indazoles has been researched along with ly 278584 in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.13) | 18.7374 |
| 1990's | 15 (46.88) | 18.2507 |
| 2000's | 11 (34.38) | 29.6817 |
| 2010's | 5 (15.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fletcher, PW; Miller, K; Teitler, M; Weisberg, E | 1 |
| Champaneria, S; Costall, B; Naylor, RJ; Robertson, DW | 1 |
| Gackenheimer, SL; Gehlert, DR; Robertson, DW; Wong, DT | 1 |
| Bloomquist, W; Cohen, ML; Reid, LR; Robertson, DW; Schenck, K; Wong, DT | 1 |
| Reid, LR; Robertson, DW; Wong, DT | 1 |
| Harris, RA; Klein, RL; McQuilkin, SJ; Sanna, E; Whiting, PJ | 1 |
| Hyde, TM; Kleinman, JE; Knable, MB; Ohuoha, DC; Wolf, SS | 1 |
| Abi-Dargham, A; Jaskiw, GE; Kleinman, JE; Laruelle, M; Lipska, B; Robertson, DW; Weinberger, DR; Wong, DT | 1 |
| Abi-Dargham, A; Kleinman, JE; Laruelle, M; Robertson, DW; Weinberger, DR; Wong, DT | 1 |
| Barrett, JE; Critchett, D; Hu, W; Sokol, PT; Solomon, AJ; Toral, J; Ziai, MR | 1 |
| Anzini, M; Cappelli, A; De Benedetti, PG; Donati, A; Langer, T; Menziani, MC; Vomero, S | 1 |
| Arango, V; Henteleff, RA; Lagattuta, TF; Mann, JJ; Wong, DT | 1 |
| Labeaga, L; Mosquera, R; Orjales, A; Rodes, R | 1 |
| Hillsley, K; Mawe, GM | 1 |
| Foxx-Orenstein, AE; Grider, JR; Jin, JG | 1 |
| Akagawa, Y; Hishikawa, Y; Maruyama, A; Masuda, Y; Shimizu, T | 1 |
| Castro, G; Hilburn, C; King, GR; Konen, J; Pinto, G; Tran, S | 1 |
| Morales, M; Oz, M; Zhang, L | 1 |
| Campos, I; Castro, L; De Castro-e-Silva, E; Duque, B; Fregoneze, J; Maldonado, I; Reis de Oliveira, I; Varjão, B | 1 |
| Berry, N; McBride, WJ; McKinzie, DL; Melendez, RI; Murphy, JM; Rodd-Henricks, ZA | 1 |
| Angelo, AL; Athanazio, R; Barbetta, M; Campos, I; Castro, L; de Castro e Silva, E; Ferreira, H; Fregoneze, J; Ramos, AC; Varjão, B | 1 |
| Furukawa, K; Ishii, N; Nagao, K; Uchiyama, T | 1 |
| Morales, M; Oz, M; Rotondo, A; Sun, H; Zhang, L | 1 |
| Besheer, J; Bratt, AM; Hodge, CW; Iller, K; Kelley, SP; Schroeder, JP | 1 |
| Barros, D; Carvalho, F; de Castro-E-Silva, E; Fregoneze, J; Rezende, E; Silva, J; Soares, M | 1 |
| Emmanouil, DE; Hagihara, PT; Papadopoulou-Daifoti, Z; Quock, DG; Quock, RM | 1 |
| Bae, HB; Choi, JI; Chung, ST; Kim, CM; Kim, SJ; Yoon, MH | 1 |
| Asano, H; Funakami, Y; Ichida, S; Imanishi, T; Matsushima, K; Wada, T | 1 |
| Bell, RL; Ding, ZM; Hauser, SR; McBride, WJ; Oster, SM; Rodd, ZA; Toalston, JE | 1 |
| Asano, H; Funakami, Y; Ichida, S; Iida, T; Miyamoto, A; Nakao, M; Wada, T; Wakaki, C | 1 |
| Bell, RL; Bracken, AL; Deehan, GA; Ding, ZM; Hauser, SR; McBride, WJ; Rodd, ZA; Toalston, JE; Truitt, WA | 1 |
| du Jardin, KG; Jensen, JB; Pehrson, AL; Sanchez, C | 1 |
32 other study(ies) available for indazoles and ly 278584
| Article | Year |
|---|---|
Membrane-bound and solubilized brain 5HT3 receptors: improved radioligand binding assays using bovine area postrema or rat cortex and the radioligands 3H-GR65630, 3H-BRL43694, and 3H-LY278584.
