impletol has been researched along with caffeine in 38 studies
*Caffeine: A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling. [MeSH]
*Caffeine: A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling. [MeSH]
| Studies (impletol) | Trials (impletol) | Recent Studies (post-2010) (impletol) | Studies (caffeine) | Trials (caffeine) | Recent Studies (post-2010) (caffeine) |
|---|---|---|---|---|---|
| 41 | 0 | 0 | 25,501 | 2,393 | 6,825 |
| Protein | Taxonomy | impletol (IC50) | caffeine (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Homo sapiens (human) | 7.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kubo, M; Sakakura, Y; Yamagiwa, M | 1 |
| VON FRESENIUS, H | 1 |
| HABER, H | 1 |
| HUNEKE, F | 3 |
| MANFREDI, E | 1 |
| GROHER, H | 1 |
| DAMMANN, F | 1 |
| WEDIG, K | 1 |
| NIGGEMEYER, H | 1 |
| BAKER, A | 1 |
| BUCHSEL, HW | 1 |
| GAERTNER, W | 1 |
| DEL TORTO, U; JANNELLI, E | 1 |
| HACKL, G | 1 |
| COLLISCHONN, P | 1 |
| STERN, P | 1 |
| FINKE, H | 1 |
| DOSCH, JP | 1 |
| LEIMSNER, K | 1 |
| GALIANA, JC | 1 |
| GESELL-PAYER, A | 1 |
| KELLERMANN, J | 1 |
| RZYMANN, G | 1 |
| KIRSCH, T | 1 |
| HAUBEIL, J | 2 |
| PLESTER, D | 2 |
| WACHTER, H | 1 |
| BAUMANN, W | 1 |
| LOHR, B | 1 |
| HUNEKE, W | 2 |
| NICOLAI, W | 1 |
| KALDEN, E | 1 |
| HUBERT, G | 1 |
38 other study(ies) available for impletol and caffeine
| Article | Year |
|---|---|
[Effect of Impletol injection into paratonsillar tissue on abnormal sensation in the throat].
Topics: Adult; Aged; Caffeine; Drug Combinations; Female; Humans; Injections; Male; Middle Aged; Palatine Tonsil; Pharyngeal Diseases; Procaine; Sensation | 1989 |
[Therapeutic significance of impletol].
Topics: Arthritis; Arthritis, Rheumatoid; Caffeine; Cold Temperature; Cryotherapy; Drug Combinations; Humans; Procaine | 1952 |
[Thoughts and questions on neural therapy with impletol].
Topics: Caffeine; Drug Combinations; Humans; Nervous System Diseases; Procaine | 1953 |
[Pain therapy with impletol].
Topics: Caffeine; Drug Combinations; Pain Management; Procaine | 1953 |
[Our remote results after local treatment of parametrium diseases with impletol and antibiotics].
Topics: Anti-Bacterial Agents; Caffeine; Disease; Drug Combinations; Female; Humans; Procaine; Uterine Diseases; Uterus | 1953 |
[Experiences in the treatment of gynecological diseases with impletol].
Topics: Caffeine; Drug Combinations; Female; Genital Diseases, Female; Humans; Procaine | 1953 |
[Surgical application of impletol and depot impletol].
Topics: Caffeine; Drug Combinations; Humans; Procaine | 1953 |
[Usefulness of the impletol or jecoffin test in metastasizing dental infection].
Topics: Caffeine; Communicable Diseases; Drug Combinations; Focal Infection; Humans; Procaine | 1953 |
[Impletol therapy in infantile paralysis].
Topics: Caffeine; Drug Combinations; Poliomyelitis; Procaine | 1953 |
[Therapeutic anesthesia with depot impletol].
Topics: Anesthesia; Caffeine; Drug Combinations; Humans; Procaine | 1953 |
[Impletol therapy of erroneous paravenous injection].
Topics: Caffeine; Drug Combinations; Humans; Injections; Procaine | 1954 |
[Local impletol in the differential diagnosis of torsions of the knee].
Topics: Analgesia; Anesthesia; Anesthesia and Analgesia; Caffeine; Diagnosis, Differential; Drug Combinations; Knee Injuries; Procaine; Wounds and Injuries | 1954 |
[Therapeutic possibility of impletol in motor changes of nervous origin].
Topics: Anxiety; Caffeine; Drug Combinations; Humans; Paralysis; Procaine | 1954 |
[The right place for impletol depot injections].
