Compounds > indazoles
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indazoles and dasatinib

indazoles has been researched along with dasatinib in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (6.67)29.6817
2010's13 (86.67)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Kibble, A; Shumoogam, J; Walker, K1
Akita, K; Fujii, I; Gouda, M; Ishihama, Y; Kirii, Y; Kitagawa, D; Narumi, Y; Sugiyama, N; Yokota, K1
Robert, C; Sibaud, V1
Dalziel, G; Dean, B; Pang, J; Salphati, L; Ware, JA1
Galanis, A; Levis, M1
Berndsen, RH; Ding, X; Dyson, PJ; Griffioen, AW; Ho, CM; Nowak-Sliwinska, P; van den Bergh, H; Weiss, A1
Chehab, F; Gunthorpe, M; Holmes, JP; Lasater, EA; Massi, ES; Politi, J; Sali, A; Shah, NP; Smith, CC; Stecula, A; Tan, SK1
Amler, L; Deininger, MW; Eiring, AM; Guan, Y; Hampton, G; Lackner, M; Lu, S; O'Hare, T; Wagle, M; Wang, Y; Wongchenko, M; Yan, Y1
Broncel, M; Crosier, S; Daley, F; Finetti, MA; Holmes, K; Huang, PH; Jenks, A; Luczynski, MT; McCarthy, F; Natrajan, RC; Payne, LS; Ryall, KA; Tan, AC; Tanos, B; Todd, JR; Vyse, S; Wai, P; Williamson, D; Wong, JP1
Akula, S; Duyster, J; Kamasani, S; Kancha, RK; Manga, V; Sivan, SK; Vudem, DR1
Chen, Q; Wang, J; Wang, M; Zhong, C1
Bhamra, A; Broncel, M; Huang, PH; McCarthy, F; Paul, A; Vyse, S; Wong, JP1
Akaike, K; Hayashi, T; Hosoya, M; Kaneko, K; Kim, Y; Kobayashi, E; Kohsaka, S; Kubota, D; Mogushi, K; Mukaihara, K; Okubo, T; Saito, T; Sato, S; Suehara, Y; Tanabe, Y1
Almonacid, DE; Bascur, JP; González-Nilo, FD; Juritz, EI1
Brouwer, KLR; Ho, H; Honkakoski, P; Niskanen, J; Saran, C; Sundqvist, L1

Reviews

1 review(s) available for indazoles and dasatinib

ArticleYear
[Pigmentary disorders induced by anticancer agents. Part II: targeted therapies].
    Annales de dermatologie et de venereologie, 2013, Volume: 140, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Cetuximab; Dasatinib; ErbB Receptors; Humans; Imatinib Mesylate; Indazoles; Indoles; Ipilimumab; Niacinamide; Phenylurea Compounds; Pigmentation Disorders; Piperazines; Piperidines; Programmed Cell Death 1 Receptor; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sulfonamides; Sunitinib; Thiazoles

2013

Other Studies

14 other study(ies) available for indazoles and dasatinib

ArticleYear
American Society of Clinical Oncology--43rd annual meeting. Research into therapeutics: Part 4.
    IDrugs : the investigational drugs journal, 2007, Volume: 10, Issue:8

    Topics: Anthracyclines; Antineoplastic Agents; Biomarkers, Tumor; Biomedical Research; CA-125 Antigen; Clinical Trials as Topic; Dasatinib; Female; Humans; Indazoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Structure; Neoplasms; Ovarian Neoplasms; Pyrimidines; Snake Venoms; Sulfonamides; Thiazoles; Treatment Outcome

2007
Characterization of kinase inhibitors using different phosphorylation states of colony stimulating factor-1 receptor tyrosine kinase.
    Journal of biochemistry, 2012, Volume: 151, Issue:1

    Topics: Animals; Benzamides; Benzenesulfonates; Binding, Competitive; Cell Line; Dasatinib; Dose-Response Relationship, Drug; Humans; Imatinib Mesylate; Indazoles; Indoles; Kinetics; Niacinamide; Phenylurea Compounds; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Receptor, Macrophage Colony-Stimulating Factor; Sorafenib; Spodoptera; Staurosporine; Sulfonamides; Sunitinib; Surface Plasmon Resonance; Thiazoles; Transfection

2012
Pharmacokinetics and absorption of the anticancer agents dasatinib and GDC-0941 under various gastric conditions in dogs--reversing the effect of elevated gastric pH with betaine HCl.
    Molecular pharmaceutics, 2013, Nov-04, Volume: 10, Issue:11

    Topics: Absorption; Achlorhydria; Animals; Antineoplastic Agents; Betaine; Dasatinib; Dogs; Famotidine; Gastric Mucosa; Hydrogen-Ion Concentration; Indazoles; Male; Pentagastrin; Proton Pump Inhibitors; Pyrimidines; Stomach; Sulfonamides; Thiazoles

