indazoles has been researched along with benzofurans in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Airey, JE; Campbell, HF; Darkes, P; Fitzpatrick, LR; Klein, S; Neuenschwander, K; Pendley, CE; Powers, M; Schnapper, M; Youssefyeh, RD | 1 |
| Ashby, CR; Minabe, Y; Schwartz, JE; Wang, RY | 1 |
| Airey, JE; Bostwick, JS; Decktor, DL; Fitzpatrick, LR; Gessner, GW; Lambert, RM; Martin, GE; Pendleton, RG; Pendley, CE; Youssefyeh, RD | 1 |
| Akima, M; Hamana, M; Kamei, K; Koga, T; Kuroki, T; Maruyama, N; Ohi, N; Yamaguchi, M | 1 |
| Barrett, JE; Critchett, D; Hu, W; Sokol, PT; Solomon, AJ; Toral, J; Ziai, MR | 1 |
| Arfsten, AE; Jakubowski, JA; McCowan, JR; Naughton, MA; Rose, JW; Ruterbories, KJ; Sall, DJ; Scarborough, RM; Smyth, MS; Su, T; Wyss, VL | 1 |
| Foxx-Orenstein, AE; Grider, JR; Jin, JG | 1 |
| Belvin, M; Boggs, J; Burton, B; Chan, E; Chan, J; Choo, E; Gancia, E; Heald, RA; Jackson, P; Jones, M; Merchant, M; Newman, R; Price, S; Rudewicz, P; Savy, P; Ultsch, M; Wiesmann, C; Yue, Q | 1 |
| Beall, HD; Bibby, JM; Hassani, M; Moody, CJ; Newsome, JJ; Swann, E | 1 |
| Chambers, JW; Cherry, L; Feng, Y; Figuera-Losada, M; Hernandez, P; Iqbal, S; Koenig, M; LoGrasso, PV; Park, H | 1 |
| Gao, M; Miller, KD; Wang, M; Zheng, QH | 1 |
| Boblewski, K; Kornicka, A; Lehmann, A; Marchwińska, A; Rybczyńska, A; Sączewski, F; Sączewski, J | 1 |
| Begemann, G; Draut, H; Rehm, T; Schobert, R | 1 |
| Aggarwal, R; Bartelink, I; Cripps, A; Grabowsky, J; Harb, A; Jahan, T; Leng, J; Mastroserio, I; Munster, PN; Pawlowska, N; Reinert, A; Ryan, CJ; Thomas, S; Truong, TG | 1 |
| Stone, L | 1 |
1 trial(s) available for indazoles and benzofurans
| Article | Year |
|---|---|
Inhibiting Histone Deacetylase as a Means to Reverse Resistance to Angiogenesis Inhibitors: Phase I Study of Abexinostat Plus Pazopanib in Advanced Solid Tumor Malignancies.
Topics: Acetylation; Adult; Aged; Alanine Transaminase; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Aspartate Aminotransferases; Benzofurans; Carcinoma, Renal Cell; Disease Progression; Disease-Free Survival; Drug Resistance; Drug Resistance, Neoplasm; Epigenesis, Genetic; Fatigue; Female; Gene Expression; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Indazoles; Kidney Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Pyrimidines; Sulfonamides; Thrombocytopenia; Treatment Outcome; Vascular Endothelial Growth Factor A; Young Adult | 2017 |
14 other study(ies) available for indazoles and benzofurans
| Article | Year |
|---|---|
Development of high-affinity 5-HT3 receptor antagonists. 1. Initial structure-activity relationship of novel benzamides.
Topics: Animals; Antiemetics; Benzamides; Benzofurans; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Cisplatin; Ferrets; Granisetron; Imidazoles; Indazoles; Indoles; Male; Metoclopramide; Molecular Structure; Ondansetron; Rats; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Vomiting | 1992 |
The 5-HT3 receptor antagonists LY 277359 and granisetron potentiate the suppressant action of apomorphine on the basal firing rate of ventral tegmental dopamine cells.
Topics: Animals; Apomorphine; Benzofurans; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dopamine; Drug Synergism; Granisetron; Indazoles; Male; Microelectrodes; Neurons; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stereotaxic Techniques; Substantia Nigra; Tegmentum Mesencephali | 1991 |
RG 12915: a potent 5-hydroxytryptamine-3 antagonist that is an orally effective inhibitor of cytotoxic drug-induced emesis in the ferret and dog.
Topics: Administration, Oral; Animals; Antiemetics; Antineoplastic Agents; Benzofurans; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cisplatin; Dogs; Dopamine; Ferrets; Gastric Emptying; Granisetron; Imidazoles; Indazoles; Ondansetron; Receptors, Serotonin; Serotonin Antagonists; Vomiting | 1990 |
Novel antiasthmatic agents with dual activities of thromboxane A2 synthetase inhibition and bronchodilation. VI. Indazole derivatives.
