indazoles has been researched along with morphine in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (34.62) | 18.2507 |
| 2000's | 11 (42.31) | 29.6817 |
| 2010's | 5 (19.23) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PL; Bingham, S; Joel, SP; Patel, N; Slevin, ML; Thompson, PI | 1 |
| Moss, HE; Sanger, GJ | 1 |
| Grahame-Smith, DG; Leslie, RA; Pei, Q; Zetterström, T | 1 |
| Kimes, AS; London, ED; Vaupel, DB | 2 |
| Bhargava, HN; Cao, YJ; Zhao, GM | 1 |
| Fairbanks, CA; Wilcox, GL | 1 |
| Martín-Ruiz, R; Pineda, J; Torrecilla, M; Ugedo, L | 1 |
| Bespalov, AY; Dravolina, OA; Medvedev, IO | 1 |
| Dahan, A; Olievier, CN; Sarton, E; Teppema, L | 1 |
| Barr, GA; Zhu, H | 1 |
| Garcia, MM; Harlan, RE; Webber, DS | 1 |
| Adler, MW; Benamar, K; Geller, EB; Kon, D; Yondorf, MZ | 1 |
| Aguilar, MA; Manzanedo, C; Miñarro, J; Navarro, M; Rodríguez-Arias, M | 1 |
| Pineda, J; Santamarta, MT; Ulibarri, I | 1 |
| Ando, K; Harada, E; Hayashida, K; Shimizu, H; Takeuchi, T; Tsuchiya, T | 1 |
| Bae, HB; Choi, JI; Chung, ST; Kim, CM; Kim, SJ; Yoon, MH | 1 |
| Chen, PX; Cui, Y; Feng, JQ; Liu, W; Mo, LQ; Sun, SN; Wang, CH; Wang, YL; Yu, HM; Zhao, CM; Zhi, JL | 1 |
| Bagetta, G; Komatsu, T; Sakurada, C; Sakurada, S; Sakurada, T; Sanai, K; Sasaki, M; Tsuzuki, M | 1 |
| Aguilar, MA; Do Couto, BR; Manzanedo, C; Miñarro, J; Rodríguez-Arias, M | 1 |
| Altun, A; Bagcivan, I; Durmus, N; Gursoy, S; Ozdemir, E | 1 |
| Abdel-Hady, RH; Abdel-Zaher, AO; Farghaly, HS; Hamdy, MM; Mostafa, MG | 1 |
| Makuch, W; Mika, J; Przewlocka, B; Rojewska, E; Zychowska, M | 1 |
| Chang, HF; Chang, WT; Chao, PK; Chen, CT; Chen, SC; Cheng, MF; Chuang, JY; Law, PY; Loh, HH; Ou, LC; Shih, C; Tao, PL; Ueng, SH; Yeh, SH; Yeh, TK | 1 |
| Dehpour, AR; Faghir-Ghanesefat, H; Gholami, M; Meskinimood, S; Rahimi, N; Sharifzadeh, M | 1 |
| Zhai, H; Zhang, Y | 1 |
1 review(s) available for indazoles and morphine
| Article | Year |
|---|---|
Nitric oxide synthase inhibitors. Preclinical studies of potential use for treatment of opioid withdrawal.
Topics: Adrenergic alpha-Agonists; Animals; Arginine; Blood Pressure; Clonidine; Depression, Chemical; Enzyme Inhibitors; Heart Rate; Indazoles; Morphine; Narcotics; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Opioid-Related Disorders; Ornithine; Substance Withdrawal Syndrome | 1995 |
25 other study(ies) available for indazoles and morphine
| Article | Year |
|---|---|
Morphine 6-glucuronide: a metabolite of morphine with greater emetic potency than morphine in the ferret.
Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Emetics; Ferrets; Granisetron; Imidazoles; Indazoles; Injections, Subcutaneous; Morphine; Morphine Derivatives; Naloxone; Ondansetron; Vomiting | 1992 |
The effects of granisetron, ICS 205-930 and ondansetron on the visceral pain reflex induced by duodenal distension.
