Page last updated: 2024-08-21

indazoles and granisetron

indazoles has been researched along with granisetron in 117 studies

Research

Studies (117)

Timeframe	Studies, this research(%)	All Research%
pre-1990	16 (13.68)	18.7374
1990's	101 (86.32)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Airey, JE; Campbell, HF; Darkes, P; Fitzpatrick, LR; Klein, S; Neuenschwander, K; Pendley, CE; Powers, M; Schnapper, M; Youssefyeh, RD	1
Aguerri, MF; Alby, N; Giacchetti, S; Imbeaux, PH	1
Fletcher, PW; Miller, K; Teitler, M; Weisberg, E	1
Bremer, K	1
Marty, M	2
Blijham, GH	1
Andrews, PL; Bhandari, P; Bingham, S; Blower, PR; Davey, PT; Marr, HE	1
Diehl, V	1
Hacking, A	1
Dilly, S	1
Kamanabrou, D	1
Fell, GL; Leigh, TJ; Link, CG	3
Ashby, CR; Minabe, Y; Wang, RY	1
Andrews, PL; Bingham, S; Joel, SP; Patel, N; Slevin, ML; Thompson, PI	1
Sakamori, M; Setoguchi, M; Takehara, S	1
Blijham, GH; Bots, MW; Dijkstra, HJ; Fehmers, MC; Keizer, HJ; Nortier, JW; Siegenbeek van Heukelom, L; Slee, PH; van der Wall, E; Veenhof, CH	1
Kaizer, L; Laberge, F; Latreille, J; O'Connell, G; Osoba, D; Pater, J; Stewart, D; Venner, P; Warr, D; Wilan, A	1
Bosanquet, N; Jones, AL; Lee, GJ	1
Cassuto, J; Jodal, M; Lundgren, O; Sjöqvist, A	1
Barnes, NM; Cheng, CH; Costall, B; Ge, J; Kelly, ME; Naylor, RJ	1
Aapro, M; Diehl, V; Kaye, SB; Khayat, D	1
Choudry, NB; Fuller, RW; Lavender, EA; McEwan, JR; Williams, AJ	1
Cutler, MG	2
Soukop, M	2
Clifford Rose, F; Couturier, EG; Foster, CA; Hering, R; Steiner, TJ	1
Butler, M; Collis, C; Coumar, A; Gandhi, L; Hamon, M; Hunter, AE; Murdoch, R; Pothecary, K; Prentice, HG; Upward, J	1
Davis, A; Erlichman, C; Fine, S; Laberge, F; Lofters, W; Osoba, D; Rusthoven, J; Warr, D; Willan, A; Wilson, K	1
Smith, RA	1
Bernardi, M; Di Sarra, B; Montecchiani, G; Re, L; Rossini, L; Tonnini, C	1
Ito, H; Iwai, A; Kamato, T; Katsuyama, Y; Miyata, K; Nishida, A; Ohta, M; Tsutsumi, R; Yamano, M; Yuki, H	1
Hunter, RD; Logue, JP; Magee, B; Murdoch, RD	1
Amaral, D; Lemerle, J; Murdoch, RD; Southall, DP; Upward, J	1
Bremer, K; Uhlenbusch, R	1
Davis, A; Merrill, CF; Rowat, BM; South, V	1
Andrews, PL; Bhandari, P	1
Higgins, GA; Jones, BJ; Oakley, NR; Tyers, MB	1
de Mulder, PH; Seynaeve, C; Verweij, J	1
Chugh, Y; Saha, N; Sankaranarayanan, A; Sharma, PL	1
Ashby, CR; Minabe, Y; Schwartz, JE; Wang, RY	1
Barber, NA; Grahame-Smith, DG; Leslie, RA; Reynolds, DJ	1
Brown, NJ; French, SJ; Read, NW; Rumsey, RD	1
Gamse, R; Humpel, C; Javorsky, F; Saria, A	2
Anderson, I; Cowen, P	1
Goa, KL; Plosker, GL	1
Itoh, Z; Iwanaga, Y; Mizumoto, A; Yoshida, N	1
Itoh, Z; Iwanaga, Y; Mizumoto, A; Torii, K; Wakabayashi, K; Yoshida, N	1
Gandara, DR; Hesketh, PJ	1
Falkson, CI; Falkson, G; Falkson, HC	1
Barnes, NM; Costall, B; Kelly, ME; Naylor, RJ; Onaivi, ES	1
Ito, S	1
Costall, B; Domeney, AM; Naylor, RJ	1
Addelman, M; Erlichman, C; Fine, S; Murray, C; Warr, D	1
Goddard, PM; Harrap, KR; Jones, M; Pollard, LA; Valenti, MR	1
Ashby, CR; Jiang, LH; Wang, RY	1
Nakao, I	1
Cutler, MG; Piper, DC	1
King, GL	1
Airey, JE; Bostwick, JS; Decktor, DL; Fitzpatrick, LR; Gessner, GW; Lambert, RM; Martin, GE; Pendleton, RG; Pendley, CE; Youssefyeh, RD	1
Moss, HE; Sanger, GJ	1
Elliott, P; Wallis, DI	1
Elliott, P; Seemungal, BM; Wallis, DI	1
Allen, A; Arnold, BD; Link, C; Pierce, DM; Tasker, TC; Upward, JW	1
Smith, IE	2
Brand, BC; Buser, KS; Cerny, T; Joss, RA	1
Caubel, M; Cupissol, DR; Serrou, B	1
Chevallier, B	2
Tabona, MV	1
Blower, PR	1
Andrews, PL; Davis, CJ; Grahame-Smith, DG; Harvey, JM; Leslie, RA; Reynolds, DJ	1
Pintens, H	1
Brown, GW; Butcher, ME; Kidgell, AE	1
Maher, M	1
Button, D	1
Smit, P	1
Chen, HI	1
Nelson, DR; Sanger, GJ	1
Cantwell, BM; Carmichael, J; Edwards, CM; Harris, AL; Rapeport, WG; Thompson, S; Zussman, BD	1
Nelson, DR; Thomas, DR	1
Falkson, G; van Zyl, AJ	1
Bhandari, P; Gupta, YK; Seth, SD	1
Brunner, K; Buser, K; Joss, R; Karde, C; Pirovino, M; Rohrbach, D	1
File, SE; Johnston, AL	1
Bowery, NG; Pratt, GD	1
Ashby, CR; Edwards, E; Harkins, K; Wang, RY	1
Ito, A; Ito, T; Iwanaga, H; Karasawa, T; Mizumoto, A; Yoshida, N	1
Cantwell, BM; Carmichael, J; Edwards, CM; Harris, AL; Rapeport, WG	1
Brunner, KW; Joss, RA; Pirovino, M; Richner, J; Rohrbach, D; Terrey, JP; Upward, J	1
Bermudez, J; Boyle, EA; Miner, WD; Sanger, GJ	1
Adams, L; Cassidy, J; Kaye, SB; Lewis, C; Raina, V; Rankin, EM; Rapeport, WG; Soukop, M; Zussman, BD	1
Barnes, NM; Costall, B; Naylor, RJ; Tattersall, FD	1
Blauw, GJ; Bruning, TA; Chang, PC; van Zwieten, PA; Vermeij, P	1
Brown, NJ; Horton, A; Read, NW; Rumsey, RD	1
Dott, CS; Joss, RA	1
Grahame-Smith, DG; Leslie, RA; Pei, Q; Zetterström, T	1
Angel, I; Garreau, M; Langer, SZ; Prouteau, M; Schoemaker, H	1
Prior, A; Read, NW	1
de Wet, M; Falkson, G; Rapoport, BL	1
Fukunaka, N; Ishioka, S; Itoh, E; Kitajima, Y; Kudo, R; Sagae, S; Sato, K	1
Barnes, JM; Barnes, NM	1
Snyman, JR; Sommers, DK; van Wyk, M	1
Furue, H; Niitani, H; Ogawa, N; Ohta, K; Suminaga, M; Taguchi, T	2
Gondo, H; Harada, M; Matsuishi, H; Omori, F; Otsuka, T; Shibuya, T; Taniguchi, S; Teshima, T; Yamano, Y; Yamazaki, K	1
Aapro, MS	1
Hiraoka, A; Kageyama, T; Kakishita, E; Masaoka, T; Matsuzawa, Y; Nagai, K; Okuda, K; Oshiba, S; Tatsumi, N; Uchino, H	1
Mori, K; Suga, Y; Takahashi, T; Tominaga, K	1

Reviews

10 review(s) available for indazoles and granisetron

Article	Year
Are granisetron and ondansetron equivalent in the clinic? European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A Suppl 1 Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Granisetron; Humans; Imidazoles; Indazoles; Nausea; Ondansetron; Serotonin Antagonists; Vomiting	1992
5-hydroxytryptamine-3 antagonists: a new class of potent antiemetics in cancer therapy. Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1991, Volume: 121 Topics: Animals; Antiemetics; Granisetron; Humans; Imidazoles; Indazoles; Ondansetron; Serotonin Antagonists	1991
5-HT3 receptor antagonists, a new approach in emesis: a review of ondansetron, granisetron and tropisetron. Anti-cancer drugs, 1991, Volume: 2, Issue:4 Topics: Animals; Antiemetics; Granisetron; Humans; Imidazoles; Indazoles; Indoles; Ondansetron; Serotonin Antagonists; Tropisetron; Vomiting	1991
