Page last updated: 2024-08-21

indazoles and kainic acid

indazoles has been researched along with kainic acid in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (35.29)18.2507
2000's9 (52.94)29.6817
2010's2 (11.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, W; Penix, LP; Subramaniam, S1
Busse, R; Mordvintcev, PI; Mülsch, A; Nielsen, EO; Olesen, SP; Scheel-Krüger, J; Vanin, AF1
Carroll, DM; Grossman, AB; Kirkby, RD; Subramaniam, S1
Jones, PA; Smith, RA; Stone, TW1
Carrasco, V; Durland, WF; Johnson, KL; Pillsbury, HC; Prazma, J; Zdanski, CJ1
Alabadí, JA; Lasbennes, F; Pinard, E; Seylaz, J; Thibault, JL1
Camarasa, J; Camins, A; Escubedo, E; Friguls, B; Gabriel, C; Pallas, M; Planas, AM; Sureda, FX1
Fujii, M; Fujisawa, H; Ito, H; Suzuki, M; Yasuda, H1
Che, Y; Han, PL; Lee, JK; Piao, CS1
Cespedes, GC; Cubeddu, LX; Guevara, BH1
Dettbarn, WD; Gupta, RC1
Chen, J; Li, C; Zhang, S1
Jovanovic, M; Radenovic, L; Selakovic, V; Vasiljevic, I1
Fu, YS; Huang, YH; Ko, MH; Lee, AW; Shih, YH1
Bouilleret, V; de Vasconcelos, AP; Nehlig, A; Riban, V; Wasterlain, C1
Cosgrave, AS; McKay, JS; Thippeswamy, T1
Allegra, M; Bozzi, Y; Caleo, M; Cerri, C; Genovesi, S; Guglielmotti, A; Perry, VH; Pistillo, F; Püntener, U1

Other Studies

17 other study(ies) available for indazoles and kainic acid

ArticleYear
Inhibition of NO synthase increases the severity of kainic acid-induced seizures in rodents.
    Epilepsy research, 1994, Volume: 18, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Bicuculline; Cerebrovascular Circulation; Enzyme Inhibitors; Indazoles; Kainic Acid; Male; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures

1994
Nitric oxide promotes seizure activity in kainate-treated rats.
    Neuroreport, 1994, Nov-21, Volume: 5, Issue:17

    Topics: Amino Acid Oxidoreductases; Animals; Diazepam; Ditiocarb; Indazoles; Iron; Kainic Acid; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar; Seizures

1994
Factors determining proconvulsant and anticonvulsant effects of inhibitors of nitric oxide synthase in rodents.
    Epilepsy research, 1996, Volume: 24, Issue:2

    Topics: Animals; Anticonvulsants; Behavior, Animal; Convulsants; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Indazoles; Kainic Acid; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Picrotoxin; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Species Specificity

1996
Nitric oxide synthase inhibitors L-NAME and 7-nitroindazole protect rat hippocampus against kainate-induced excitotoxicity.
    Neuroscience letters, 1998, Jun-19, Volume: 249, Issue:2-3

    Topics: Analysis of Variance; Animals; Hippocampus; Indazoles; Injections, Intraperitoneal; Kainic Acid; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar

1998
Role of nitric oxide in kainic acid-induced elevation of cochlear compound action potential thresholds.
    Acta oto-laryngologica, 1998, Volume: 118, Issue:5

    Topics: Action Potentials; Analysis of Variance; Animals; Cochlear Microphonic Potentials; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gerbillinae; Indazoles; Kainic Acid; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Perfusion; Time Factors

1998
7-Nitroindazole, a selective inhibitor of nNOS, increases hippocampal extracellular glutamate concentration in status epilepticus induced by kainic acid in rats.
    Brain research, 1999, Aug-28, Volume: 839, Issue:2

    Topics: Animals; Arginine; Chromatography, High Pressure Liquid; Citrulline; Electroencephalography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Space; Glutamic Acid; Hippocampus; Indazoles; Kainic Acid; Male; Microdialysis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Rats; Rats, Wistar; Status Epilepticus; Synaptic Transmission

1999
Inhibitors of NO-synthase and donors of NO modulate kainic acid-induced damage in the rat hippocampus.
    Journal of neuroscience research, 2000, Mar-15, Volume: 59, Issue:6

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Heat-Shock Proteins; Hippocampus; HSP72 Heat-Shock Proteins; Indazoles; Intracellular Signaling Peptides and Proteins; Isoquinolines; Kainic Acid; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Protein Serine-Threonine Kinases; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