Topics: Administration, Oral; Aminophylline; Animals; Benzofurans; Bronchodilator Agents; Fatty Acids, Monounsaturated; Guinea Pigs; Histamine Antagonists; In Vitro Techniques; Indazoles; Male; Methacrylates; Pentanoic Acids; Pyridines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thromboxane-A Synthase; Trachea | 1995 |
5-HT3 receptor-independent inhibition of the depolarization-induced 86Rb efflux from human neuroblastoma cells, TE671, by ondansetron.
Topics: Anti-Anxiety Agents; Benzamides; Benzofurans; Biguanides; Bridged Bicyclo Compounds, Heterocyclic; Humans; Hypoglycemic Agents; Indazoles; Indoles; Neuroblastoma; Neurotoxins; Ondansetron; Potassium Channels; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Rubidium Radioisotopes; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Tropanes; Tropisetron; Tumor Cells, Cultured | 1995 |
Fibrinogen receptor (GPIIb-IIIa) antagonists derived from 5,6-bicyclic templates. Amidinoindoles, amidinoindazoles, and amidinobenzofurans containing the N-alpha-sulfonamide carboxylic acid function as potent platelet aggregation inhibitors.
Topics: Administration, Oral; Animals; Benzofurans; Fibrinogen; Humans; Indazoles; Indoles; Molecular Structure; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Rats; Rats, Sprague-Dawley; Receptors, Vitronectin; Sulfonamides; Vitronectin | 1997 |
Propulsion in guinea pig colon induced by 5-hydroxytryptamine (HT) via 5-HT4 and 5-HT3 receptors.
Topics: Animals; Benzofurans; Colon; Gastrointestinal Motility; Guinea Pigs; Humans; In Vitro Techniques; Indazoles; Indoles; Male; Piperidines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tropanes | 1999 |
Discovery of novel allosteric mitogen-activated protein kinase kinase (MEK) 1,2 inhibitors possessing bidentate Ser212 interactions.
Topics: Allosteric Regulation; Animals; Antineoplastic Agents; Benzofurans; Benzothiazoles; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Female; Hydrogen Bonding; Indazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Models, Molecular; Molecular Structure; Neoplasm Transplantation; Rats; Serine; Structure-Activity Relationship; Transplantation, Heterologous | 2012 |
Benzofuran-, benzothiophene-, indazole- and benzisoxazole-quinones: excellent substrates for NAD(P)H:quinone oxidoreductase 1.
Topics: Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Enzyme Assays; Humans; Indazoles; NAD(P)H Dehydrogenase (Quinone); Oxazoles; Oxidation-Reduction; Quinones; Thiophenes | 2013 |
A small molecule bidentate-binding dual inhibitor probe of the LRRK2 and JNK kinases.
Topics: Benzofurans; Binding Sites; Cell Line; Enzyme Activation; Enzyme Inhibitors; Humans; Indazoles; Inhibitory Concentration 50; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; MAP Kinase Kinase 4; Models, Molecular; Molecular Probes; Protein Binding; Protein Serine-Threonine Kinases; Small Molecule Libraries | 2013 |
Synthesis of (Z)-2-((1H-indazol-3-yl)methylene)-6-[¹¹C]methoxy-7-(piperazin-1-ylmethyl)benzofuran-3(2H)-one as a new potential PET probe for imaging of the enzyme PIM1.
Topics: Animals; Benzofurans; Carbon Isotopes; Fungal Proteins; Humans; Indazoles; Mice; Mitogen-Activated Protein Kinases; Neoplasms; Piperazines; Positron-Emission Tomography; Protein Kinase Inhibitors; Radiopharmaceuticals | 2013 |
Circulatory effect of TCS-80, a new imidazoline compound, in rats.
Topics: Animals; Benzofurans; Blood Pressure; Heart Rate; Hypotension; Idazoxan; Imidazoles; Imidazolidines; Imidazoline Receptors; Imidazolines; Indazoles; Male; Rats; Receptors, Adrenergic, alpha-2 | 2016 |
Antiangiogenic and Toxic Effects of Genistein, Usnic Acid, and Their Copper Complexes in Zebrafish Embryos at Different Developmental Stages.
Topics: Angiogenesis Inhibitors; Animals; Axitinib; Benzofurans; Cell Line, Tumor; Cell Movement; Cell Survival; Coordination Complexes; Copper; Embryo, Nonmammalian; Embryonic Development; Genistein; Humans; Imidazoles; Indazoles; Matrix Metalloproteinases; Microscopy, Fluorescence; Neovascularization, Physiologic; Zebrafish | 2017 |
Kidney cancer: Reversal of fortunes for TKI resistance.
Topics: Angiogenesis Inhibitors; Benzofurans; Histone Deacetylases; Humans; Hydroxamic Acids; Indazoles; Kidney Neoplasms; Pyrimidines; Sulfonamides | 2017 |