Page last updated: 2024-09-03

indanidine and nifedipine

indanidine has been researched along with nifedipine in 6 studies

Compound Research Comparison

Studies
(indanidine)
Trials
(indanidine)
Recent Studies (post-2010)
(indanidine)
Studies
(nifedipine)
Trials
(nifedipine)
Recent Studies (post-2010) (nifedipine)
260116,0242,4961,505

Protein Interaction Comparison

ProteinTaxonomyindanidine (IC50)nifedipine (IC50)
perilipin-5Homo sapiens (human)7.133
perilipin-1Homo sapiens (human)9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)8.376
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.0429
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.035
Cytochrome P450 1A2Homo sapiens (human)0.3
Cytochrome P450 3A4Homo sapiens (human)10
Adenosine receptor A3Homo sapiens (human)7.214
Cytochrome P450 2C9 Homo sapiens (human)3.06
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.214
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0385
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)1.12
Adenosine receptor A1Homo sapiens (human)7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)1.12
C-C chemokine receptor type 2Homo sapiens (human)2.191
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.214
Cytochrome P450 2J2Homo sapiens (human)3.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.4733
Voltage-dependent L-type calcium channel subunit alpha-1CMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.035
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0394
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.02
Potassium channel subfamily K member 2 Bos taurus (cattle)8.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)1.5
Voltage-dependent L-type calcium channel subunit alpha-1DMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1FMus musculus (house mouse)1.2

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B1
McGrath, JC1
de Jonge, A; Mathy, MJ; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B2
Hong, KW; Jung, HO1
Hart, SD; Timmermans, PB; Wong, PC1

Other Studies

6 other study(ies) available for indanidine and nifedipine

ArticleYear
Calcium dependency of vasoconstriction mediated by alpha 1- and alpha 2-adrenoceptors.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Azepines; Blood Pressure; Calcium; Calcium Channel Blockers; Clonidine; Imidazoles; Ion Channels; Nifedipine; Rats; Receptors, Adrenergic, alpha; Regional Blood Flow; Structure-Activity Relationship; Vasoconstriction

1985
alpha-Adrenoceptor agonists and the Ca2+-dependence of smooth muscle contraction: evidence for subtypes of receptors or for agonist-dependent differences in the agonist-receptor interaction?
    Clinical science (London, England : 1979), 1985, Volume: 68 Suppl 10

    Topics: Adrenergic alpha-Agonists; Animals; Calcium; Clonidine; Ethanolamines; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Nifedipine; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Xylazine

1985
Effects of the irreversible alpha-adrenoceptor antagonists phenoxybenzamine and benextramine on the effectiveness of nifedipine in inhibiting alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in pithed rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:4

    Topics: Animals; Azepines; Clonidine; Cystamine; Decerebrate State; Diastole; Dose-Response Relationship, Drug; Imidazoles; Male; Nifedipine; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction

1985
Characterization of inhibition by nifedipine and nitroprusside of the pressor responses to alpha 1-adrenoceptor agonists cirazoline and Sgd 101/75 in pithed rats.
    Yonsei medical journal, 1988, Volume: 29, Issue:2

    Topics: Animals; Blood Pressure; Clonidine; Ferricyanides; Imidazoles; Male; Nifedipine; Nitroprusside; Rats; Rats, Inbred Strains; Vasoconstriction

1988
Sgd 101/75 is distinguished from other selective alpha 1-adrenoceptor agonists by the inhibition of its pressor responses by calcium entry blockade and vasodilatation in pithed rats and cats.
    European journal of pharmacology, 1983, Dec-23, Volume: 96, Issue:3-4

    Topics: Adrenergic alpha-Agonists; Albuterol; Animals; Blood Pressure; Calcium Channel Blockers; Cats; Clonidine; Decerebrate State; Dose-Response Relationship, Drug; Male; Nifedipine; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilation

1983
Effects of nifedipine on phasic and tonic vasoconstrictor responses to Sgd 101/75 in the isolated perfused rabbit ear artery.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: Adrenergic alpha-Agonists; Animals; Arteries; Calcium; Clonidine; Ear; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Vasoconstriction

1994