Compounds > indazoles
Page last updated: 2024-08-21

indazoles and alpha-synuclein

indazoles has been researched along with alpha-synuclein in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Brown, H; Henderson, MX; Lee, VMY; McGeary, I; Olufemi, MF; Sengupta, M; Trojanowski, JQ; Zhang, B1
Krainc, D; Merchant, K; Nguyen, M; Schwake, M; Severino, A; Young, TJ; Ysselstein, D1
Baekelandt, V; Cabezudo, D; Gelders, G; Lobbestael, E; Peralta Ramos, JM; Van den Haute, C; Van der Perren, A1
Aoyama, E; Dansithong, W; Dexheimer, T; Gandelman, M; Henderson, MJ; Huynh, DP; Jadhav, A; Kales, SC; Maag, G; Paul, S; Pulst, SM; Rai, G; Scoles, DR; Simeonov, A; Sun, H; Whitehill, BM; Zakharov, A1

Other Studies

4 other study(ies) available for indazoles and alpha-synuclein

ArticleYear
LRRK2 inhibition does not impart protection from α-synuclein pathology and neuron death in non-transgenic mice.
    Acta neuropathologica communications, 2019, 02-26, Volume: 7, Issue:1

    Topics: alpha-Synuclein; Animals; Cell Death; Hand Strength; Indazoles; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mice, Inbred C57BL; Neurons; Parkinson Disease; Pyrimidines

2019
LRRK2 kinase activity regulates lysosomal glucocerebrosidase in neurons derived from Parkinson's disease patients.
    Nature communications, 2019, 12-05, Volume: 10, Issue:1

    Topics: alpha-Synuclein; Cells, Cultured; Dopamine; Dopaminergic Neurons; Glucosylceramidase; Humans; Indazoles; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Lysosomes; Mutation, Missense; Parkinson Disease; Pyrimidines; RNA Interference

2019
LRRK2 Ablation Attenuates Αlpha-Synuclein-Induced Neuroinflammation Without Affecting Neurodegeneration or Neuropathology In Vivo.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2021, Volume: 18, Issue:2

    Topics: alpha-Synuclein; Animals; Indazoles; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Neurodegenerative Diseases; Neuroinflammatory Diseases; Pyrimidines; Rats; Rats, Long-Evans; Rats, Transgenic

2021
The AKT modulator A-443654 reduces α-synuclein expression and normalizes ER stress and autophagy.
    The Journal of biological chemistry, 2021, Volume: 297, Issue:4

    Topics: alpha-Synuclein; Autophagy; Endoplasmic Reticulum Stress; Gene Expression Regulation; HEK293 Cells; Humans; Indazoles; Indoles; Parkinson Disease; Proto-Oncogene Proteins c-akt

2021