Page last updated: 2024-08-21

indazoles and isomethyleugenol

indazoles has been researched along with isomethyleugenol in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's2 (13.33)18.2507
2000's0 (0.00)29.6817
2010's9 (60.00)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Bruneau, P; Delvare, C; Edwards, MP; McMillan, RM1
Bloomquist, W; Cohen, ML; Reid, LR; Robertson, DW; Schenck, K; Wong, DT1
Okamoto, HS; Vance, WA; Wang, YY1
Allain, CJ; Chesworth, R; Copeland, RA; Jin, L; Keilhack, H; Klaus, CR; Knutson, SK; Kuntz, KW; Majer, CR; Moyer, MP; Olhava, EJ; Pollock, RM; Raimondi, A; Richon, VM; Sacks, JD; Scott, MP; Smith, JJ; Sneeringer, CJ; Song, J; Warholic, NM; Wigle, TJ1
Abrams, JS; Conley, BA; Freidlin, B; Korn, EL; McShane, LM; Polley, MY1
Cao, JJ; Chen, D; DU, XH; Li, SY; Liu, XH; Ma, JX; Pei, RZ; Sha, KY; Tang, SH; Zhang, PS1
Archin, NM; Burch, BD; Margolis, DM; McManamy, ME; Tripathy, MK1
Biron, VL; Harris, J; Kostiuk, MA; Lindsay, CD; O'Connell, DA; Seikaly, H1
Bulic, M; Dupéré-Richer, D; Ezponda, T; Huang, X; Keats, J; Kelleher, N; Licht, JD; Maji, S; Nabet, B; Occhionorelli, M; Oyer, J; Patel, T; Popovic, R; Riva, A; Shah, MY; Small, EC; Tonon, G; Varghese, N; Will, CM; Zheng, Y1
Boblewski, K; Kornicka, A; Lehmann, A; Marchwinska, A; Rybczynska, A; Saczewski, F; Wasilewska, A1
Feng, L; Hong, F; Zhang, L; Zhao, M1
Huang, J; Huang, S; Li, QJ; Long, H; Symonds, ALJ; Tang, X; Wan, YY; Wang, Z; Xu, L; Zhou, J; Zhu, B1
Gildenhuys, S; Magwaza, NM; Mphahlele, MJ; Setshedi, IB1
Damle, M; Kim, J; Kingston, RE; Miller, SA1
Li, Y; Wang, X; Yan, H; Yin, J; Yu, M1

Other Studies

15 other study(ies) available for indazoles and isomethyleugenol

ArticleYear
Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Administration, Oral; Animals; Chemical Phenomena; Chemistry; Dinoprostone; Dogs; Humans; Indazoles; Leukotriene B4; Lipoxygenase Inhibitors; Male; Methemoglobinemia; Methylation; Molecular Structure; Oxidation-Reduction; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship; Thromboxane B2

1991
Synthesis and biochemical evaluation of tritium-labeled 1-methyl-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-1H-indazole-3-carboxa mide, a useful radioligand for 5HT3 receptors.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:12

    Topics: Animals; Cell Membrane; Cerebral Cortex; Guinea Pigs; Heart Rate; Ileum; Indazoles; Male; Methylation; Myocardium; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Tritium; Tropanes

1990
Structure-activity relationships of nitro and methyl-nitro derivatives of indoline, indole, indazole and benzimidazole in Salmonella typhimurium.
    Mutation research, 1986, Volume: 173, Issue:3

    Topics: Benzimidazoles; Imidazoles; Indazoles; Indoles; Methylation; Mutagenicity Tests; Nitro Compounds; Pyrazoles; Salmonella typhimurium; Structure-Activity Relationship

1986
A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells.
    Nature chemical biology, 2012, Volume: 8, Issue:11

    Topics: Antineoplastic Agents; Cell Cycle; Cell Death; Cell Proliferation; Dose-Response Relationship, Drug; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Histones; Humans; Indazoles; Lymphoma; Lysine; Methylation; Molecular Structure; Point Mutation; Polycomb Repressive Complex 2; Pyridones; Structure-Activity Relationship

2012
Statistical and practical considerations for clinical evaluation of predictive biomarkers.
    Journal of the National Cancer Institute, 2013, Nov-20, Volume: 105, Issue:22

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; ErbB Receptors; Gefitinib; Glioblastoma; Humans; Indazoles; Interleukin-6; Kidney Neoplasms; Lung Neoplasms; Methylation; Molecular Targeted Therapy; Mutation; Neoplasms; Precision Medicine; Predictive Value of Tests; Pyrimidines; Quinazolines; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Sample Size; Sulfonamides; Temozolomide; Tumor Suppressor Proteins

2013
[Effects of H3K27 methylation inhibitor EPZ005687 on apoptosis, proliferation and cell cycle of U937 cells and normal CD34 positive cells].
    Zhongguo shi yan xue ye xue za zhi, 2014, Volume: 22, Issue:6

