imipramine has been researched along with selegiline in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (30.00) | 18.7374 |
| 1990's | 4 (13.33) | 18.2507 |
| 2000's | 9 (30.00) | 29.6817 |
| 2010's | 8 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Alencar, N; Di Pietro, O; Esteban, G; Juárez-Jiménez, J; Luque, FJ; Muñoz-Torrero, D; Pérez, B; Sola, I; Solé, M; Szałaj, N; Unzeta, M; Vázquez, J; Viayna, E | 1 |
| Alcaro, S; Bagetta, D; Borges, F; Cagide, F; Oliveira, PJ; Ortuso, F; Pérez, C; Reis, J; Rodríguez-Franco, MI; Teixeira, J; Uriarte, E; Valencia, ME | 1 |
| Nag, M; Nandi, N | 1 |
| Agosti, V; Quitkin, FM; Stewart, JW | 1 |
| Anderson, B; Severson, JA | 1 |
| Blau, M; Carmel, A; Delmon, L; Holman, BL; Johnson, D; Moingeon, P; Moretti, JL | 1 |
| Bizière, K; Kan, JP; Roncucci, R; Wermuth, CG; Worms, P | 1 |
| Knoll, B; Knoll, J; Timar, J | 1 |
| Chadwick, A; Hall, TR; Harvey, S | 1 |
| Barbaccia, ML; Costa, E; Gandolfi, O; Knoll, J; Zsilla, G | 1 |
| Barbaccia, ML; Costa, E; Gandolfi, O | 1 |
| Asnis, GM; Endicott, J; Halbreich, U; Nathan, RS; Novacenko, H; Ostrow, L; Sachar, EJ | 1 |
| Griffiths, HR; Lambert, DG; Lunec, J; Willets, JM | 1 |
| Barros, HM; Ferigolo, M; Marquardt, AR; Tannhauser, M | 1 |
| Cano, E; Fraiz, N; Orallo, F; Yáñez, M | 1 |
1 review(s) available for imipramine and selegiline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for imipramine and selegiline
| Article | Year |
|---|---|
Life satisfaction and psychosocial functioning in chronic depression: effect of acute treatment with antidepressants.
Topics: Activities of Daily Living; Adult; Antidepressive Agents; Chronic Disease; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Imipramine; Male; Personal Satisfaction; Personality Tests; Phenelzine; Selegiline; Single-Blind Method; Social Adjustment | 1991 |
28 other study(ies) available for imipramine and selegiline
| Article | Year |
|---|---|
2,4-Dihydro-3H-1,2,4-triazole-3-thiones as potential antidepressant agents.
Topics: Animals; Antidepressive Agents; Desipramine; gamma-Aminobutyric Acid; Male; Mice; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Triazoles | 1988 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors.
Topics: Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Structure-Activity Relationship | 2016 |
Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.
Topics: Alzheimer Disease; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Chromones; Drug Design; Hep G2 Cells; Humans; Ligands; Molecular Docking Simulation; Molecular Targeted Therapy; Monoamine Oxidase; Monoamine Oxidase Inhibitors | 2018 |
Antidepressants and brain respiration.
Topics: Amphetamine; Animals; Antidepressive Agents; Brain; Chlorides; Chlorpromazine; Clorgyline; Glucose; Imipramine; Lithium; Lithium Chloride; Male; Oxygen Consumption; Rats; Selegiline; Tranylcypromine | 1991 |
Chronic antidepressant treatment and mouse brain 3H-imipramine binding.
Topics: Animals; Antidepressive Agents; Binding Sites; Cerebral Cortex; Desipramine; Haloperidol; Imipramine; Male; Mice; Mice, Inbred C57BL; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Dopamine D2; Selegiline | 1986 |
Effect of antidepressant and narcoleptic drugs on N-isopropyl p-iodoamphetamine biodistribution in animals.
