Page last updated: 2024-08-21

indazoles and ondansetron

indazoles has been researched along with ondansetron in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.88)18.7374
1990's30 (88.24)18.2507
2000's2 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Airey, JE; Campbell, HF; Darkes, P; Fitzpatrick, LR; Klein, S; Neuenschwander, K; Pendley, CE; Powers, M; Schnapper, M; Youssefyeh, RD1
Andrews, PL; Bhandari, P; Bingham, S; Blower, PR; Davey, PT; Marr, HE1
Dilly, S1
Andrews, PL; Bingham, S; Joel, SP; Patel, N; Slevin, ML; Thompson, PI1
Sakamori, M; Setoguchi, M; Takehara, S1
Bosanquet, N; Jones, AL; Lee, GJ1
Cassuto, J; Jodal, M; Lundgren, O; Sjöqvist, A1
Barnes, NM; Cheng, CH; Costall, B; Ge, J; Kelly, ME; Naylor, RJ1
Aapro, M; Diehl, V; Kaye, SB; Khayat, D1
Ito, T; Omoya, H; Yoshida, N1
Soukop, M1
Smith, RA1
Ito, H; Iwai, A; Kamato, T; Katsuyama, Y; Miyata, K; Nishida, A; Ohta, M; Tsutsumi, R; Yamano, M; Yuki, H1
Andrews, PL; Bhandari, P1
Higgins, GA; Jones, BJ; Oakley, NR; Tyers, MB1
de Mulder, PH; Seynaeve, C; Verweij, J1
Itoh, Z; Iwanaga, Y; Mizumoto, A; Yoshida, N1
Itoh, Z; Iwanaga, Y; Mizumoto, A; Torii, K; Wakabayashi, K; Yoshida, N1
Gandara, DR; Hesketh, PJ1
Airey, JE; Bostwick, JS; Decktor, DL; Fitzpatrick, LR; Gessner, GW; Lambert, RM; Martin, GE; Pendleton, RG; Pendley, CE; Youssefyeh, RD1
Moss, HE; Sanger, GJ1
Brown, GW; Butcher, ME; Kidgell, AE1
File, SE; Johnston, AL1
Ito, A; Ito, T; Iwanaga, H; Karasawa, T; Mizumoto, A; Yoshida, N1
Blauw, GJ; Bruning, TA; Chang, PC; van Zwieten, PA; Vermeij, P1
Brown, NJ; Horton, A; Read, NW; Rumsey, RD1
Grahame-Smith, DG; Leslie, RA; Pei, Q; Zetterström, T1
Barnes, JM; Barnes, NM1
Snyman, JR; Sommers, DK; van Wyk, M1
Aapro, MS1
Barrett, JE; Critchett, D; Hu, W; Sokol, PT; Solomon, AJ; Toral, J; Ziai, MR1
Anzini, M; Cappelli, A; De Benedetti, PG; Donati, A; Langer, T; Menziani, MC; Vomero, S1
Barros, D; Carvalho, F; de Castro-E-Silva, E; Fregoneze, J; Rezende, E; Silva, J; Soares, M1
Bae, HB; Choi, JI; Chung, ST; Kim, CM; Kim, SJ; Yoon, MH1

Reviews

5 review(s) available for indazoles and ondansetron

ArticleYear
Are granisetron and ondansetron equivalent in the clinic?
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A Suppl 1

    Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Granisetron; Humans; Imidazoles; Indazoles; Nausea; Ondansetron; Serotonin Antagonists; Vomiting

1992
5-hydroxytryptamine-3 antagonists: a new class of potent antiemetics in cancer therapy.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1991, Volume: 121

    Topics: Animals; Antiemetics; Granisetron; Humans; Imidazoles; Indazoles; Ondansetron; Serotonin Antagonists

1991
5-HT3 receptor antagonists, a new approach in emesis: a review of ondansetron, granisetron and tropisetron.
    Anti-cancer drugs, 1991, Volume: 2, Issue:4

    Topics: Animals; Antiemetics; Granisetron; Humans; Imidazoles; Indazoles; Indoles; Ondansetron; Serotonin Antagonists; Tropisetron; Vomiting