Granisetron. A review of its pharmacological properties and therapeutic use as an antiemetic. Drugs, 1991, Volume: 42, Issue:5 Topics: Animals; Antiemetics; Antineoplastic Agents; Female; Granisetron; Humans; Indazoles; Male; Nausea; Neoplasms; Serotonin Antagonists; Vomiting	1991
[Gastrointestinal side effects of anticancer agents and their counter measures]. Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:4 Pt 2 Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Granisetron; Humans; Indazoles; Nausea; Vomiting	1990
Granisetron (BRL 43694) in the treatment of cytostatic drug-induced emesis: a summary. Cancer treatment reviews, 1990, Volume: 17, Issue:2-3 Topics: Animals; Antiemetics; Antineoplastic Agents; Cisplatin; Ferrets; Granisetron; Headache; Humans; Indazoles; Serotonin Antagonists; Vomiting	1990
Antiemetic control: 5-HT3 antagonists: review of clinical results, with particular emphasis on ondansetron. Cancer treatment reviews, 1990, Volume: 17, Issue:2-3 Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Granisetron; Headache; Humans; Imidazoles; Indazoles; Indoles; Nausea; Ondansetron; Radiation Injuries; Radiotherapy; Serotonin Antagonists; Tropisetron; Vomiting	1990
Recent developments in the management of emesis with the 5-HT3 antagonist granisetron. Seminars in oncology nursing, 1990, Volume: 6, Issue:4 Suppl 1 Topics: Antiemetics; Granisetron; Humans; Indazoles; Serotonin Antagonists; Vomiting	1990
Future prospects for granisetron. Seminars in oncology nursing, 1990, Volume: 6, Issue:4 Suppl 1 Topics: Antiemetics; Granisetron; Humans; Indazoles	1990
Review of experience with ondansetron and granisetron. Annals of oncology : official journal of the European Society for Medical Oncology, 1993, Volume: 4 Suppl 3 Topics: Antiemetics; Antineoplastic Agents; Granisetron; Humans; Indazoles; Nausea; Ondansetron; Serotonin Antagonists; Vomiting	1993

Trials

32 trial(s) available for indazoles and granisetron

Article	Year
A single-blind study of the efficacy and safety of intravenous granisetron compared with alizapride plus dexamethasone in the prophylaxis and control of emesis in patients receiving 5-day cytostatic therapy. The Granisetron Study Group. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:6-7 Topics: Adult; Antiemetics; Antineoplastic Agents; Dexamethasone; Drug Therapy, Combination; Female; Granisetron; Humans; Indazoles; Infusions, Intravenous; Male; Middle Aged; Nausea; Pyrrolidines; Single-Blind Method; Vomiting	1992
A comparison of granisetron as a single agent with conventional combination antiemetic therapies in the treatment of cytostatic-induced emesis. The Granisetron Study Group. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A Suppl 1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Cisplatin; Drug Therapy, Combination; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Single-Blind Method; Vomiting	1992
Fractionated chemotherapy--granisetron or conventional antiemetics? The Granisetron Study Group. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A Suppl 1 Topics: Adult; Antiemetics; Antineoplastic Agents; Dexamethasone; Drug Administration Schedule; Drug Therapy, Combination; Female; Granisetron; Humans; Indazoles; Male; Metoclopramide; Middle Aged; Nausea; Pyrrolidines; Single-Blind Method; Vomiting	1992
Oral granisetron--simple and effective: a preliminary report. The Granisetron Study Group. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A Suppl 1 Topics: Administration, Oral; Adult; Antiemetics; Antineoplastic Agents; Double-Blind Method; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Vomiting	1992
Intravenous granisetron--establishing the optimal dose. The Granisetron Study Group. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A Suppl 1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Double-Blind Method; Drug Administration Schedule; Female; Granisetron; Humans; Indazoles; Infusions, Intravenous; Male; Middle Aged; Nausea; Vomiting	1992
Effects of granisetron and haloperidol, alone and in combination, on psychometric performance and the EEG. British journal of clinical pharmacology, 1992, Volume: 34, Issue:1 Topics: Adult; Drug Interactions; Electroencephalography; Granisetron; Haloperidol; Humans; Indazoles; Male; Psychometrics; Psychomotor Performance; Random Allocation; Serotonin Antagonists	1992
A randomized trial of two doses of granisetron in the treatment of chemotherapy-induced emesis. Dutch results within a multinational study. The Netherlands journal of medicine, 1992, Volume: 40, Issue:5-6 Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Antineoplastic Agents; Cisplatin; Dose-Response Relationship, Drug; Double-Blind Method; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Netherlands; Serotonin Antagonists; Vomiting	1992
A randomised, double-blind comparison of granisetron with high-dose metoclopramide, dexamethasone and diphenhydramine for cisplatin-induced emesis. An NCI Canada Clinical Trials Group Phase III Trial. European journal of cancer (Oxford, England : 1990), 1992, Volume: 29A, Issue:1 Topics: Antiemetics; Cisplatin; Dexamethasone; Diphenhydramine; Double-Blind Method; Drug Therapy, Combination; Female; Granisetron; Humans; Indazoles; Male; Metoclopramide; Middle Aged; Nausea; Vomiting	1992
Effects of granisetron and lorazepam, alone and in combination, on psychometric performance. British journal of clinical pharmacology, 1991, Volume: 31, Issue:3 Topics: Adult; Drug Interactions; Flicker Fusion; Granisetron; Humans; Indazoles; Lorazepam; Male; Mental Processes; Middle Aged; Psychometrics; Psychomotor Performance; Reaction Time; Serotonin Antagonists; Single-Blind Method; Time Perception	1991
Human responses to inhaled capsaicin are not inhibited by granisetron. British journal of clinical pharmacology, 1991, Volume: 31, Issue:3 Topics: Administration, Inhalation; Adult; Airway Resistance; Capsaicin; Cough; Granisetron; Humans; Indazoles; Male; Reflex; Serotonin Antagonists	1991
First clinical study of the selective 5-HT3 antagonist, granisetron (BRL 43694), in the acute treatment of migraine headache. Headache, 1991, Volume: 31, Issue:5 Topics: Adult; Granisetron; Humans; Indazoles; Infusions, Intravenous; Middle Aged; Migraine Disorders; Serotonin Antagonists	1991
