Compounds > indatraline
Page last updated: 2024-09-03

indatraline and vx-745

indatraline has been researched along with vx-745 in 2 studies

Compound Research Comparison

Studies
(indatraline)		Trials
(indatraline)		Recent Studies (post-2010)
(indatraline)		Studies
(vx-745)		Trials
(vx-745)		Recent Studies (post-2010) (vx-745)
4602458135

Protein Interaction Comparison

ProteinTaxonomyindatraline (IC50)vx-745 (IC50)
Mitogen-activated protein kinase 13Homo sapiens (human)0.0577
Bile salt export pumpHomo sapiens (human)10
Tyrosine-protein kinase ABL1Homo sapiens (human)1
Cytochrome P450 3A4Homo sapiens (human)0.0008
Platelet-derived growth factor receptor betaHomo sapiens (human)1
Adenosine receptor A3Homo sapiens (human)8.547
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)1
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)8.547
Amine oxidase [flavin-containing] BRattus norvegicus (Norway rat)0.029
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0008
Tyrosine-protein kinase ABL2Homo sapiens (human)1
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)8.547
Mitogen-activated protein kinase 14 Mus musculus (house mouse)0.0442
Mitogen-activated protein kinase 12Homo sapiens (human)0.0577
Sodium-dependent dopamine transporter Homo sapiens (human)8.098
Mitogen-activated protein kinase 11Homo sapiens (human)0.2462
Mitogen-activated protein kinase 14Homo sapiens (human)0.4028

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1

Other Studies

2 other study(ies) available for indatraline and vx-745

ArticleYear
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020