imipramine and trimipramine

imipramine has been researched along with trimipramine in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199018 (40.91)18.7374
1990's6 (13.64)18.2507
2000's8 (18.18)29.6817
2010's11 (25.00)24.3611
2020's1 (2.27)2.80

Authors

AuthorsStudies
Medina-Hernández, MJ; Quiñones-Torrelo, C; Sagrado, S; Villanueva-Camañas, RM1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Bacsó, Z; Cianfriglia, M; Fenyvesi, F; Goda, K; Kappelmayer, J; Lustyik, G; Nagy, H; Szabó, G; Szilasi, M1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Bleich, S; Kornhuber, J; Rupprecht, R; Terfloth, L; Wiltfang, J1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Gozalbes, R; Pineda-Lucena, A1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Bellman, K; Knegtel, RM; Settimo, L1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cardoso, FC; Duggan, PJ; Kuiper, MJ; Lewis, RJ; Schmit, M; Tuck, KL1
Kocher, R1
Beier, R; Heim, M; Knorr, W; Kühne, GE; Perina, L; Richter, H; Rossberg, V; Sorger, R; Waldow, N1
Baba, O; Fujiwara, J; Hanaoka, M; Ishino, H; Sasaki, K1
Detaevernier, MR; Dryon, L; Massart, DL1
Handl, W; Hartvig, P; Svahn, CM; Vessman, J1
Brown, FW; Cobert, B; Moorad, PJ; Pittard, JT; Ware, JC1
Schramm, T; Töppel, A; Ziebarth, D1
Baumann, P; Cuendet, C; Eap, CB1
Coudert, B; Dwyer, TM; Joshi, UM; Kodavanti, PR; Mehendale, HM1
Conquy, T; Gouezo, F; Grimaldi, F; Pok Phak, R; Viala, A1
Cunha, UV1
Hauser, K; Häusler, A; Meeker, JB1
Juhos, E; Nagy, O; Radó, JP; Simon, T; Takó, J1
Fenyvesi, T; Floro, K1
Caillé, G; Cournoyer, G; de Montigny, C; Langlois, R; Morissette, R1
Kane, J; Klein, DF; Rifkin, A; Ross, D; Saraf, K1
Robins, E; Welner, A; Welner, Z1
Dewar, KM; Grondin, L; Nénonéné, EK; Ohayon, M; Reader, TA1
Guldner, J; Holsboer, F; Rothe, B; Sonntag, A; Steiger, A; Yassouridis, A1
Kumazawa, T; Lee, XP; Sato, K; Suzuki, O1
Hatzinger, M; Hemmeter, U; Holsboer-Trachsler, E; Müller, MJ; Seifritz, E1
Fernandez-Belda, F; Fortea, I; Plenge-Tellechea, F; Soler, F1
Booth-Genthe, CL; Grimm, SW; Guo, J; Linnenbach, AJ; Zhou, D1
Du, H; You, T; Yu, C1
Sanghavi, BJ; Srivastava, AK1
Mirmohammadi, M; Shamsipur, M1

Reviews

1 review(s) available for imipramine and trimipramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

9 trial(s) available for imipramine and trimipramine

ArticleYear
[Differential indication of trimipramine - results of a controlled multiclinical study].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1979, Volume: 31, Issue:4

    Topics: Clinical Trials as Topic; Depression; Dibenzazepines; Double-Blind Method; Drug Evaluation; Humans; Imipramine; Trimipramine

1979
Effects on sleep: a double-blind study comparing trimipramine to imipramine in depressed insomniac patients.
    Sleep, 1989, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Depressive Disorder; Dibenzazepines; Double-Blind Method; Electroencephalography; Evoked Potentials; Female; Humans; Imipramine; Male; Middle Aged; Personality Tests; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Sleep Stages; Sleep, REM; Trimipramine

1989
Lithium carbonate addition in tricyclic antidepressant-resistant unipolar depression. Correlations with the neurobiologic actions of tricyclic antidepressant drugs and lithium ion on the serotonin system.
    Archives of general psychiatry, 1983, Volume: 40, Issue:12