Superiority of granisetron to dexamethasone plus prochlorperazine in the prevention of chemotherapy-induced emesis. Journal of the National Cancer Institute, 1991, Aug-21, Volume: 83, Issue:16 Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Prochlorperazine; Serotonin Antagonists; Vomiting	1991
The antiemetic effect of granisetron in lower hemibody radiotherapy. Clinical oncology (Royal College of Radiologists (Great Britain)), 1991, Volume: 3, Issue:5 Topics: Aged; Antiemetics; Bone Neoplasms; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Prospective Studies; Radiotherapy; Vomiting	1991
[Comparison of the antiemetic effectiveness of granisetron and alizapride plus dexamethasone in cytostatic therapy]. Deutsche medizinische Wochenschrift (1946), 1991, Nov-29, Volume: 116, Issue:48 Topics: Adult; Aged; Aged, 80 and over; Antiemetics; Cisplatin; Dexamethasone; Drug Therapy, Combination; Etoposide; Female; Granisetron; Humans; Ifosfamide; Indazoles; Male; Middle Aged; Neoplasms; Pyrrolidines; Serotonin Antagonists; Single-Blind Method	1991
A double-blind comparison of granisetron and placebo for the treatment of acute migraine in the emergency department. Cephalalgia : an international journal of headache, 1991, Volume: 11, Issue:5 Topics: Acute Disease; Adult; Double-Blind Method; Emergency Service, Hospital; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Migraine Disorders; Placebos; Serotonin Antagonists	1991
Granisetron. A review of its pharmacological properties and therapeutic use as an antiemetic. Drugs, 1991, Volume: 42, Issue:5 Topics: Animals; Antiemetics; Antineoplastic Agents; Female; Granisetron; Humans; Indazoles; Male; Nausea; Neoplasms; Serotonin Antagonists; Vomiting	1991
Effects of granisetron and lorazepam, alone and in combination, on the EEG of human volunteers. British journal of clinical pharmacology, 1991, Volume: 31, Issue:1 Topics: Adult; Double-Blind Method; Drug Interactions; Electroencephalography; Granisetron; Humans; Indazoles; Lorazepam; Male; Middle Aged; Random Allocation; Serotonin Antagonists	1991
High versus low dose granisetron, a selective 5HT3 antagonist, for the prevention of chemotherapy-induced nausea and vomiting. Investigational new drugs, 1990, Volume: 8, Issue:4 Topics: Antineoplastic Agents; Double-Blind Method; Drugs, Investigational; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Random Allocation; Serotonin Antagonists; Vomiting	1990
The clinical pharmacology of granisetron (BRL 43694), a novel specific 5-HT3 antagonist. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26 Suppl 1 Topics: Blood Pressure; Constipation; Dose-Response Relationship, Drug; Electrocardiography; Granisetron; Half-Life; Humans; Indazoles; Psychomotor Performance; Pulse; Receptors, Serotonin; Serotonin Antagonists	1990
A comparison of two dose levels of granisetron in patients receiving high-dose cisplatin. The Granisetron Study Group. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26 Suppl 1 Topics: Cisplatin; Double-Blind Method; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Neoplasms; Serotonin Antagonists; Time Factors; Vomiting	1990
A comparison of two dose levels of granisetron in patients receiving moderately emetogenic cytostatic chemotherapy. The Granisetron Study Group. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26 Suppl 1 Topics: Antineoplastic Agents; Double-Blind Method; Female; Granisetron; Headache; Humans; Indazoles; Male; Middle Aged; Nausea; Serotonin Antagonists; Time Factors; Vomiting	1990
The efficacy of granisetron as a prophylactic anti-emetic and intervention agent in high-dose cisplatin-induced emesis. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26 Suppl 1 Topics: Adult; Aged; Cisplatin; Double-Blind Method; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Neoplasms; Serotonin Antagonists; Sex Factors; Time Factors; Vomiting	1990
A comparative study of the use of granisetron, a selective 5-HT3 antagonist, versus a standard anti-emetic regimen of chlorpromazine plus dexamethasone in the treatment of cytostatic-induced emesis. The Granisetron Study Group. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26 Suppl 1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chlorpromazine; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Serotonin Antagonists; Time Factors; Vomiting	1990
Efficacy and safety of granisetron compared with high-dose metoclopramide plus dexamethasone in patients receiving high-dose cisplatin in a single-blind study. The Granisetron Study Group. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26 Suppl 1 Topics: Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; Granisetron; Headache; Humans; Indazoles; Male; Metoclopramide; Middle Aged; Neoplasms; Serotonin Antagonists; Single-Blind Method; Vomiting	1990
A dose-finding study of granisetron, a novel antiemetic, in patients receiving cytostatic chemotherapy. The Granisetron Study Group. Journal of cancer research and clinical oncology, 1993, Volume: 119, Issue:6 Topics: Antiemetics; Antineoplastic Agents; Double-Blind Method; Female; Granisetron; Humans; Indazoles; Infant, Newborn; Injections, Intravenous; Nausea; Vomiting	1993
Effect of metoclopramide, ondansetron and granisetron on aldosterone secretion in man. European journal of clinical pharmacology, 1993, Volume: 44, Issue:4 Topics: Adult; Aldosterone; Granisetron; Humans; Indazoles; Male; Metoclopramide; Ondansetron; Receptors, Serotonin; Reference Values; Serotonin Antagonists; Single-Blind Method	1993
The control of acute cisplatin-induced emesis--a comparative study of granisetron and a combination regimen of high-dose metoclopramide and dexamethasone. Granisetron Study Group. British journal of cancer, 1993, Volume: 68, Issue:1 Topics: Blood Pressure; Cisplatin; Dexamethasone; Drug Therapy, Combination; Female; Granisetron; Humans; Indazoles; Male; Metoclopramide; Middle Aged; Nausea; Neoplasms; Pulse	1993
