indazoles has been researched along with thiophenes in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 11 (57.89) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Atienza, J; Claramunt, RM; Elguero, J; Escario, JA; Gómez Barrio, A; Mester, B | 1 |
| Ali, A; Balkovec, JM; Carballo-Jane, E; Einstein, M; Forrest, MJ; Ge, L; Graham, DW; Hammond, ML; Harris, G; Kelly, TM; Luell, S; Mazur, P; Miller, DK; Pandit, S; Quraishi, N; Santoro, J; Sitlani, A; Tata, JR; Thompson, CF; Thompson, CM; Wang, C; Williamson, J; Zaller, DM | 1 |
| Aimone, L; Albom, M; Angeles, T; Chang, H; Hudkins, RL; Hunter, K; Josef, K; Robinson, C; Ruggeri, B; Underiner, TL; Weinberg, L; Yang, S; Zulli, A | 1 |
| Albert, DH; Banfor, PN; Cox, BF; Davidsen, SK; Franklin, PH; Fryer, RM; Gintant, GA; Larson, KJ; Noonan, WT; Segreti, JA; Tapang, P; Widomski, DL | 1 |
| Alix, S; Box, G; Chuckowree, I; Clarke, PA; De Haven Brandon, A; Di Stefano, F; Eccles, SA; Folkes, A; Gowan, S; Hayes, A; Henley, AT; Lensun, L; McDonald, E; Patel, S; Pergl-Wilson, G; Raynaud, FI; Robson, A; Saghir, N; Sheldrake, P; Shuttleworth, S; Valenti, M; Wan, NC; Workman, P; Zhyvoloup, A | 1 |
| Basten, S; Campbell, RA; Cumming, IA; Gillen, KJ; Gillespie, J; Jamieson, C; Kazemier, B; Kiczun, M; Lamont, Y; Lyons, AJ; Maclean, JK; Moir, EM; Morrow, JA; Papakosta, M; Rankovic, Z; Smith, L | 1 |
| Alcantara, SL; Brzozowski, MJ; Iravani, MM; Jenner, P; Rose, S | 1 |
| Raynaud, FI; Workman, P | 1 |
| Gasperi, T; Loreto, MA; Migliorini, A; Oliviero, C | 1 |
| Lazzari, P; Mastinu, A; Pani, L; Pinna, GA; Pira, M | 1 |
| Beall, HD; Bibby, JM; Hassani, M; Moody, CJ; Newsome, JJ; Swann, E | 1 |
| Inamoto, K | 1 |
| Alicke, B; Barck, K; Carano, RA; Nishimura, M; Olivero, AG; Pang, J; Phillips, HS; Quiason, C; Salphati, L; Shahidi-Latham, S | 1 |
| Hao, Y; Tang, J; Wang, K | 1 |
| Cheng, Y; Gao, G; Lan, J; Li, G; Liu, Y; Shi, Y; Wu, D; You, J | 1 |
| Berg, JD; Ford, LT | 1 |
| Appolonova, S; Arfè, R; Bertolucci, C; Bilel, S; Fantinati, A; Frisoni, P; Grignolio, S; Marti, M; Morbiato, E; Neri, M; Savchuk, S; Tagliaro, F; Tirri, M | 1 |
| Gabrail, N; Smith, C | 1 |
| Cao, Y; Guo, B; Kong, D; Lu, Z; Meng, X; Yang, Y; Zhang, D | 1 |
1 review(s) available for indazoles and thiophenes
| Article | Year |
|---|---|
Synthesis of heterocyclic compounds through palladium-catalyzed C-H cyclization processes.
Topics: Benzothiazoles; Carbon; Catalysis; Cyclization; Heterocyclic Compounds; Hydrogen; Indazoles; Indoles; Palladium; Quinolones; Thiophenes | 2013 |
18 other study(ies) available for indazoles and thiophenes
| Article | Year |
|---|---|
Research for new antichagasic drugs.
Topics: Animals; Azoles; Benzimidazoles; Chagas Disease; Imidazoles; Indazoles; Indoles; Mice; Nifurtimox; Nitro Compounds; Thiophenes; Triazoles; Trypanocidal Agents; Trypanosoma cruzi | 1991 |
Novel N-arylpyrazolo[3,2-c]-based ligands for the glucocorticoid receptor: receptor binding and in vivo activity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Crystallography, X-Ray; Enzyme Induction; Female; Glutamate-Ammonia Ligase; Humans; Indazoles; Interleukin-6; Ligands; Mice; Mice, Inbred BALB C; Molecular Conformation; Protein Isoforms; Pyrazoles; Radioligand Assay; Receptors, Glucocorticoid; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Transcription, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha; Tyrosine Transaminase | 2004 |
TIE-2/VEGF-R2 SAR and in vitro activity of C3-acyl dihydroindazolo[5,4-a]pyrrolo[3,4-c]carbazole analogs.
Topics: Acylation; Angiogenesis Inhibitors; Angiotensin I; Animals; Aorta; Biological Availability; Cells, Cultured; Chemotaxis; Endothelial Cells; Enzyme Inhibitors; Indazoles; Indoles; Models, Chemical; Rats; Receptor, TIE-2; Structure-Activity Relationship; Thiophenes; Umbilical Veins; Vascular Endothelial Growth Factor Receptor-2 | 2008 |
Effect of the multitargeted receptor tyrosine kinase inhibitor, ABT-869 [N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea], on blood pressure in conscious rats and mice: reversal with antihypertensive agents and effect on tumor growt
Topics: Acrylates; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enalapril; Humans; Imidazoles; Indazoles; Lisinopril; Male; Mice; Mice, SCID; Neoplasms; Nifedipine; Phenylurea Compounds; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Ramipril; Rats; Rats, Sprague-Dawley; Telmisartan; Thiophenes; Xenograft Model Antitumor Assays | 2009 |
Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941.
