Compounds > indazoles
Page last updated: 2024-08-21

indazoles and n2-(1h-indazole-5-yl)-n6-methyl-3-nitropyridine-2,6-diamine

indazoles has been researched along with n2-(1h-indazole-5-yl)-n6-methyl-3-nitropyridine-2,6-diamine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Han, DC; Han, YM; Kim, JA; Kwon, BM; Lee, JS; Lee, YJ; Shin, DS; Shin, KD; Yoon, YJ1
Huang, C; Jiang, B; Lu, X; Tong, L; Wang, J; Yang, R; Zhang, W1
Kang, MJ; Lee, JH; Yun, HH1
Benneyworth, M; Lin, YL; Liu, PY; Tsai, HC; Wei, LN1
Belaya, Z; Buchfelder, M; Ciato, D; D'Annunzio, S; Hristov, M; Li, R; Monteserin Garcia, JL; Paez-Pereda, M; Papst, L; Rozhinskaya, L; Stalla, GK; Theodoropoulou, M; Tichomirowa, MA1
Han, X; Lu, C; Lv, S; Qiao, P; Ren, C; Sun, Y; Wang, D; Wang, L; Yang, T; Yu, Z1
Ren, C; Wang, Y; Xiu, J; Yang, T; Yu, Z1
He, X; Ji, X; Jiang, C; Shen, Z; Yin, L; Zhou, H; Zhu, X1
Jung, SY; Lee, JH; Yoo, K; Yun, HH1

Other Studies

9 other study(ies) available for indazoles and n2-(1h-indazole-5-yl)-n6-methyl-3-nitropyridine-2,6-diamine

ArticleYear
KRIBB11 inhibits HSP70 synthesis through inhibition of heat shock factor 1 function by impairing the recruitment of positive transcription elongation factor b to the hsp70 promoter.
    The Journal of biological chemistry, 2011, Jan-21, Volume: 286, Issue:3

    Topics: Aminopyridines; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Diamines; DNA-Binding Proteins; Drug Delivery Systems; Heat Shock Transcription Factors; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Indazoles; Mice; Mice, Nude; Molecular Chaperones; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms; Poly(ADP-ribose) Polymerases; Positive Transcriptional Elongation Factor B; Promoter Regions, Genetic; Transcription Factors

2011
Requirement for endogenous heat shock factor 1 in inducible nitric oxide synthase induction in murine microglia.
    Journal of neuroinflammation, 2015, Oct-14, Volume: 12

    Topics: Aminopyridines; Animals; Animals, Newborn; Cell Survival; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Heat Shock Transcription Factors; Indazoles; Interferon-gamma; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; NF-kappa B; Nitric Oxide Synthase Type II; Protein Binding; RNA, Messenger; RNA, Small Interfering; Signal Transduction; STAT1 Transcription Factor; Transcription Factors

2015
KRIBB11 accelerates Mcl-1 degradation through an HSF1-independent, Mule-dependent pathway in A549 non-small cell lung cancer cells.
    Biochemical and biophysical research communications, 2017, 10-21, Volume: 492, Issue:3

    Topics: Aminopyridines; Apoptosis; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Heat Shock Transcription Factors; HSP70 Heat-Shock Proteins; Humans; Indazoles; Lung Neoplasms; Myeloid Cell Leukemia Sequence 1 Protein; Proteasome Endopeptidase Complex; Proteolysis; Transcription Factors; Tumor Cells, Cultured; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases

2017
Receptor-interacting protein 140 as a co-repressor of Heat Shock Factor 1 regulates neuronal stress response.
    Cell death & disease, 2017, 12-12, Volume: 8, Issue:12

    Topics: Adaptor Proteins, Signal Transducing; Aminopyridines; Animals; Arsenites; Cell Line; Embryo, Mammalian; Gene Expression Regulation; Genetic Vectors; Heat Shock Transcription Factors; Heat-Shock Response; Hippocampus; Hot Temperature; Indazoles; Lentivirus; Maze Learning; Mice; Mice, Inbred C57BL; Neurons; Nuclear Proteins; Nuclear Receptor Interacting Protein 1; Primary Cell Culture; RNA, Small Interfering; Rotarod Performance Test; Signal Transduction; Sodium Compounds; Spatial Behavior; Syk Kinase

2017
Inhibition of Heat Shock Factor 1 Enhances Repressive Molecular Mechanisms on the POMC Promoter.
    Neuroendocrinology, 2019, Volume: 109, Issue:4

    Topics: Adrenocorticotropic Hormone; Adult; Aminopyridines; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Female; Gene Silencing; Heat Shock Transcription Factors; Humans; Immunohistochemistry; Indazoles; Male; Pituitary ACTH Hypersecretion; Pro-Opiomelanocortin; RNA Interference; Transcription Factor AP-1; Transcriptional Activation; Young Adult

2019
Phosphorylation of HSF1 by PIM2 Induces PD-L1 Expression and Promotes Tumor Growth in Breast Cancer.
    Cancer research, 2019, Oct-15, Volume: 79, Issue:20

    Topics: Aminopyridines; Animals; Autophagy; B7-H1 Antigen; Benzylidene Compounds; Breast Neoplasms; Carboplatin; F-Box-WD Repeat-Containing Protein 7; Female; Gene Expression Regulation, Neoplastic; Heat Shock Transcription Factors; Humans; Indazoles; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Targeted Therapy; Neoplasm Proteins; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Stability; Proto-Oncogene Proteins; RNA Interference; RNA, Small Interfering; Substrate Specificity; Thiazolidinediones; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays

2019
HSF1 promotes endometriosis development and glycolysis by up-regulating PFKFB3 expression.
    Reproductive biology and endocrinology : RB&E, 2021, Jun-09, Volume: 19, Issue:1

    Topics: Aminopyridines; Animals; Blotting, Western; Cell Count; Cell Line; Cell Movement; Cell Proliferation; Disease Models, Animal; Endometriosis; Female; Gene Knockdown Techniques; Glucose; Glycolysis; Heat Shock Transcription Factors; Humans; Indazoles; Lactic Acid; Mice; Phosphofructokinase-2; Real-Time Polymerase Chain Reaction; Up-Regulation

2021
Combined inhibition of AURKA and HSF1 suppresses proliferation and promotes apoptosis in hepatocellular carcinoma by activating endoplasmic reticulum stress.
    Cellular oncology (Dordrecht), 2021, Volume: 44, Issue:5

    Topics: Aminopyridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aurora Kinase A; Benzamides; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Endoplasmic Reticulum Stress; Female; Gene Expression Regulation, Neoplastic; Heat Shock Transcription Factors; Hep G2 Cells; Humans; Indazoles; Kaplan-Meier Estimate; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; Pyrazoles; RNA Interference; Xenograft Model Antitumor Assays

2021
KRIBB11 Induces Apoptosis in A172 Glioblastoma Cells via MULE-Dependent Degradation of MCL-1.
    Molecules (Basel, Switzerland), 2021, Jul-08, Volume: 26, Issue:14

    Topics: Aminopyridines; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Glioblastoma; Glioma; Humans; Indazoles; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Proteins; Ubiquitin; Ubiquitin-Protein Ligases

2021