The antiemetic efficacy and safety of granisetron compared with metoclopramide plus dexamethasone in patients receiving fractionated chemotherapy over 5 days. The Granisetron Study Group. Journal of cancer research and clinical oncology, 1993, Volume: 119, Issue:9 Topics: Antiemetics; Antineoplastic Agents; Cisplatin; Dexamethasone; Drug Administration Schedule; Drug Therapy, Combination; Etoposide; Female; Granisetron; Humans; Ifosfamide; Indazoles; Male; Metoclopramide; Middle Aged; Vomiting	1993
[Clinical evaluation of granisetron for nausea and vomiting induced by anticancer drugs--optimal dose-finding study]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:9 Topics: Administration, Oral; Adult; Aged; Antiemetics; Cisplatin; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Neoplasms; Vomiting	1993
[Clinical evaluation of granisetron for nausea and vomiting induced by anticancer drugs--multi-centered placebo-controlled double-blind comparative study]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:9 Topics: Administration, Oral; Antiemetics; Cisplatin; Double-Blind Method; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Tablets; Vomiting	1993
[Study on the inhibitory effect of oral granisetron against nausea/vomiting induced by cytosine arabinoside containing chemotherapy for tumors in the hematopoietic organs]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:10 Topics: Administration, Oral; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Granisetron; Humans; Indazoles; Lymphoma; Male; Middle Aged; Mitoxantrone; Nausea; Vomiting	1993
[Granisetron oral phase III clinical trial--study on the inhibitory effect of granisetron for nausea/vomiting induced by chemotherapy for tumors in the hematopoietic organs]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:12 Topics: Administration, Oral; Adolescent; Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Drug Administration Schedule; Female; Granisetron; Hodgkin Disease; Humans; Indazoles; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged; Nausea; Vomiting	1993

Other Studies

76 other study(ies) available for indazoles and granisetron

Article	Year
Development of high-affinity 5-HT3 receptor antagonists. 1. Initial structure-activity relationship of novel benzamides. Journal of medicinal chemistry, 1992, Mar-06, Volume: 35, Issue:5 Topics: Animals; Antiemetics; Benzamides; Benzofurans; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Cisplatin; Ferrets; Granisetron; Imidazoles; Indazoles; Indoles; Male; Metoclopramide; Molecular Structure; Ondansetron; Rats; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Vomiting	1992
[Nausea and vomiting in chemotherapy]. Revue de l'infirmiere, 1992, Volume: 42, Issue:4 Topics: Antineoplastic Agents; Clinical Protocols; Granisetron; Humans; Indazoles; Nausea; Vomiting	1992
Membrane-bound and solubilized brain 5HT3 receptors: improved radioligand binding assays using bovine area postrema or rat cortex and the radioligands 3H-GR65630, 3H-BRL43694, and 3H-LY278584. Synapse (New York, N.Y.), 1992, Volume: 11, Issue:1 Topics: Animals; Binding, Competitive; Brain Chemistry; Cattle; Cerebral Cortex; Chromatography, Gel; Granisetron; Imidazoles; Indazoles; Indoles; Membranes; Radioligand Assay; Rats; Receptors, Serotonin; Tropanes	1992
Dose granisetron remain effective over multiple cycles? The Granisetron Study Group. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A Suppl 1 Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Drug Administration Schedule; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Serotonin Antagonists; Sex Factors; Vomiting	1992
Are all 5-HT3 receptor antagonists the same? European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A Suppl 1 Topics: Animals; Antiemetics; Cisplatin; Dose-Response Relationship, Drug; Ferrets; Granisetron; Imidazoles; Indazoles; Ondansetron; Serotonin Antagonists; Vomiting; Whole-Body Irradiation	1992
Effects produced by acute and chronic treatment with granisetron alone or in combination with haloperidol on midbrain dopamine neurons. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1992, Volume: 2, Issue:2 Topics: Animals; Clozapine; Dopamine; Granisetron; Haloperidol; Indazoles; Male; Microelectrodes; Neurons; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Substantia Nigra; Tegmentum Mesencephali	1992
Morphine 6-glucuronide: a metabolite of morphine with greater emetic potency than morphine in the ferret. British journal of pharmacology, 1992, Volume: 106, Issue:1 Topics: Animals; Cyclophosphamide; Dose-Response Relationship, Drug; Emetics; Ferrets; Granisetron; Imidazoles; Indazoles; Injections, Subcutaneous; Morphine; Morphine Derivatives; Naloxone; Ondansetron; Vomiting	1992
[High affinity binding of Y-25130 for serotonin 3 receptor]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1992, Volume: 100, Issue:2 Topics: Animals; Antiemetics; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Granisetron; In Vitro Techniques; Indazoles; Male; Ondansetron; Oxazines; Rats; Rats, Wistar; Receptors, Serotonin; Synaptic Membranes	1992
The budgetary impact of 5-HT3 receptor antagonists in the management of chemotherapy-induced emesis. European journal of cancer (Oxford, England : 1990), 1992, Volume: 29A, Issue:1 Topics: Antiemetics; Antineoplastic Agents; Drug Costs; Granisetron; Humans; Indazoles; Models, Theoretical; Nausea; Ondansetron; Serotonin Antagonists; Vomiting	1992
Caring for the cancer patient: managing emesis now. An interactive workshop. Proceedings of a satellite symposium to the 6th European Conference on Clinical Oncology. Florence, October 1991. European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A Suppl 1 Topics: Antiemetics; Antineoplastic Agents; Granisetron; Humans; Indazoles; Nausea; Vomiting	1992
Actions of serotonin antagonists on cholera-toxin-induced intestinal fluid secretion. Acta physiologica Scandinavica, 1992, Volume: 145, Issue:3 Topics: Animals; Body Fluids; Cholera Toxin; Female; Granisetron; Imidazoles; Indazoles; Intestinal Mucosa; Ketanserin; Lysergic Acid Diethylamide; Male; Methysergide; Ondansetron; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Zimeldine	1992
