imipramine and sulpiride

imipramine has been researched along with sulpiride in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199011 (31.43)18.7374
1990's4 (11.43)18.2507
2000's12 (34.29)29.6817
2010's8 (22.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gubernator, K; Kansy, M; Senner, F1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Caron, G; Ermondi, G1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Fresia, P; Longoni, R; Spano, PF; Trabucchi, M1
Francès, H; Puech, AJ; Simon, P1
Najima, K; Saito, M; Yoshizawa, H1
Poignant, JC; Rismondo, N1
Abe, K1
Maj, J; Rogóz, Z; Skuza, G; Sowińska, H1
Andree, TH; Koenig, JI; Meltzer, HY; Mikuni, M; Tong, CY1
Fujita, M; Horikomi, K1
Cervo, L; Samanin, R1
Fukuda, T; Kurihara, M; Setoguchi, M; Tsumagari, T1
Grandi, M; Mauceri, P; Morini, A; Pelliccia, G1
Ferri, S; Giagnoni, G; Panico, AM; Santagostino, A; Scoto, G; Spadaro, C; Speroni, E1
Fadda, P; Fratta, W; Pani, L; Porcella, A1
Boyer, P; Lecrubier, Y; Rein, W; Turjanski, S1
Papp, M; Wieronska, J1
Okuyama, S; Takamori, K; Yoshida, S1
Butterweck, V; Christoffel, V; Löhning, A; Spengler, B; Winterhoff, H1
Dhingra, D; Sharma, A1
Ikenouchi-Sugita, A; Nakamura, J; Yoshimura, R1
Costentin, J; Do Rego, JC; Müller, LG; Nunes, JM; Rates, SM; Stein, AC; Stolz, ED; Viana, AF; von Poser, GL1
Matsumoto, K; Oka, JI; Sasaki-Hamada, S; Suzuki, A; Ueda, Y1

Reviews

1 review(s) available for imipramine and sulpiride

ArticleYear
[Review of pharmacological efficacies and side effects of antidepressants].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Volume: 65, Issue:9

    Topics: Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Fluvoxamine; Humans; Imipramine; Maprotiline; Paroxetine; Sulpiride; Trazodone

2007

Trials

1 trial(s) available for imipramine and sulpiride

ArticleYear
Amisulpride versus imipramine and placebo in dysthymia and major depression. Amisulpride Study Group.
    Journal of affective disorders, 1997, Volume: 43, Issue:2

    Topics: Adult; Aged; Amisulpride; Antidepressive Agents; Antidepressive Agents, Tricyclic; Depression; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Sulpiride

1997

Other Studies

33 other study(ies) available for imipramine and sulpiride

ArticleYear
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes.
    Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7

    Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet

1998
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Sulpiride: a study of the effects on dopamine receptors in rat neostriatum and limbic forebrain.
    Life sciences, 1975, Nov-15, Volume: 17, Issue:10

    Topics: Adenylyl Cyclases; Animals; Apomorphine; Corpus Striatum; Cyclic AMP; Dopamine; Haloperidol; Imipramine; Male; Olfactory Bulb; Rats; Receptors, Drug; Sulpiride

1975
Imipramine antagonism of apomorphine-induced hypothermia: a non-dopaminergic interaction.
    European journal of pharmacology, 1978, Jan-01, Volume: 47, Issue:1

    Topics: Animals; Apomorphine; Body Temperature; Dopamine; Imipramine; Male; Mice; Pimozide; Sulpiride

1978
[Effects of amoxapine, imipramine and sulpiride on anterior pituitary hormone levels in the blood of normal subjects].
    Horumon to rinsho. Clinical endocrinology, 1978, Volume: 26, Issue:9

    Topics: Adult; Amoxapine; Dibenzoxazepines; Humans; Imipramine; Male; Pituitary Hormones, Anterior; Sulpiride

1978
[Influence of the administration of psychopharmacological compounds on the take up time of an alimentary material in the hamster and a study of the associated behaviour (author's transl)].
    Psychopharmacologia, 1975, Jul-23, Volume: 43, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Clonidine; Cricetinae; Dextroamphetamine; Diazepam; Feeding Behavior; Fenfluramine; Humans; Imipramine; Male; Meprobamate; Mesocricetus; Morphine; Motor Activity; Phenobarbital; Piribedil; Psychotropic Drugs; Stereotyped Behavior; Sulpiride; Time Factors

1975
Sulpiride in school phobia.
    Psychiatria clinica, 1975, Volume: 8, Issue:3

    Topics: Adolescent; Child; Drug Evaluation; Female; Humans; Imipramine; Male; Phobic Disorders; Remission, Spontaneous; Schools; Sulpiride

1975
The effect of antidepressant drugs on the locomotor hyperactivity induced by MK-801, a non-competitive NMDA receptor antagonist.
    Neuropharmacology, 1992, Volume: 31, Issue:7

    Topics: Animals; Antidepressive Agents; Benzazepines; Citalopram; Dizocilpine Maleate; Fluoxetine; Imipramine; Isomerism; Male; Maprotiline; Motor Activity; Prazosin; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Seizures; Sulpiride

1992
Differential effect of subchronic treatment with various neuroleptic agents on serotonin2 receptors in rat cerebral cortex.
    Journal of neurochemistry, 1986, Volume: 46, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Animals; Antipsychotic Agents; Cerebral Cortex; Chlorpromazine; Clozapine; Female; Haloperidol; Imipramine; Ketanserin; Loxapine; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Sulpiride