1991
Antiemetic control: 5-HT3 antagonists: review of clinical results, with particular emphasis on ondansetron.
    Cancer treatment reviews, 1990, Volume: 17, Issue:2-3

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Granisetron; Headache; Humans; Imidazoles; Indazoles; Indoles; Nausea; Ondansetron; Radiation Injuries; Radiotherapy; Serotonin Antagonists; Tropisetron; Vomiting

1990
Review of experience with ondansetron and granisetron.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1993, Volume: 4 Suppl 3

    Topics: Antiemetics; Antineoplastic Agents; Granisetron; Humans; Indazoles; Nausea; Ondansetron; Serotonin Antagonists; Vomiting

1993

Trials

1 trial(s) available for indazoles and ondansetron

ArticleYear
Effect of metoclopramide, ondansetron and granisetron on aldosterone secretion in man.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:4

    Topics: Adult; Aldosterone; Granisetron; Humans; Indazoles; Male; Metoclopramide; Ondansetron; Receptors, Serotonin; Reference Values; Serotonin Antagonists; Single-Blind Method

1993

Other Studies

28 other study(ies) available for indazoles and ondansetron

ArticleYear
Development of high-affinity 5-HT3 receptor antagonists. 1. Initial structure-activity relationship of novel benzamides.
    Journal of medicinal chemistry, 1992, Mar-06, Volume: 35, Issue:5

    Topics: Animals; Antiemetics; Benzamides; Benzofurans; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Cisplatin; Ferrets; Granisetron; Imidazoles; Indazoles; Indoles; Male; Metoclopramide; Molecular Structure; Ondansetron; Rats; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Vomiting

1992
Are all 5-HT3 receptor antagonists the same?
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A Suppl 1

    Topics: Animals; Antiemetics; Cisplatin; Dose-Response Relationship, Drug; Ferrets; Granisetron; Imidazoles; Indazoles; Ondansetron; Serotonin Antagonists; Vomiting; Whole-Body Irradiation

1992
Morphine 6-glucuronide: a metabolite of morphine with greater emetic potency than morphine in the ferret.
    British journal of pharmacology, 1992, Volume: 106, Issue:1

    Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Emetics; Ferrets; Granisetron; Imidazoles; Indazoles; Injections, Subcutaneous; Morphine; Morphine Derivatives; Naloxone; Ondansetron; Vomiting

1992
[High affinity binding of Y-25130 for serotonin 3 receptor].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 100, Issue:2

    Topics: Animals; Antiemetics; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Granisetron; In Vitro Techniques; Indazoles; Male; Ondansetron; Oxazines; Rats; Rats, Wistar; Receptors, Serotonin; Synaptic Membranes

1992
The budgetary impact of 5-HT3 receptor antagonists in the management of chemotherapy-induced emesis.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 29A, Issue:1

    Topics: Antiemetics; Antineoplastic Agents; Drug Costs; Granisetron; Humans; Indazoles; Models, Theoretical; Nausea; Ondansetron; Serotonin Antagonists; Vomiting

1992
Actions of serotonin antagonists on cholera-toxin-induced intestinal fluid secretion.
    Acta physiologica Scandinavica, 1992, Volume: 145, Issue:3

    Topics: Animals; Body Fluids; Cholera Toxin; Female; Granisetron; Imidazoles; Indazoles; Intestinal Mucosa; Ketanserin; Lysergic Acid Diethylamide; Male; Methysergide; Ondansetron; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Zimeldine

1992
Profiles of interaction of R(+)/S(-)-zacopride and anxiolytic agents in a mouse model.
    European journal of pharmacology, 1992, Jul-21, Volume: 218, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Antiemetics; Behavior, Animal; Benzamides; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlordiazepoxide; Fenclonine; Granisetron; Indazoles; Male; Mice; Neurotransmitter Agents; Ondansetron; Receptors, Cholecystokinin; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Stereoisomerism

1992
Who should receive a 5-HT3 antagonist?
    Lancet (London, England), 1992, Oct-31, Volume: 340, Issue:8827

    Topics: Acute Disease; Antineoplastic Agents; Granisetron; Humans; Indazoles; Nausea; Ondansetron; Serotonin Antagonists; Vomiting

1992
DAT-582, a novel serotonin3 receptor antagonist, is a potent and long-lasting antiemetic agent in the ferret and dog.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3