    Topics: Antigens, CD34; Apoptosis; Cell Cycle; Cell Proliferation; Humans; Indazoles; Methylation; Pyridones; U937 Cells

2014
H3K27 Demethylation at the Proviral Promoter Sensitizes Latent HIV to the Effects of Vorinostat in Ex Vivo Cultures of Resting CD4+ T Cells.
    Journal of virology, 2015, Volume: 89, Issue:16

    Topics: Analysis of Variance; CD4-Positive T-Lymphocytes; Chromatin Immunoprecipitation; Enhancer of Zeste Homolog 2 Protein; Enzyme-Linked Immunosorbent Assay; Histones; HIV; Humans; Hydroxamic Acids; Immunoblotting; Indazoles; Methylation; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Proviruses; Pyridones; RNA, Small Interfering; Vorinostat

2015
Efficacy of EZH2 inhibitory drugs in human papillomavirus-positive and human papillomavirus-negative oropharyngeal squamous cell carcinomas.
    Clinical epigenetics, 2017, Volume: 9

    Topics: Carcinoma, Squamous Cell; Cell Line, Tumor; Cyclin D1; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; ErbB Receptors; Gene Expression Regulation, Neoplastic; Histones; Humans; Indazoles; Methylation; Oropharyngeal Neoplasms; Papillomavirus Infections; Pyridones

2017
UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition.
    Cell reports, 2017, Oct-17, Volume: 21, Issue:3

    Topics: Animals; Carcinogenesis; Cell Adhesion; Cell Dedifferentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Clone Cells; Enhancer of Zeste Homolog 2 Protein; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Demethylases; Histones; Indazoles; Interferon Regulatory Factors; Lysine; Methylation; Mice; Mice, Inbred NOD; Mice, SCID; Multiple Myeloma; Mutation; Nuclear Proteins; Phenotype; Pyridones; Transcription, Genetic

2017
COMPARISON OF THE EFFECTS OF MARSANIDINE DERIVATIVES ON RAT CARDIOVASCULAR SYSTEM.
    Acta poloniae pharmaceutica, 2017, Volume: 74, Issue:2

    Topics: Animals; Antihypertensive Agents; Arterial Pressure; Cardiovascular System; Diuresis; Halogenation; Heart Rate; Imidazolidines; Indazoles; Male; Methylation; Molecular Structure; Rats, Wistar; Structure-Activity Relationship; Time Factors

2017
Inhibition of Ezh2 In Vitro and the Decline of
    Stem cells and development, 2019, 05-15, Volume: 28, Issue:10

    Topics: Animals; Cell Differentiation; Cells, Cultured; Dopaminergic Neurons; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Histone Deacetylase Inhibitors; Histones; Indazoles; Lysine; Mesencephalon; Methylation; Neural Stem Cells; Nuclear Receptor Subfamily 4, Group A, Member 2; Promoter Regions, Genetic; Pyridones; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Tyrosine 3-Monooxygenase

2019
Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation.
    Nature communications, 2019, 06-03, Volume: 10, Issue:1

    Topics: Animals; Cell Differentiation; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Female; Hematopoietic Stem Cells; Histone Code; Histones; In Vitro Techniques; Indazoles; Indoles; Inflammatory Bowel Diseases; Methylation; Mice; Myeloid-Derived Suppressor Cells; Pyridones

2019
Synthesis, α-glucosidase inhibition and antioxidant activity of the 7-carbo-substituted 5-bromo-3-methylindazoles.
    Bioorganic chemistry, 2020, Volume: 97

    Topics: alpha-Glucosidases; Antioxidants; Glycoside Hydrolase Inhibitors; Halogenation; HEK293 Cells; Humans; Indazoles; MCF-7 Cells; Methylation; Molecular Docking Simulation; Structure-Activity Relationship

2020
Full methylation of H3K27 by PRC2 is dispensable for initial embryoid body formation but required to maintain differentiated cell identity.
    Development (Cambridge, England), 2021, 04-01, Volume: 148, Issue:7

    Topics: Animals; Cell Differentiation; Cell Line; Embryoid Bodies; Embryonic Stem Cells; Enhancer of Zeste Homolog 2 Protein; Histones; Indazoles; Lysine; Methylation; Mice; Phenotype; Polycomb Repressive Complex 2; Protein Processing, Post-Translational; Pyridones; Transcriptome

2021
Enhanced Calcium Signal Induces NK Cell Degranulation but Inhibits Its Cytotoxic Activity.
    Journal of immunology (Baltimore, Md. : 1950), 2022, 01-15, Volume: 208, Issue:2

    Topics: Benzamides; Calcium; Calcium Signaling; Cell Degranulation; Cell Line; Enhancer of Zeste Homolog 2 Protein; Histones; Humans; Indazoles; Killer Cells, Natural; Lymphocyte Activation; Methylation; Piperazines; Pyridones; TRPP Cation Channels

2022