Topics: Animals; Binding, Competitive; Brain Chemistry; Cattle; Cerebral Cortex; Chromatography, Gel; Granisetron; Imidazoles; Indazoles; Indoles; Membranes; Radioligand Assay; Rats; Receptors, Serotonin; Tropanes | 1992 |
Identification and distribution of 5-HT3 recognition sites in the rat gastrointestinal tract.
Topics: Affinity Labels; Animals; Digestive System; Female; Imidazoles; In Vitro Techniques; Indazoles; Indoles; Intestine, Small; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists; Tissue Distribution; Tritium; Tropanes | 1992 |
Localization of 5-HT3 receptors in the rat brain using [3H]LY278584.
Topics: Animals; Autoradiography; Brain Chemistry; Brain Stem; In Vitro Techniques; Indazoles; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord; Tropanes | 1991 |
Synthesis and biochemical evaluation of tritium-labeled 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxa mide, a useful radioligand for 5HT3 receptors.
Topics: Animals; Cell Membrane; Cerebral Cortex; Guinea Pigs; Heart Rate; Ileum; Indazoles; Male; Methylation; Myocardium; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Tritium; Tropanes | 1990 |
Specific [3H]LY278584 binding to 5-HT3 recognition sites in rat cerebral cortex.
Topics: Animals; Cerebral Cortex; In Vitro Techniques; Indazoles; Male; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tropanes | 1989 |
Effects of 5-HT3 receptor antagonists on binding and function of mouse and human GABAA receptors.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlorides; Flumazenil; Flunitrazepam; Humans; Indazoles; Indoles; Male; Mice; Mice, Inbred ICR; Receptors, GABA-A; Serotonin Antagonists; Tropanes; Tropisetron; Xenopus laevis | 1994 |
The subnuclear distribution of 5-HT3 receptors in the human nucleus of the solitary tract and other structures of the caudal medulla.
Topics: Adolescent; Adult; Aged; Analgesics; Antiemetics; Autoradiography; Brain Stem; Humans; Indazoles; Medulla Oblongata; Middle Aged; Receptors, Serotonin; Serotonin Antagonists; Solitary Nucleus; Substantia Gelatinosa; Tropanes | 1994 |
Serotonin 5-HT3 receptors in schizophrenia: a postmortem study of the amygdala.
Topics: Adult; Aged; Amygdala; Analysis of Variance; Animals; Autopsy; Female; Haloperidol; Hippocampus; Humans; Indazoles; Kinetics; Male; Middle Aged; Rats; Receptors, Serotonin; Reference Values; Schizophrenia; Serotonin Antagonists; Tropanes | 1993 |
Pharmacological and regional characterization of [3H]LY278584 binding sites in human brain.
Topics: Adult; Amygdala; Animals; Binding Sites; Binding, Competitive; Brain; Caudate Nucleus; Cerebral Cortex; Female; Hippocampus; Humans; Indazoles; Kinetics; Male; Organ Specificity; Putamen; Rats; Serotonin Antagonists; Tritium; Tropanes | 1993 |
5-HT3 receptor-independent inhibition of the depolarization-induced 86Rb efflux from human neuroblastoma cells, TE671, by ondansetron.
Topics: Anti-Anxiety Agents; Benzamides; Benzofurans; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; Humans; Hypoglycemic Agents; Indazoles; Indoles; Neuroblastoma; Neurotoxins; Ondansetron; Potassium Channels; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Rubidium Radioisotopes; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Tropanes; Tropisetron; Tumor Cells, Cultured | 1995 |
Molecular structure and dynamics of some potent 5-HT3 receptor antagonists. Insight into the interaction with the receptor.
Topics: Affinity Labels; Indazoles; Lipid Metabolism; Magnetic Resonance Spectroscopy; Models, Molecular; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Software; Structure-Activity Relationship; Temperature; Tropanes | 1996 |
Serotonin 5-HT3 receptor binding kinetics in the cortex of suicide victims are normal.