    Topics: Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Clinical Trials as Topic; Depressive Disorder; Desipramine; Doxepin; Drug Synergism; Drug Therapy, Combination; Female; Humans; Imipramine; Lithium; Lithium Carbonate; Male; Middle Aged; Neurons; Psychiatric Status Rating Scales; Serotonin; Trimipramine

1983
Trimipramine maleate (Surmontil)--another tricyclic antidepressant.
    The Medical letter on drugs and therapeutics, 1980, Feb-08, Volume: 22, Issue:3

    Topics: Antidepressive Agents; Clinical Trials as Topic; Depression; Dibenzazepines; Double-Blind Method; Humans; Imipramine; Trimipramine

1980
A comparison of trimipramine and imipramine: a controlled study.
    The Journal of clinical psychiatry, 1980, Volume: 41, Issue:4

    Topics: Adult; Depression; Dibenzazepines; Female; Humans; Imipramine; Male; Psychiatric Status Rating Scales; Trimipramine

1980
Effect of tricyclic antidepressants on individual symptoms.
    The Journal of clinical psychiatry, 1980, Volume: 41, Issue:9

    Topics: Affective Disorders, Psychotic; Amitriptyline; Antidepressive Agents, Tricyclic; Depressive Disorder; Humans; Imipramine; Protriptyline; Psychotropic Drugs; Trimipramine

1980
Trimipramine and imipramine exert different effects on the sleep EEG and on nocturnal hormone secretion during treatment of major depression.
    Depression, 1996, Volume: 4, Issue:1

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Cerebral Cortex; Depressive Disorder; Dopamine D2 Receptor Antagonists; Double-Blind Method; Electroencephalography; Human Growth Hormone; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Imipramine; Male; Middle Aged; Personality Inventory; Pituitary-Adrenal System; Polysomnography; Prolactin; Receptors, Dopamine D2; Sleep Stages; Testosterone; Trimipramine

1996
[New information on a classic antidepressive agent].
    Der Nervenarzt, 1994, Volume: 65, Issue:3 Suppl

    Topics: Antidepressive Agents, Tricyclic; Humans; Imipramine; Trimipramine

1994
Side effects of adjunct light therapy in patients with major depression.
    European archives of psychiatry and clinical neuroscience, 1997, Volume: 247, Issue:5

    Topics: Antidepressive Agents, Tricyclic; Combined Modality Therapy; Depressive Disorder; Female; Humans; Imipramine; Male; Middle Aged; Phototherapy; Psychiatric Status Rating Scales; Trimipramine

1997

Other Studies

34 other study(ies) available for imipramine and trimipramine

ArticleYear
Development of predictive retention-activity relationship models of tricyclic antidepressants by micellar liquid chromatography.
    Journal of medicinal chemistry, 1999, Aug-12, Volume: 42, Issue:16

    Topics: Adenylyl Cyclase Inhibitors; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents, Tricyclic; Chromatography, Liquid; Enzyme Inhibitors; Histamine H1 Antagonists; Micelles; Models, Biological; Norepinephrine; Rats; Receptors, Adrenergic, alpha-1; Selective Serotonin Reuptake Inhibitors; Serotonin; Structure-Activity Relationship

1999
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies.
    Biochemical and biophysical research communications, 2004, Mar-19, Volume: 315, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Calcium Channel Blockers; Cyclosporine; Detergents; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Humans; Ivermectin; Mice; NIH 3T3 Cells; Substrate Specificity

2004
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Molecular properties of psychopharmacological drugs determining non-competitive inhibition of 5-HT3A receptors.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:6

    Topics: Binding Sites; Computer Simulation; Databases, Factual; Models, Chemical; Models, Molecular; Molecular Structure; Molecular Weight; Psychotropic Drugs; Serotonin 5-HT3 Receptor Antagonists; Structure-Activity Relationship