Topics: Caffeine; Drug Combinations; Humans; Injections; Procaine | 1954 |
[An allergic skin reaction to impletol].
Topics: Caffeine; Drug Combinations; Drug Eruptions; Humans; Hypersensitivity; Procaine | 1954 |
[Treatment of tenosynovitis with impletol as a social indication and the necessity of its recognition as occupational disease].
Topics: Caffeine; Drug Combinations; Humans; Occupational Diseases; Procaine; Tenosynovitis | 1954 |
[The treatment of spastic paralysis with intratendonous impletol injections].
Topics: Caffeine; Drug Combinations; Humans; Injections; Multiple Sclerosis; Muscle Spasticity; Paralysis; Procaine | 1954 |
[Treatment of organic and functional heart diseases with impletol].
Topics: Caffeine; Drug Combinations; Heart Diseases; Heart Failure; Procaine; Therapeutics | 1955 |
[Successful results of impletol in general practice].
Topics: Caffeine; Drug Combinations; General Practice; Procaine | 1956 |
[Therapy of so-called cardiospasm; esophagoscopic cardial injection of impletol].
Topics: Caffeine; Drug Combinations; Esophageal Achalasia; Esophagoscopy; Humans; Procaine; Punctures | 1956 |
[Treatment of various forms of rheumatism with impletol].
Topics: Caffeine; Drug Combinations; Humans; Procaine; Rheumatic Diseases | 1957 |
[Alopecia and impletol].
Topics: Alopecia; Caffeine; Drug Combinations; Procaine | 1960 |
[Impletol therapy of inflammatory processes and arthroses of the extremities].
Topics: Caffeine; Disease; Drug Combinations; Extremities; Humans; Joint Diseases; Osteoarthritis; Procaine | 1960 |
[Impletol for pains of various origin. A casuistic contribution to the topic of neural therapy].
Topics: Caffeine; Drug Combinations; Pain Management; Procaine | 1959 |
[Experiences with depot impletol in sports injuries].
Topics: Athletic Injuries; Caffeine; Drug Combinations; Humans; Procaine; Psychotherapy; Wounds and Injuries | 1960 |
[Results of therapeutic use of impletol in stomatology; case reports].
Topics: Anesthesia; Caffeine; Dentistry; Drug Combinations; Humans; Neuralgia; Oral Medicine; Procaine | 1950 |
[Distant effects of gingival injections of impletol].
Topics: Caffeine; Drug Combinations; Focal Infection; Procaine | 1951 |
[Various effects of impletol injections in the gums].
Topics: Anesthesia; Caffeine; Drug Combinations; Gingiva; Humans; Procaine | 1951 |
[In explanation of the mode of action of novocaine (impletol) in circulatory disorders].
Topics: Blood Circulation; Caffeine; Drug Combinations; Frostbite; Procaine | 1951 |
[Subcutaneous impletol injections in the upper abdomen in severe nose bleeds].
Topics: Abdomen; Caffeine; Drug Combinations; Epistaxis; Homeopathy; Humans; Injections, Subcutaneous; Procaine | 1951 |
[On the pathogenesis and therapy of myocardial infarct, with special reference to the author's experience with injections of impletol and strophanthin].
Topics: Caffeine; Coronary Disease; Drug Combinations; Humans; Myocardial Infarction; Procaine; Strophanthins | 1951 |
[Preparation for bronchography and local anesthesia of the bronchial tree with special reference to premedication with impletol].
Topics: Anesthesia, Local; Bronchography; Caffeine; Drug Combinations; Humans; Lung; Procaine; Trees | 1952 |
[Neural therapy with and without impletol].
Topics: Caffeine; Drug Combinations; Humans; Pain Management; Procaine | 1951 |
[Experimental investigations of the effect of novocain & impletol on peripheral vascular diseases].
Topics: Caffeine; Drug Combinations; Humans; Peripheral Vascular Diseases; Procaine | 1951 |
[Focal diagnosis with impletol injections].
Topics: Caffeine; Drug Combinations; Focal Infection; Procaine | 1952 |
[Neural therapy with and without impletol].
Topics: Caffeine; Drug Combinations; Humans; Procaine | 1951 |
[Acute inflammation of the temporomandibular joint treated with impletol].
Topics: Caffeine; Drug Combinations; Humans; Inflammation; Jaw; Procaine; Temporomandibular Joint | 1950 |
Self-observations on the effects of impletol treatment.
Topics: Caffeine; Drug Combinations; Procaine | 1948 |