1986
[Comparative study of the pharmacological properties of sultopride sulpiride and other antipsychotic drugs: influence of sultopride, sulpiride and other antipsychotic drugs on spontaneous locomotor activity and changes in locomotor activity induced by apo
    Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology, 1986, Volume: 6, Issue:3

    Topics: Amisulpride; Animals; Antipsychotic Agents; Apomorphine; Chlorpromazine; Clonidine; Drug Interactions; Haloperidol; Imipramine; Male; Mice; Motor Activity; Pimozide; Sulpiride; Yohimbine

1986
Repeated treatment with imipramine and amitriptyline reduced the immobility of rats in the swimming test by enhancing dopamine mechanisms in the nucleus accumbens.
    The Journal of pharmacy and pharmacology, 1988, Volume: 40, Issue:2

    Topics: Amitriptyline; Animals; Catheterization; Dopamine; Imipramine; Male; Motor Activity; Nucleus Accumbens; Rats; Septal Nuclei; Sulpiride; Swimming

1988
A study on the pharmacological and biochemical profile of clocapramine.
    International pharmacopsychiatry, 1982, Volume: 17, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Apomorphine; Benzodiazepines; Body Temperature Regulation; Chlorpromazine; Dibenzazepines; Drug Interactions; Imipramine; Male; Methamphetamine; Motor Activity; Muridae; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Self Stimulation; Sulpiride; Tranquilizing Agents

1982
[Psychosomatic disorders considered from an internist viewpoint. II. Problems of drug therapy].
    Minerva medica, 1984, Aug-25, Volume: 75, Issue:32-33

    Topics: Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents; Dose-Response Relationship, Drug; Humans; Imipramine; Monoamine Oxidase Inhibitors; Psychophysiologic Disorders; Psychotropic Drugs; Sulpiride

1984
Pituitary endorphin levels increase after sulpiride treatment.
    Advances in biochemical psychopharmacology, 1982, Volume: 31

    Topics: Animals; Endorphins; Imipramine; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Sulpiride

1982
Chronic imipramine, L-sulpiride and mianserin decrease corticotropin releasing factor levels in the rat brain.
    Neuroscience letters, 1995, Jun-09, Volume: 192, Issue:2

    Topics: Animals; Brain; Corticotropin-Releasing Hormone; Hypothalamus; Imipramine; Male; Mianserin; Nucleus Accumbens; Olfactory Bulb; Osmolar Concentration; Rats; Rats, Sprague-Dawley; Septum Pellucidum; Sulpiride; Time Factors; Tissue Distribution

1995
Antidepressant-like activity of amisulpride in two animal models of depression.
    Journal of psychopharmacology (Oxford, England), 2000, Volume: 14, Issue:1

    Topics: Amisulpride; Animals; Antidepressive Agents; Antipsychotic Agents; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Imipramine; Male; Motivation; Motor Activity; Rats; Rats, Wistar; Sulpiride; Treatment Outcome

2000
Repeated treatment with imipramine, fluvoxamine and tranylcypromine decreases the number of escape failures by activating dopaminergic systems in a rat learned helplessness test.
    Life sciences, 2001, Sep-07, Volume: 69, Issue:16

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antidepressive Agents; Benzazepines; Disease Models, Animal; Dopamine Agonists; Dopamine Antagonists; Escape Reaction; Fluvoxamine; Helplessness, Learned; Imipramine; Male; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine; Sulpiride; Tetrahydronaphthalenes; Tranylcypromine

2001
Cimicifuga extract BNO 1055: reduction of hot flushes and hints on antidepressant activity.
    Maturitas, 2003, Mar-14, Volume: 44 Suppl 1

    Topics: Animals; Behavior, Animal; Body Temperature; Cimicifuga; Depression; Dose-Response Relationship, Drug; Estrogens; Female; Hot Flashes; Imipramine; Menopause; Mice; Models, Animal; Ovariectomy; Phytotherapy; Plant Extracts; Rats; Rats, Wistar; Sulpiride

2003
Antidepressant-like activity of n-hexane extract of nutmeg (Myristica fragrans) seeds in mice.
    Journal of medicinal food, 2006,Spring, Volume: 9, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Dopamine Antagonists; Drug Interactions; Fenclonine; Fluoxetine; Hexanes; Imipramine; Male; Mice; Motor Activity; Myristica; Plant Extracts; Prazosin; Seeds; Serotonin Antagonists; Sulpiride; Swimming

2006
Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: a promising new molecular pattern for the development of antidepressant drugs.
    Behavioural brain research, 2012, Mar-01, Volume: 228, Issue:1

    Topics: Animals; Antidepressive Agents; Benzazepines; Biogenic Monoamines; Bupropion; Drug Evaluation, Preclinical; Enzyme Inhibitors; Fenclonine; Fluoxetine; Hypericum; Imipramine; Immobility Response, Tonic; Locomotion; Male; Mice; Mice, Inbred Strains; Phloroglucinol; Plant Extracts; Prazosin; Rats; Rats, Wistar; Receptors, Catecholamine; Sulpiride; Vesicular Monoamine Transport Proteins; Yohimbine

2012
Serotonergic and dopaminergic systems are implicated in antidepressant-like effects of chotosan, a Kampo formula, in mice.
    Journal of pharmacological sciences, 2017, Volume: 133, Issue:2

    Topics: Animals; Antidepressive Agents; Disease Models, Animal; Dopamine Agents; Drugs, Chinese Herbal; Fenclonine; Imipramine; Ketanserin; Locomotion; Male; Medicine, Kampo; Metergoline; Mice; Piperazines; Pyridines; Serotonin Agents; Sulpiride; Swimming; Yohimbine

2017