Compounds > indazoles
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indazoles and sapropterin

indazoles has been researched along with sapropterin in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Klatt, P; Leopold, E; Mayer, B; Schmid, M; Schmidt, K; Werner, ER1
Giovanelli, J; Kaufman, S; Witteveen, CF1
Alderton, WK; Boyhan, A; Lowe, PN1
Li, H; Martásek, P; Masters, BS; Poulos, TL; Raman, CS; Southan, G1
Caplan, MS; De Plaen, IG; Hsueh, W; Qu, XW; Rozenfeld, RA; Thaete, LG; Zhu, Y1

Other Studies

5 other study(ies) available for indazoles and sapropterin

ArticleYear
The pteridine binding site of brain nitric oxide synthase. Tetrahydrobiopterin binding kinetics, specificity, and allosteric interaction with the substrate domain.
    The Journal of biological chemistry, 1994, May-13, Volume: 269, Issue:19

    Topics: Allosteric Regulation; Amino Acid Oxidoreductases; Animals; Biopterins; Brain; Indazoles; Kinetics; Nitric Oxide Synthase; Pteridines; Substrate Specificity; Swine

1994
Reduction of quinonoid dihydrobiopterin to tetrahydrobiopterin by nitric oxide synthase.
    The Journal of biological chemistry, 1996, Feb-23, Volume: 271, Issue:8

    Topics: Animals; Arginine; Biopterins; Cell Line; Cerebellum; Enzyme Inhibitors; Humans; Indazoles; Kidney; Kinetics; Methotrexate; NADP; Nitric Oxide Synthase; Nitroarginine; Onium Compounds; Oxidation-Reduction; Rats; Recombinant Proteins; Transfection

1996
Nitroarginine and tetrahydrobiopterin binding to the haem domain of neuronal nitric oxide synthase using a scintillation proximity assay.
    The Biochemical journal, 1998, May-15, Volume: 332 ( Pt 1)

    Topics: Animals; Arginine; Binding Sites; Binding, Competitive; Biopterins; Enzyme Inhibitors; Heme; Indazoles; Isothiuronium; Kinetics; Nitric Oxide Synthase; Nitroarginine; Oxidoreductases; Oxygenases; Peptide Fragments; Protein Binding; Rats; Recombinant Fusion Proteins

1998
Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism.
    Biochemistry, 2001, Nov-13, Volume: 40, Issue:45

    Topics: Binding Sites; Biopterins; Crystallization; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Indazoles; Models, Molecular; Nitric Oxide Synthase; Nitroarginine; Protein Conformation; Substrate Specificity

2001
Tetrahydrobiopterin prevents platelet-activating factor-induced intestinal hypoperfusion and necrosis: Role of neuronal nitric oxide synthase.
    Critical care medicine, 2005, Volume: 33, Issue:5

    Topics: Animals; Antioxidants; Biopterins; Enzyme Inhibitors; Indazoles; Intestinal Diseases; Male; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Platelet Activating Factor; Pterins; Rats; Rats, Sprague-Dawley; Splanchnic Circulation

2005