imipramine and spiperone

imipramine has been researched along with spiperone in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199019 (86.36)18.7374
1990's2 (9.09)18.2507
2000's0 (0.00)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Bauer, C; Caldwell, L; Kinnier, WJ; Lancaster, J; McMillan, B; Price, CH; Sweetnam, PM1
Artursson, P; Mateus, A; Matsson, P1
Kuruma, I; Okada, T; Seki, Y1
Klimek, V; Maj, J; Rawlów, A; Sarnek, J1
Klimek, V; Maj, J1
Mizuta, T; Segawa, T1
Maj, J; Wedzony, K1
Andree, TH; Koenig, JI; Meltzer, HY; Mikuni, M; Tong, CY1
Biassoni, R; Vaccari, A1
Arbilla, S; Bartholini, G; Claustre, Y; Dedek, J; Dennis, T; Langer, SZ; Lloyd, KG; Scatton, B; Zivkovic, B1
Garattini, S; Mennini, T; Mocaer, E1
Costa, T; Gajdusek, DC; Gibbs, CJ; Munson, PJ; Pocchiari, M1
Antkiewicz-Michaluk, L; Rokosz-Pelc, A; Vetulani, J1
Agnati, LF; Andersson, K; Benfenati, F; Eneroth, P; Fredholm, B; Fuxe, K; Ogren, SO; Zini, I1
Burrows, GD; Fulton, A; Norman, T1
Burrows, GD; Cheng, H; Fulton, A; Norman, TR1
Agnati, LF; Benfenati, F; Fuxe, K; Ogren, SO1
Dumbrille-Ross, A; Tang, SW1
Kafka, MS; Naber, D; Wehr, TA; Wirz-Justice, A1
Koide, T; Matsushita, H1
Jagadeesh, S; Subhash, MN1

Reviews

3 review(s) available for imipramine and spiperone

ArticleYear
The role of receptor binding in drug discovery.
    Journal of natural products, 1993, Volume: 56, Issue:4

    Topics: Animals; Drug Design; Humans; Receptors, Drug

1993
Chronic antidepressant treatment and central 5-HT synapses.
    Neuropharmacology, 1983, Volume: 22, Issue:3 Spec No

    Topics: Animals; Antidepressive Agents; Carrier Proteins; Corticosterone; Cyclic AMP; Dihydroalprenolol; Hippocampus; Humans; Imipramine; Lysergic Acid Diethylamide; Pituitary Hormones, Anterior; Receptors, Drug; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin; Spiperone; Substance P

1983
Central 5-HT neurons as targets for antidepressant drug action: differential modulation of 5-HT receptor populations in the central nervous system of the rat.
    Advances in biochemical psychopharmacology, 1984, Volume: 39

    Topics: Animals; Antidepressive Agents; Autoradiography; Avoidance Learning; Binding Sites; Central Nervous System; Desipramine; Histocytochemistry; Imipramine; Immunochemistry; Methoxydimethyltryptamines; Movement; Rats; Receptors, Serotonin; Spiperone; Zimeldine

1984

Other Studies

19 other study(ies) available for imipramine and spiperone

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
A possible intraneuronal site of action of thymoleptics.
    Psychopharmacology, 1979, May-08, Volume: 63, Issue:1

    Topics: Adenosine Triphosphate; Animals; Antidepressive Agents; Brain; Catecholamines; Corpus Striatum; Dopamine; Hypothalamus; Imipramine; In Vitro Techniques; Male; Mitochondria; Neurons; Norepinephrine; Rats; Reserpine; Spiperone; Synaptosomes

1979
On the anticataleptic action of cyproheptadine.
    Pharmacology, biochemistry, and behavior, 1976, Volume: 5, Issue:2

    Topics: Animals; Atropine; Catalepsy; Clomipramine; Cyproheptadine; Desipramine; Female; Fluphenazine; Humans; Imipramine; Male; Methyltyrosines; Pilocarpine; Pimozide; Promethazine; Rats; Reserpine; Spiperone

1976
Repeated administration of antidepressants enhances agonist affinity for mesolimbic D2-receptors.
    The Journal of pharmacy and pharmacology, 1989, Volume: 41, Issue:8

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Binding, Competitive; Ergolines; Imipramine; Limbic System; Male; Mianserin; Motor Activity; Norepinephrine; Quinpirole; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Spiperone

1989
Chronic effects of imipramine and lithium on 5-HT receptor subtypes in rat frontal cortex, hippocampus and choroid plexus: quantitative receptor autoradiographic analysis.
    Japanese journal of pharmacology, 1989, Volume: 50, Issue:3

    Topics: Animals; Autoradiography; Brain Chemistry; Cerebral Cortex; Choroid Plexus; Hippocampus; Imipramine; Iodine Radioisotopes; Ketanserin; Lithium; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone

1989
Repeated treatment with imipramine or amitriptyline increases the locomotor response of rats to (+)-amphetamine given into the nucleus accumbens.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:5

    Topics: Amitriptyline; Animals; Dextroamphetamine; Imipramine; Injections; Male; Motor Activity; Nucleus Accumbens; Rats; Rats, Inbred Strains; Spiperone

