imiquimod has been researched along with methotrexate in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (13.04) | 29.6817 |
| 2010's | 12 (52.17) | 24.3611 |
| 2020's | 8 (34.78) | 2.80 |
| Authors | Studies |
|---|---|
| Bonnard, V; Bonnet, PA; Bressolle, F; Deleuze-Masquefa, C; Gayraud-Paniagua, S; Moarbess, G; Pinguet, F; Vidal, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Beyeler, M; Dummer, R | 1 |
| Dixon, A | 1 |
| Chitwood, K; Cohen, G; Etzkorn, J | 1 |
| Bielsa Marsol, I | 1 |
| Haddad, E; Hatami, A; Marcoux, D; McCuaig, CC; Piram, M; Powell, J; Saint-Cyr, C | 1 |
| Byamba, D; Jee, H; Kim, DS; Kim, DY; Kim, SH; Kim, TG; Lee, MG; Lee, SK; Park, TY; Yang, SH | 1 |
| Macknet, C; Macknet, KD; Nino, T; Panther, D | 1 |
| Fabi, SG; Zaleski-Larsen, LA | 1 |
| Panonnummal, R; Sabitha, M | 1 |
| Chen, W; Jia, X; Kuang, Y; Liao, L; Lu, Y; Qin, Q; Wu, L; Zhang, H; Zhu, W | 1 |
| Di, T; Li, N; Li, P; Li, X; Liu, Z; Meng, Y; Wang, M; Xie, X; Zhai, C; Zhang, L | 1 |
| Feng, L; Guo, M; Huang, W; Kong, L; Shao, F; Song, P; Wu, X; Xu, F; Xu, L; Xu, Q | 1 |
| Bahramizadeh, M; Esmaily, H; Golmohammadzadeh, S; Hatamipour, M; Jafari, MR; Jafarian, AH; Kiafar, B; Moosavian, SA; Nikpoor, AR; Rezaeemehr, Z | 1 |
| Akdis, CA; Boyman, O; Hafner, J; Impellizzieri, D; Kolios, AGA; Kurzbach, D; Nguyen, TT; Nilsson, J; Özcan, A; Sahin, D; Tan, G; Yawalkar, N | 1 |
| Agrawal, YO; Mahajan, HS; Mahajan, UB; Ojha, S | 1 |
| Daou, H; Hatch, LA; Messina, J; Morey, GE; Seminario-Vidal, L; Sokol, L; Weinkle, A; Zhang, X | 1 |
| Chen, Y; Dai, Z; Han, L; Huang, RY; Liang, CL; Liu, H; Lu, C; Qiu, F; Yan, Y; Zhang, Q | 1 |
| Pang, M; Tang, Y; Wang, M; Wang, W; Wang, Y; Xu, Y; Yang, X | 1 |
| Agostini, SBN; Alves, CO; Bernardes, MTCP; Carvalho, FC; da Silva, LP; Gonçalves, RV; Novaes, RD; Pereira, GR | 1 |
| Cha, X; Chen, Y; Lai, B; Tao, T; Wang, J; Wang, W; Xiao, W | 1 |
| Jiang, D; Li, J; Lyu, Y; Wu, D; Xin, X; Yang, L; Yin, L; Zhou, Y; Zhu, Y | 1 |
4 review(s) available for imiquimod and methotrexate
| Article | Year |
|---|---|
[Standard and experimental therapy of cutaneous T-cell lymphoma].
Topics: Adrenal Cortex Hormones; Aminoquinolines; Antibiotics, Antineoplastic; Anticarcinogenic Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bexarotene; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Humans; Imiquimod; Interferon alpha-2; Interferon-alpha; Lymphoma, T-Cell; Methotrexate; Photopheresis; Prednisone; PUVA Therapy; Radioisotope Teletherapy; Radiotherapy Dosage; Radiotherapy, High-Energy; Recombinant Proteins; Retinoids; Skin Neoplasms; Tetrahydronaphthalenes; Vincristine | 2003 |
Topical and intralesional treatment of nonmelanoma skin cancer: efficacy and cost comparisons.
Topics: Administration, Cutaneous; Aminoquinolines; Antineoplastic Agents; Bleomycin; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Fluorouracil; Humans; Imiquimod; Injections, Intralesional; Interferon alpha-2; Interferon-alpha; Keratoacanthoma; Methotrexate; Recombinant Proteins; Skin Neoplasms | 2013 |
Update on the classification and treatment of localized scleroderma.
