imirestat has been researched along with ponalrestat in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DuPriest, MT; Griffin, BW; Kuzmich, D; McNatt, LG | 1 |
| Carper, DA; Hohman, TC; Kitchen, D; Malamas, MS; Nilakantan, R; Singh, SB | 1 |
| Banfield, CR; Brazzell, RK; Chien, JY; Mayer, PR; Slattery, JT | 1 |
| Kador, PF; Sato, S | 1 |
| Bannai, C; Itakura, M; Oda, A; Yamaoka, T; Yamashita, K | 1 |
| Carper, D; Sato, S; Sugiyama, K | 1 |
| Blessing, K; Greentree, W; Inoue, J; Kador, PF; Lackner, PA; Lizak, MJ; Mori, K; Rodriguez, L; Sato, S; Secchi, EF | 1 |
| Kador, PF; Lee, YS; Sato, S; Sugiyama, K | 1 |
| Chen, Z; Kador, PF; Lee, YS; Sugiyama, K | 1 |
| Blessing, K; Fujisawa, S; Kador, PF; Lee, JW; Lou, MF | 1 |
10 other study(ies) available for imirestat and ponalrestat
| Article | Year |
|---|---|
Spiro[fluoreneisothiazolidin]one dioxides: new aldose reductase and L-hexonate dehydrogenase inhibitors.
Topics: Aldehyde Reductase; Animals; Carbohydrate Dehydrogenases; Enzyme Inhibitors; Rats; Spiro Compounds; Structure-Activity Relationship; Thiazoles | 1991 |
Molecular modeling of the aldose reductase-inhibitor complex based on the X-ray crystal structure and studies with single-site-directed mutants.
Topics: Aldehyde Reductase; Benzothiazoles; Binding Sites; Crystallography, X-Ray; Enzyme Inhibitors; Humans; Models, Molecular; Mutagenesis, Site-Directed; Phthalazines; Recombinant Proteins; Structure-Activity Relationship; Thiazoles | 2000 |
Saturable tissue binding and imirestat pharmacokinetics in rats.
Topics: Aldehyde Reductase; Animals; Fluorenes; Hydantoins; Male; Phthalazines; Rats; Rats, Inbred Strains; Tissue Distribution | 1992 |
Inhibition of aldehyde reductase by aldose reductase inhibitors.
Topics: Alcohol Dehydrogenase; Aldehyde Reductase; Animals; Cells, Cultured; Fluorenes; Hydantoins; Isoquinolines; Kidney; Kinetics; Lens, Crystalline; Phthalazines; Pyridazines; Rats; Structure-Activity Relationship; Substrate Specificity; Sugar Alcohol Dehydrogenases | 1990 |
The effect of non-enzymatic glycation on recombinant human aldose reductase.
Topics: Aldehyde Reductase; Enzyme Inhibitors; Fluorenes; Glucose; Glycosylation; Humans; Hydantoins; Imidazoles; Imidazolidines; Kinetics; Naphthalenes; Phthalazines; Recombinant Proteins; Substrate Specificity; Transfection | 1995 |
Aldose reductase as dihydrodiol dehydrogenase. Naphthoquinone formation by rat lens aldose reductase.
Topics: Aldehyde Reductase; Animals; Enzyme Inhibitors; Eye Proteins; Fluorenes; Hydantoins; Imidazoles; Imidazolidines; Lens, Crystalline; Naphthalenes; Naphthoquinones; Oxidoreductases; Phthalazines; Rats | 1997 |
Effect of sorbitol dehydrogenase inhibition on sugar cataract formation in galactose-fed and diabetic rats.
Topics: Aldehyde Reductase; Animals; Cataract; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Fluorenes; Galactose; Hydantoins; L-Iditol 2-Dehydrogenase; Phthalazines; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley | 1998 |
Prevention of naphthalene-1,2-dihydrodiol-induced lens protein modifications by structurally diverse aldose reductase inhibitors.
Topics: Aldehyde Reductase; Animals; Cataract; Chromatography, High Pressure Liquid; Crystallins; Enzyme Inhibitors; Fluorenes; Hydantoins; Imidazoles; Imidazolidines; Lens, Crystalline; Naphthalenes; Naphthols; Naphthoquinones; Phthalazines; Rats; Spectrophotometry | 1999 |
Isolation of a non-covalent aldose reductase-nucleotide-inhibitor complex.
Topics: Aldehyde Reductase; Animals; Enzyme Inhibitors; Fluorenes; Humans; Hydantoins; Lens, Crystalline; Models, Molecular; Muscles; NADP; Naphthalenes; Phthalazines; Rats | 2000 |
Relative importance of aldose reductase versus nonenzymatic glycosylation on sugar cataract formation in diabetic rats.
Topics: Aldehyde Reductase; Animals; Cataract; Crystallins; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fluorenes; Glutathione; Glycation End Products, Advanced; Glycosylation; Hydantoins; Lens, Crystalline; Naphthalenes; Phthalazines; Rats; Rats, Sprague-Dawley; Sorbitol; Spectrometry, Fluorescence | 2000 |