1985
Differential effect of subchronic treatment with various neuroleptic agents on serotonin2 receptors in rat cerebral cortex.
    Journal of neurochemistry, 1986, Volume: 46, Issue:1

    Topics: 5,7-Dihydroxytryptamine; Animals; Antipsychotic Agents; Cerebral Cortex; Chlorpromazine; Clozapine; Female; Haloperidol; Imipramine; Ketanserin; Loxapine; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Sulpiride

1986
Selective effects of thiol reagents on the binding sites for imipramine and neurotransmitter amines in the rat brain.
    British journal of pharmacology, 1985, Volume: 85, Issue:2

    Topics: Animals; Brain; Carrier Proteins; Dithionitrobenzoic Acid; Dithiothreitol; Ethylmaleimide; Hydroxymercuribenzoates; Imipramine; Male; Mercaptoethanol; Methimazole; Propylthiouracil; Rats; Receptors, Dopamine; Receptors, Drug; Receptors, Neurotransmitter; Serotonin; Spiperone; Sulfhydryl Reagents

1985
Fengabine, a novel antidepressant GABAergic agent. II. Effect on cerebral noradrenergic, serotonergic and GABAergic transmission in the rat.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Animals; Antidepressive Agents; Brain; Chlorophenols; Clonidine; Dihydroalprenolol; gamma-Aminobutyric Acid; Imipramine; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Serotonin; Spiperone; Synaptic Transmission

1987
Tianeptine, a selective enhancer of serotonin uptake in rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:5

    Topics: Animals; Brain; Cerebral Cortex; Clonidine; Dihydroalprenolol; Dopamine; Hippocampus; Imipramine; In Vitro Techniques; Male; Mesencephalon; Norepinephrine; Rats; Serotonin; Spiperone; Synaptosomes; Thiazepines

1987
Serotoninergic system in scrapie-infected hamsters.
    Journal of neurochemistry, 1985, Volume: 44, Issue:3

    Topics: Animals; Cricetinae; Female; Imipramine; Kinetics; Lysergic Acid Diethylamide; Mesocricetus; Receptors, Serotonin; Scrapie; Serotonin; Sheep; Spiperone

1985
Chronic administration of antidepressant drugs increases the density of cortical [3H]prazosin binding sites in the rat.
    Brain research, 1984, Sep-24, Volume: 310, Issue:2

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Binding Sites; Cerebral Cortex; Chlorprothixene; Citalopram; Imipramine; Male; Methotrimeprazine; Prazosin; Propylamines; Quinazolines; Rats; Rats, Inbred Strains; Spiperone

1984
Ligand binding and platelet uptake studies of loxapine, amoxapine and their 8-hydroxylated derivatives.
    Journal of affective disorders, 1982, Volume: 4, Issue:2

    Topics: Amoxapine; Animals; Binding, Competitive; Blood Platelets; Brain; Dibenzoxazepines; Imipramine; Loxapine; Rats; Rats, Inbred Lew; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Spiperone

1982
Assessment of the antidepressant activity of dothiepin and its metabolites by preclinical tests.
    Journal of affective disorders, 1982, Volume: 4, Issue:3

    Topics: Animals; Binding, Competitive; Blood Platelets; Carrier Proteins; Cerebral Cortex; Depressive Disorder; Dibenzothiepins; Dothiepin; Hippocampus; Humans; Imipramine; Rats; Rats, Inbred Lew; Receptors, Drug; Receptors, Serotonin; Serotonin; Spiperone

1982
Noradrenergic and serotonergic input necessary for imipramine-induced changes in beta but not S2 receptor densities.
    Psychiatry research, 1983, Volume: 9, Issue:3

    Topics: Animals; Dihydroalprenolol; Hydroxydopamines; Imipramine; Male; Norepinephrine; Oxidopamine; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Spiperone; Tritium

1983
Dopamine receptor binding in rat striatum: ultradian rhythm and its modification by chronic imipramine.
    Psychopharmacology, 1980, Volume: 68, Issue:1

    Topics: Animals; Corpus Striatum; Imipramine; Kinetics; Male; Periodicity; Rats; Receptors, Dopamine; Spiperone

1980
An enhanced sensitivity of muscarinic cholinergic receptor associated with dopaminergic receptor subsensitivity after chronic antidepressant treatment.
    Life sciences, 1981, Mar-09, Volume: 28, Issue:10

    Topics: Animals; Corpus Striatum; Desipramine; Imipramine; Kinetics; Male; Quinuclidinyl Benzilate; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Muscarinic; Spiperone; Tritium

1981
Imipramine-induced changes in 5-HT2 receptor sites and inositoltrisphosphate levels in rat brain.
    Neurochemical research, 1997, Volume: 22, Issue:9

    Topics: Animals; Antidepressive Agents, Tricyclic; Cerebral Cortex; Drug Evaluation, Preclinical; Imipramine; Inositol 1,4,5-Trisphosphate; Male; Phosphatidylinositols; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Spiperone

1997