Profiles of interaction of R(+)/S(-)-zacopride and anxiolytic agents in a mouse model. European journal of pharmacology, 1992, Jul-21, Volume: 218, Issue:1 Topics: Animals; Anti-Anxiety Agents; Antiemetics; Behavior, Animal; Benzamides; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlordiazepoxide; Fenclonine; Granisetron; Indazoles; Male; Mice; Neurotransmitter Agents; Ondansetron; Receptors, Cholecystokinin; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Stereoisomerism	1992
Who should receive a 5-HT3 antagonist? Lancet (London, England), 1992, Oct-31, Volume: 340, Issue:8827 Topics: Acute Disease; Antineoplastic Agents; Granisetron; Humans; Indazoles; Nausea; Ondansetron; Serotonin Antagonists; Vomiting	1992
An ethological study of the effects of buspirone and the 5-HT3 receptor antagonist, BRL 43694 (granisetron) on behaviour during social interactions in female and male mice. Neuropharmacology, 1991, Volume: 30, Issue:4 Topics: Animals; Buspirone; Female; Granisetron; Indazoles; Male; Mice; Mice, Inbred DBA; Serotonin Antagonists; Sex Factors; Social Behavior	1991
Granisetron, a selective 5-HT3 receptor antagonist, for the prevention of radiation induced emesis during total body irradiation. Bone marrow transplantation, 1991, Volume: 7, Issue:6 Topics: Adolescent; Adult; Bone Marrow Transplantation; Female; Granisetron; Humans; Indazoles; Injections, Intravenous; Male; Middle Aged; Serotonin Antagonists; Vomiting; Whole-Body Irradiation	1991
5-HT3 receptor blockers. Surgery, 1991, Volume: 110, Issue:3 Topics: Granisetron; Humans; Imidazoles; Indazoles; Ondansetron; Receptors, Serotonin; Vagus Nerve	1991
[Persistence of the control of the fluctuations of heart rate in the anesthetized and pithed adult rat. Effect of enteraminergic drugs]. Bollettino della Societa italiana di biologia sperimentale, 1991, Volume: 67, Issue:1 Topics: Anesthesia; Animals; Decerebrate State; Depression, Chemical; Dose-Response Relationship, Drug; Ether; Female; Granisetron; Heart Rate; Indazoles; Male; Piperidines; Rats; Ritanserin; Serotonin Antagonists	1991
Pharmacologic profile of (R)-5-[(1-methyl-3-indolyl)carbonyl]-4,5,6,7-tetrahydro-1H- benzimidazole hydrochloride (YM060), a potent and selective 5-hydroxytryptamine3 receptor antagonist, and its enantiomer in the isolated tissue. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:1 Topics: Animals; Benzimidazoles; Dogs; Female; Granisetron; Guinea Pigs; Imidazoles; Indazoles; Male; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardial Contraction; Ondansetron; Receptors, Adrenergic; Receptors, Histamine; Serotonin Antagonists; Stereoisomerism	1991
Efficacy and safety of granisetron in the prevention of chemotherapy-induced emesis in paediatric patients. European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:9 Topics: Adolescent; Antineoplastic Agents; Child; Child, Preschool; Female; Granisetron; Humans; Indazoles; Male; Nausea; Prognosis; Serotonin Antagonists; Time Factors; Vomiting	1991
Preliminary evidence for the involvement of the putative 5-HT4 receptor in zacopride- and copper sulphate-induced vomiting in the ferret. European journal of pharmacology, 1991, Nov-12, Volume: 204, Issue:3 Topics: Analysis of Variance; Animals; Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Copper; Copper Sulfate; Female; Ferrets; Granisetron; Imidazoles; Indazoles; Indoles; Loperamide; Male; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Tropisetron; Vomiting	1991
Evidence that the amygdala is involved in the disinhibitory effects of 5-HT3 receptor antagonists. Psychopharmacology, 1991, Volume: 104, Issue:4 Topics: Amygdala; Animals; Anxiety; Conflict, Psychological; Granisetron; Imidazoles; Indazoles; Indoles; Lighting; Male; Ondansetron; Raphe Nuclei; Rats; Serotonin; Serotonin Antagonists; Social Behavior; Tropanes; Tropisetron	1991
Memory enhancing effects of granisetron (BRL 43694) in a passive avoidance task. European journal of pharmacology, 1991, Oct-02, Volume: 203, Issue:1 Topics: Animals; Avoidance Learning; Electroshock; Granisetron; Indazoles; Male; Memory; Mice; Serotonin Antagonists	1991
The 5-HT3 receptor antagonists LY 277359 and granisetron potentiate the suppressant action of apomorphine on the basal firing rate of ventral tegmental dopamine cells. European journal of pharmacology, 1991, Dec-17, Volume: 209, Issue:3 Topics: Animals; Apomorphine; Benzofurans; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dopamine; Drug Synergism; Granisetron; Indazoles; Male; Microelectrodes; Neurons; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stereotaxic Techniques; Substantia Nigra; Tegmentum Mesencephali	1991
Cisplatin-evoked induction of c-fos protein in the brainstem of the ferret: the effect of cervical vagotomy and the anti-emetic 5-HT3 receptor antagonist granisetron (BRL 43694). Brain research, 1991, Nov-29, Volume: 565, Issue:2 Topics: Animals; Antiemetics; Brain Stem; Cisplatin; Female; Ferrets; Granisetron; Immunohistochemistry; Indazoles; Male; Neck; Nerve Tissue Proteins; Neurons; Proto-Oncogene Proteins c-fos; Serotonin Antagonists; Vagotomy; Vagus Nerve	1991
The effect of a 5-HT3-antagonist on the ileal brake mechanism in the rat. The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:7 Topics: Animals; Fat Emulsions, Intravenous; Gastrointestinal Transit; Granisetron; Ileum; Indazoles; Injections, Subcutaneous; Male; Rats; Receptors, Serotonin; Serotonin Antagonists	1991
5-HT3 receptor antagonists inhibit sensory neuropeptide release from the rat spinal cord. Neuroreport, 1990, Volume: 1, Issue:2 Topics: Animals; Calcitonin Gene-Related Peptide; Granisetron; In Vitro Techniques; Indazoles; Indoles; Neurokinin A; Neurons, Afferent; Neuropeptides; Potassium; Rats; Rats, Inbred Strains; Serotonin Antagonists; Spinal Cord; Substance P; Tropisetron	1990
Endogenous 5-hydroxytryptamine modulates the release of tachykinins and calcitonin gene-related peptide from the rat spinal cord via 5-HT3 receptors. Annals of the New York Academy of Sciences, 1991, Volume: 632 Topics: Animals; Calcitonin Gene-Related Peptide; Granisetron; In Vitro Techniques; Indazoles; Indoles; Neurokinin A; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Substance P; Tachykinins; Tropisetron	1991