Topics: Amphetamines; Animals; Drug Interactions; Imipramine; Iodine Radioisotopes; Iofetamine; Male; Phenelzine; Phenethylamines; Rabbits; Rats; Receptors, Adrenergic, beta; Receptors, GABA-A; Receptors, Muscarinic; Selegiline; Tissue Distribution | 1987 |
SR 95191, a selective inhibitor of type A monoamine oxidase with dopaminergic properties. I. Psychopharmacological profile in rodents.
Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Body Temperature; Catalepsy; Clorgyline; Drug Interactions; Female; Haloperidol; Imipramine; Levodopa; Male; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Nomifensine; Oxotremorine; Pargyline; Piperidines; Pyridazines; Rats; Rats, Inbred Strains; Reserpine; Selegiline; Stereotyped Behavior | 1987 |
Long-term administration of (-)deprenyl (selegiline), a compound which facilitates dopaminergic tone in the brain, leaves the sensitivity of dopamine receptors to apomorphine unchanged.
Topics: Animals; Apomorphine; Clorgyline; Dextroamphetamine; Drug Interactions; Female; Haloperidol; Imipramine; Male; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Selegiline; Stereotyped Behavior | 1986 |
Mechanism of serotonin effects on prolactin and growth hormone secretion in domestic fowl.
Topics: alpha-Methyltyrosine; Animals; Brain; Chickens; Clorgyline; Fenclonine; Growth Hormone; Imipramine; Male; Methyltyrosines; Pargyline; Prolactin; Receptors, Serotonin; Selegiline; Serotonin; Tryptophan | 1983 |
(-)-Deprenyl a selective MAO "B' inhibitor, increases [3H]imipramine binding and decreases beta-adrenergic receptor function.
Topics: Animals; Dextroamphetamine; Hippocampus; Imipramine; Kinetics; Male; Norepinephrine; Pargyline; Phenethylamines; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Adrenergic; Receptors, Adrenergic, beta; Selegiline; Synaptic Membranes | 1983 |
The (-)-deprenyl actions on beta-adrenergic receptors require the integrity of brain serotonergic axon terminals.
Topics: 5,7-Dihydroxytryptamine; Animals; Axons; Cerebral Cortex; Cyclic AMP; Dihydroalprenolol; Imipramine; Male; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Selegiline; Serotonin; Synaptic Membranes | 1984 |
The dexamethasone suppression test in depressive illness: clinical correlates.
Topics: Depressive Disorder; Desipramine; Dexamethasone; Diagnosis, Differential; Double-Blind Method; Doxepin; Electroconvulsive Therapy; Female; Humans; Hydrocortisone; Imipramine; Male; Mianserin; Middle Aged; Nortriptyline; Phenelzine; Psychiatric Status Rating Scales; Selegiline | 1982 |
Studies on the neurotoxicity of 6,7-dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline (salsolinol) in SH-SY5Y cells.
Topics: Adenylyl Cyclases; Adrenergic Uptake Inhibitors; Catecholamines; Cell Death; Clorgyline; Dose-Response Relationship, Drug; Guanylate Cyclase; Humans; Imipramine; Indoles; Isoquinolines; L-Lactate Dehydrogenase; Monoamine Oxidase Inhibitors; Neuroblastoma; Neurotoxins; Nitroprusside; Receptors, Muscarinic; Selegiline; Tumor Cells, Cultured | 1995 |
Comparison of behavioral effects of moclobemide and deprenyl during forced swimming.
Topics: Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Benzamides; Imipramine; Male; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Phenethylamines; Psychotropic Drugs; Rats; Rats, Wistar; Selegiline; Swimming | 1998 |
(-)-Trans-epsilon-viniferin, a polyphenol present in wines, is an inhibitor of noradrenaline and 5-hydroxytryptamine uptake and of monoamine oxidase activity.
Topics: Animals; Benzofurans; Blood Platelets; Brain; Cell Line; Citalopram; Clorgyline; Dose-Response Relationship, Drug; Fluoxetine; Humans; Imipramine; Iproniazid; Isoenzymes; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Selegiline; Serotonin; Stilbenes; Synaptosomes; Tritium; Wine | 2006 |