Compounds > indazoles
Page last updated: 2024-08-21

indazoles and piperidine

indazoles has been researched along with piperidine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
COHEN, MP; SHAVEL, J; VONSTRANDTMANN, M1
Brodjian, S; Brune, M; Bush, E; Collins, CA; Dayton, B; Engstrom, KM; Falls, DH; Freeman, JC; Gao, J; Hernandez, LE; Kym, PR; Lynch, JK; Marsh, KC; Mulhern, MM; Shapiro, RD; Souers, AJ; Vasudevan, A; Verzal, MK; Wagaw, SH; Wodka, D1
Bader, SJ; Bagley, SW; Bernhardson, DJ; Cabral, S; Edmonds, DJ; Griffith, DA; Kung, DW; Polivkova, J; Rose, CR; Southers, JA; Yang, X1
Bridges, TM; Chase, P; Cho, HP; Conn, PJ; Daniels, JS; Gentry, PR; Hodder, PS; Kokubo, M; Lamsal, A; Lindsley, CW; Niswender, CM; Noetzel, MJ; Smith, E; Wood, MR1
Beno, BR; Chaturvedula, PV; Civiello, RL; Conway, CM; Dubowchik, GM; Han, X; Herbst, JJ; Macor, JE; Xu, C1

Other Studies

5 other study(ies) available for indazoles and piperidine

ArticleYear
ACYLTRYPTAMINES. II. SYNTHESIS OF ACYLTRYPTAMINES, INDAZOLES, AND AZEPINOINDOLES FROM THE ACYLPHENYLHYDRAZONES OF 2,3-PIPERIDINEDIONE.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Antihypertensive Agents; Blood Pressure; Chemistry, Pharmaceutical; Dogs; Heterocyclic Compounds; Indazoles; Indoles; Mice; Pharmacology; Piperidines; Research; Seizures; Selective Serotonin Reuptake Inhibitors; Serotonin; Toxicology; Tryptamines

1963
Aminopiperidine indazoles as orally efficacious melanin concentrating hormone receptor-1 antagonists.
    Bioorganic & medicinal chemistry letters, 2005, Dec-01, Volume: 15, Issue:23

    Topics: Administration, Oral; Animals; Anti-Obesity Agents; Humans; Indazoles; Mice; Piperidines; Receptors, Somatostatin; Tissue Distribution

2005
Synthesis of 7-oxo-dihydrospiro[indazole-5,4'-piperidine] acetyl-CoA carboxylase inhibitors.
    The Journal of organic chemistry, 2012, Feb-03, Volume: 77, Issue:3

    Topics: Acetyl-CoA Carboxylase; Alkenes; Alkylation; Chemistry Techniques, Synthetic; Enzyme Inhibitors; Indazoles; Ketones; Piperidines; Pyrazoles; Stereoisomerism; Substrate Specificity

2012
Development of a highly potent, novel M5 positive allosteric modulator (PAM) demonstrating CNS exposure: 1-((1H-indazol-5-yl)sulfoneyl)-N-ethyl-N-(2-(trifluoromethyl)benzyl)piperidine-4-carboxamide (ML380).
    Journal of medicinal chemistry, 2014, Sep-25, Volume: 57, Issue:18

    Topics: Allosteric Regulation; Animals; Central Nervous System; Drug Discovery; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Humans; Indazoles; Male; Piperidines; Rats; Receptor, Muscarinic M5; Substrate Specificity; Sulfonamides

2014
Synthesis and SAR of calcitonin gene-related peptide (CGRP) antagonists containing substituted aryl-piperazines and piperidines.
    Bioorganic & medicinal chemistry letters, 2016, Feb-15, Volume: 26, Issue:4

    Topics: Calcitonin Gene-Related Peptide; Cell Line, Tumor; Cell Membrane Permeability; Humans; Indazoles; Inhibitory Concentration 50; Piperazine; Piperazines; Piperidines; Quinazolinones; Structure-Activity Relationship

2016