    Topics: Animals; Antiemetics; Azepines; Cisplatin; Copper; Copper Sulfate; Dogs; Female; Ferrets; Gastric Emptying; Imidazoles; Indazoles; Male; Nicotine; Ondansetron; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Shrews

1992
5-HT3 receptor blockers.
    Surgery, 1991, Volume: 110, Issue:3

    Topics: Granisetron; Humans; Imidazoles; Indazoles; Ondansetron; Receptors, Serotonin; Vagus Nerve

1991
Pharmacologic profile of (R)-5-[(1-methyl-3-indolyl)carbonyl]-4,5,6,7-tetrahydro-1H- benzimidazole hydrochloride (YM060), a potent and selective 5-hydroxytryptamine3 receptor antagonist, and its enantiomer in the isolated tissue.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:1

    Topics: Animals; Benzimidazoles; Dogs; Female; Granisetron; Guinea Pigs; Imidazoles; Indazoles; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardial Contraction; Ondansetron; Receptors, Adrenergic; Receptors, Histamine; Serotonin Antagonists; Stereoisomerism

1991
Preliminary evidence for the involvement of the putative 5-HT4 receptor in zacopride- and copper sulphate-induced vomiting in the ferret.
    European journal of pharmacology, 1991, Nov-12, Volume: 204, Issue:3

    Topics: Analysis of Variance; Animals; Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Copper; Copper Sulfate; Female; Ferrets; Granisetron; Imidazoles; Indazoles; Indoles; Loperamide; Male; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Tropisetron; Vomiting

1991
Evidence that the amygdala is involved in the disinhibitory effects of 5-HT3 receptor antagonists.
    Psychopharmacology, 1991, Volume: 104, Issue:4

    Topics: Amygdala; Animals; Anxiety; Conflict, Psychological; Granisetron; Imidazoles; Indazoles; Indoles; Lighting; Male; Ondansetron; Raphe Nuclei; Rats; Serotonin; Serotonin Antagonists; Social Behavior; Tropanes; Tropisetron

1991
Effects of 5-hydroxytryptamine 3 receptor antagonists on gastrointestinal motor activity in conscious dogs.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1

    Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Digestion; Dogs; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Granisetron; Imidazoles; Indazoles; Indoles; Infusions, Intravenous; Injections, Intravenous; Male; Motilin; Motor Activity; Muscle Contraction; Muscle, Smooth; Ondansetron; Serotonin Antagonists; Time Factors; Tropisetron

1991
Involvement of 5-hydroxytryptamine 3 receptors in regulation of interdigestive gastric contractions by motilin in the dog.
    Gastroenterology, 1991, Volume: 100, Issue:4

    Topics: Acetylcholine; Animals; Digestion; Dogs; Gastrointestinal Motility; Granisetron; Imidazoles; Indazoles; Motilin; Muscle Contraction; Muscle, Smooth; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Stomach

1991
Serotonin antagonists: a new class of antiemetic agents.
    Journal of the National Cancer Institute, 1991, May-01, Volume: 83, Issue:9

    Topics: Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Granisetron; Humans; Imidazoles; Indazoles; Indoles; Metoclopramide; Ondansetron; Quinolizines; Receptors, Serotonin; Serotonin Antagonists; Tropanes; Tropisetron; Vomiting

1991
RG 12915: a potent 5-hydroxytryptamine-3 antagonist that is an orally effective inhibitor of cytotoxic drug-induced emesis in the ferret and dog.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2

    Topics: Administration, Oral; Animals; Antiemetics; Antineoplastic Agents; Benzofurans; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cisplatin; Dogs; Dopamine; Ferrets; Gastric Emptying; Granisetron; Imidazoles; Indazoles; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Vomiting

1990
The effects of granisetron, ICS 205-930 and ondansetron on the visceral pain reflex induced by duodenal distension.
    British journal of pharmacology, 1990, Volume: 100, Issue:3

    Topics: Animals; Blood Pressure; Duodenum; Granisetron; Imidazoles; Indazoles; Indoles; Male; Morphine; Muscle Contraction; Muscle, Smooth; Ondansetron; Pain; Pyrazoles; Rats; Rats, Inbred Strains; Reflex; Serotonin Antagonists; Stomach; Tropisetron; Vagotomy

