Page last updated: 2024-08-21

indazoles and tamoxifen

indazoles has been researched along with tamoxifen in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's6 (60.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Becker, H; Hoffmann, L; Köllermann, M; Müller, W; Possinger, K; Schlichter, A; Schmoll, E; Stahl, M; Wagner, H; Weidenhammer, W1
Feustel, PJ; Kimelberg, HK; Mongin, AA; Osuka, K; Tranmer, BI1
Andreatini, R; Chioca, LR; Correia, D; Pereira, M; Pizzolatti, MG; Santos, AR; Siba, IP; Vital, MA1
Brennan, KR; Clarke, RB; Gregson, HJ; Harrison, H; Landberg, G; Rogerson, L1
Aguilar, H; Balart, J; Barril, X; Beijersbergen, RL; Bonifaci, N; Bostner, J; Brunet, J; Burnstein, KL; Bustelo, XR; Caizzi, L; Carlson, KE; Clarke, R; Climent, F; Di Croce, L; Esteller, M; Extremera, AI; Figueras, A; Fornander, T; García, N; Garcia-Mata, R; Gil, M; Gómez-Baldó, L; Halonen, P; Islam, A; Jansen, MP; Karlsson, E; Katzenellenbogen, JA; Kiyotani, K; Martrat, G; Mushiroda, T; Nakamura, Y; Nevedomskaya, E; Pérez Tenorio, G; Pujana, MA; Rodríguez-Peña, AB; Rodríguez-Vida, A; Serra-Musach, J; Sgroi, DC; Soler, MT; Stål, O; Urruticoechea, A; Villanueva, A; Vizoso, M; Zembutsu, H; Zwart, W1
Aparicio, AM; Bonnefous, C; Darimont, BD; Douglas, KL; Govek, SP; Grillot, KL; Hager, JH; Joseph, JD; Kahraman, M; Kaufman, JA; Lai, AG; Lee, KJ; Lu, N; Moon, MJ; Nagasawa, JY; Prudente, RY; Rix, PJ; Sensintaffar, J; Smith, ND1
Aparicio, AM; Bonnefous, C; Darimont, BD; Douglas, KL; Govek, SP; Grillot, KL; Hager, JH; Joseph, JD; Julien, JD; Kahraman, M; Kaufman, JA; Lai, AG; Lee, KJ; Lu, N; Moon, MJ; Nagasawa, JY; Prudente, RY; Rix, PJ; Sensintaffar, J; Smith, ND1
Chumakova, A; Esakov, EL; Gullapalli, K; Hale, J; Jensen, J; Lathia, J; Reizes, O; Richards, EG; Torre-Healy, L; Trivedi, D; Wessely, O1
Furugen, A; Iseki, K; Kobayashi, M; Nadai, T; Narumi, K; Saito, Y1
Ala-Hongisto, H; Bertula, K; Elo, LL; Euro, L; Heikkilä, P; Hollmann, B; Hukkinen, K; Ikkala, O; Joensuu, H; Junttila, MR; Kivento, M; Klefström, J; Kovanen, P; Leidenius, M; Martikainen, L; Mattson, J; Meretoja, T; Metcalfe, C; Monni, O; Munne, PM; Mutka, M; Nevalaita, L; Patrikainen, L; Peura, A; Pokki, J; Pouwels, J; Räty, I; Ruuska, J; Sahu, B; Salmela, M; Suomi, T; Väänänen, J; Yavuz, K1

Trials

1 trial(s) available for indazoles and tamoxifen

ArticleYear
Lonidamine versus high-dose tamoxifen in progressive, advanced renal cell carcinoma: results of an ongoing randomized phase II study.
    Seminars in oncology, 1991, Volume: 18, Issue:2 Suppl 4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Drug Evaluation; Female; Humans; Indazoles; Kidney Neoplasms; Male; Middle Aged; Remission Induction; Survival Rate; Tamoxifen; Time Factors

