Compounds > imipramine

imipramine and rolipram

imipramine has been researched along with rolipram in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's5 (31.25)18.2507
2000's3 (18.75)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Browne, RG; Howard, HR; Koe, BK; Lebel, LA; Sarges, R; Seymour, PA1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Bucki, A; Chrzanowska, A; Czopek, A; Drop, M; Głuch-Lutwin, M; Kołaczkowski, M; Partyka, A; Pawłowski, M; Pękala, E; Siwek, A; Struga, M; Wesołowska, A; Zagórska, A1
Rösch, H; Schultz, JE1
Fichte, K; Meya, U1
Fellerer, K; Fichte, K; Fischer, G; Geyer, N; Hebenstreit, GF; Meya, U; Sastre-y-Hernández, M; Schöny, W; Schratzer, M; Soukop, W1
Schneider, HH; Wachtel, H1
Bertolino, A; Crippa, D; di Dio, S; Fichte, K; Musmeci, G; Porro, V; Rapisarda, V; Sastre-y-Hernández, M; Schratzer, M1
Lasoń, W; Majeed, NH; Przewłocka, B; Przewłocki, R1
Wachtel, H1
Duman, RS; Nestler, EJ; Nibuya, M1
Fernández, AG; Palacios, JM; Silvestre, JS1
Abe, K; Itoh, T; Tokumura, M1
Staines, DR1
Crescenzo, MS; D'Sa, C; Duman, RS; Fujita, M; Gee, AD; Green, MV; Hong, J; Imaizumi, M; Innis, RB; Musachio, JL; Pike, VW; Seidel, J; Zoghbi, SS1
Ammassari-Teule, M; Marchetti, C; Marie, H; Middei, S; Restivo, L; Rubinacci, MA; Tafi, E1

Trials

3 trial(s) available for imipramine and rolipram

ArticleYear
[Onset of the antidepressive effect of rolipram, an antidepressant with a new mechanism of action, in comparison with imipramine].
    Der Nervenarzt, 1991, Volume: 62, Issue:5

    Topics: Antidepressive Agents; Depressive Disorder; Drug Administration Schedule; Humans; Imipramine; Personality Tests; Pyrrolidinones; Rolipram

1991
Rolipram in major depressive disorder: results of a double-blind comparative study with imipramine.
    Pharmacopsychiatry, 1989, Volume: 22, Issue:4

    Topics: Adult; Aged; Antidepressive Agents; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Pyrrolidinones; Random Allocation; Rolipram

1989
Rolipram versus imipramine in inpatients with major, "minor" or atypical depressive disorder: a double-blind double-dummy study aimed at testing a novel therapeutic approach.
    International clinical psychopharmacology, 1988, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depressive Disorder; Double-Blind Method; Female; Hospitalization; Humans; Imipramine; Male; Middle Aged; Psychiatric Status Rating Scales; Pyrrolidinones; Rolipram

1988

Other Studies

13 other study(ies) available for imipramine and rolipram

ArticleYear
4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:8

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antidepressive Agents; Behavior, Animal; Caffeine; Cats; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Corpus Striatum; Male; Molecular Structure; Motor Activity; Purinergic Antagonists; Quinoxalines; Rats; Receptors, Purinergic; Sleep; Structure-Activity Relationship; Triazoles

1990
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Novel multitarget 5-arylidenehydantoins with arylpiperazinealkyl fragment: Pharmacological evaluation and investigation of cytotoxicity and metabolic stability.
    Bioorganic & medicinal chemistry, 2019, 09-15, Volume: 27, Issue:18

    Topics: Animals; Antidepressive Agents; Depression; Disease Models, Animal; Humans; Receptors, Serotonin; Structure-Activity Relationship

2019
Differential effects of ovarian steroid hormones on beta-adrenoceptor downregulation caused by the antidepressants imipramine and rolipram.
    Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:4

    Topics: Animals; Antidepressive Agents; Body Weight; Cerebral Cortex; Down-Regulation; Estrone; Female; Gonadal Steroid Hormones; Imipramine; Male; Orchiectomy; Ovariectomy; Ovary; Pregnancy; Progesterone; Pyrrolidinones; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Neurotransmitter; Rolipram

1991
Rolipram, a novel antidepressant drug, reverses the hypothermia and hypokinesia of monoamine-depleted mice by an action beyond postsynaptic monoamine receptors.
    Neuropharmacology, 1986, Volume: 25, Issue:10

    Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; alpha-Methyltyrosine; Animals; Antidepressive Agents; Biogenic Amines; Body Temperature; Fenclonine; Imipramine; Male; Methyltyrosines; Mice; Motor Activity; Pargyline; Phosphodiesterase Inhibitors; Pyrimidines; Pyrrolidinones; Reserpine; Rolipram

1986
Antidepressants and endogenous opioid peptide systems.
    Neuropeptides, 1985, Volume: 5, Issue:4-6

    Topics: Animals; Antidepressive Agents; Brain Chemistry; Chlorprothixene; Citalopram; Endorphins; Imipramine; Male; Methotrimeprazine; Pituitary Gland, Anterior; Propylamines; Pyrrolidinones; Rats; Rats, Inbred Strains; Rolipram

1985
Potential antidepressant activity of rolipram and other selective cyclic adenosine 3',5'-monophosphate phosphodiesterase inhibitors.
    Neuropharmacology, 1983, Volume: 22, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antidepressive Agents; Body Temperature; Drug Interactions; Imipramine; Male; Mice; Motor Activity; Phosphodiesterase Inhibitors; Pyrrolidinones; Reserpine; Rolipram; Yohimbine

1983
Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Apr-01, Volume: 16, Issue:7

    Topics: 1-Naphthylamine; Animals; Antidepressive Agents; Base Sequence; Blotting, Northern; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Desipramine; Electric Stimulation; Fluoxetine; Hippocampus; Imipramine; In Situ Hybridization; Male; Molecular Sequence Data; Nerve Growth Factors; Nerve Tissue Proteins; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, trkB; Receptors, Nerve Growth Factor; RNA, Messenger; Rolipram; Sertraline; Time Factors; Tranylcypromine

1996
Effects of rolipram on the elevated plus-maze test in rats: a preliminary study.
    Journal of psychopharmacology (Oxford, England), 1999, Volume: 13, Issue:3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Anxiety; Diazepam; Imipramine; Male; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Rolipram

1999
Effects of rolipram, a phosphodiesterase 4 inhibitor, in combination with imipramine on depressive behavior, CRE-binding activity and BDNF level in learned helplessness rats.
    European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Corpus Striatum; Corticosterone; Cyclic AMP Response Element-Binding Protein; Cyclic Nucleotide Phosphodiesterases, Type 4; Depressive Disorder; Drug Synergism; Electrophoretic Mobility Shift Assay; Electroshock; Enzyme-Linked Immunosorbent Assay; Escape Reaction; Frontal Lobe; Helplessness, Learned; Hippocampus; Imipramine; Male; Phosphodiesterase Inhibitors; Protein Binding; Rats; Rats, Sprague-Dawley; Rolipram

2004
Phosphodiesterase inhibitors may be indicated in the treatment of postulated vasoactive neuropeptide autoimmune fatigue-related disorders.
    Medical hypotheses, 2006, Volume: 66, Issue:1

    Topics: Autoimmune Diseases; Cyclic AMP; Fatigue Syndrome, Chronic; Humans; Imipramine; Neuropeptides; Phosphodiesterase Inhibitors; Rolipram

2006
In vivo and in vitro measurement of brain phosphodiesterase 4 in rats after antidepressant administration.
    Synapse (New York, N.Y.), 2007, Volume: 61, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Antidepressive Agents; Blotting, Western; Brain; Brain Mapping; Carbon Isotopes; Cyclic Nucleotide Phosphodiesterases, Type 4; Image Processing, Computer-Assisted; Imipramine; In Vitro Techniques; Male; Phosphodiesterase Inhibitors; Positron-Emission Tomography; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rolipram; Time Factors; Tritium

2007
Synaptic adaptations of CA1 pyramidal neurons induced by a highly effective combinational antidepressant therapy.
    Biological psychiatry, 2010, Jan-15, Volume: 67, Issue:2

    Topics: Animals; Animals, Newborn; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; CA1 Region, Hippocampal; Dendritic Spines; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Escape Reaction; Excitatory Amino Acid Agonists; Gene Expression Regulation; Green Fluorescent Proteins; Imipramine; Immobility Response, Tonic; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; Patch-Clamp Techniques; Proto-Oncogene Proteins c-fos; Pyramidal Cells; Rats; Rats, Wistar; Rolipram; Swimming; Synapses; Synaptic Transmission

2010