Topics: Adult; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Female; Humans; Hydroxyindoleacetic Acid; Indazoles; Kinetics; Male; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Suicide; Tropanes; Tryptophan | 1996 |
New 2-piperazinylbenzimidazole derivatives as 5-HT3 antagonists. Synthesis and pharmacological evaluation.
Topics: Animals; Benzimidazoles; Guinea Pigs; Indazoles; Male; Models, Chemical; Piperazines; Piperidines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Tropanes | 1997 |
5-HT is present in nerves of guinea pig sphincter of Oddi and depolarizes sphincter of Oddi neurons.
Topics: 4-Aminobenzoic Acid; 5,7-Dihydroxytryptamine; Animals; Atropine; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Evoked Potentials; Ganglia, Autonomic; Guinea Pigs; Immunohistochemistry; Indazoles; Membrane Potentials; Myenteric Plexus; Nerve Fibers; Neurons; Organ Culture Techniques; para-Aminobenzoates; Serotonin; Serotonin Antagonists; Sphincter of Oddi; Tetrodotoxin; Tropanes | 1998 |
Propulsion in guinea pig colon induced by 5-hydroxytryptamine (HT) via 5-HT4 and 5-HT3 receptors.
Topics: Animals; Benzofurans; Colon; Gastrointestinal Motility; Guinea Pigs; Humans; In Vitro Techniques; Indazoles; Indoles; Male; Piperidines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tropanes | 1999 |
Effects of repeated selective serotonin reuptake inhibitor paroxetine treatments on mouse forced swimming.
Topics: Animals; Drug Evaluation, Preclinical; Drug Interactions; Indazoles; Ketanserin; Male; Mice; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Swimming; Time Factors; Tropanes | 1999 |
The effects of continuous 5-HT(3) receptor antagonist administration on the subsequent behavioral response to cocaine.
Topics: Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Down-Regulation; Indazoles; Indoles; Infusion Pumps; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Stereotyped Behavior; Substance Withdrawal Syndrome; Tropanes; Tropisetron | 2002 |
Endogenous cannabinoid, anandamide, acts as a noncompetitive inhibitor on 5-HT3 receptor-mediated responses in Xenopus oocytes.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Arachidonic Acids; Biguanides; Cannabinoids; Chelating Agents; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electrophysiology; Endocannabinoids; Enzyme Inhibitors; Female; Indazoles; Membrane Potentials; Oocytes; Pertussis Toxin; Piperidines; Polyunsaturated Alkamides; Pyrazoles; Receptors, Serotonin, 5-HT3; Rimonabant; RNA, Complementary; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Thionucleotides; Tropanes; Xenopus laevis | 2002 |
Central 5-HT(3) receptors and water intake in rats.
Topics: Angiotensins; Animals; Autonomic Pathways; Avoidance Learning; Biguanides; Brain Chemistry; Drinking; Eating; Indazoles; Injections, Intraventricular; Male; Motor Activity; Osmolar Concentration; Parasympathetic Nervous System; Polyethylene Glycols; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes; Water Deprivation | 2002 |
Effects of serotonin-3 receptor antagonists on the intracranial self-administration of ethanol within the ventral tegmental area of Wistar rats.
Topics: Animals; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Depressants; Drug Interactions; Ethanol; Female; Indazoles; Indoles; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Self Administration; Serotonin Antagonists; Stereoisomerism; Tropanes; Tropisetron; Ventral Tegmental Area | 2003 |
Central 5-HT2B/2C and 5-HT3 receptor stimulation decreases salt intake in sodium-depleted rats.
Topics: Animals; Biguanides; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Feeding Behavior; Furosemide; Indazoles; Indoles; Injections, Intraventricular; Lithium Chloride; Male; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Saccharin; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium; Time Factors; Tropanes | 2003 |
Responses to serotonin (5HT) in isolated corpus cavernosum penis of rabbit.
