Page last updated: 2024-08-21

indazoles and n-((3s)-1-azabicyclo(2.2.2)oct-3-yl)-1h-indazole-3-carboxamide hydrochloride

indazoles has been researched along with n-((3s)-1-azabicyclo(2.2.2)oct-3-yl)-1h-indazole-3-carboxamide hydrochloride in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bertrand, D; Callahan, PM; Graham, E; Herbert, B; Lowe, DA; Murray, M; Ong, V; Porter, R; Rodefer, JS; Rowe, WB; Santarelli, L; Tehim, A; Terry, AV; Tombaugh, G; Wallace, TL; Wang, S; Xie, W1
Felix, AR; Huang, M; Kwon, S; Lowe, D; Meltzer, HY; Santarelli, L; Wallace, T1
Garibaldi, G; Keefe, RS; Lowe, DA; Murray, S; Porter, R; Santarelli, L; Umbricht, D1
Hao, Y; Tang, J; Wang, K1
Dong, EZ; Jennings, G; Kuang, S; Pierce, M; Zhang, P; Zhao, B1
Bassett, S; Boess, F; Funk, J; Lenz, B; Niederhauser, U; Roth, AB; Singer, T; Zhang, JD1

Trials

1 trial(s) available for indazoles and n-((3s)-1-azabicyclo(2.2.2)oct-3-yl)-1h-indazole-3-carboxamide hydrochloride

ArticleYear
A randomized, placebo-controlled study investigating the nicotinic α7 agonist, RG3487, for cognitive deficits in schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:7

    Topics: Adolescent; Adult; Antipsychotic Agents; Bridged Bicyclo Compounds; Cognition Disorders; Double-Blind Method; Female; Humans; Indazoles; Male; Middle Aged; Neuropsychological Tests; Nicotinic Agonists; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Treatment Outcome; Young Adult

2014

Other Studies

5 other study(ies) available for indazoles and n-((3s)-1-azabicyclo(2.2.2)oct-3-yl)-1h-indazole-3-carboxamide hydrochloride

ArticleYear
RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 336, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Binding, Competitive; Bridged Bicyclo Compounds; Cell Line, Tumor; Cognition; Drug Partial Agonism; Female; Humans; Indazoles; Male; Nicotinic Agonists; Rats; Rats, Inbred F344; Rats, Long-Evans; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Nicotinic; Sensory Gating; Xenopus laevis

2011
The alpha-7 nicotinic receptor partial agonist/5-HT3 antagonist RG3487 enhances cortical and hippocampal dopamine and acetylcholine release.
    Psychopharmacology, 2014, Volume: 231, Issue:10

    Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged Bicyclo Compounds; Cerebral Cortex; Dopamine; Hippocampus; Indazoles; Male; Rats; Rats, Sprague-Dawley; Serotonin 5-HT3 Receptor Antagonists

2014
Development of Automated Patch Clamp Assay for Evaluation of α7 Nicotinic Acetylcholine Receptor Agonists in Automated QPatch-16.
    Assay and drug development technologies, 2015, Volume: 13, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Automation; Bridged Bicyclo Compounds; Humans; Indazoles; Isoxazoles; Nicotinic Agonists; Patch-Clamp Techniques; Phenylurea Compounds; Quinuclidines; Rats; Thiophenes; Tumor Cells, Cultured

2015
Crystal form control and particle size control of RG3487, a nicotinic α7 receptor partial agonist.
    International journal of pharmaceutics, 2016, Jul-11, Volume: 508, Issue:1-2

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Bridged Bicyclo Compounds; Chemistry, Pharmaceutical; Crystallization; Drug Partial Agonism; Indazoles; Molecular Structure; Particle Size; Thermodynamics

2016
Use of early phenotypic in vivo markers to assess human relevance of an unusual rodent non-genotoxic carcinogen in vitro.
    Toxicology, 2017, 03-15, Volume: 379

    Topics: Animals; Biomarkers; Bridged Bicyclo Compounds; Carcinogens; Cells, Cultured; DNA Replication; Dogs; Gene Expression Regulation; Hepatocytes; Humans; Indazoles; Male; Mice; Phenotype; Rats; Species Specificity

2017