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Inhibition of N-type calcium ion channels by tricyclic antidepressants - experimental and theoretical justification for their use for neuropathic pain.
    RSC medicinal chemistry, 2022, Feb-23, Volume: 13, Issue:2

    Topics:

2022
[The treatment of chronic pain symptoms with psychotropic drugs (author's transl)].
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1976, Volume: 9, Issue:6

    Topics: Antidepressive Agents, Tricyclic; Antipsychotic Agents; Bone Diseases; Clomipramine; Drug Therapy, Combination; Haloperidol; Humans; Imipramine; Neoplasms; Neuralgia; Pain; Palliative Care; Promazine; Trimipramine

1976
Effect of flupenthixol on depression with special reference to combination use with tricyclic antidepressants. An uncontrolled pilot study with 45 patients.
    Acta psychiatrica Scandinavica, 1976, Volume: 54, Issue:2

    Topics: Adolescent; Adult; Aged; Amitriptyline; Antidepressive Agents, Tricyclic; Child; Clomipramine; Depression; Drug Evaluation; Drug Therapy, Combination; Female; Flupenthixol; Humans; Imipramine; Male; Middle Aged; Nortriptyline; Pilot Projects; Thioxanthenes; Trimipramine

1976
The separation of some tricyclic antidepressants by high-performance liquid chromatography.
    Journal of chromatography, 1976, Nov-17, Volume: 128, Issue:1

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Clomipramine; Desipramine; Imipramine; Microchemistry; Nortriptyline; Protriptyline; Trimipramine

1976
Electron capture gas chromatography of tertiary amines as pentafluorobenzyl carbamates.
    Analytical chemistry, 1976, Volume: 48, Issue:2

    Topics: Carbamates; Chromatography, Gas; Fluorobenzenes; Imipramine; Indicators and Reagents; Trimipramine

1976
[Drugs from the classes of tricyclic antidepressives and antiepileptics, nitrosatable under simulated human gastric conditions].
    Archiv fur Geschwulstforschung, 1989, Volume: 59, Issue:4

    Topics: Carbamazepine; Dibenzazepines; Gastric Mucosa; Humans; Imipramine; In Vitro Techniques; Nitrites; Nitrosamines; Nitrosation; Nitroso Compounds; Trimipramine

1989
Selectivity in the binding of psychotropic drugs to the variants of alpha-1 acid glycoprotein.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 337, Issue:2

    Topics: Amitriptyline; Clomipramine; Desipramine; Hydrogen-Ion Concentration; Imipramine; Maprotiline; Methadone; Orosomucoid; Psychotropic Drugs; Thioridazine; Trimipramine

1988
Types of interaction of amphiphilic drugs with phospholipid vesicles.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1

    Topics: Amiodarone; Anilino Naphthalenesulfonates; Binding Sites; Chloramphenicol; Chloroquine; Chlorpromazine; Diphenylhexatriene; Imipramine; Lipidoses; Lung Diseases; Membrane Lipids; Phospholipids; Promethazine; Propranolol; Surface-Active Agents; Trimipramine

1988
Determination of metapramine, imipramine, trimipramine and their major metabolites in plasma by reversed-phase column liquid chromatography.
    Journal of chromatography, 1986, Mar-07, Volume: 375, Issue:2

    Topics: Antidepressive Agents, Tricyclic; Chromatography, Liquid; Dibenzazepines; Humans; Imipramine; Indicators and Reagents; Spectrophotometry, Ultraviolet; Trimipramine

1986
Antidepressants: their uses in nonpsychiatric disorders of aging.
    Geriatrics, 1986, Volume: 41, Issue:10

    Topics: Affective Symptoms; Aged; Antidepressive Agents; Chronic Disease; Colonic Diseases, Functional; Depression; Doxepin; Female; Humans; Imipramine; Male; Narcolepsy; Nomifensine; Pain; Peptic Ulcer; Protriptyline; Sleep Apnea Syndromes; Syndrome; Trimipramine; Urinary Incontinence

1986
Effects of subchronic administration of psychoactive substances on the circadian rhythm of urinary corticosterone excretion in rats.
    Psychoneuroendocrinology, 1985, Volume: 10, Issue:4

