillary electrophoresis-inductively coupled plasma mass spectrometry to comparative studying of the reactivity of antitumor ruthenium(III) complexes differing in the nature of counter-ion toward human serum proteins.
    Journal of chromatography. A, 2008, May-30, Volume: 1192, Issue:2

    Topics: Algorithms; Antineoplastic Agents; Blood Proteins; Capillary Electrochromatography; Humans; Indazoles; Indicators and Reagents; Kinetics; Mass Spectrometry; Organometallic Compounds; Ruthenium Compounds; Serum Albumin; Solutions; Transferrin

2008
Pharmacokinetic study of sodium trans[tetrachlorobis(1H-indazole)-ruthenate (III)]/-indazole hydrochloride (1:1.1) (FFC14A) in patients with solid tumors.
    International journal of clinical pharmacology and therapeutics, 2009, Volume: 47, Issue:1

    Topics: Antineoplastic Agents; Biomarkers; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; DNA Adducts; Dose-Response Relationship, Drug; Half-Life; Humans; Indazoles; Infusions, Intravenous; Leukocytes; Metabolic Clearance Rate; Neoplasms; Organometallic Compounds; Ruthenium Compounds; Serum Albumin; Transferrin

2009
Molecular mass spectrometry in metallodrug development: a case of mapping transferrin-mediated transformations for a ruthenium(III) anticancer drug.
    Analytica chimica acta, 2014, Dec-03, Volume: 851

    Topics: Antineoplastic Agents; Biological Transport; Biotransformation; Coordination Complexes; Drug Discovery; Indazoles; Models, Molecular; Molecular Weight; Organometallic Compounds; Protein Conformation; Ruthenium; Spectrometry, Mass, Electrospray Ionization; Transferrin

2014
Controversial Role of Transferrin in the Transport of Ruthenium Anticancer Drugs.
    Biomolecules, 2022, 09-18, Volume: 12, Issue:9

    Topics: Antineoplastic Agents; Ferric Compounds; Humans; Indazoles; Organometallic Compounds; Receptors, Transferrin; Ruthenium; Ruthenium Compounds; Serum Albumin; Transferrin

2022