Topics: Administration, Oral; Animals; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Female; Furans; Glioblastoma; Humans; Indazoles; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Structure; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinases; Pyridines; Pyrimidines; Sulfonamides; Thiophenes; TOR Serine-Threonine Kinases; Umbilical Veins; Xenograft Model Antitumor Assays | 2009 |
A novel series of positive modulators of the AMPA receptor: discovery and structure based hit-to-lead studies.
Topics: Allosteric Regulation; Animals; Binding Sites; Crystallography, X-Ray; Drug Design; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Humans; Indazoles; Microsomes; Protein Structure, Tertiary; Rats; Receptors, AMPA; Thiophenes | 2010 |
The effect of nNOS inhibitors on toxin-induced cell death in dopaminergic cell lines depends on the extent of enzyme expression.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amidines; Animals; Asparagine; Caspase 3; Cell Death; Cell Line, Tumor; Citrulline; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indazoles; L-Lactate Dehydrogenase; Leupeptins; Mice; Neuroblastoma; Neurotoxins; Nitric Oxide Synthase Type I; Thiophenes; Transfection; Tritium; Tyrosine 3-Monooxygenase; Vesicular Monoamine Transport Proteins | 2011 |
Discovering and developing PI3 kinase inhibitors for cancer: rapid progress through academic-biotech-pharma interactions.
Topics: Animals; Enzyme Inhibitors; Female; Furans; Glioblastoma; Humans; Indazoles; Ovarian Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Pyrimidines; Sulfonamides; Thiophenes | 2011 |
The Suzuki reaction applied to the synthesis of novel pyrrolyl and thiophenyl indazoles.
Topics: Catalysis; Indazoles; Pyrroles; Thiophenes | 2012 |
NESS038C6, a novel selective CB1 antagonist agent with anti-obesity activity and improved molecular profile.
Topics: Analysis of Variance; Animals; Anti-Obesity Agents; Blood Glucose; Body Mass Index; Body Weight; Brain-Derived Neurotrophic Factor; Cannabinoid Receptor Antagonists; Cholesterol; Dietary Fats; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypothalamus; Indazoles; Intra-Abdominal Fat; Liver; Male; Mice; Mice, Inbred C57BL; Nerve Growth Factor; Obesity; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Serotonin Plasma Membrane Transport Proteins; Thiophenes; Transaminases; Triglycerides | 2012 |
Benzofuran-, benzothiophene-, indazole- and benzisoxazole-quinones: excellent substrates for NAD(P)H:quinone oxidoreductase 1.
Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Enzyme Assays; Humans; Indazoles; NAD(P)H Dehydrogenase (Quinone); Oxazoles; Oxidation-Reduction; Quinones; Thiophenes | 2013 |
Distribution of the phosphatidylinositol 3-kinase inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 intracranial glioblastoma models-assessment by matrix-assisted laser desorption ionization imaging.
Topics: Animals; Brain Neoplasms; Enzyme Inhibitors; Female; Glioblastoma; Humans; Indazoles; Mice; Mice, Nude; Phosphoinositide-3 Kinase Inhibitors; Pyrimidines; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfonamides; Thiophenes; Tissue Distribution | 2014 |
Development of Automated Patch Clamp Assay for Evaluation of α7 Nicotinic Acetylcholine Receptor Agonists in Automated QPatch-16.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Automation; Bridged Bicyclo Compounds; Humans; Indazoles; Isoxazoles; Nicotinic Agonists; Patch-Clamp Techniques; Phenylurea Compounds; Quinuclidines; Rats; Thiophenes; Tumor Cells, Cultured | 2015 |
Unparalleled Ease of Access to a Library of Biheteroaryl Fluorophores via Oxidative Cross-Coupling Reactions: Discovery of Photostable NIR Probe for Mitochondria.
Topics: Fluorescent Dyes; Hep G2 Cells; Humans; Indazoles; Luminescent Measurements; Microscopy, Confocal; Mitochondria, Liver; Oxidation-Reduction; Thiophenes | 2016 |
Analysis of legal high materials by ultra-performance liquid chromatography with time of flight mass spectrometry as part of a toxicology vigilance system: what are the most popular novel psychoactive substances in the UK?
Topics: Adamantane; Chromatography, High Pressure Liquid; Humans; Illicit Drugs; Indazoles; Liquid-Liquid Extraction; Methamphetamine; Methylphenidate; Nicotiana; Plants, Medicinal; Powders; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thiophenes | 2017 |
Potential of the zebrafish model for the forensic toxicology screening of NPS: A comparative study of the effects of APINAC and methiopropamine on the behavior of zebrafish larvae and mice.
Topics: Adamantane; Animals; Behavior, Animal; Drug Evaluation, Preclinical; Forensic Toxicology; Indazoles; Male; Methamphetamine; Mice, Inbred ICR; Psychotropic Drugs; Thiophenes; Zebrafish | 2020 |
Avatrombopag Optimizes Response to Niraparib by Managing Thrombocytopenia Associated with Poly-ADP Ribose Polymerase (PARP) Inhibition in Ovarian Cancer and Breast Cancer: A Case Series.
Topics: Adenosine Diphosphate Ribose; Breast Neoplasms; Female; Humans; Indazoles; Ovarian Neoplasms; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Thiazoles; Thiophenes; Thrombocytopenia | 2020 |
Discovery of Thieno[2,3-
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Drug Resistance, Neoplasm; Estrogen Antagonists; Estrogen Receptor alpha; Female; Humans; Indazoles; MCF-7 Cells; Mice; Receptors, Estrogen; Thiophenes | 2022 |