indazoles has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 11 (84.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giranda, VL; Han, EK; Hunter, T; Leverson, JD; Luo, Y; McGonigal, T; Shah, OJ; Woods, KW | 1 |
| Cheng, WH; Chiang, HT; Hsiao, M; Huang, HN; Lo, WC; Lu, PJ; Tseng, CJ; Tseng, YC; Wang, JL | 1 |
| Dan, S; Kong, D; Yamazaki, K; Yamori, T | 1 |
| Bai, C; Chen, C; Fang, X; Li, Y; Wang, D; Wang, X; Wang, Y; Zhao, X | 1 |
| Jiao, M; Nan, KJ | 1 |
| Cao, J; Guo, B; Liang, D; Yang, L; Yang, M; Zhang, X | 1 |
| Bartsch, S; Klettner, A; Lassen, J; Roider, J; Westhues, D | 1 |
| Andreeff, M; Jin, L; Kimura, S; Konopleva, M; Miida, T; Raffeld, M; Shikami, M; Tabe, Y | 1 |
| Dixon, SJ; Jirik, FR; Kashishian, A; Lannutti, BJ; Pereverzev, A; Puri, KD; Shugg, RP; Sims, SM; Steiner, BH; Tanabe, N; Thomson, A | 1 |
| Corson, JM; Eilers, G; Fletcher, JA; Kuang, Y; Li, H; Li, X; Liu, L; Meng, F; Ou, WB; Sheng, Q; Shi, S; Yan, Z; Zhou, H; Zhou, S | 1 |
| Kazi, JU; Lindblad, O; Rönnstrand, L; Sun, J | 1 |
| Chen, KH; Curtis, J; Dasgupta, A; Ghosh, P; Longo, DL; Munk, RB; Sasaki, CY | 1 |
| Fu, X; Halim, A; Luo, Q; Song, G; Tian, B | 1 |
13 other study(ies) available for indazoles and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one
| Article | Year |
|---|---|
Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition.
Topics: Cell Line, Tumor; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Immunoblotting; Indazoles; Indoles; Mechanistic Target of Rapamycin Complex 1; Morpholines; Multiprotein Complexes; Mutation; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proteins; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Serine; Time Factors; TOR Serine-Threonine Kinases; Transcription Factors; Transfection; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins | 2007 |
Neuronal nitric oxide synthase activation is involved in insulin-mediated cardiovascular effects in the nucleus tractus solitarii of rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Chromones; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heart Rate; Immunoprecipitation; Indazoles; Insulin; Male; Microinjections; Morpholines; Nitric Oxide Synthase Type I; Ornithine; Rats; Rats, Inbred WKY; Solitary Nucleus | 2009 |
Inhibition profiles of phosphatidylinositol 3-kinase inhibitors against PI3K superfamily and human cancer cell line panel JFCR39.
Topics: Algorithms; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Chromones; Drug Screening Assays, Antitumor; Humans; Imidazoles; Indazoles; Morpholines; Neoplasms; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinolines; Substrate Specificity; Sulfonamides; Triazines | 2010 |
Preventive and therapeutic effects of phosphoinositide 3-kinase inhibitors on acute lung injury.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Chromones; Epithelial Cells; Indazoles; Leukocytes; Lipopolysaccharides; Male; Mice; Mice, Inbred Strains; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Rats; Rats, Wistar; Signal Transduction; Sulfonamides | 2011 |
Activation of PI3 kinase/Akt/HIF-1α pathway contributes to hypoxia-induced epithelial-mesenchymal transition and chemoresistance in hepatocellular carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Movement; Cell Survival; Chromones; Cisplatin; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression; Genes, MDR; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Liver Neoplasms; Male; Mice; Mice, Nude; Morpholines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays | 2012 |
HIF-1α induced by β-elemene protects human osteosarcoma cells from undergoing apoptosis.
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Microscopy, Fluorescence; Morpholines; Osteosarcoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; RNA Interference; Sesquiterpenes; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases | 2012 |
Regulation of constitutive vascular endothelial growth factor secretion in retinal pigment epithelium/choroid organ cultures: p38, nuclear factor κB, and the vascular endothelial growth factor receptor-2/phosphatidylinositol 3 kinase pathway.
Topics: Animals; Choroid; Chromones; Cinnamates; Cyclic S-Oxides; Imidazoles; Indazoles; Indoles; Maleimides; MAP Kinase Signaling System; Morpholines; NF-kappa B; Organ Culture Techniques; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Plicamycin; Pyridines; Retinal Pigment Epithelium; Signal Transduction; Sus scrofa; Transcription Factors; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2013 |
Class IA PI3K inhibition inhibits cell growth and proliferation in mantle cell lymphoma.
Topics: Cell Cycle; Cell Proliferation; Chromones; Humans; Indazoles; Lymphoma, Mantle-Cell; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidinones; Sulfonamides | 2014 |
Effects of isoform-selective phosphatidylinositol 3-kinase inhibitors on osteoclasts: actions on cytoskeletal organization, survival, and resorption.
Topics: Adenine; Androstadienes; Animals; Bone Resorption; Cell Survival; Chromones; Cytoskeleton; Indazoles; Isoenzymes; Morpholines; Osteoclasts; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinazolines; Rabbits; RANK Ligand; Rats; Sulfonamides; Wortmannin | 2013 |
Multipoint targeting of the PI3K/mTOR pathway in mesothelioma.
Topics: Antineoplastic Agents; Butadienes; Cell Cycle; Cell Line, Tumor; Chromones; Drug Screening Assays, Antitumor; Enzyme Activation; Everolimus; Humans; Imidazoles; Indazoles; MAP Kinase Signaling System; Mesothelioma; Molecular Targeted Therapy; Morpholines; Neoplasm Proteins; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinolines; raf Kinases; Receptor Protein-Tyrosine Kinases; RNA Interference; RNA, Small Interfering; Signal Transduction; Sirolimus; Sulfonamides; TOR Serine-Threonine Kinases | 2014 |
PI3 kinase is indispensable for oncogenic transformation by the V560D mutant of c-Kit in a kinase-independent manner.
Topics: Animals; Blotting, Western; Cell Line; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Chromones; HEK293 Cells; Humans; Indazoles; Indoles; Morpholines; Mutation, Missense; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-kit; Signal Transduction; src-Family Kinases; Stem Cell Factor; Sulfonamides | 2015 |
Mechanism of Activation-Induced Downregulation of Mitofusin 2 in Human Peripheral Blood T Cells.
Topics: Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromones; Down-Regulation; GTP Phosphohydrolases; Humans; Indazoles; Indoles; Leukocytes, Mononuclear; Lymphocyte Activation; Mitochondrial Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Sirolimus; T-Lymphocytes; TOR Serine-Threonine Kinases | 2015 |
MT1-MMP downregulation via the PI3K/Akt signaling pathway is required for the mechanical stretching-inhibited invasion of bone-marrow-derived mesenchymal stem cells.
Topics: Animals; Cell Differentiation; Cell Movement; Cell Proliferation; Chromones; Gene Expression Regulation, Developmental; Humans; Indazoles; Indoles; Matrix Metalloproteinase 14; Mesenchymal Stem Cells; Morpholines; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Signal Transduction; Stress, Mechanical | 2019 |