imirestat has been researched along with tolrestat in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DuPriest, MT; Griffin, BW; Kuzmich, D; McNatt, LG | 1 |
| Carper, DA; Hohman, TC; Kitchen, D; Malamas, MS; Nilakantan, R; Singh, SB | 1 |
| Matsuura, Y; Nishimura, C; Tanimoto, T; Yamaoka, T; Yamashita, K | 1 |
| Chang, K; Eades, DM; Kilo, C; Province, MA; Pugliese, G; Sherman, WR; Tilton, RG; Williamson, JR | 1 |
| Bannai, C; Itakura, M; Oda, A; Yamaoka, T; Yamashita, K | 1 |
| Lou, MF; Xu, GT; York, B; Zigler, S | 1 |
| Carper, D; Sato, S; Sugiyama, K | 1 |
| Kador, PF; Lee, YS; Sato, S; Sugiyama, K | 1 |
| Chen, Z; Kador, PF; Lee, YS; Sugiyama, K | 1 |
| Blessing, K; Fujisawa, S; Kador, PF; Lee, JW; Lou, MF | 1 |
| Blessing, K; Kador, PF; Marx, DB; O'Meara, JD; Reinhardt, RA | 1 |
| Kador, PF; Zhang, P; Zhang, Z | 1 |
12 other study(ies) available for imirestat and tolrestat
| Article | Year |
|---|---|
Spiro[fluoreneisothiazolidin]one dioxides: new aldose reductase and L-hexonate dehydrogenase inhibitors.
Topics: Aldehyde Reductase; Animals; Carbohydrate Dehydrogenases; Enzyme Inhibitors; Rats; Spiro Compounds; Structure-Activity Relationship; Thiazoles | 1991 |
Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants.
Topics: Aldehyde Reductase; Benzothiazoles; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phthalazines; Recombinant Proteins; Structure-Activity Relationship; Thiazoles | 2000 |
Site-directed mutagenesis of His-42, His-188 and Lys-263 of human aldose reductase.
Topics: Aldehyde Reductase; Amino Acid Sequence; Base Sequence; Binding Sites; Cloning, Molecular; Fluorenes; Humans; Hydantoins; Imidazoles; Imidazolidines; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NADP; Naphthalenes; Structure-Activity Relationship | 1992 |
Prevention of hemodynamic and vascular albumin filtration changes in diabetic rats by aldose reductase inhibitors.
Topics: Albuminuria; Aldehyde Reductase; Animals; Cardiac Output; Diabetes Mellitus, Experimental; Fluorenes; Glomerular Filtration Rate; Hemodynamics; Hydantoins; Imidazoles; Imidazolidines; Iodine Radioisotopes; Male; Naphthalenes; Rats; Rats, Inbred Strains; Reference Values; Regional Blood Flow; Serum Albumin, Bovine; Sorbitol; Strontium; Sugar Alcohol Dehydrogenases; Vascular Resistance | 1989 |
The effect of non-enzymatic glycation on recombinant human aldose reductase.
Topics: Aldehyde Reductase; Enzyme Inhibitors; Fluorenes; Glucose; Glycosylation; Humans; Hydantoins; Imidazoles; Imidazolidines; Kinetics; Naphthalenes; Phthalazines; Recombinant Proteins; Substrate Specificity; Transfection | 1995 |
Inhibition of naphthalene cataract in rats by aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cataract; Culture Techniques; Disease Models, Animal; Enzyme Inhibitors; Fluorenes; Galactose; Hydantoins; Imidazoles; Imidazolidines; Male; Naphthalenes; Rats; Spiro Compounds | 1996 |
Aldose reductase as dihydrodiol dehydrogenase. Naphthoquinone formation by rat lens aldose reductase.
Topics: Aldehyde Reductase; Animals; Enzyme Inhibitors; Eye Proteins; Fluorenes; Hydantoins; Imidazoles; Imidazolidines; Lens, Crystalline; Naphthalenes; Naphthoquinones; Oxidoreductases; Phthalazines; Rats | 1997 |
Prevention of naphthalene-1,2-dihydrodiol-induced lens protein modifications by structurally diverse aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cataract; Chromatography, High Pressure Liquid; Crystallins; Enzyme Inhibitors; Fluorenes; Hydantoins; Imidazoles; Imidazolidines; Lens, Crystalline; Naphthalenes; Naphthols; Naphthoquinones; Phthalazines; Rats; Spectrophotometry | 1999 |
Isolation of a non-covalent aldose reductase-nucleotide-inhibitor complex.
Topics: Aldehyde Reductase; Animals; Enzyme Inhibitors; Fluorenes; Humans; Hydantoins; Lens, Crystalline; Models, Molecular; Muscles; NADP; Naphthalenes; Phthalazines; Rats | 2000 |
Relative importance of aldose reductase versus nonenzymatic glycosylation on sugar cataract formation in diabetic rats.
Topics: Aldehyde Reductase; Animals; Cataract; Crystallins; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fluorenes; Glutathione; Glycation End Products, Advanced; Glycosylation; Hydantoins; Lens, Crystalline; Naphthalenes; Phthalazines; Rats; Rats, Sprague-Dawley; Sorbitol; Spectrometry, Fluorescence | 2000 |
Efficacy of structurally diverse aldose reductase inhibitors on experimental periodontitis in rats.
Topics: Aldehyde Reductase; Alveolar Bone Loss; Animals; Antioxidants; Citric Acid Cycle; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fluorenes; Glycolysis; Hydantoins; Lipopolysaccharides; Male; Naphthalenes; Periodontitis; Quercetin; Rats; Rats, Sprague-Dawley; Sorbitol | 2011 |
Polyol effects on growth factors and MAPK signaling in rat retinal capillary cells.
Topics: Aldehyde Reductase; Animals; Capillaries; Cell Line; Endothelial Cells; Fluorenes; Galactitol; Galactose; Glucose; Hydantoins; Intercellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Naphthalenes; Pericytes; Rats; Rats, Transgenic; Retinal Vessels; Sorbitol | 2014 |