Neuroendocrine responses to L-tryptophan as an index of brain serotonin function: effect of weight loss. Advances in experimental medicine and biology, 1991, Volume: 294 Topics: Adult; Biological Transport, Active; Brain Chemistry; Clomipramine; Depression; Diet, Reducing; Female; Granisetron; Growth Hormone; Humans; Hydroxyindoleacetic Acid; Indazoles; Infusions, Intravenous; Male; Metergoline; Metoclopramide; Neurosecretory Systems; Prolactin; Ritanserin; Serotonin; Sex Characteristics; Synaptic Transmission; Thyrotropin-Releasing Hormone; Tryptophan; Tryptophan Hydroxylase; Weight Loss	1991
Effects of 5-hydroxytryptamine 3 receptor antagonists on gastrointestinal motor activity in conscious dogs. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 256, Issue:1 Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Digestion; Dogs; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Granisetron; Imidazoles; Indazoles; Indoles; Infusions, Intravenous; Injections, Intravenous; Male; Motilin; Motor Activity; Muscle Contraction; Muscle, Smooth; Ondansetron; Serotonin Antagonists; Time Factors; Tropisetron	1991
Involvement of 5-hydroxytryptamine 3 receptors in regulation of interdigestive gastric contractions by motilin in the dog. Gastroenterology, 1991, Volume: 100, Issue:4 Topics: Acetylcholine; Animals; Digestion; Dogs; Gastrointestinal Motility; Granisetron; Imidazoles; Indazoles; Motilin; Muscle Contraction; Muscle, Smooth; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Stomach	1991
Serotonin antagonists: a new class of antiemetic agents. Journal of the National Cancer Institute, 1991, May-01, Volume: 83, Issue:9 Topics: Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Granisetron; Humans; Imidazoles; Indazoles; Indoles; Metoclopramide; Ondansetron; Quinolizines; Receptors, Serotonin; Serotonin Antagonists; Tropanes; Tropisetron; Vomiting	1991
Ketotifen and its analogues reduce aversive responding in the rodent. Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:4 Topics: Animals; Avoidance Learning; Behavior, Animal; Benzamides; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cocaine; Diazepam; Ethanol; Exploratory Behavior; Granisetron; Indazoles; Ketotifen; Male; Mice; Mice, Inbred Strains; Nicotine; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin Antagonists; Social Behavior	1990
[Study on mechanism of interdigestive migrating contractions of a canine stomach]. Nihon Heikatsukin Gakkai zasshi, 1990, Volume: 26, Issue:5 Topics: Animals; Dogs; Fasting; Gastrointestinal Motility; Granisetron; Indazoles; Motilin; Muscle Contraction; Muscle, Smooth; Serotonin Antagonists; Stomach	1990
5-HT3 receptor antagonists attenuate dopamine-induced hyperactivity in the rat. Neuroreport, 1990, Volume: 1, Issue:1 Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dopamine; Dopamine Antagonists; Female; Granisetron; Indazoles; Indoles; Injections; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tropisetron	1990
Phase I/II trial of granisetron: a novel 5-hydroxytryptamine antagonist for the prevention of chemotherapy-induced nausea and vomiting. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:2 Topics: Antiemetics; Antineoplastic Agents; Aspartate Aminotransferases; Chromatography, High Pressure Liquid; Cisplatin; Doxorubicin; Drug Evaluation; Drug Tolerance; Granisetron; Humans; Indazoles; Nausea; Pyrazoles; Serotonin Antagonists; Vomiting	1990
The 5-HT3 antagonist, BRL 43694, does not compromise the efficacy of cisplatin in tumour-bearing mice. Cancer chemotherapy and pharmacology, 1990, Volume: 25, Issue:5 Topics: Animals; Cisplatin; Drug Interactions; Drug Therapy, Combination; Granisetron; Indazoles; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma; Pyrazoles; Serotonin Antagonists	1990
Chronic BRL 43694, a selective 5-HT3 receptor antagonist, fails to alter the number of spontaneously active midbrain dopamine neurons. European journal of pharmacology, 1990, Jan-17, Volume: 175, Issue:3 Topics: Animals; Cells, Cultured; Dopamine; Granisetron; Indazoles; Male; Mesencephalon; Microelectrodes; Neurons; Pyrazoles; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin Antagonists	1990
Chronic administration of the 5-HT3 receptor antagonist BRL 43694; effects on reflex epilepsy and social behaviour of the Mongolian gerbil. Psychopharmacology, 1990, Volume: 101, Issue:2 Topics: Aggression; Animals; Drinking; Epilepsy; Gerbillinae; Granisetron; Grooming; Indazoles; Male; Pyrazoles; Serotonin Antagonists; Social Behavior	1990
Emesis and defecations induced by the 5-hydroxytryptamine (5-HT3) receptor antagonist zacopride in the ferret. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 253, Issue:3 Topics: Administration, Oral; Animals; Antiemetics; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Defecation; Dose-Response Relationship, Drug; Ferrets; Granisetron; Indazoles; Injections, Intravenous; Male; Metoclopramide; Pyrazoles; Serotonin; Serotonin Antagonists; Vagotomy; Vomiting	1990
RG 12915: a potent 5-hydroxytryptamine-3 antagonist that is an orally effective inhibitor of cytotoxic drug-induced emesis in the ferret and dog. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2 Topics: Administration, Oral; Animals; Antiemetics; Antineoplastic Agents; Benzofurans; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cisplatin; Dogs; Dopamine; Ferrets; Gastric Emptying; Granisetron; Imidazoles; Indazoles; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Vomiting	1990
Behavioural effects in gerbils of the 5-HT3 receptor antagonists, BRL 43694 and ICS 205-930, under circumstances of high and low light intensity. Neuropharmacology, 1990, Volume: 29, Issue:6 Topics: Animals; Behavior, Animal; Gerbillinae; Granisetron; Indazoles; Indoles; Light; Male; Pyrazoles; Serotonin Antagonists; Social Behavior; Tropisetron	1990
The effects of granisetron, ICS 205-930 and ondansetron on the visceral pain reflex induced by duodenal distension. British journal of pharmacology, 1990, Volume: 100, Issue:3 Topics: Animals; Blood Pressure; Duodenum; Granisetron; Imidazoles; Indazoles; Indoles; Male; Morphine; Muscle Contraction; Muscle, Smooth; Ondansetron; Pain; Pyrazoles; Rats; Rats, Inbred Strains; Reflex; Serotonin Antagonists; Stomach; Tropisetron; Vagotomy	1990