    Topics: Animals; Antidepressive Agents; Circadian Rhythm; Clorgyline; Corticosterone; Fluoxetine; Imipramine; Male; Maprotiline; Pargyline; Propylamines; Rats; Trimipramine

1985
Interference of psychotropic drugs with cortisol determinations.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1974, Volume: 6, Issue:6

    Topics: Diagnostic Errors; Humans; Hydrocortisone; Imipramine; Methods; Methotrimeprazine; Psychotropic Drugs; Spectrometry, Fluorescence; Time Factors; Trimipramine

1974
Treatment of depression with Sapilent.
    Therapia Hungarica (English edition), 1973, Volume: 21, Issue:3-4

    Topics: Adult; Aged; Antidepressive Agents; Depression; Dibenzazepines; Drug Evaluation; Humans; Imipramine; Male; Methotrimeprazine; Trimipramine

1973
[3H]paroxetine binding and serotonin content of rat brain: absence of changes following antidepressant treatments.
    European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Chromatography, High Pressure Liquid; Fluoxetine; Imipramine; Male; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin; Trimipramine

1993
Detection of tricyclic antidepressants in whole blood by headspace solid-phase microextraction and capillary gas chromatography.
    Journal of chromatographic science, 1997, Volume: 35, Issue:7

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Chromatography, Gas; Clomipramine; Humans; Imipramine; Male; Rats; Rats, Wistar; Sodium Hydroxide; Trimipramine; Water

1997
Clomipramine and related structures as inhibitors of the skeletal sarcoplasmic reticulum Ca2+ pump.
    Journal of bioenergetics and biomembranes, 2000, Volume: 32, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antidepressive Agents, Tricyclic; Calcium; Calcium-Transporting ATPases; Clomipramine; Desipramine; Enzyme Inhibitors; Imipramine; Magnesium; Muscle, Skeletal; Phosphorylation; Rabbits; Sarcoplasmic Reticulum; Trimipramine

2000
Role of human UGT2B10 in N-glucuronidation of tricyclic antidepressants, amitriptyline, imipramine, clomipramine, and trimipramine.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:5

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Biocatalysis; Clomipramine; Enzyme Inhibitors; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; Humans; Imipramine; Kinetics; Microsomes, Liver; Nicotine; Recombinant Proteins; Sapogenins; Trimipramine

2010
Determination of imipramine and trimipramine by capillary electrophoresis with electrochemiluminescence detection.
    Talanta, 2011, Feb-15, Volume: 83, Issue:5

    Topics: Antidepressive Agents, Tricyclic; Electrophoresis, Capillary; Imipramine; Limit of Detection; Luminescent Measurements; Molecular Structure; Trimipramine

2011
Adsorptive stripping voltammetric determination of imipramine, trimipramine and desipramine employing titanium dioxide nanoparticles and an Amberlite XAD-2 modified glassy carbon paste electrode.
    The Analyst, 2013, Mar-07, Volume: 138, Issue:5

    Topics: Adsorption; Antidepressive Agents, Tricyclic; Carbon; Desipramine; Electrochemical Techniques; Electrodes; Humans; Imipramine; Limit of Detection; Nanoparticles; Pharmaceutical Preparations; Reproducibility of Results; Resins, Synthetic; Titanium; Trimipramine

2013
High performance liquid chromatographic determination of ultra traces of two tricyclic antidepressant drugs imipramine and trimipramine in urine samples after their dispersive liquid-liquid microextraction coupled with response surface optimization.
    Journal of pharmaceutical and biomedical analysis, 2014, Volume: 100

    Topics: Antidepressive Agents, Tricyclic; Calibration; Chromatography, High Pressure Liquid; Humans; Imipramine; Limit of Detection; Linear Models; Liquid Phase Microextraction; Male; Models, Statistical; Multivariate Analysis; Reference Standards; Reproducibility of Results; Solvents; Spectrophotometry, Ultraviolet; Trimipramine

2014