1990
Lack of effects of 5HT3 receptor antagonists in the social interaction and elevated plus-maze tests of anxiety in the rat.
    Psychopharmacology, 1989, Volume: 99, Issue:2

    Topics: Animals; Anxiety; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlordiazepoxide; Granisetron; Imidazoles; Indazoles; Male; Motor Activity; Ondansetron; Rats; Serotonin Antagonists; Social Behavior

1989
[Effect of 5-HT3 receptor antagonists on gastrointestinal motility].
    Nihon Heikatsukin Gakkai zasshi, 1989, Volume: 25, Issue:6

    Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Gastrointestinal Motility; Granisetron; Imidazoles; In Vitro Techniques; Indazoles; Indoles; Motilin; Ondansetron; Rabbits; Serotonin Antagonists; Tropisetron

1989
Serotonin-induced vasodilatation in the human forearm is mediated by the "nitric oxide-pathway": no evidence for involvement of the 5-HT3-receptor.
    Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:1

    Topics: Adult; Amino Acid Oxidoreductases; Arginine; Forearm; Free Radical Scavengers; Granisetron; Guanylate Cyclase; Humans; Indazoles; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ondansetron; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Vasodilation

1993
Granisetron and ondansetron: effects on the ileal brake mechanism in the rat.
    The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:6

    Topics: Animals; Dose-Response Relationship, Drug; Gastrointestinal Transit; Granisetron; Ileum; Indazoles; Lipids; Male; Ondansetron; Rats; Sensitivity and Specificity; Serotonin Antagonists

1993
5-HT3 receptor antagonists inhibit morphine-induced stimulation of mesolimbic dopamine release and function in the rat.
    European journal of pharmacology, 1993, Jan-05, Volume: 230, Issue:1

    Topics: Animals; Behavior, Animal; Dialysis; Dopamine; Dose-Response Relationship, Drug; Granisetron; Indazoles; Indoles; Limbic System; Male; Morphine; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tropisetron

1993
Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron.
    Biochemical pharmacology, 1993, May-25, Volume: 45, Issue:10

    Topics: Animals; Benzamides; Biguanides; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Glioma; Granisetron; Indazoles; Kinetics; Neuroblastoma; Ondansetron; Quipazine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium

1993
5-HT3 receptor-independent inhibition of the depolarization-induced 86Rb efflux from human neuroblastoma cells, TE671, by ondansetron.
    The Journal of pharmacy and pharmacology, 1995, Volume: 47, Issue:7

    Topics: Anti-Anxiety Agents; Benzamides; Benzofurans; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; Humans; Hypoglycemic Agents; Indazoles; Indoles; Neuroblastoma; Neurotoxins; Ondansetron; Potassium Channels; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Rubidium Radioisotopes; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Tropanes; Tropisetron; Tumor Cells, Cultured

1995
Molecular structure and dynamics of some potent 5-HT3 receptor antagonists. Insight into the interaction with the receptor.
    Bioorganic & medicinal chemistry, 1996, Volume: 4, Issue:8

    Topics: Affinity Labels; Indazoles; Lipid Metabolism; Magnetic Resonance Spectroscopy; Models, Molecular; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Software; Structure-Activity Relationship; Temperature; Tropanes

1996
Hyperglycemia induced by pharmacological activation of central serotonergic pathways depends on the functional integrity of brain CRH system and 5-HT3 receptors.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2005, Volume: 37, Issue:8

    Topics: Animals; Blood Glucose; Corticotropin-Releasing Hormone; Hyperglycemia; Indazoles; Insulin; Male; Ondansetron; Quipazine; Rats; Rats, Wistar; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes

2005
Lack of reciprocity between opioid and 5-HT3 receptors for antinociception in rat spinal cord.
    Pharmacology, 2006, Volume: 77, Issue:4

    Topics: Analgesia; Analgesics, Opioid; Animals; Biguanides; Dose-Response Relationship, Drug; Formaldehyde; Hindlimb; Indazoles; Injections, Spinal; Male; Morphine; Motor Activity; Muscle Tonus; Naloxone; Narcotic Antagonists; Ondansetron; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Spinal Cord; Tropanes

2006