1991

Other Studies

9 other study(ies) available for indazoles and tamoxifen

ArticleYear
Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat.
    Journal of neurochemistry, 2001, Volume: 76, Issue:6

    Topics: Animals; Brain; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Indazoles; Ischemic Attack, Transient; Male; Middle Cerebral Artery; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Sprague-Dawley; Reference Values; Superoxides; Tamoxifen; Tyrosine

2001
Myricitrin, a nitric oxide and protein kinase C inhibitor, exerts antipsychotic-like effects in animal models.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Aug-15, Volume: 35, Issue:7

    Topics: Animals; Antipsychotic Agents; Apomorphine; Arginine; Catalepsy; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Flavonoids; Indazoles; Male; Mice; Motor Activity; Nitric Oxide; Phytotherapy; Plant Leaves; Plant Preparations; Protein Kinase C; Psychotic Disorders; Rats; Rats, Wistar; Stereotyped Behavior; Syzygium; Tamoxifen

2011
Contrasting hypoxic effects on breast cancer stem cell hierarchy is dependent on ER-α status.
    Cancer research, 2013, Feb-15, Volume: 73, Issue:4

    Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Estrogen Antagonists; Estrogen Receptor alpha; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Nude; Neoplastic Stem Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Tamoxifen; Transplantation, Heterologous

2013
VAV3 mediates resistance to breast cancer endocrine therapy.
    Breast cancer research : BCR, 2014, May-28, Volume: 16, Issue:3

    Topics: Androstadienes; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Biomarkers, Tumor; Breast; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Enzyme Activators; ErbB Receptors; Erlotinib Hydrochloride; Estrogen Receptor alpha; Female; Gene Expression Regulation, Neoplastic; Genetic Association Studies; Genetic Variation; Humans; Indazoles; Letrozole; MCF-7 Cells; Nitriles; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-vav; Quinazolines; RNA Interference; RNA, Small Interfering; Tamoxifen; Toremifene; Triazoles

2014
Optimization of an indazole series of selective estrogen receptor degraders: Tumor regression in a tamoxifen-resistant breast cancer xenograft.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cinnamates; Drug Resistance, Neoplasm; Estrogen Receptor Antagonists; Female; Indazoles; Rats; Structure-Activity Relationship; Tamoxifen; Xenograft Model Antitumor Assays

2015
Selective estrogen receptor degraders with novel structural motifs induce regression in a tamoxifen-resistant breast cancer xenograft.
    Bioorganic & medicinal chemistry letters, 2019, 02-01, Volume: 29, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cinnamates; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Indazoles; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Structure-Activity Relationship; Tamoxifen

2019
Therapeutic strategies to induce ERα in luminal breast cancer to enhance tamoxifen efficacy.
    Endocrine-related cancer, 2019, Volume: 26, Issue:8

    Topics: Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Everolimus; Female; Humans; Hydroxamic Acids; Indazoles; MCF-7 Cells; Paclitaxel; Sulfonamides; Tamoxifen; Tumor Cells, Cultured

2019
Pharmacological Inhibition of MCT4 Reduces 4-Hydroxytamoxifen Sensitivity by Increasing HIF-1α Protein Expression in ER-Positive MCF-7 Breast Cancer Cells.
    Biological & pharmaceutical bulletin, 2021, Volume: 44, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; MCF-7 Cells; Monocarboxylic Acid Transporters; Muscle Proteins; Propionates; Receptors, Estrogen; Tamoxifen

2021
Compressive stress-mediated p38 activation required for ERα + phenotype in breast cancer.
    Nature communications, 2021, 11-29, Volume: 12, Issue:1

    Topics: Breast Neoplasms; Case-Control Studies; Cell Line, Tumor; Cinnamates; Collagen; Drug Combinations; Enhancer of Zeste Homolog 2 Protein; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Indazoles; Laminin; Mammary Glands, Human; Mechanotransduction, Cellular; p38 Mitogen-Activated Protein Kinases; Phenotype; Proteoglycans; Tamoxifen; Tissue Culture Techniques; Transcriptome

2021