Analysis of the actions of 5-hydroxytryptamine on the rabbit isolated vagus nerve. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:6 Topics: Action Potentials; Animals; Biguanides; Citalopram; Electric Stimulation; Evoked Potentials; Female; gamma-Aminobutyric Acid; Granisetron; Indazoles; Male; Membrane Potentials; Metoclopramide; Motor Neurons; Rabbits; Serotonin; Vagus Nerve	1990
Antagonism of the effects of 5-hydroxytryptamine on the rabbit isolated vagus nerve by BRL 43694 and metoclopramide. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:6 Topics: Action Potentials; Animals; Dimethylphenylpiperazinium Iodide; Female; gamma-Aminobutyric Acid; Granisetron; In Vitro Techniques; Indazoles; Kinetics; Male; Metoclopramide; Pyrazoles; Rabbits; Serotonin; Serotonin Antagonists; Vagus Nerve	1990
The symptomatic control of cytostatic drug-induced emesis. A recent history and review. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26 Suppl 1 Topics: Antiemetics; Antineoplastic Agents; Granisetron; Humans; Indazoles; Serotonin Antagonists; Vomiting	1990
An overview on the use of granisetron in the treatment of emesis associated with cytostatic chemotherapy. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26 Suppl 1 Topics: Antineoplastic Agents; Constipation; Granisetron; Headache; Humans; Indazoles; Serotonin Antagonists; Time Factors; Vomiting	1990
The role of specific 5-HT3 receptor antagonism in the control of cytostatic drug-induced emesis. European journal of cancer (Oxford, England : 1990), 1990, Volume: 26 Suppl 1 Topics: Animals; Antineoplastic Agents; Brain; Dose-Response Relationship, Drug; Ferrets; Granisetron; Heart Rate; Indazoles; Male; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Vomiting	1990
Evidence for presynaptic 5-hydroxytryptamine3 recognition sites on vagal afferent terminals in the brainstem of the ferret. Neuroscience, 1990, Volume: 38, Issue:3 Topics: Afferent Pathways; Animals; Binding Sites; Brain Stem; Denervation; Ferrets; Granisetron; Indazoles; Nerve Endings; Nodose Ganglion; Receptors, Serotonin; Serotonin Antagonists; Splanchnic Nerves; Synapses; Vagus Nerve	1990
The conduct of clinical trials in the area of emesis control. Seminars in oncology nursing, 1990, Volume: 6, Issue:4 Suppl 1 Topics: Antiemetics; Clinical Trials as Topic; Drug Evaluation; Granisetron; Humans; Indazoles; Oncology Nursing; Vomiting	1990
Evidence for the presynaptic action of 5-hydroxytryptamine and the involvement of purinergic innervation in the rabbit lower urinary tract. British journal of pharmacology, 1990, Volume: 101, Issue:1 Topics: Adenosine Triphosphate; Animals; Atropine; Electric Stimulation; Female; Granisetron; In Vitro Techniques; Indazoles; Indoles; Male; Muscle Contraction; Muscle, Smooth; Purines; Rabbits; Serotonin; Serotonin Antagonists; Synapses; Tropanes; Tropisetron; Urethra; Urinary Tract	1990
Selective and functional 5-hydroxytryptamine3 receptor antagonism by BRL 43694 (granisetron). European journal of pharmacology, 1989, Jan-10, Volume: 159, Issue:2 Topics: Acetylcysteine; Anesthesia; Animals; Brain Chemistry; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Granisetron; Guinea Pigs; Heart; In Vitro Techniques; Indazoles; Membranes; Muscle, Smooth; Pyrazoles; Rabbits; Rats; Receptors, Serotonin; Serotonin Antagonists; Sincalide	1989
A pharmacokinetic study of granisetron (BRL 43694A), a selective 5-HT3 receptor antagonist: correlation with anti-emetic response. Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:1 Topics: Adult; Aged; Antiemetics; Basal Metabolism; Chromatography, High Pressure Liquid; Cisplatin; Female; Granisetron; Half-Life; Humans; Indazoles; Male; Middle Aged; Nausea; Pyrazoles; Serotonin Antagonists	1989
[3H]-BRL 43694 (Granisetron), a specific ligand for 5-HT3 binding sites in rat brain cortical membranes. Biochemical pharmacology, 1989, May-15, Volume: 38, Issue:10 Topics: Animals; Cerebral Cortex; Granisetron; In Vitro Techniques; Indazoles; Male; Pyrazoles; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin Antagonists	1989
A phase I study of a new 5HT3-receptor antagonist, BRL43694A, an agent for the prevention of chemotherapy-induced nausea and vomiting. Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:3 Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Drug Evaluation; Drug Tolerance; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Neoplasms; Pyrazoles; Serotonin Antagonists; Vomiting	1989
BRL 43694, a new 5HT3 receptor antagonist, prevents cisplatin-induced emesis in dogs. Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11, Issue:5 Topics: Animals; Cisplatin; Dogs; Female; Granisetron; Indazoles; Male; Pyrazoles; Serotonin Antagonists; Vomiting	1989
[BRL 43694A--a 5-hydroxytryptamine receptor blocker as an antiemetic in cytostatic therapy]. Schweizerische medizinische Wochenschrift, 1989, Jun-10, Volume: 119, Issue:23 Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Drug Evaluation; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Pyrazoles; Serotonin Antagonists; Vomiting	1989
Lack of effects of 5HT3 receptor antagonists in the social interaction and elevated plus-maze tests of anxiety in the rat. Psychopharmacology, 1989, Volume: 99, Issue:2 Topics: Animals; Anxiety; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chlordiazepoxide; Granisetron; Imidazoles; Indazoles; Male; Motor Activity; Ondansetron; Rats; Serotonin Antagonists; Social Behavior	1989
The 5-HT3 receptor ligand, [3H]BRL 43694, binds to presynaptic sites in the nucleus tractus solitarius of the rat. Neuropharmacology, 1989, Volume: 28, Issue:12 Topics: Animals; Autoradiography; Ganglionectomy; Granisetron; In Vitro Techniques; Indazoles; Male; Medulla Oblongata; Nodose Ganglion; Pyrazoles; Radioligand Assay; Rats; Rats, Inbred Strains; Serotonin Antagonists	1989
BRL 43694. Cancer investigation, 1989, Volume: 7, Issue:5 Topics: Antineoplastic Agents; Granisetron; Humans; Indazoles; Pyrazoles; Serotonin Antagonists; Vomiting	1989