Topics: Algorithms; Aminoquinolines; Clinical Trials as Topic; Eosinophilia; Fasciitis; Glucocorticoids; Humans; Imiquimod; Immunosuppressive Agents; Methotrexate; Photochemotherapy; Physical Therapy Modalities; Recurrence; Scleroderma, Localized; Severity of Illness Index | 2013 |
Laser-Assisted Drug Delivery.
Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Aminolevulinic Acid; Aminoquinolines; Analgesics; Antibodies; Antineoplastic Agents; Ascorbic Acid; Cyclopropanes; Dermatologic Agents; Drug Delivery Systems; Fluorouracil; Humans; Imiquimod; Immunotherapy; Laser Therapy; Methotrexate; Minoxidil; Permeability; Photosensitizing Agents; Polyesters; RNA, Small Interfering; Skin; Timolol; Vaccines | 2016 |
19 other study(ies) available for imiquimod and methotrexate
| Article | Year |
|---|---|
In vitro and in vivo anti-tumoral activities of imidazo[1,2-a]quinoxaline, imidazo[1,5-a]quinoxaline, and pyrazolo[1,5-a]quinoxaline derivatives.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Databases, Factual; Female; Humans; Imidazoles; Mice; Mice, Nude; Molecular Structure; Pyrazoles; Quinoxalines; Xenograft Model Antitumor Assays | 2008 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Check Program.
Topics: Aminoquinolines; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bowen's Disease; Humans; Imiquimod; Keratoacanthoma; Methotrexate | 2007 |
Short- and long-term outcome of linear morphoea in children.
Topics: Adolescent; Adrenal Cortex Hormones; Age of Onset; Aminoquinolines; Calcitriol; Child; Dermatologic Agents; Drug Therapy, Combination; Female; Humans; Imiquimod; Male; Methotrexate; Ointments; Phototherapy; Retrospective Studies; Scleroderma, Localized; Tacrolimus; Treatment Outcome; Vitamin A; Vitamin E | 2013 |
Skin-penetrating methotrexate alleviates imiquimod-induced psoriasiform dermatitis via decreasing IL-17-producing gamma delta T cells.
Topics: Aminoquinolines; Animals; CD11c Antigen; CD4-Positive T-Lymphocytes; Cytokines; Dermatitis; DNA, Complementary; Female; Imiquimod; Inflammation; Interleukin-17; Interleukin-23; Methotrexate; Mice; Mice, Inbred BALB C; Peptides; Permeability; Psoriasis; Skin | 2014 |
Eruptive keratoacanthomas as a complication of fractionated CO2 laser resurfacing and combination therapy with imiquimod and intralesional methotrexate.
Topics: Administration, Cutaneous; Aged; Aminoquinolines; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Imiquimod; Injections, Intralesional; Keratoacanthoma; Lasers, Gas; Methotrexate; Rejuvenation; Skin Neoplasms | 2015 |
Anti-psoriatic and toxicity evaluation of methotrexate loaded chitin nanogel in imiquimod induced mice model.
Topics: Aminoquinolines; Animals; Chitin; Disease Models, Animal; Drug Delivery Systems; Humans; Imiquimod; Methotrexate; Mice; Mice, Inbred BALB C; Nanoparticles; Psoriasis; THP-1 Cells | 2018 |
[Effect of methotrexate on regulation for the number of regulatory T cells and expression of Foxp3 in psoriasis].
Topics: Adjuvants, Immunologic; Aminoquinolines; Animals; Case-Control Studies; Female; Forkhead Transcription Factors; Humans; Imiquimod; Immunosuppressive Agents; Lymphocyte Count; Methotrexate; Mice; Mice, Inbred BALB C; Psoriasis; Random Allocation; RNA, Messenger; Spleen; T-Lymphocytes, Regulatory | 2018 |
Hesperidin inhibits keratinocyte proliferation and imiquimod-induced psoriasis-like dermatitis via the IRS-1/ERK1/2 pathway.
Topics: Animals; Blotting, Western; Cell Proliferation; Dermatologic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Hesperidin; Humans; Imiquimod; Keratinocytes; Lipopolysaccharides; Male; MAP Kinase Signaling System; Methotrexate; Mice; Mice, Inbred BALB C; Psoriasis; Real-Time Polymerase Chain Reaction | 2019 |
cis-Khellactone Inhibited the Proinflammatory Macrophages via Promoting Autophagy to Ameliorate Imiquimod-Induced Psoriasis.