Topics: 4-Aminobenzoic Acid; Animals; In Vitro Techniques; Indazoles; Male; para-Aminobenzoates; Penis; Piperazines; Pyridines; Rabbits; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Tropanes; Vasoconstriction | 2003 |
Direct activation by dopamine of recombinant human 5-HT1A receptors: comparison with human 5-HT2C and 5-HT3 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Chelating Agents; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Guanosine Diphosphate; Haloperidol; Humans; Indazoles; Inhibitory Concentration 50; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Pertussis Toxin; Piperazine; Piperazines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyridines; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT3; Recombinant Proteins; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Thionucleotides; Tropanes; Xenopus laevis | 2003 |
5-HT(3A) receptor subunit is required for 5-HT3 antagonist-induced reductions in alcohol drinking.
Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Indazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Sweetening Agents; Taste; Tropanes | 2004 |
Hyperglycemia induced by pharmacological activation of central serotonergic pathways depends on the functional integrity of brain CRH system and 5-HT3 receptors.
Topics: Animals; Blood Glucose; Corticotropin-Releasing Hormone; Hyperglycemia; Indazoles; Insulin; Male; Ondansetron; Quipazine; Rats; Rats, Wistar; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes | 2005 |
A study of the role of serotonin in the anxiolytic effect of nitrous oxide in rodents.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Cinanserin; Corpus Striatum; Dopamine; Fluoxetine; Frontal Lobe; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus; Indazoles; Male; Mice; Nitrous Oxide; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT3; Selective Serotonin Reuptake Inhibitors; Serotonin; Tropanes | 2006 |
Lack of reciprocity between opioid and 5-HT3 receptors for antinociception in rat spinal cord.
Topics: Analgesia; Analgesics, Opioid; Animals; Biguanides; Dose-Response Relationship, Drug; Formaldehyde; Hindlimb; Indazoles; Injections, Spinal; Male; Morphine; Motor Activity; Muscle Tonus; Naloxone; Narcotic Antagonists; Ondansetron; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Receptors, Serotonin, 5-HT3; Serotonin 5-HT3 Receptor Antagonists; Serotonin Receptor Agonists; Spinal Cord; Tropanes | 2006 |
Changes in characteristics of the specific binding of [3H]LY-278584, a 5-HT3-receptor antagonist, on differentiated NG108-15 cells.
Topics: Animals; Binding, Competitive; Bucladesine; Cell Differentiation; Hybrid Cells; Indazoles; Indoles; Kinetics; Mice; Nerve Tissue Proteins; Neurons; Rats; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin 5-HT3 Receptor Antagonists; Serotonin Antagonists; Tropanes; Tropisetron; Up-Regulation | 2010 |
Synergistic self-administration of ethanol and cocaine directly into the posterior ventral tegmental area: involvement of serotonin-3 receptors.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Central Nervous System Depressants; Cocaine; Conditioning, Operant; Drug Synergism; Ethanol; Female; Indazoles; Indoles; Microinjections; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT3; Self Administration; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Stereotaxic Techniques; Tropanes; Tropisetron; Ventral Tegmental Area | 2012 |
Differential expression of the 5-HT(3A) and 5-HT(3B) receptor in differentiated NG108-15 cells.
Topics: Animals; Bucladesine; Cell Differentiation; Indazoles; Mice; Protein Subunits; Rats; Receptors, Serotonin, 5-HT3; RNA, Messenger; Tropanes | 2012 |
Selective breeding for high alcohol preference increases the sensitivity of the posterior VTA to the reinforcing effects of nicotine.
Topics: Alcohol Drinking; Analysis of Variance; Animals; Benzamides; Breeding; Bridged Bicyclo Compounds, Heterocyclic; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Combinations; Female; Indazoles; Nicotine; Nicotinic Agonists; Rats, Wistar; Receptors, Serotonin, 5-HT3; Reinforcement, Psychology; Self Administration; Serotonin 5-HT3 Receptor Antagonists; Tropanes; Ventral Tegmental Area | 2014 |
Vortioxetine dose-dependently reverses 5-HT depletion-induced deficits in spatial working and object recognition memory: a potential role for 5-HT1A receptor agonism and 5-HT3 receptor antagonism.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Indazoles; Maze Learning; Memory Disorders; Memory, Short-Term; Phenylalanine; Piperazines; Protein Binding; Pyridines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Recognition, Psychology; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Sulfides; Time Factors; Tritium; Tropanes; Vortioxetine | 2014 |