2013
Inhibition of c-Kit by tyrosine kinase inhibitors.
    Haematologica, 2015, Volume: 100, Issue:3

    Topics: Aminopyridines; Antineoplastic Agents; Benzothiazoles; Biomarkers; Bone Marrow; Cell Line, Tumor; Clinical Trials as Topic; Dasatinib; fms-Like Tyrosine Kinase 3; Gene Expression; Hair; Hematopoietic Stem Cells; Humans; Indazoles; Leukemia, Myeloid, Acute; Niacinamide; Phenylurea Compounds; Pigmentation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrimidines; Pyrroles; Sorafenib; Sulfonamides; Thiazoles

2015
A streamlined search technology for identification of synergistic drug combinations.
    Scientific reports, 2015, Sep-29, Volume: 5

    Topics: Antineoplastic Agents; Axitinib; Benzamides; Cell Line, Tumor; Cell Survival; Dasatinib; Dose-Response Relationship, Drug; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; Epithelial Cells; Erlotinib Hydrochloride; Humans; Imidazoles; Indazoles; Kidney; Piperazines; Pyrazoles

2015
Novel TKI-resistant BCR-ABL1 gatekeeper residue mutations retain in vitro sensitivity to axitinib.
    Leukemia, 2016, Volume: 30, Issue:6

    Topics: Axitinib; Dasatinib; Drug Screening Assays, Antitumor; Fusion Proteins, bcr-abl; Humans; Imidazoles; In Vitro Techniques; Indazoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyridazines

2016
A role for FOXO1 in BCR-ABL1-independent tyrosine kinase inhibitor resistance in chronic myeloid leukemia.
    Leukemia, 2016, Volume: 30, Issue:7

    Topics: Apoptosis; Cell Proliferation; Dasatinib; Drug Resistance, Neoplasm; Drug Tolerance; Forkhead Box Protein O1; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Indazoles; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Sulfonamides; Tumor Cells, Cultured

2016
Dual Targeting of PDGFRα and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors.
    Cell reports, 2016, 10-25, Volume: 17, Issue:5

    Topics: Apoptosis; Cell Line, Tumor; Dasatinib; Drug Resistance, Neoplasm; Gene Expression Profiling; Humans; Indazoles; Indoles; Oncogenes; Pyrimidines; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Platelet-Derived Growth Factor alpha; Rhabdoid Tumor; Sulfonamides; Sunitinib

2016
Computational analysis of ABL kinase mutations allows predicting drug sensitivity against selective kinase inhibitors.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2017, Volume: 39, Issue:5

    Topics: Axitinib; Computational Biology; Dasatinib; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Imidazoles; Indazoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Docking Simulation; Point Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl

2017
The opening/closure of the P-loop and hinge of BCR-ABL1 decodes the low/high bioactivities of dasatinib and axitinib.
    Physical chemistry chemical physics : PCCP, 2017, Aug-23, Volume: 19, Issue:33

    Topics: Axitinib; Dasatinib; Fusion Proteins, bcr-abl; Hydrogen Bonding; Imidazoles; Indazoles; Molecular Dynamics Simulation; Principal Component Analysis; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Thermodynamics

2017
Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib.
    Journal of proteomics, 2018, 01-06, Volume: 170

    Topics: Cell Line, Tumor; Dasatinib; Drug Resistance, Neoplasm; Humans; Indazoles; Neoplasm Proteins; Neoplasms; Phosphoproteins; Pyrimidines; Signal Transduction; Sulfonamides

2018
Cabozantinib and dastinib exert anti-tumor activity in alveolar soft part sarcoma.
    PloS one, 2017, Volume: 12, Issue:9

    Topics: Anilides; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dasatinib; Female; Humans; Indazoles; Mice; Mice, Inbred BALB C; Mice, Nude; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-met; Pyridines; Pyrimidines; Sarcoma, Alveolar Soft Part; src-Family Kinases; Sulfonamides; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

2017
Novel Insights for Inhibiting Mutant Heterodimer IDH1
    Molecular diagnosis & therapy, 2018, Volume: 22, Issue:3

    Topics: Amino Acid Sequence; Antineoplastic Agents; Binding Sites; Dasatinib; Dihydroergotamine; Enzyme Inhibitors; Epirubicin; Gene Expression; High-Throughput Screening Assays; Humans; Indazoles; Indoles; Isocitrate Dehydrogenase; Molecular Docking Simulation; Mutation; Phenylcarbamates; Pivampicillin; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Multimerization; Pyrimidines; Sulfonamides; Thermodynamics; Tosyl Compounds; User-Computer Interface

2018
Novel Bile Acid-Dependent Mechanisms of Hepatotoxicity Associated with Tyrosine Kinase Inhibitors.
    The Journal of pharmacology and experimental therapeutics, 2022, Volume: 380, Issue:2

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 11; Bile Acids and Salts; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cholesterol 7-alpha-Hydroxylase; Dasatinib; Hepatocytes; Humans; Indazoles; Organic Anion Transporters, Sodium-Dependent; Protein Kinase Inhibitors; Pyrimidines; Sorafenib; Sulfonamides; Symporters

2022