2000
Changes in nitric oxide synthesis and epileptic activity in the contralateral hippocampus of rats following intrahippocampal kainate injection.
    Epilepsia, 2001, Volume: 42, Issue:1

    Topics: Animals; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Epilepsy; Functional Laterality; Hippocampus; Indazoles; Injections, Intraperitoneal; Kainic Acid; Male; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar

2001
Delayed induction of alpha B-crystallin in activated glia cells of hippocampus in kainic acid-treated mouse brain.
    Journal of neuroscience research, 2001, Sep-01, Volume: 65, Issue:5

    Topics: Animals; Arginine; Astrocytes; Crystallins; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gliosis; Heat-Shock Proteins; Hippocampus; Immunohistochemistry; Indazoles; Kainic Acid; Male; Mice; Mice, Inbred BALB C; Molecular Chaperones; Neoplasm Proteins; Nerve Degeneration; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Seizures

2001
Treatment with 7-nitroindazole enhances kainic acid induced cholinergic neurotoxicity in the rat striatum: a neuroprotective role for neuronal nitric oxide.
    Cellular and molecular neurobiology, 2002, Volume: 22, Issue:5-6

    Topics: Animals; Cell Death; Choline O-Acetyltransferase; Cholinergic Fibers; Drug Synergism; Enzyme Inhibitors; Indazoles; Kainic Acid; Neostriatum; Nerve Degeneration; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Up-Regulation

2002
Prevention of kainic acid seizures-induced changes in levels of nitric oxide and high-energy phosphates by 7-nitroindazole in rat brain regions.
    Brain research, 2003, Aug-15, Volume: 981, Issue:1-2

    Topics: Amygdala; Animals; Brain; Brain Chemistry; Cerebral Cortex; Citrulline; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Indazoles; Kainic Acid; Male; Nitric Oxide; Phosphates; Rats; Rats, Sprague-Dawley; Status Epilepticus; Time Factors

2003
[Role of nitric oxide in excitotoxicity and memory impairment induced by kainic acid].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2000, Volume: 22, Issue:3

    Topics: Animals; Enzyme Inhibitors; Female; Indazoles; Kainic Acid; Memory Disorders; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Wistar

2000
7-nitroindazole reduces nitrite concentration in rat brain after intrahippocampal kainate-induced seizure.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2003, Volume: 135, Issue:4

    Topics: Animals; Anticonvulsants; Brain; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Indazoles; Kainic Acid; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitrites; Rats; Rats, Wistar; Seizures; Time Factors

2003
GABAergic neuron death in the striatum following kainate-induced damage of hippocampal neurons: evidence for the role of NO in locomotion.
    The International journal of neuroscience, 2004, Volume: 114, Issue:9

    Topics: Animals; Cell Death; Denervation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; gamma-Aminobutyric Acid; Hippocampus; Indazoles; Kainic Acid; Motor Activity; Neostriatum; Neural Pathways; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyramidal Cells; Rats; Rats, Sprague-Dawley

2004
Role of nitric oxide in cerebral blood flow changes during kainate seizures in mice: genetic and pharmacological approaches.
    Neurobiology of disease, 2005, Volume: 18, Issue:2

    Topics: Animals; Antipyrine; Brain; Cerebral Cortex; Cerebrovascular Circulation; Convulsants; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Epilepsy; Functional Laterality; Hippocampus; Indazoles; Kainic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Status Epilepticus

2005
Differential regulation of vasoactive intestinal peptide (VIP) in the dentate gyrus and hippocampus via the NO-cGMP pathway following kainic acid-induced seizure in the rat.
    Journal of molecular neuroscience : MN, 2010, Volume: 42, Issue:3

    Topics: Animals; Cyclic GMP; Dentate Gyrus; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Guanylate Cyclase; Hippocampus; Indazoles; Kainic Acid; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Vasoactive Intestinal Peptide

2010
The Chemokine CCL2 Mediates the Seizure-enhancing Effects of Systemic Inflammation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, Mar-30, Volume: 36, Issue:13

    Topics: Animals; Antibodies; Benzoxazines; Chemokine CCL2; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Excitatory Amino Acid Agonists; Hippocampus; Indazoles; Inflammation; Kainic Acid; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Piperidines; Propionates; Receptors, CCR2; RNA, Messenger; Signal Transduction; Up-Regulation

2016