Topics: Animals; Blood Pressure; Duodenum; Granisetron; Imidazoles; Indazoles; Indoles; Male; Morphine; Muscle Contraction; Muscle, Smooth; Ondansetron; Pain; Pyrazoles; Rats; Rats, Inbred Strains; Reflex; Serotonin Antagonists; Stomach; Tropisetron; Vagotomy | 1990 |
5-HT3 receptor antagonists inhibit morphine-induced stimulation of mesolimbic dopamine release and function in the rat.
Topics: Animals; Behavior, Animal; Dialysis; Dopamine; Dose-Response Relationship, Drug; Granisetron; Indazoles; Indoles; Limbic System; Male; Morphine; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tropisetron | 1993 |
Further in vivo studies on attenuating morphine withdrawal: isoform-selective nitric oxide synthase inhibitors differ in efficacy.
Topics: Analysis of Variance; Animals; Blood Pressure; Citrulline; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Guanidines; Heart Rate; Indazoles; Isoenzymes; Male; Morphine; Naloxone; Narcotic Antagonists; Nitric Oxide Synthase; Rats; Rats, Inbred F344; Substance Withdrawal Syndrome; Thiourea | 1997 |
Effect of 7-nitroindazole on tolerance to morphine, U-50,488H and [D-Pen2, D-Pen5] enkephalin in mice.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Drug Tolerance; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Enzyme Inhibitors; Indazoles; Male; Mice; Morphine; Nitric Oxide Synthase; Nociceptors; Receptors, Opioid, delta; Receptors, Opioid, kappa | 1997 |
Acute tolerance to spinally administered morphine compares mechanistically with chronically induced morphine tolerance.
Topics: Agmatine; Analgesics, Opioid; Animals; Drug Tolerance; Indazoles; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morphine; Nitric Oxide Synthase; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1997 |
Attenuation of withdrawal-induced hyperactivity of locus coeruleus neurones by inhibitors of nitric oxide synthase in morphine-dependent rats.
Topics: Animals; Electrophysiology; Enzyme Inhibitors; Indazoles; Locus Coeruleus; Male; Morphine; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1998 |
Differential effects of nitric oxide synthase inhibitor, 7-nitroindazole, on discriminative stimulus and somatic effects of naloxone in morphine-dependent rats.
Topics: Analgesics, Opioid; Animals; Body Weight; Discrimination Learning; Drug Interactions; Enzyme Inhibitors; Indazoles; Male; Maze Learning; Morphine; Naloxone; Narcotic Antagonists; Nitric Oxide Synthase; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Substance-Related Disorders | 1999 |
The neuronal nitric oxide synthase inhibitor 7-nitroindazole (7-NI) and morphine act independently on the control of breathing.
Topics: Analgesics; Analgesics, Opioid; Animals; Carbon Dioxide; Cats; Drug Interactions; Enzyme Inhibitors; Female; Indazoles; Male; Morphine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Respiration | 2000 |
Naltrexone-precipitated morphine withdrawal in infant rat is attenuated by acute administration of NOS inhibitors but not NMDA receptor antagonists.
Topics: 2-Amino-5-phosphonovalerate; Aging; Animals; Animals, Newborn; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Humans; Indazoles; Infant, Newborn; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Neonatal Abstinence Syndrome; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate | 2000 |
Involvement of nitric oxide in morphine-induced c-Fos expression in the rat striatum.
Topics: Animals; Caudate Nucleus; Corpus Striatum; Enzyme Inhibitors; Genes, fos; Indazoles; Interneurons; Male; Morphine; Narcotics; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Putamen; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2001 |
Role of the nitric-oxide synthase isoforms during morphine-induced hyperthermia in rats.
Topics: Animals; Body Temperature; Drug Interactions; Enzyme Inhibitors; Fever; Guanidines; Indazoles; Infusions, Parenteral; Isoenzymes; Male; Morphine; Nitric Oxide Synthase; Ornithine; Rats; Rats, Sprague-Dawley | 2003 |
7-Nitroindazole blocks conditioned place preference but not hyperactivity induced by morphine.
Topics: Analgesics, Opioid; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperkinesis; Indazoles; Male; Mice; Morphine; Motor Activity; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Reward | 2004 |
Inhibition of neuronal nitric oxide synthase attenuates the development of morphine tolerance in rats.
