Page last updated: 2024-08-21

indazoles and dinoprostone

indazoles has been researched along with dinoprostone in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's5 (41.67)29.6817
2010's6 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruneau, P; Delvare, C; Edwards, MP; McMillan, RM1
Alcaraz, MJ; Aller, E; Fernández, P; Guillén, MI; López-Cremades, P; Lorenzo, A; Molina, P; Ubeda, A1
Cury, Y; Picolo, G1
Chang, MS; Chen, BC; Lee, WS; Lin, CH; Sheu, JR1
Bachteeva, V; Fock, E; Gambaryan, S; Lavrova, E; Nikolaeva, S; Parnova, R1
Fu, WM; Jeng, KC; Kuo, SC; Lee, FY; Liou, HC; Lu, DY; Tang, CH; Teng, CM1
Borda, E; Busch, L; Miozza, V; S-Borda, L1
Audoly, LP; Ito, S; Katano, T; Kunori, S; Matsumura, S; Okuda-Ashitaka, E; Urade, Y1
Chang, WD; Chang, YW; Chung, PJ; Fang, YC; Hwang, TL; Kuo, LM; Tang, MC1
Conrads, TP; Haines, DC; Hilton, MB; Kalen, J; Logsdon, D; Morris, H; Patel, NL; Seaman, S; St Croix, B; Stevens, J; Swing, DA; Veenstra, TD; Xu, L; Zudaire, E1
Frei, RB; Hammer, A; Heinemann, A; Lippe, IT; Parzmair, GP; Radnai, B; Schuligoi, R; Sturm, EM; Sturm, GJ1
Bourn, J; Cekanova, M1

Other Studies

12 other study(ies) available for indazoles and dinoprostone

ArticleYear
Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Administration, Oral; Animals; Chemical Phenomena; Chemistry; Dinoprostone; Dogs; Humans; Indazoles; Leukotriene B4; Lipoxygenase Inhibitors; Male; Methemoglobinemia; Methylation; Molecular Structure; Oxidation-Reduction; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship; Thromboxane B2

1991
A novel indazolo-triazolo-benzotriazepine exerts anti-inflammatory effects by inhibition of cyclooxygenase-2 activity and nitric oxide synthase-2 expression.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Azepines; Blood Platelets; Blotting, Western; Carrageenan; Cell Survival; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Electrophoretic Mobility Shift Assay; Female; Humans; Indazoles; Isoenzymes; Macrophages; Membrane Proteins; Mice; Microsomes; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin-Endoperoxide Synthases; Triazoles

2003
Peripheral neuronal nitric oxide synthase activity mediates the antinociceptive effect of Crotalus durissus terrificus snake venom, a delta- and kappa-opioid receptor agonist.
    Life sciences, 2004, Jun-18, Volume: 75, Issue:5

    Topics: Analgesics; Animals; Crotalid Venoms; Crotalus; Dinoprostone; Drug Antagonism; Enzyme Inhibitors; Hyperalgesia; Indazoles; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, kappa

2004
YC-1-induced cyclooxygenase-2 expression is mediated by cGMP-dependent activations of Ras, phosphoinositide-3-OH-kinase, Akt, and nuclear factor-kappaB in human pulmonary epithelial cells.
    Molecular pharmacology, 2004, Volume: 66, Issue:3

    Topics: Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclooxygenase 2; Dinoprostone; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Humans; I-kappa B Kinase; I-kappa B Proteins; Indazoles; Interleukin-1; Isoenzymes; Lung; Membrane Proteins; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphatidylinositol 3-Kinases; Polyenes; Polyunsaturated Alkamides; Proline; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; ras Proteins; Thiocarbamates; Transcription Factors

2004
Prostaglandin E2 inhibits vasotocin-induced osmotic water permeability in the frog urinary bladder by EP1-receptor-mediated activation of NO/cGMP pathway.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 293, Issue:1

    Topics: Animals; Blotting, Western; Brain Chemistry; Calcium; Cyclic AMP; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; In Vitro Techniques; Indazoles; Male; Nitric Oxide; Nitric Oxide Synthase Type I; Oxytocics; Permeability; Rana temporaria; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Signal Transduction; Urinary Bladder; Vasotocin; Water-Electrolyte Balance

2007
YC-1 attenuates LPS-induced proinflammatory responses and activation of nuclear factor-kappaB in microglia.
    British journal of pharmacology, 2007, Volume: 151, Issue:3

    Topics: Animals; Blotting, Western; Cell Line; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Activators; Gene Expression; Guanylate Cyclase; Indazoles; Lipopolysaccharides; Luciferases; Microglia; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Oxadiazoles; Proline; Quinoxalines; Rats; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiocarbamates; Thionucleotides

2007
Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis.
    Oral diseases, 2010, Volume: 16, Issue:8

    Topics: Adenine; Amylases; Animals; Calcium; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Guanidines; Indazoles; Indomethacin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Size; Ornithine; Parotid Gland; Periodontitis; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salivary Proteins and Peptides; Thiazoles

2010
A novel role of prostaglandin E2 in neuropathic pain: blockade of microglial migration in the spinal cord.
    Glia, 2011, Volume: 59, Issue:2

    Topics: Adenosine Triphosphate; Animals; Cell Movement; Cerebral Cortex; Cinnamates; Dinoprostone; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Hyperalgesia; Indazoles; Intramolecular Oxidoreductases; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Microglia; Neuralgia; Neurons; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type I; Prostaglandin-E Synthases; S-Nitrosoglutathione; Spinal Cord; Spinal Nerves

2011
YC-1 potentiates cAMP-induced CREB activation and nitric oxide production in alveolar macrophages.
    Toxicology and applied pharmacology, 2012, Apr-15, Volume: 260, Issue:2

    Topics: Animals; Colforsin; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Dinoprostone; Enzyme Activators; Guanylate Cyclase; Immunoblotting; Indazoles; Isoquinolines; Lung Diseases; Macrophages, Alveolar; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphoric Diester Hydrolases; Rats; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Sulfonamides

2012
COX-2 inhibition potentiates antiangiogenic cancer therapy and prevents metastasis in preclinical models.
    Science translational medicine, 2014, Jun-25, Volume: 6, Issue:242

    Topics: Angiogenesis Inhibitors; Animals; Axitinib; Carcinogenesis; Cell Line, Tumor; Clone Cells; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Female; Humans; Imidazoles; Indazoles; Liver Neoplasms; Mammary Neoplasms, Experimental; Mice; Neoadjuvant Therapy; Signal Transduction; Survival Analysis; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2014
Phosphoinositide-dependent protein kinase 1 (PDK1) mediates potent inhibitory effects on eosinophils.
    European journal of immunology, 2015, Volume: 45, Issue:5

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Active Transport, Cell Nucleus; Animals; Calcium Signaling; CD11b Antigen; Cell Shape; Dinoprostone; Eosinophils; Humans; Indazoles; Methyl Ethers; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Receptors, Prostaglandin E, EP4 Subtype; Respiratory Burst; Ribonucleosides; Signal Transduction

2015
Cyclooxygenase inhibitors potentiate receptor tyrosine kinase therapies in bladder cancer cells in vitro.
    Drug design, development and therapy, 2018, Volume: 12

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Axitinib; Benzamides; Caspases; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinoprostone; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Humans; Imidazoles; Indazoles; Indomethacin; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Pyridines; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Thiazoles; Urinary Bladder Neoplasms

2018