Topics: Adjuvants, Immunologic; Animals; Autophagy; Autophagy-Related Protein 7; Beclin-1; Cells, Cultured; Coumarins; Disease Models, Animal; Female; Gene Knockdown Techniques; Hepatocytes; Humans; Imiquimod; Macrophages; Male; Methotrexate; Mice; Mice, Inbred C57BL; Primary Cell Culture; Psoriasis; Toxicity Tests | 2019 |
Development, characterization and evaluation of topical methotrexate-entrapped deformable liposome on imiquimod-induced psoriasis in a mouse model.
Topics: Administration, Cutaneous; Animals; Disease Models, Animal; Female; Folic Acid Antagonists; Imiquimod; Immunosuppressive Agents; Liposomes; Methotrexate; Mice, Inbred BALB C; Psoriasis | 2019 |
Nanoparticle-Coupled Topical Methotrexate Can Normalize Immune Responses and Induce Tissue Remodeling in Psoriasis.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Apoptosis; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Female; Gold; Humans; Imiquimod; Immunity; Methotrexate; Mice; Mice, Inbred C57BL; Nanoparticles; Psoriasis; Skin; Th17 Cells; Xenograft Model Antitumor Assays | 2020 |
Methotrexate-Loaded Nanostructured Lipid Carrier Gel Alleviates Imiquimod-Induced Psoriasis by Moderating Inflammation: Formulation, Optimization, Characterization, In-Vitro and In-Vivo Studies.
Topics: Administration, Cutaneous; Administration, Topical; Animals; Catalase; Cytokines; Drug Carriers; Drug Compounding; Drug Liberation; Gels; Glutathione; Humans; Imiquimod; Inflammation; Lipids; Malondialdehyde; Methotrexate; Mice, Inbred BALB C; Nanostructures; Organ Size; Psoriasis; Superoxide Dismutase | 2020 |
CD8-positive cutaneous lymphoproliferation associated with large granular lymphocyte leukemia in a patient with X-linked agammaglobulinemia.
Topics: Adjuvants, Immunologic; Agammaglobulinemia; Biopsy; Bone Marrow; CD8-Positive T-Lymphocytes; Dermatologic Agents; Diagnosis, Differential; Drug Therapy, Combination; Gene Rearrangement, T-Lymphocyte; Genetic Diseases, X-Linked; Histiocytes; Humans; Imiquimod; Immunosuppression Therapy; Leukemia, Large Granular Lymphocytic; Male; Methotrexate; Middle Aged; Skin; Treatment Outcome | 2021 |
Dihydroartemisinin ameliorates psoriatic skin inflammation and its relapse by diminishing CD8
Topics: Animals; Artemisinins; CD8-Positive T-Lymphocytes; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Imiquimod; Immunologic Memory; Interleukin-15; Interleukin-17; Male; Methotrexate; Mice; Psoriasis; Recurrence; Secondary Prevention; Skin; Skin Transplantation; Transplantation Chimera | 2020 |
Co-delivery of methotrexate and nicotinamide by cerosomes for topical psoriasis treatment with enhanced efficacy.
Topics: Administration, Topical; Animals; Imiquimod; Methotrexate; Mice; Mice, Inbred BALB C; Niacinamide; Psoriasis; Skin | 2021 |
Evaluation of methotrexate-loaded surfactants, ceramides and cholesterol-based lamellar phases as a topical treatment for psoriasis.
Topics: Animals; Ceramides; Cholesterol; Disease Models, Animal; Imiquimod; Methotrexate; Mice; Mice, Inbred BALB C; Psoriasis; Skin; Surface-Active Agents | 2022 |
Shikonin combined with methotrexate regulate macrophage polarization to treat psoriasis.
Topics: Animals; Imiquimod; Lipopolysaccharides; Macrophages; Methotrexate; Mice; Naphthoquinones; Psoriasis | 2022 |
Topical Delivery of ROS-Responsive Methotrexate Prodrug Nanoassemblies by a Dissolvable Microneedle Patch for Psoriasis Therapy.
Topics: Animals; Imiquimod; Methotrexate; Mice; NF-kappa B; Polyesters; Prodrugs; Psoriasis; Reactive Oxygen Species; Skin | 2023 |