Topics: Analgesics, Opioid; Animals; Drug Tolerance; Enkephalin, Methionine; Enzyme Inhibitors; Extracellular Space; In Vitro Techniques; Indazoles; Locus Coeruleus; Male; Morphine; Nerve Tissue Proteins; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time | 2005 |
Milk-derived lactoferrin may block tolerance to morphine analgesia.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Tolerance; Enzyme Inhibitors; Guanylate Cyclase; Indazoles; Infusions, Parenteral; Lactoferrin; Male; Methylene Blue; Mice; Mice, Inbred ICR; Milk; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type I; Pain Measurement; Reaction Time; Receptors, Opioid, mu | 2006 |
Lack of reciprocity between opioid and 5-HT3 receptors for antinociception in rat spinal cord.
Topics: Analgesia; Analgesics, Opioid; Animals; Biguanides; Dose-Response Relationship, Drug; Formaldehyde; Hindlimb; Indazoles; Injections, Spinal; Male; Morphine; Motor Activity; Muscle Tonus; Naloxone; Narcotic Antagonists; Ondansetron; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Spinal Cord; Tropanes | 2006 |
Inhibition of neuronal nitric oxide synthase antagonizes morphine antinociceptive tolerance by decreasing activation of p38 MAPK in the spinal microglia.
Topics: Analysis of Variance; Animals; Cell Count; Drug Interactions; Drug Tolerance; Enzyme Activation; Enzyme Inhibitors; Fluorescent Antibody Technique; Indazoles; Injections, Spinal; Male; Microglia; Morphine; Narcotics; Nitric Oxide Synthase Type I; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Spinal Cord | 2006 |
Extracellular signal-regulated kinase (ERK) and nitric oxide synthase mediate intrathecal morphine-induced nociceptive behavior.
Topics: Amidines; Analgesics, Opioid; Animals; Behavior, Animal; Benzylamines; Blotting, Western; Butadienes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Indazoles; Injections, Spinal; Male; Mice; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitriles; Nociceptors; Pain; Signal Transduction | 2007 |
Involvement of nitric oxide synthesis in sensitization to the rewarding effects of morphine.
Topics: Animals; Conditioning, Classical; Indazoles; Male; Mice; Morphine; Narcotics; Nitric Oxide; Nitric Oxide Synthase; Reward | 2009 |
The nitric oxide-cGMP signaling pathway plays a significant role in tolerance to the analgesic effect of morphine.
Topics: Analgesics, Opioid; Animals; Cyclic GMP; Drug Tolerance; Guanylate Cyclase; Indazoles; Male; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Soluble Guanylyl Cyclase | 2011 |
Role of oxidative stress and inducible nitric oxide synthase in morphine-induced tolerance and dependence in mice. Effect of alpha-lipoic acid.
Topics: Animals; Arginine; Brain; Drug Tolerance; Enzyme Inhibitors; Glutamic Acid; Glutathione; Indazoles; Male; Malondialdehyde; Mice; Morphine; Morphine Dependence; Nitric Oxide Synthase Type II; Oxidative Stress; Thioctic Acid | 2013 |
Effects of selective and non-selective inhibitors of nitric oxide synthase on morphine- and endomorphin-1-induced analgesia in acute and neuropathic pain in rats.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglia, Spinal; Indazoles; Male; Membrane Glycoproteins; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligopeptides; Pain Measurement; Rats; Rats, Wistar; Receptors, Complement; RNA, Messenger; Sciatica; Spinal Cord; Time Factors | 2013 |
1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Gastrointestinal Diseases; Indazoles; Male; Mice; Mice, Inbred C57BL; Morphine; Receptors, Opioid | 2017 |
Modulatory effect of opioid ligands on status epilepticus and the role of nitric oxide pathway.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Indazoles; Ligands; Lithium Chloride; Male; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pentylenetetrazole; Pilocarpine; Rats; Rats, Wistar; Signal Transduction; Status Epilepticus | 2019 |
Bilobalide assuages morphine-induced addiction in hippocampal neuron cells through upregulation of microRNA-101.
Topics: Animals; Animals, Newborn; Cells, Cultured; Cyclopentanes; Furans; Ginkgo biloba; Ginkgolides; Hippocampus; Indazoles; MAP Kinase Signaling System; MicroRNAs; Morphine; Neurons; Orexin Receptors; Oxaliplatin; Piperazines; Plant Extracts; Protein Kinase C; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Transfection; Up-Regulation | 2020 |