Characterization of 5-hydroxytryptamine3 receptors in the medial prefrontal cortex: a microiontophoretic study. European journal of pharmacology, 1989, Dec-07, Volume: 173, Issue:2-3 Topics: Animals; Cerebral Cortex; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Granisetron; Indazoles; Indoles; Iontophoresis; Magnesium Chloride; Male; Metergoline; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tropisetron	1989
[Effect of 5-HT3 receptor antagonists on gastrointestinal motility]. Nihon Heikatsukin Gakkai zasshi, 1989, Volume: 25, Issue:6 Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dogs; Gastrointestinal Motility; Granisetron; Imidazoles; In Vitro Techniques; Indazoles; Indoles; Motilin; Ondansetron; Rabbits; Serotonin Antagonists; Tropisetron	1989
The serotonin type 3 receptor antagonist BRL 43694 and nausea and vomiting induced by cisplatin. BMJ (Clinical research ed.), 1988, Jul-09, Volume: 297, Issue:6641 Topics: Cisplatin; Dose-Response Relationship, Drug; Female; Granisetron; Humans; Indazoles; Male; Nausea; Pyrazoles; Serotonin Antagonists	1988
BRL 43694: a novel antiemetic to prevent nausea and vomiting induced by chemotherapy. Journal of the National Cancer Institute, 1988, Oct-19, Volume: 80, Issue:16 Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Female; Granisetron; Humans; Indazoles; Male; Middle Aged; Nausea; Pyrazoles; Vomiting	1988
The anti-emetic potential of the 5-hydroxytryptamine3 receptor antagonist BRL 43694. British journal of cancer, 1988, Volume: 58, Issue:5 Topics: Animals; Apomorphine; Cisplatin; Cyclophosphamide; Dogs; Doxorubicin; Ferrets; Granisetron; Indazoles; Male; Pyrazoles; Triazines; Vomiting; Whole-Body Irradiation	1988
Pharmacokinetics and anti-emetic efficacy of BRL43694, a new selective 5HT-3 antagonist. British journal of cancer, 1988, Volume: 58, Issue:5 Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Drug Tolerance; Female; Granisetron; Half-Life; Humans; Indazoles; Male; Middle Aged; Pilot Projects; Pyrazoles; Vomiting	1988
Identification of 5-HT3 recognition sites in the ferret area postrema. The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:8 Topics: Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carnivora; Cerebral Ventricles; Female; Ferrets; Granisetron; In Vitro Techniques; Indazoles; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists	1988
Serotonin-induced vasodilatation in the human forearm is mediated by the "nitric oxide-pathway": no evidence for involvement of the 5-HT3-receptor. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:1 Topics: Adult; Amino Acid Oxidoreductases; Arginine; Forearm; Free Radical Scavengers; Granisetron; Guanylate Cyclase; Humans; Indazoles; Male; Methylene Blue; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Ondansetron; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Vasodilation	1993
Granisetron and ondansetron: effects on the ileal brake mechanism in the rat. The Journal of pharmacy and pharmacology, 1993, Volume: 45, Issue:6 Topics: Animals; Dose-Response Relationship, Drug; Gastrointestinal Transit; Granisetron; Ileum; Indazoles; Lipids; Male; Ondansetron; Rats; Sensitivity and Specificity; Serotonin Antagonists	1993
Clinical studies with granisetron, a new 5-HT3 receptor antagonist for the treatment of cancer chemotherapy-induced emesis. The Granisetron Study Group. European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A Suppl 1 Topics: Adult; Aged; Antiemetics; Antineoplastic Agents; Constipation; Dose-Response Relationship, Drug; Female; Granisetron; Headache; Humans; Indazoles; Male; Middle Aged; Serotonin Antagonists; Vomiting	1993
5-HT3 receptor antagonists inhibit morphine-induced stimulation of mesolimbic dopamine release and function in the rat. European journal of pharmacology, 1993, Jan-05, Volume: 230, Issue:1 Topics: Animals; Behavior, Animal; Dialysis; Dopamine; Dose-Response Relationship, Drug; Granisetron; Indazoles; Indoles; Limbic System; Male; Morphine; Ondansetron; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tropisetron	1993
Litoxetine: a selective 5-HT uptake inhibitor with concomitant 5-HT3 receptor antagonist and antiemetic properties. European journal of pharmacology, 1993, Mar-02, Volume: 232, Issue:2-3 Topics: Animals; Antiemetics; Binding, Competitive; Cerebral Cortex; Cisplatin; Dose-Response Relationship, Drug; Ferrets; Fluoxetine; Granisetron; Indazoles; Male; Piperidines; Quipazine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Vomiting	1993
Reduction of rectal sensitivity and post-prandial motility by granisetron, a 5 HT3-receptor antagonist, in patients with irritable bowel syndrome. Alimentary pharmacology & therapeutics, 1993, Volume: 7, Issue:2 Topics: Adult; Colonic Diseases, Functional; Eating; Female; Granisetron; Humans; Indazoles; Male; Rectum; Serotonin Antagonists	1993
Repeated use of granisetron in patients receiving cytostatic agents. Cancer, 1993, Jun-15, Volume: 71, Issue:12 Topics: Adult; Age Factors; Aged; Antiemetics; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Constipation; Female; Granisetron; Headache; Humans; Indazoles; Infusions, Intravenous; Male; Middle Aged; Nausea; Remission Induction; Serotonin Antagonists; Vomiting	1993
[The prevention of CDDP-induced emesis with granisetron]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:8 Topics: Antiemetics; Cisplatin; Female; Granisetron; Humans; Indazoles; Infusions, Intravenous; Nausea; Ovarian Neoplasms; Uterine Neoplasms; Vomiting	1993
Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron. Biochemical pharmacology, 1993, May-25, Volume: 45, Issue:10 Topics: Animals; Benzamides; Biguanides; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cell Membrane; Glioma; Granisetron; Indazoles; Kinetics; Neuroblastoma; Ondansetron; Quipazine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium	1993
[Antiemetic efficacy of granisetron in patients receiving 5-day continuous infusion of cisplatin]. Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:12 Topics: Adenocarcinoma; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cisplatin; Drug Administration Schedule; Etoposide; Female; Granisetron; Humans; Indazoles; Infusions, Intra-Arterial; Lung Neoplasms; Male; Middle Aged; Nausea; Vindesine; Vomiting	1993