Page last updated: 2024-08-21

indazoles and fulvestrant

indazoles has been researched along with fulvestrant in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Bates, D; Bean, JR; Demidenko, E; Dillon, LM; Eastman, AR; Hosford, SR; Lewis, LD; Liu, SC; Marotti, JD; Miller, TW; Nannini, MA; Pang, J; Salphati, L; Shee, K; Yang, W; Zhang, X1
Aimi, J; Amler, LC; Chan, IT; Chen, M; Derynck, MK; Gendreau, S; Hampton, GM; Johnston, S; Krop, I; Lackner, MR; Qiu, J; Savage, H; Schmid, P; Spoerke, JM; Walter, K; Wilson, TR1
Blake, RA; Chalouni, C; Chen, IP; Daemen, A; De Bruyn, T; Friedman, LS; Giltnane, JM; Guan, J; Hafner, M; Hager, JH; Hartman, SJ; Heidersbach, A; Houtman, R; Ingalla, E; Kategaya, L; Kleinheinz, T; Li, J; Martin, SE; Metcalfe, C; Modrusan, Z; Nannini, M; Oeh, J; Sampath, D; Ubhayakar, S; Wang, X; Wertz, IE; Young, A; Yu, M; Zhou, W1
Ala-Hongisto, H; Bertula, K; Elo, LL; Euro, L; Heikkilä, P; Hollmann, B; Hukkinen, K; Ikkala, O; Joensuu, H; Junttila, MR; Kivento, M; Klefström, J; Kovanen, P; Leidenius, M; Martikainen, L; Mattson, J; Meretoja, T; Metcalfe, C; Monni, O; Munne, PM; Mutka, M; Nevalaita, L; Patrikainen, L; Peura, A; Pokki, J; Pouwels, J; Räty, I; Ruuska, J; Sahu, B; Salmela, M; Suomi, T; Väänänen, J; Yavuz, K1
Aithal, KB; Albacker, LA; Banka, D; Bolduc, DM; Furman, C; Hao, MH; Irwin, S; Kim, A; Korpal, M; Larsen, N; Montesion, M; Moriarty, AD; Murugesan, K; Nguyen, TV; Prajapati, S; Puyang, X; Rimkunas, V; Sahmoud, T; Vaillancourt, FH; Wick, MJ; Wu, ZJ; Yao, S; Zeng, H; Zhang, X; Zhang, Z; Zheng, GZ; Zhu, P1

Trials

2 trial(s) available for indazoles and fulvestrant

ArticleYear
Pictilisib stalls advanced ER+/PR+ breast cancer.
    Cancer discovery, 2015, Volume: 5, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Estradiol; Female; Fulvestrant; Humans; Indazoles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Receptors, Estrogen; Receptors, Progesterone; Sulfonamides

2015
Heterogeneity and clinical significance of ESR1 mutations in ER-positive metastatic breast cancer patients receiving fulvestrant.
    Nature communications, 2016, 05-13, Volume: 7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Class I Phosphatidylinositol 3-Kinases; Disease-Free Survival; DNA Mutational Analysis; DNA, Neoplasm; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Estrogens; Female; Fulvestrant; Humans; Indazoles; Middle Aged; Mutation; Protein Kinase Inhibitors; Sulfonamides

2016

Other Studies

4 other study(ies) available for indazoles and fulvestrant

ArticleYear
Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha-Positive, PIK3CA-Mutant Breast Cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, 05-01, Volume: 22, Issue:9

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Drug Resistance, Neoplasm; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Fulvestrant; Humans; Indazoles; MCF-7 Cells; Mice; Mice, Inbred NOD; Mutation; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides; Therapeutic Index

2016
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its Mobility.
    Cell, 2019, 08-08, Volume: 178, Issue:4

    Topics: Animals; Breast Neoplasms; Cell Proliferation; Cinnamates; Drug Resistance, Neoplasm; Estrogen Receptor Antagonists; Female; Fulvestrant; HEK293 Cells; Heterografts; Humans; Indazoles; Ligands; MCF-7 Cells; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Polymorphism, Single Nucleotide; Proteolysis; Receptors, Estrogen; Signal Transduction; Transcription, Genetic

2019
Compressive stress-mediated p38 activation required for ERα + phenotype in breast cancer.
    Nature communications, 2021, 11-29, Volume: 12, Issue:1

    Topics: Breast Neoplasms; Case-Control Studies; Cell Line, Tumor; Cinnamates; Collagen; Drug Combinations; Enhancer of Zeste Homolog 2 Protein; Estradiol; Estrogen Receptor alpha; Female; Fulvestrant; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histones; Humans; Indazoles; Laminin; Mammary Glands, Human; Mechanotransduction, Cellular; p38 Mitogen-Activated Protein Kinases; Phenotype; Proteoglycans; Tamoxifen; Tissue Culture Techniques; Transcriptome

2021
Covalent ERα Antagonist H3B-6545 Demonstrates Encouraging Preclinical Activity in Therapy-Resistant Breast Cancer.
    Molecular cancer therapeutics, 2022, 06-01, Volume: 21, Issue:6

    Topics: Breast Neoplasms; Clinical Trials as Topic; Estrogen Receptor alpha; Female; Fulvestrant; Humans; Indazoles; Neoplasm Recurrence, Local; Pyridines

2022